Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma.
Nature Communications
North, Jeffrey P JP; Golovato, Justin J; Vaske, Charles J CJ; Sanborn, J Zachary JZ; Nguyen, Andrew A; Wu, Wei W; Goode, Benjamin B; Stevers, Meredith M; McMullen, Kevin K; Perez White, Bethany E BE; Collisson, Eric A EA; Bloomer, Michele M; Solomon, David A DA; Benz, Stephen C SC; Cho, Raymond J RJ
Genetic Association and Expression Analyses of the Phosphatidylinositol-4-Phosphate 5-Kinase (PIP5K1C) Gene in Alcohol Use Disorder-Relevance for Pain Signaling and Alcohol Use.
Alcoholism, Clinical And Experimental Research
Lee, Ji Soo JS; Sorcher, Jill L JL; Rosen, Allison D AD; Damadzic, Ruslan R; Sun, Hui H; Schwandt, Melanie M; Heilig, Markus M; Kelly, John J; Mauro, Kelsey L KL; Luo, Audrey A; Rosoff, Daniel D; Muench, Christine C; Jung, Jeesun J; Kaminsky, Zachary A ZA; Lohoff, Falk W FW
Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.
Bmc Cancer
Lonjou, Christine C; Damiola, Francesca F; Moissonnier, Monika M; Durand, Geoffroy G; Malakhova, Irina I; Masyakin, Vladimir V; Le Calvez-Kelm, Florence F; Cardis, Elisabeth E; Byrnes, Graham G; Kesminiene, Ausrele A; Lesueur, Fabienne F
Emergent biomarker derived from next-generation sequencing to identify pain patients requiring uncommonly high opioid doses.
The Pharmacogenomics Journal
Kringel, D D; Ultsch, A A; Zimmermann, M M; Jansen, J-P JP; Ilias, W W; Freynhagen, R R; Griessinger, N N; Kopf, A A; Stein, C C; Doehring, A A; Resch, E E; Lötsch, J J
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Dimensionality and Genetic Correlates of Problem Behavior in Low-Income African American Adolescents.
Journal Of Clinical Child And Adolescent Psychology : The Official Journal For The Society Of Clinical Child And Adolescent Psychology, American Psychological Association, Division 53
Latendresse, Shawn J SJ; Henry, David B DB; Aggen, Steven H SH; Byck, Gayle R GR; Ashbeck, Alan W AW; Bolland, John M JM; Sun, Cuie C; Riley, Brien P BP; Mustanski, Brian B; Dick, Danielle M DM
Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1.
Biological Psychiatry
Hancock, Dana B DB; Levy, Joshua L JL; Gaddis, Nathan C NC; Glasheen, Cristie C; Saccone, Nancy L NL; Page, Grier P GP; Hulse, Gary K GK; Wildenauer, Dieter D; Kelty, Erin A EA; Schwab, Sibylle G SG; Degenhardt, Louisa L; Martin, Nicholas G NG; Montgomery, Grant W GW; Attia, John J; Holliday, Elizabeth G EG; McEvoy, Mark M; Scott, Rodney J RJ; Bierut, Laura J LJ; Nelson, Elliot C EC; Kral, Alex H AH; Johnson, Eric O EO
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
A non-synonymous single nucleotide polymorphism in an OPRM1 splice variant is associated with fentanyl-induced emesis in women undergoing minor gynaecological surgery.
Plos One
Pang, Grace Su Yin GS; Ithnin, Farida F; Wong, Yin Yee YY; Wang, Jing Bo JB; Lim, Yvonne Y; Sia, Alex Tiong Heng AT; Lee, Caroline Guat Lay CG
Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder.
The American Journal Of Psychiatry
Garriock, Holly A HA; Tanowitz, Michael M; Kraft, Jeffrey B JB; Dang, Vu C VC; Peters, Eric J EJ; Jenkins, Greg D GD; Reinalda, Megan S MS; McGrath, Patrick J PJ; von Zastrow, Mark M; Slager, Susan L SL; Hamilton, Steven P SP