SLC22A2 c.596C>T ;(p.T199I)

Variant ID: 6-160671657-G-A

NM_003058.3(SLC22A2):c.596C>T;(p.T199I)

This variant was identified in 22 publications

View GRCh38 version.




Publications:


Genetic polymorphism related to ethambutol outcomes and susceptibility to toxicity.

Frontiers In Genetics
Barliana, Melisa Intan MI; Afifah, Nadiya Nurul NN; Yunivita, Vycke V; Ruslami, Rovina R
Publication Date: 2023

Variant appearance in text: rs201919874
PubMed Link: 37152993
Variant Present in the following documents:
  • Main text
  • fgene-14-1118102.pdf
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A Review of the Impact of Pharmacogenetics and Metabolomics on the Efficacy of Metformin in Type 2 Diabetes.

International Journal Of Medical Sciences
Damanhouri, Zoheir A ZA; Alkreathy, Huda M HM; Alharbi, Fawaz A FA; Abualhamail, Haneen H; Ahmad, Muhammad S MS
Publication Date: 2023

Variant appearance in text: rs201919874
PubMed Link: 36619226
Variant Present in the following documents:
  • ijmsv20p0142.pdf
View BVdb publication page



Determinants in Tailoring Antidiabetic Therapies: A Personalized Approach.

Global Medical Genetics
Rizvi, Aliya A AA; Abbas, Mohammad M; Verma, Sushma S; Verma, Shrikant S; Khan, Almas A; Raza, Syed T ST; Mahdi, Farzana F
Publication Date: 2022-06

Variant appearance in text: rs201919874
PubMed Link: 35707783
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenetics of Type 2 Diabetes-Progress and Prospects.

International Journal Of Molecular Sciences
Nasykhova, Yulia A YA; Tonyan, Ziravard N ZN; Mikhailova, Anastasiia A AA; Danilova, Maria M MM; Glotov, Andrey S AS
Publication Date: 2020-09-18

Variant appearance in text: SLC22A2: T199I; rs201919874
PubMed Link: 32961860
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomic Studies of Current Antidiabetic Agents and Potential New Drug Targets for Precision Medicine of Diabetes.

Diabetes Therapy : Research, Treatment And Education Of Diabetes And Related Disorders
Zeng, Zhiwei Z; Huang, Shi-Ying SY; Sun, Tao T
Publication Date: 2020-11

Variant appearance in text: rs201919874
PubMed Link: 32930968
Variant Present in the following documents:
  • Main text
  • 13300_2020_Article_922.pdf
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The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition.

International Journal Of Molecular Sciences
Zazuli, Zulfan Z; Duin, Naut J C B NJCB; Jansen, Katja K; Vijverberg, Susanne J H SJH; Maitland-van der Zee, Anke H AH; Masereeuw, Rosalinde R
Publication Date: 2020-09-10

Variant appearance in text: SLC22A2: T199I; rs201919874
PubMed Link: 32927790
Variant Present in the following documents:
  • Main text
View BVdb publication page



Metformin Pharmacogenetics: Effects of SLC22A1, SLC22A2, and SLC22A3 Polymorphisms on Glycemic Control and HbA1c Levels.

Journal Of Personalized Medicine
Al-Eitan, Laith N LN; Almomani, Basima A BA; Nassar, Ahmad M AM; Elsaqa, Barakat Z BZ; Saadeh, Nesreen A NA
Publication Date: 2019-03-25

Variant appearance in text: SLC22A2: T199I
PubMed Link: 30934600
Variant Present in the following documents:
  • Main text
  • jpm-09-00017.pdf
View BVdb publication page



Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine.

Diabetes/Metabolism Research And Reviews
Mannino, Gaia Chiara GC; Andreozzi, Francesco F; Sesti, Giorgio G
Publication Date: 2019-03

Variant appearance in text: SLC22A2: Thr199Ile; rs201919874
PubMed Link: 30515958
Variant Present in the following documents:
  • Main text
  • DMRR-35-na.pdf
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An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

The Pharmacogenomics Journal
Zhou, Yitian Y; Mkrtchian, Souren S; Kumondai, Masaki M; Hiratsuka, Masahiro M; Lauschke, Volker M VM
Publication Date: 2019-04

Variant appearance in text: SLC22A2: T199I; rs201919874
PubMed Link: 30206299
Variant Present in the following documents:
  • 41397_2018_44_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.

