SLC22A1 c.181C>A ;(p.R61S)

Variant ID: 6-160543148-C-A

NM_003057.2(SLC22A1):c.181C>A;(p.R61S)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Pharmacogenetics of hepatocellular carcinoma and cholangiocarcinoma.

Cancer Drug Resistance (Alhambra, Calif.)
Alonso-Peña, Marta M; Sanchez-Martin, Anabel A; Sanchon-Sanchez, Paula P; Soto-Muñiz, Meraris M; Espinosa-Escudero, Ricardo R; Marin, Jose J G JJG
Publication Date: 2019

Variant appearance in text: SLC22A1: Arg61Ser
PubMed Link: 35582588
Variant Present in the following documents:
  • Main text
  • cdr-2-680.pdf
View BVdb publication page



Genetic Heterogeneity, Therapeutic Hurdle Confronting Sorafenib and Immune Checkpoint Inhibitors in Hepatocellular Carcinoma.

Cancers
Atwa, Sara M SM; Odenthal, Margarete M; M El Tayebi, Hend H
Publication Date: 2021-08-27

Variant appearance in text: SLC22A1: R61S
PubMed Link: 34503153
Variant Present in the following documents:
  • Main text
  • cancers-13-04343.pdf
View BVdb publication page



Genetic Heterogeneity, Therapeutic Hurdle Confronting Sorafenib and Immune Checkpoint Inhibitors in Hepatocellular Carcinoma.

Cancers
Atwa, Sara M SM; Odenthal, Margarete M; El Tayebi, Hend M HM
Publication Date: 2021-08-27

Variant appearance in text: SLC22A1: R61S
PubMed Link: 34503153
Variant Present in the following documents:
  • Main text
  • cancers-13-04343.pdf
View BVdb publication page



Sorafenib Resistance in Hepatocellular Carcinoma: The Relevance of Genetic Heterogeneity.

Cancers
Cabral, Loraine Kay D LKD; Tiribelli, Claudio C; Sukowati, Caecilia H C CHC
Publication Date: 2020-06-15

Variant appearance in text: SLC22A1: R61S
PubMed Link: 32549224
Variant Present in the following documents:
  • Main text
  • cancers-12-01576.pdf
View BVdb publication page



Role of OCT1 in hepatocellular carcinoma.

Oncotargets And Therapy
Li, Jingguo J; Yang, Zhengyi Z; Tuo, Biguang B
Publication Date: 2019

Variant appearance in text: SLC22A1: R61S
PubMed Link: 31413596
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenetics of the systemic treatment in advanced hepatocellular carcinoma.

World Journal Of Gastroenterology
De Mattia, Elena E; Cecchin, Erika E; Guardascione, Michela M; Foltran, Luisa L; Di Raimo, Tania T; Angelini, Francesco F; D'Andrea, Mario M; Toffoli, Giuseppe G
Publication Date: 2019-08-07

Variant appearance in text: SLC22A1: Arg61Ser
PubMed Link: 31413525
Variant Present in the following documents:
  • Main text
  • WJG-25-3870.pdf
View BVdb publication page



Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.

Journal Of Personalized Medicine
Lozano, Elisa E; Briz, Oscar O; Macias, Rocio I R RIR; Serrano, Maria A MA; Marin, Jose J G JJG; Herraez, Elisa E
Publication Date: 2018-04-16

Variant appearance in text: SLC22A1: R61S
PubMed Link: 29659532
Variant Present in the following documents:
  • Main text
  • jpm-08-00014.pdf
View BVdb publication page



The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma.

Oncotarget
Geier, Andreas A; Macias, Rocio I R RI; Bettinger, Dominik D; Weiss, Johannes J; Bantel, Heike H; Jahn, Daniel D; Al-Abdulla, Ruba R; Marin, Jose J G JJ
Publication Date: 2017-02-28

Variant appearance in text: SLC22A1: R61S
PubMed Link: 28178663
Variant Present in the following documents:
  • Main text
  • oncotarget-08-15846.pdf
View BVdb publication page



Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacology.

Biomed Research International
Lozano, Elisa E; Herraez, Elisa E; Briz, Oscar O; Robledo, Virginia S VS; Hernandez-Iglesias, Jorge J; Gonzalez-Hernandez, Ana A; Marin, Jose J G JJ
Publication Date: 2013

Variant appearance in text: SLC22A1: R61S
PubMed Link: 23984399
Variant Present in the following documents:
  • Main text
  • BMRI2013-692071.pdf
View BVdb publication page