A Comprehensive Machine Learning Framework for the Exact Prediction of the Age of Onset in Familial and Sporadic Alzheimer's Disease.
Diagnostics (Basel, Switzerland)
Vélez, Jorge I JI; Samper, Luiggi A LA; Arcos-Holzinger, Mauricio M; Espinosa, Lady G LG; Isaza-Ruget, Mario A MA; Lopera, Francisco F; Arcos-Burgos, Mauricio M
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Emergent biomarker derived from next-generation sequencing to identify pain patients requiring uncommonly high opioid doses.
The Pharmacogenomics Journal
Kringel, D D; Ultsch, A A; Zimmermann, M M; Jansen, J-P JP; Ilias, W W; Freynhagen, R R; Griessinger, N N; Kopf, A A; Stein, C C; Doehring, A A; Resch, E E; Lötsch, J J
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.
Open Forum Infectious Diseases
Moore, Carrie B CB; Verma, Anurag A; Pendergrass, Sarah S; Verma, Shefali S SS; Johnson, Daniel H DH; Daar, Eric S ES; Gulick, Roy M RM; Haubrich, Richard R; Robbins, Gregory K GK; Ritchie, Marylyn D MD; Haas, David W DW
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
A non-synonymous single nucleotide polymorphism in an OPRM1 splice variant is associated with fentanyl-induced emesis in women undergoing minor gynaecological surgery.
Plos One
Pang, Grace Su Yin GS; Ithnin, Farida F; Wong, Yin Yee YY; Wang, Jing Bo JB; Lim, Yvonne Y; Sia, Alex Tiong Heng AT; Lee, Caroline Guat Lay CG
Expansion of the human mu-opioid receptor gene architecture: novel functional variants.
Human Molecular Genetics
Shabalina, Svetlana A SA; Zaykin, Dmitri V DV; Gris, Pavel P; Ogurtsov, Aleksey Y AY; Gauthier, Josee J; Shibata, Kyoko K; Tchivileva, Inna E IE; Belfer, Inna I; Mishra, Bikashkumar B; Kiselycznyk, Carly C; Wallace, Margaret R MR; Staud, Roland R; Spiridonov, Nikolay A NA; Max, Mitchell B MB; Goldman, David D; Fillingim, Roger B RB; Maixner, William W; Diatchenko, Luda L