Journal Of Personalized Medicine
Lozano, Elisa E; Briz, Oscar O; Macias, Rocio I R RIR; Serrano, Maria A MA; Marin, Jose J G JJG; Herraez, Elisa E
Publication Date: 2018-04-16

Variant appearance in text: SLC22A2: T199I
PubMed Link: 29659532
Variant Present in the following documents:
  • Main text
  • jpm-08-00014.pdf
View BVdb publication page



Precision medicine in diabetes prevention, classification and management.

Journal Of Diabetes Investigation
Xie, Fangying F; Chan, Juliana Cn JC; Ma, Ronald Cw RC
Publication Date: 2018-09

Variant appearance in text: SLC22A2: 596C>T; rs201919874
PubMed Link: 29499103
Variant Present in the following documents:
  • Main text
  • JDI-9-998.pdf
View BVdb publication page



Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics
Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR
Publication Date: 2017-03

Variant appearance in text: rs201919874
PubMed Link: 27984508
Variant Present in the following documents:
  • fpc-27-089-s005.xlsx, sheet 2
View BVdb publication page



Pharmacogenetic studies update in type 2 diabetes mellitus.

World Journal Of Diabetes
Singh, Shalini S; Usman, Kauser K; Banerjee, Monisha M
Publication Date: 2016-08-10

Variant appearance in text: SLC22A2: T199I; rs201919874
PubMed Link: 27555891
Variant Present in the following documents:
  • Main text
View BVdb publication page



Personalized medicine in Type 2 Diabetes.

Biomedicine
Liao, Wen-Ling WL; Tsai, Fuu-Jen FJ
Publication Date: 2014

Variant appearance in text: rs201919874
PubMed Link: 25520921
Variant Present in the following documents:
  • Main text
  • 40681_2014_Article_8.pdf
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An update on the pharmacogenomics of metformin: progress, problems and potential.

Pharmacogenomics
Todd, Jennifer N JN; Florez, Jose C JC
Publication Date: 2014-03

Variant appearance in text: SLC22A2: T199I
PubMed Link: 24624919
Variant Present in the following documents:
  • Main text
View BVdb publication page



Membrane transporters as mediators of Cisplatin effects and side effects.

Scientifica
Ciarimboli, Giuliano G
Publication Date: 2012

Variant appearance in text: SLC22A2: T199I
PubMed Link: 24278698
Variant Present in the following documents:
  • SCIENTIFICA2012-473829.pdf
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Unraveling the genetic basis of aspirin hypersensitivity in asthma beyond arachidonate pathways.

Allergy, Asthma & Immunology Research
Park, Se-Min SM; Park, Jong Sook JS; Park, Hae-Sim HS; Park, Choon-Sik CS
Publication Date: 2013-09

Variant appearance in text: SLC22A2: Thr199Ile
PubMed Link: 24003382
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenetics and personalized treatment of type 2 diabetes.

Biochemia Medica
Semiz, Sabina S; Dujic, Tanja T; Causevic, Adlija A
Publication Date: 2013

Variant appearance in text: SLC22A2: Thr199Ile; rs201919874
PubMed Link: 23894862
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy.

Pharmacogenomics And Personalized Medicine
Li, Jing J; Bluth, Martin H MH
Publication Date: 2011

Variant appearance in text: SLC22A2: T199I
PubMed Link: 23226051
Variant Present in the following documents:
  • Main text
  • pgpm-4-011.pdf
View BVdb publication page



Metformin pathways: pharmacokinetics and pharmacodynamics.

Pharmacogenetics And Genomics
Gong, Li L; Goswami, Srijib S; Giacomini, Kathleen M KM; Altman, Russ B RB; Klein, Teri E TE
Publication Date: 2012-11

Variant appearance in text: SLC22A2: 596C>T
PubMed Link: 22722338
Variant Present in the following documents:
  • Main text
View BVdb publication page



SLC22A2 gene 808 G/T variant is related to plasma lactate concentration in Chinese type 2 diabetics treated with metformin.

Acta Pharmacologica Sinica
Li, Qing Q; Liu, Fang F; Zheng, Tai-shan TS; Tang, Jun-ling JL; Lu, Hui-juan HJ; Jia, Wei-ping WP
Publication Date: 2010-02

Variant appearance in text: SLC22A2: T199I
PubMed Link: 20139901
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study.

Diabetes
Becker, Matthijs L ML; Visser, Loes E LE; van Schaik, Ron H N RH; Hofman, Albert A; Uitterlinden, André G AG; Stricker, Bruno H Ch BH
Publication Date: 2009-03

Variant appearance in text: SLC22A2: T199I
PubMed Link: 19228809
Variant Present in the following documents:
  • Main text
  • 745.pdf
View BVdb publication page