OPRM1 c.643+31G>A

Variant ID: 6-154411344-G-A

NM_000914.3(OPRM1):c.643+31G>A

This variant was identified in 26 publications

View GRCh38 version.




Publications:


Alternative Pre-mRNA Splicing of the Mu Opioid Receptor Gene, OPRM1: Insight into Complex Mu Opioid Actions.

Biomolecules
Liu, Shan S; Kang, Wen-Jia WJ; Abrimian, Anna A; Xu, Jin J; Cartegni, Luca L; Majumdar, Susruta S; Hesketh, Patrick P; Bekker, Alex A; Pan, Ying-Xian YX
Publication Date: 2021-10-15

Variant appearance in text: rs9479757
PubMed Link: 34680158
Variant Present in the following documents:
  • Main text
  • biomolecules-11-01525.pdf
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A review of the pharmacogenomics of buprenorphine for the treatment of opioid use disorder.

Journal Of Translational Genetics And Genomics
Seguí, Hemanuel Arroyo HA; Melin, Kyle K; Quiñones, Darlene Santiago DS; Duconge, Jorge J
Publication Date: 2020

Variant appearance in text: rs9479757
PubMed Link: 33274315
Variant Present in the following documents:
  • Main text
  • nihms-1619690.pdf
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Trainee Posters Presented at the 121st Virtual Annual Meeting of the American Association of Colleges of Pharmacy, July 13-31, 2020.

American Journal Of Pharmaceutical Education
Publication Date: 2020-06

Variant appearance in text: rs9479757
PubMed Link: 32665733
Variant Present in the following documents:
  • Main text
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Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders.

Frontiers In Psychiatry
Burns, Jamie A JA; Kroll, Danielle S DS; Feldman, Dana E DE; Kure Liu, Christopher C; Manza, Peter P; Wiers, Corinde E CE; Volkow, Nora D ND; Wang, Gene-Jack GJ
Publication Date: 2019

Variant appearance in text: rs9479757
PubMed Link: 31620026
Variant Present in the following documents:
  • Main text
  • fpsyt-10-00626.pdf
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Lack of Association between Opioid-Receptor Genotypes and Smoking Cessation Outcomes in a Randomized, Controlled Naltrexone Trial.

Alcohol And Alcoholism (Oxford, Oxfordshire)
Roche, Daniel J O DJO; Trela, Constantine J CJ; Argos, Maria M; Jasmine, Farzana F; Kibriya, Muhammad G MG; Ahsan, Habibul H; King, Andrea C AC
Publication Date: 2019-01-09

Variant appearance in text: rs9479757
PubMed Link: 31206155
Variant Present in the following documents:
  • Main text
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Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.

Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27

Variant appearance in text: OPRM1: 643+31G>A; rs9479757
PubMed Link: 30814510
Variant Present in the following documents:
  • 41419_2019_1453_MOESM27_ESM.xlsx, sheet 1
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Pain polymorphisms and opioids: An evidence based review.

Molecular Medicine Reports
Vieira, Cláudia Margarida Pereira CMP; Fragoso, Rosa Maria RM; Pereira, Deolinda D; Medeiros, Rui R
Publication Date: 2019-03

Variant appearance in text: rs9479757
PubMed Link: 30592275
Variant Present in the following documents:
  • Main text
  • mmr-19-03-1423.pdf
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Genetic Evidence Supporting the Role of the Calcium Channel, CACNA1S, in Tooth Cusp and Root Patterning.

Frontiers In Physiology
Laugel-Haushalter, Virginie V; Morkmued, Supawich S; Stoetzel, Corinne C; Geoffroy, Véronique V; Muller, Jean J; Boland, Anne A; Deleuze, Jean-François JF; Chennen, Kirsley K; Pitiphat, Waranuch W; Dollfus, Hélène H; Niederreither, Karen K; Bloch-Zupan, Agnès A; Pungchanchaikul, Patimaporn P
Publication Date: 2018

Variant appearance in text: rs9479757
PubMed Link: 30319441
Variant Present in the following documents:
  • Table_5.xlsx, sheet 1
View BVdb publication page



PharmGKB summary: oxycodone pathway, pharmacokinetics.

