Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.
Cell Reports. Medicine
Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools.
Plos One
Sebate, Boiketlo B; Cuttler, Katelyn K; Cloete, Ruben R; Britz, Marcell M; Christoffels, Alan A; Williams, Monique M; Carr, Jonathan J; Bardien, Soraya S
Publication Date: 2021
Variant appearance in text: PLG: 1414G>A; D472N; rs4252125
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Publication Date: 2021-01-08
Variant appearance in text: PLG: 1414G>A; D472N; rs4252125
Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy.
Cell
Krug, Karsten K; Jaehnig, Eric J EJ; Satpathy, Shankha S; Blumenberg, Lili L; Karpova, Alla A; Anurag, Meenakshi M; Miles, George G; Mertins, Philipp P; Geffen, Yifat Y; Tang, Lauren C LC; Heiman, David I DI; Cao, Song S; Maruvka, Yosef E YE; Lei, Jonathan T JT; Huang, Chen C; Kothadia, Ramani B RB; Colaprico, Antonio A; Birger, Chet C; Wang, Jarey J; Dou, Yongchao Y; Wen, Bo B; Shi, Zhiao Z; Liao, Yuxing Y; Wiznerowicz, Maciej M; Wyczalkowski, Matthew A MA; Chen, Xi Steven XS; Kennedy, Jacob J JJ; Paulovich, Amanda G AG; Thiagarajan, Mathangi M; Kinsinger, Christopher R CR; Hiltke, Tara T; Boja, Emily S ES; Mesri, Mehdi M; Robles, Ana I AI; Rodriguez, Henry H; Westbrook, Thomas F TF; Ding, Li L; Getz, Gad G; Clauser, Karl R KR; Fenyö, David D; Ruggles, Kelly V KV; Zhang, Bing B; Mani, D R DR; Carr, Steven A SA; Ellis, Matthew J MJ; Gillette, Michael A MA; ,
Multi-omic studies on missense PLG variants in families with otitis media.
Scientific Reports
Bootpetch, Tori C TC; Hafrén, Lena L; Elling, Christina L CL; Baschal, Erin E EE; Manichaikul, Ani W AW; Pine, Harold S HS; Szeremeta, Wasyl W; Scholes, Melissa A MA; Cass, Stephen P SP; Larson, Eric D ED; Chan, Kenny H KH; Ishaq, Rafaqat R; Prager, Jeremy D JD; Shaikh, Rehan S RS; Gubbels, Samuel P SP; Yousaf, Ayesha A; , ; Wine, Todd M TM; Bamshad, Michael J MJ; Yoon, Patricia J PJ; Jenkins, Herman A HA; Nickerson, Deborah A DA; Streubel, Sven-Olrik SO; Friedman, Norman R NR; Frank, Daniel N DN; Einarsdottir, Elisabet E; Kere, Juha J; Riazuddin, Saima S; Daly, Kathleen A KA; Leal, Suzanne M SM; Ryan, Allen F AF; Mattila, Petri S PS; Ahmed, Zubair M ZM; Sale, Michele M MM; Chonmaitree, Tasnee T; Santos-Cortez, Regie Lyn P RLP
Publication Date: 2020-09-14
Variant appearance in text: PLG: Asp472Asn; rs4252125
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Scientific Reports
Stringer, Brett W BW; Day, Bryan W BW; D'Souza, Rochelle C J RCJ; Jamieson, Paul R PR; Ensbey, Kathleen S KS; Bruce, Zara C ZC; Lim, Yi Chieh YC; Goasdoué, Kate K; Offenhäuser, Carolin C; Akgül, Seçkin S; Allan, Suzanne S; Robertson, Thomas T; Lucas, Peter P; Tollesson, Gert G; Campbell, Scott S; Winter, Craig C; Do, Hongdo H; Dobrovic, Alexander A; Inglis, Po-Ling PL; Jeffree, Rosalind L RL; Johns, Terrance G TG; Boyd, Andrew W AW
Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.
Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
X-linked ADGRG2 mutation and obstructive azoospermia in a large Pakistani family.
Scientific Reports
Khan, Muhammad Jaseem MJ; Pollock, Nijole N; Jiang, Huaiyang H; Castro, Carlos C; Nazli, Rubina R; Ahmed, Jawad J; Basit, Sulman S; Rajkovic, Aleksandar A; Yatsenko, Alexander N AN
Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia.
Genome Research
Bhattacharya, Sanchita S; Li, Jian J; Sockell, Alexandra A; Kan, Matthew J MJ; Bava, Felice A FA; Chen, Shann-Ching SC; Ávila-Arcos, María C MC; Ji, Xuhuai X; Smith, Emery E; Asadi, Narges B NB; Lachman, Ralph S RS; Lam, Hugo Y K HYK; Bustamante, Carlos D CD; Butte, Atul J AJ; Nolan, Garry P GP
A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.
