JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.
Cancer Research
Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K
Publication Date: 2022-11-21
Variant appearance in text: OPRM1: 644-83G>C; rs2075572
Introducing Precision Addiction Management of Reward Deficiency Syndrome, the Construct That Underpins All Addictive Behaviors.
Frontiers In Psychiatry
Blum, Kenneth K; Gondré-Lewis, Marjorie C MC; Baron, David D; Thanos, Panayotis K PK; Braverman, Eric R ER; Neary, Jennifer J; Elman, Igor I; Badgaiyan, Rajendra D RD
The AC/AG Diplotype for the 118A>G and IVS2 + 691G>C Polymorphisms of OPRM1 Gene is Associated with Sleep Quality Among Opioid-Dependent Patients on Methadone Maintenance Therapy.
Pain And Therapy
Zahari, Zalina Z; Lee, Chee Siong CS; Ibrahim, Muslih Abdulkarim MA; Musa, Nurfadhlina N; Mohd Yasin, Mohd Azhar MA; Lee, Yeong Yeh YY; Tan, Soo Choon SC; Mohamad, Nasir N; Ismail, Rusli R
The Opposing Roles of IVS2+691 CC Genotype and AC/AG Diplotype of 118A>G and IVS2+691G>C of OPRM1 Polymorphisms in Cold Pain Tolerance Among Opioid-Dependent Malay Males on Methadone Therapy.
Pain And Therapy
Zahari, Zalina Z; Lee, Chee Siong CS; Ibrahim, Muslih Abdulkarim MA; Musa, Nurfadhlina N; Yasin, Mohd Azhar Mohd MA; Lee, Yeong Yeh YY; Tan, Soo Choon SC; Mohamad, Nasir N; Ismail, Rusli R
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions.
The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
Xu, Jin J; Lu, Zhigang Z; Xu, Mingming M; Pan, Ling L; Deng, Yi Y; Xie, Xiaohu X; Liu, Huifen H; Ding, Shixiong S; Hurd, Yasmin L YL; Pasternak, Gavril W GW; Klein, Robert J RJ; Cartegni, Luca L; Zhou, Wenhua W; Pan, Ying-Xian YX
ELK1 transcription factor linked to dysregulated striatal mu opioid receptor signaling network and OPRM1 polymorphism in human heroin abusers.
Biological Psychiatry
Sillivan, Stephanie E SE; Whittard, John D JD; Jacobs, Michelle M MM; Ren, Yanhua Y; Mazloom, Amin R AR; Caputi, Francesca F FF; Horvath, Monika M; Keller, Eva E; Ma'ayan, Avi A; Pan, Ying-Xian YX; Chiang, Lillian W LW; Hurd, Yasmin L YL
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region.
Annals Of The Rheumatic Diseases
Peters, Marjolein J MJ; Broer, Linda L; Willemen, Hanneke L D M HL; Eiriksdottir, Gudny G; Hocking, Lynne J LJ; Holliday, Kate L KL; Horan, Michael A MA; Meulenbelt, Ingrid I; Neogi, Tuhina T; Popham, Maria M; Schmidt, Carsten O CO; Soni, Anushka A; Valdes, Ana M AM; Amin, Najaf N; Dennison, Elaine M EM; Eijkelkamp, Niels N; Harris, Tamara B TB; Hart, Deborah J DJ; Hofman, Albert A; Huygen, Frank J P M FJ; Jameson, Karen A KA; Jones, Gareth T GT; Launer, Lenore J LJ; Kerkhof, Hanneke J M HJ; de Kruijf, Marjolein M; McBeth, John J; Kloppenburg, Margreet M; Ollier, William E WE; Oostra, Ben B; Payton, Antony A; Rivadeneira, Fernando F; Smith, Blair H BH; Smith, Albert V AV; Stolk, Lisette L; Teumer, Alexander A; Thomson, Wendy W; Uitterlinden, André G AG; Wang, Ke K; van Wingerden, Sophie H SH; Arden, Nigel K NK; Cooper, Cyrus C; Felson, David D; Gudnason, Vilmundur V; Macfarlane, Gary J GJ; Pendleton, Neil N; Slagboom, P Eline PE; Spector, Tim D TD; Völzke, Henry H; Kavelaars, Annemieke A; van Duijn, Cornelia M CM; Williams, Frances M K FM; van Meurs, Joyce B J JB
Expansion of the human mu-opioid receptor gene architecture: novel functional variants.
Human Molecular Genetics
Shabalina, Svetlana A SA; Zaykin, Dmitri V DV; Gris, Pavel P; Ogurtsov, Aleksey Y AY; Gauthier, Josee J; Shibata, Kyoko K; Tchivileva, Inna E IE; Belfer, Inna I; Mishra, Bikashkumar B; Kiselycznyk, Carly C; Wallace, Margaret R MR; Staud, Roland R; Spiridonov, Nikolay A NA; Max, Mitchell B MB; Goldman, David D; Fillingim, Roger B RB; Maixner, William W; Diatchenko, Luda L
Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations in type 2 diabetes patients with nephropathy from an African-American population.
Human Genetics
Leak, Tennille S TS; Mychaleckyj, Josyf C JC; Smith, Shelly G SG; Keene, Keith L KL; Gordon, Candace J CJ; Hicks, Pamela J PJ; Freedman, Barry I BI; Bowden, Donald W DW; Sale, Michèle M MM
Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Luo, Xingguang X; Zuo, Lingjun L; Kranzler, Henry H; Zhang, Huiping H; Wang, Shuang S; Gelernter, Joel J