Pharmacogenetics And Genomics
Huddart, Rachel R; Clarke, Melissa M; Altman, Russ B RB; Klein, Teri E TE
Publication Date: 2018-10

Variant appearance in text: rs9479757
PubMed Link: 30222708
Variant Present in the following documents:
  • Main text
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Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes.

The Pharmacogenomics Journal
Choi, Jihoon J; Tantisira, Kelan G KG; Duan, Qing Ling QL
Publication Date: 2019-04

Variant appearance in text: rs9479757
PubMed Link: 30214008
Variant Present in the following documents:
  • NIHMS1503453-supplement-3.xlsx, sheet 1
View BVdb publication page



Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning.

Bmc Research Notes
Olesen, Anne Estrup AE; Grønlund, Debbie D; Gram, Mikkel M; Skorpen, Frank F; Drewes, Asbjørn Mohr AM; Klepstad, Pål P
Publication Date: 2018-01-27

Variant appearance in text: rs9479757
PubMed Link: 29374492
Variant Present in the following documents:
  • Main text
  • 13104_2018_Article_3194.pdf
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Truncated μ-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia.

Anesthesia And Analgesia
Lu, Zhigang Z; Xu, Jin J; Xu, Mingming M; Rossi, Grace C GC; Majumdar, Susruta S; Pasternak, Gavril W GW; Pan, Ying-Xian YX
Publication Date: 2018-03

Variant appearance in text: rs9479757
PubMed Link: 28991118
Variant Present in the following documents:
  • Main text
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Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity.

Plos Genetics
Yazdani, Neema N; Parker, Clarissa C CC; Shen, Ying Y; Reed, Eric R ER; Guido, Michael A MA; Kole, Loren A LA; Kirkpatrick, Stacey L SL; Lim, Jackie E JE; Sokoloff, Greta G; Cheng, Riyan R; Johnson, W Evan WE; Palmer, Abraham A AA; Bryant, Camron D CD
Publication Date: 2015-12

Variant appearance in text: rs9479757
PubMed Link: 26658939
Variant Present in the following documents:
  • Main text
  • pgen.1005713.pdf
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RNA-binding proteins, neural development and the addictions.

Genes, Brain, And Behavior
Bryant, C D CD; Yazdani, N N
Publication Date: 2016-01

Variant appearance in text: rs9479757
PubMed Link: 26643147
Variant Present in the following documents:
  • Main text
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Poster Session IMonday, December 7, 2015.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Publication Date: 2015-12

Variant appearance in text: rs9479757
PubMed Link: 26632286
Variant Present in the following documents:
  • Main text
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The Opposing Roles of IVS2+691 CC Genotype and AC/AG Diplotype of 118A>G and IVS2+691G>C of OPRM1 Polymorphisms in Cold Pain Tolerance Among Opioid-Dependent Malay Males on Methadone Therapy.

Pain And Therapy
Zahari, Zalina Z; Lee, Chee Siong CS; Ibrahim, Muslih Abdulkarim MA; Musa, Nurfadhlina N; Yasin, Mohd Azhar Mohd MA; Lee, Yeong Yeh YY; Tan, Soo Choon SC; Mohamad, Nasir N; Ismail, Rusli R
Publication Date: 2015-12

Variant appearance in text: rs9479757
PubMed Link: 26581429
Variant Present in the following documents:
  • Main text
View BVdb publication page



Regional brain [(11)C]carfentanil binding following tobacco smoking.

Progress In Neuro-Psychopharmacology & Biological Psychiatry
Domino, Edward F EF; Hirasawa-Fujita, Mika M; Ni, Lisong L; Guthrie, Sally K SK; Zubieta, Jon Kar JK
Publication Date: 2015-06-03

Variant appearance in text: rs9479757
PubMed Link: 25598501
Variant Present in the following documents:
  • Main text
  • nihms662335.pdf
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Clinical and genetic factors related to cancer-induced bone pain and bone pain relief.

