SLC22A1 c.1025G>A ;(p.R342H)

Variant ID: 6-160557646-G-A

NM_003057.2(SLC22A1):c.1025G>A;(p.R342H)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Publication Date: 2023-03-16

Variant appearance in text: SLC22A1: R342H
PubMed Link: 36928921
Variant Present in the following documents:
  • ccr-22-3642_supplementary_tables_1_suppts1.xlsx, sheet 3
View BVdb publication page



Genetic variants in African-American and Hispanic patients with breast cancer.

Oncology Letters
Dutta, Pranabananda P; Keung, Man Y MY; Wu, Yanyuan Y; Vadgama, Jaydutt V JV
Publication Date: 2023-02

Variant appearance in text: SLC22A1: 1025G>A; R342H
PubMed Link: 36644153
Variant Present in the following documents:
  • Supplementary_Data5.xlsx, sheet 1
View BVdb publication page



Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment.

Antimicrobial Agents And Chemotherapy
Pernaute-Lau, Leyre L; Adegnika, Ayola Akim AA; Zhou, Yitian Y; Zinsou, Jeannot F JF; Gil, Jose Pedro JP; Krishna, Sanjeev S; Kremsner, Peter G PG; Lauschke, Volker M VM; Velavan, Thirumalaisamy P TP
Publication Date: 2021-06-17

Variant appearance in text: SLC22A1: R342H
PubMed Link: 33875422
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics of Medication-Induced Weight Gain and Antiobesity Medications.

Obesity (Silver Spring, Md.)
Singh, Sneha S; Ricardo-Silgado, Maria L ML; Bielinski, Suzette J SJ; Acosta, Andres A
Publication Date: 2021-02

Variant appearance in text: rs34205214
PubMed Link: 33491309
Variant Present in the following documents:
  • Main text
View BVdb publication page



The genetic landscape of the human solute carrier (SLC) transporter superfamily.

Human Genetics
Schaller, Lena L; Lauschke, Volker M VM
Publication Date: 2019-12

Variant appearance in text: SLC22A1: R342H
PubMed Link: 31679053
Variant Present in the following documents:
  • 439_2019_Article_2081.pdf
View BVdb publication page



Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers.

Cell Reports
Cheng, Hui H; Yang, Xinping X; Si, Han H; Saleh, Anthony D AD; Xiao, Wenming W; Coupar, Jamie J; Gollin, Susanne M SM; Ferris, Robert L RL; Issaeva, Natalia N; Yarbrough, Wendell G WG; Prince, Mark E ME; Carey, Thomas E TE; Van Waes, Carter C; Chen, Zhong Z
Publication Date: 2018-10-30

Variant appearance in text: SLC22A1: R342H; rs34205214
PubMed Link: 30380422
Variant Present in the following documents:
  • NIHMS1511993-supplement-6.xlsx, sheet 1
View BVdb publication page



Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.