Journal Of Lipid Research
Mack, Salome S; Coassin, Stefan S; Rueedi, Rico R; Yousri, Noha A NA; Seppälä, Ilkka I; Gieger, Christian C; Schönherr, Sebastian S; Forer, Lukas L; Erhart, Gertraud G; Marques-Vidal, Pedro P; Ried, Janina S JS; Waeber, Gerard G; Bergmann, Sven S; Dähnhardt, Doreen D; Stöckl, Andrea A; Raitakari, Olli T OT; Kähönen, Mika M; Peters, Annette A; Meitinger, Thomas T; Strauch, Konstantin K; , ; Kedenko, Ludmilla L; Paulweber, Bernhard B; Lehtimäki, Terho T; Hunt, Steven C SC; Vollenweider, Peter P; Lamina, Claudia C; Kronenberg, Florian F
Publication Date: 2017-09
Variant appearance in text: PLG: Asp472Asn; rs4252125
A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.
Journal Of Lipid Research
Mack, Salome S; Coassin, Stefan S; Rueedi, Rico R; Yousri, Noha A NA; Seppälä, Ilkka I; Gieger, Christian C; Schönherr, Sebastian S; Forer, Lukas L; Erhart, Gertraud G; Marques-Vidal, Pedro P; Ried, Janina S JS; Waeber, Gerard G; Bergmann, Sven S; Dähnhardt, Doreen D; Stöckl, Andrea A; Raitakari, Olli T OT; Kähönen, Mika M; Peters, Annette A; Meitinger, Thomas T; Strauch, Konstantin K; Kedenko, Ludmilla L; Paulweber, Bernhard B; Lehtimäki, Terho T; Hunt, Steven C SC; Vollenweider, Peter P; Lamina, Claudia C; Kronenberg, Florian F
Publication Date: 2017-09
Variant appearance in text: PLG: Asp472Asn; rs4252125
Validation of single nucleotide polymorphisms in invasive aspergillosis following hematopoietic cell transplantation.
Blood
Fisher, Cynthia E CE; Hohl, Tobias M TM; Fan, Wenhong W; Storer, Barry E BE; Levine, David M DM; Zhao, Lu Ping LP; Martin, Paul J PJ; Warren, Edus H EH; Boeckh, Michael M; Hansen, John A JA
A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis.
American Journal Of Human Genetics
Carmona, F David FD; Vaglio, Augusto A; Mackie, Sarah L SL; Hernández-Rodríguez, José J; Monach, Paul A PA; Castañeda, Santos S; Solans, Roser R; Morado, Inmaculada C IC; Narváez, Javier J; Ramentol-Sintas, Marc M; Pease, Colin T CT; Dasgupta, Bhaskar B; Watts, Richard R; Khalidi, Nader N; Langford, Carol A CA; Ytterberg, Steven S; Boiardi, Luigi L; Beretta, Lorenzo L; Govoni, Marcello M; Emmi, Giacomo G; Bonatti, Francesco F; Cimmino, Marco A MA; Witte, Torsten T; Neumann, Thomas T; Holle, Julia J; Schönau, Verena V; Sailler, Laurent L; Papo, Thomas T; Haroche, Julien J; Mahr, Alfred A; Mouthon, Luc L; Molberg, Øyvind Ø; Diamantopoulos, Andreas P AP; Voskuyl, Alexandre A; Brouwer, Elisabeth E; Daikeler, Thomas T; Berger, Christoph T CT; Molloy, Eamonn S ES; O'Neill, Lorraine L; Blockmans, Daniel D; Lie, Benedicte A BA; Mclaren, Paul P; Vyse, Timothy J TJ; Wijmenga, Cisca C; Allanore, Yannick Y; Koeleman, Bobby P C BPC; , ; , ; , ; Barrett, Jennifer H JH; Cid, María C MC; Salvarani, Carlo C; Merkel, Peter A PA; Morgan, Ann W AW; González-Gay, Miguel A MA; Martín, Javier J
Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model.
The Journal Of Pathology
Maguire, Sarah L SL; Peck, Barrie B; Wai, Patty T PT; Campbell, James J; Barker, Holly H; Gulati, Aditi A; Daley, Frances F; Vyse, Simon S; Huang, Paul P; Lord, Christopher J CJ; Farnie, Gillian G; Brennan, Keith K; Natrajan, Rachael R
Miller, Clint L CL; Pjanic, Milos M; Wang, Ting T; Nguyen, Trieu T; Cohain, Ariella A; Lee, Jonathan D JD; Perisic, Ljubica L; Hedin, Ulf U; Kundu, Ramendra K RK; Majmudar, Deshna D; Kim, Juyong B JB; Wang, Oliver O; Betsholtz, Christer C; Ruusalepp, Arno A; Franzén, Oscar O; Assimes, Themistocles L TL; Montgomery, Stephen B SB; Schadt, Eric E EE; Björkegren, Johan L M JLM; Quertermous, Thomas T
Proteogenomics connects somatic mutations to signalling in breast cancer.