The Oncologist
Scarpi, Emanuela E; Calistri, Daniele D; Klepstad, Pål P; Kaasa, Stein S; Skorpen, Frank F; Habberstad, Ragnhild R; Nanni, Oriana O; Amadori, Dino D; Maltoni, Marco M
Publication Date: 2014-12

Variant appearance in text: rs9479757
PubMed Link: 25342315
Variant Present in the following documents:
  • Main text
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A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
Xu, Jin J; Lu, Zhigang Z; Xu, Mingming M; Pan, Ling L; Deng, Yi Y; Xie, Xiaohu X; Liu, Huifen H; Ding, Shixiong S; Hurd, Yasmin L YL; Pasternak, Gavril W GW; Klein, Robert J RJ; Cartegni, Luca L; Zhou, Wenhua W; Pan, Ying-Xian YX
Publication Date: 2014-08-13

Variant appearance in text: rs9479757
PubMed Link: 25122903
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenetics of OPRM1.

Pharmacology, Biochemistry, And Behavior
Crist, Richard C RC; Berrettini, Wade H WH
Publication Date: 2014-08

Variant appearance in text: rs9479757
PubMed Link: 24201053
Variant Present in the following documents:
  • Main text
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Association of polymorphisms in pharmacogenetic candidate genes (OPRD1, GAL, ABCB1, OPRM1) with opioid dependence in European population: a case-control study.

Plos One
Beer, Beate B; Erb, Robert R; Pavlic, Marion M; Ulmer, Hanno H; Giacomuzzi, Salvatore S; Riemer, Yvonne Y; Oberacher, Herbert H
Publication Date: 2013

Variant appearance in text: rs9479757
PubMed Link: 24086514
Variant Present in the following documents:
  • Main text
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Gender, variation in opioid receptor genes and sensitivity to experimental pain.

Molecular Pain
Sato, Hiroe H; Droney, Joanne J; Ross, Joy J; Olesen, Anne Estrup AE; Staahl, Camilla C; Andresen, Trine T; Branford, Ruth R; Riley, Julia J; Arendt-Nielsen, Lars L; Drewes, Asbjørn Mohr AM
Publication Date: 2013-04-09

Variant appearance in text: rs9479757
PubMed Link: 23570317
Variant Present in the following documents:
  • Main text
  • 1744-8069-9-20.pdf
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Analgesia and central side-effects: two separate dimensions of morphine response.

British Journal Of Clinical Pharmacology
Droney, Joanne M JM; Gretton, Sophy K SK; Sato, Hiroe H; Ross, Joy R JR; Branford, Ruth R; Welsh, Kenneth I KI; Cookson, William W; Riley, Julia J
Publication Date: 2013-05

Variant appearance in text: rs9479757
PubMed Link: 23072578
Variant Present in the following documents:
  • Main text
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The genetics of the opioid system and specific drug addictions.

Human Genetics
Levran, Orna O; Yuferov, Vadim V; Kreek, Mary Jeanne MJ
Publication Date: 2012-06

Variant appearance in text: rs9479757
PubMed Link: 22547174
Variant Present in the following documents:
  • Main text
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Gender-stratified gene and gene-treatment interactions in smoking cessation.

The Pharmacogenomics Journal
Lee, W W; Bergen, A W AW; Swan, G E GE; Li, D D; Liu, J J; Thomas, P P; Tyndale, R F RF; Benowitz, N L NL; Lerman, C C; Conti, D V DV
Publication Date: 2012-12

Variant appearance in text: rs9479757
PubMed Link: 21808284
Variant Present in the following documents:
  • NIHMS305090-supplement-3.pdf
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The mu-opioid receptor gene and smoking initiation and nicotine dependence.

Behavioral And Brain Functions : Bbf
Zhang, Lan L; Kendler, Kenneth S KS; Chen, Xiangning X
Publication Date: 2006-08-04

Variant appearance in text: rs9479757
PubMed Link: 16887046
Variant Present in the following documents:
  • Main text
  • 1744-9081-2-28.pdf
View BVdb publication page