Nature Genetics
Zhao, Wei W; Rasheed, Asif A; Tikkanen, Emmi E; Lee, Jung-Jin JJ; Butterworth, Adam S AS; Howson, Joanna M M JMM; Assimes, Themistocles L TL; Chowdhury, Rajiv R; Orho-Melander, Marju M; Damrauer, Scott S; Small, Aeron A; Asma, Senay S; Imamura, Minako M; Yamauch, Toshimasa T; Chambers, John C JC; Chen, Peng P; Sapkota, Bishwa R BR; Shah, Nabi N; Jabeen, Sehrish S; Surendran, Praveen P; Lu, Yingchang Y; Zhang, Weihua W; Imran, Atif A; Abbas, Shahid S; Majeed, Faisal F; Trindade, Kevin K; Qamar, Nadeem N; Mallick, Nadeem Hayyat NH; Yaqoob, Zia Z; Saghir, Tahir T; Rizvi, Syed Nadeem Hasan SNH; Memon, Anis A; Rasheed, Syed Zahed SZ; Memon, Fazal-Ur-Rehman FU; Mehmood, Khalid K; Ahmed, Naveeduddin N; Qureshi, Irshad Hussain IH; Tanveer-Us-Salam, ; Iqbal, Wasim W; Malik, Uzma U; Mehra, Narinder N; Kuo, Jane Z JZ; Sheu, Wayne H-H WH; Guo, Xiuqing X; Hsiung, Chao A CA; Juang, Jyh-Ming J JJ; Taylor, Kent D KD; Hung, Yi-Jen YJ; Lee, Wen-Jane WJ; Quertermous, Thomas T; Lee, I-Te IT; Hsu, Chih-Cheng CC; Bottinger, Erwin P EP; Ralhan, Sarju S; Teo, Yik Ying YY; Wang, Tzung-Dau TD; Alam, Dewan S DS; Di Angelantonio, Emanuele E; Epstein, Steve S; Nielsen, Sune F SF; Nordestgaard, Børge G BG; Tybjaerg-Hansen, Anne A; Young, Robin R; , ; Benn, Marianne M; Frikke-Schmidt, Ruth R; Kamstrup, Pia R PR; , ; , ; , ; Jukema, J Wouter JW; Sattar, Naveed N; Smit, Roelof R; Chung, Ren-Hua RH; Liang, Kae-Woei KW; Anand, Sonia S; Sanghera, Dharambir K DK; Ripatti, Samuli S; Loos, Ruth J F RJF; Kooner, Jaspal S JS; Tai, E Shyong ES; Rotter, Jerome I JI; Chen, Yii-Der Ida YI; Frossard, Philippe P; Maeda, Shiro S; Kadowaki, Takashi T; Reilly, Muredach M; Pare, Guillaume G; Melander, Olle O; Salomaa, Veikko V; Rader, Daniel J DJ; Danesh, John J; Voight, Benjamin F BF; Saleheen, Danish D
Publication Date: 2017-10

Variant appearance in text: SLC22A1: R342H
PubMed Link: 28869590
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effects of SLC22A1 Polymorphisms on Metformin-Induced Reductions in Adiposity and Metformin Pharmacokinetics in Obese Children With Insulin Resistance.

Journal Of Clinical Pharmacology
Sam, Wai Johnn WJ; Roza, Orsolya O; Hon, Yuen Yi YY; Alfaro, Raul M RM; Calis, Karim A KA; Reynolds, James C JC; Yanovski, Jack A JA
Publication Date: 2017-02

Variant appearance in text: SLC22A1: Arg342His; rs34205214
PubMed Link: 27407018
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.

Oncogene
Nickerson, M L ML; Witte, N N; Im, K M KM; Turan, S S; Owens, C C; Misner, K K; Tsang, S X SX; Cai, Z Z; Wu, S S; Dean, M M; Costello, J C JC; Theodorescu, D D
Publication Date: 2017-01-05

Variant appearance in text: SLC22A1: R342H; rs34205214
PubMed Link: 27270441
Variant Present in the following documents:
  • onc2016172x3.xls, sheet 3
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs34205214
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics
Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J
Publication Date: 2015-07-25

Variant appearance in text: SLC22A1: R342H
PubMed Link: 26206375
Variant Present in the following documents:
  • 12859_2015_673_MOESM1_ESM.xls, sheet 4
View BVdb publication page



Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1.

Genome Medicine
Seitz, Tina T; Stalmann, Robert R; Dalila, Nawar N; Chen, Jiayin J; Pojar, Sherin S; Dos Santos Pereira, Joao N JN; Krätzner, Ralph R; Brockmöller, Jürgen J; Tzvetkov, Mladen V MV
Publication Date: 2015

Variant appearance in text: SLC22A1: Arg342His
PubMed Link: 26157489
Variant Present in the following documents:
  • Main text
  • 13073_2015_Article_172.pdf
View BVdb publication page



Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacology.

Biomed Research International
Lozano, Elisa E; Herraez, Elisa E; Briz, Oscar O; Robledo, Virginia S VS; Hernandez-Iglesias, Jorge J; Gonzalez-Hernandez, Ana A; Marin, Jose J G JJ
Publication Date: 2013

Variant appearance in text: SLC22A1: 1025G>A; R342H; rs34205214
PubMed Link: 23984399
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics in type II diabetes mellitus management: Steps toward personalized medicine.

Pharmacogenomics And Personalized Medicine
Avery, Peter P; Mousa, Shaymaa S SS; Mousa, Shaker A SA
Publication Date: 2009

Variant appearance in text: SLC22A1: R342H
PubMed Link: 23226037
Variant Present in the following documents:
  • Main text
  • pgpm-2-079.pdf
View BVdb publication page