Nature
Mertins, Philipp P; Mani, D R DR; Ruggles, Kelly V KV; Gillette, Michael A MA; Clauser, Karl R KR; Wang, Pei P; Wang, Xianlong X; Qiao, Jana W JW; Cao, Song S; Petralia, Francesca F; Kawaler, Emily E; Mundt, Filip F; Krug, Karsten K; Tu, Zhidong Z; Lei, Jonathan T JT; Gatza, Michael L ML; Wilkerson, Matthew M; Perou, Charles M CM; Yellapantula, Venkata V; Huang, Kuan-lin KL; Lin, Chenwei C; McLellan, Michael D MD; Yan, Ping P; Davies, Sherri R SR; Townsend, R Reid RR; Skates, Steven J SJ; Wang, Jing J; Zhang, Bing B; Kinsinger, Christopher R CR; Mesri, Mehdi M; Rodriguez, Henry H; Ding, Li L; Paulovich, Amanda G AG; Fenyö, David D; Ellis, Matthew J MJ; Carr, Steven A SA; ,
Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients.
G3 (Bethesda, Md.)
Sadovnick, A Dessa AD; Traboulsee, Anthony L AL; Bernales, Cecily Q CQ; Ross, Jay P JP; Forwell, Amanda L AL; Yee, Irene M IM; Guillot-Noel, Lena L; Fontaine, Bertrand B; Cournu-Rebeix, Isabelle I; Alcina, Antonio A; Fedetz, Maria M; Izquierdo, Guillermo G; Matesanz, Fuencisla F; Hilven, Kelly K; Dubois, Bénédicte B; Goris, An A; Astobiza, Ianire I; Alloza, Iraide I; Antigüedad, Alfredo A; Vandenbroeck, Koen K; Akkad, Denis A DA; Aktas, Orhan O; Blaschke, Paul P; Buttmann, Mathias M; Chan, Andrew A; Epplen, Joerg T JT; Gerdes, Lisa-Ann LA; Kroner, Antje A; Kubisch, Christian C; Kümpfel, Tania T; Lohse, Peter P; Rieckmann, Peter P; Zettl, Uwe K UK; Zipp, Frauke F; Bertram, Lars L; Lill, Christina M CM; Fernandez, Oscar O; Urbaneja, Patricia P; Leyva, Laura L; Alvarez-Cermeño, Jose Carlos JC; Arroyo, Rafael R; Garagorri, Aroa M AM; García-Martínez, Angel A; Villar, Luisa M LM; Urcelay, Elena E; Malhotra, Sunny S; Montalban, Xavier X; Comabella, Manuel M; Berger, Thomas T; Fazekas, Franz F; Reindl, Markus M; Schmied, Mascha C MC; Zimprich, Alexander A; Vilariño-Güell, Carles C
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver.
The Pharmacogenomics Journal
Schröder, A A; Klein, K K; Winter, S S; Schwab, M M; Bonin, M M; Zell, A A; Zanger, U M UM
Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.
Journal Of Lipid Research
Ober, Carole C; Nord, Alex S AS; Thompson, Emma E EE; Pan, Lin L; Tan, Zheng Z; Cusanovich, Darren D; Sun, Ying Y; Nicolae, Raluca R; Edelstein, Celina C; Schneider, Daniel H DH; Billstrand, Christine C; Pfaffinger, Ditta D; Phillips, Natasha N; Anderson, Rebecca L RL; Philips, Binu B; Rajagopalan, Ramakrishnan R; Hatsukami, Thomas S TS; Rieder, Mark J MJ; Heagerty, Patrick J PJ; Nickerson, Deborah A DA; Abney, Mark M; Marcovina, Santica S; Jarvik, Gail P GP; Scanu, Angelo M AM; Nicolae, Dan L DL
Plasminogen alleles influence susceptibility to invasive aspergillosis.
Plos Genetics
Zaas, Aimee K AK; Liao, Guochun G; Chien, Jason W JW; Weinberg, Clarice C; Shore, David D; Giles, Steven S SS; Marr, Kieren A KA; Usuka, Jonathan J; Burch, Lauranell H LH; Perera, Lalith L; Perfect, John R JR; Peltz, Gary G; Schwartz, David A DA
Publication Date: 2008-06-20
Variant appearance in text: PLG: Asp472Asn; rs4252125