Replication of associations between genetic polymorphisms and chronic graft-versus-host disease.
Blood
Martin, Paul J PJ; Fan, Wenhong W; Storer, Barry E BE; Levine, David M DM; Zhao, Lue Ping LP; Warren, Edus H EH; Flowers, Mary E D ME; Lee, Stephanie J SJ; Carpenter, Paul A PA; Boeckh, Michael M; Hingorani, Sangeeta S; Yan, Li L; Hu, Qiang Q; Preus, Leah L; Liu, Song S; Spellman, Stephen S; Zhu, Xiaochun X; Pasquini, Marcelo M; McCarthy, Philip P; Stram, Daniel D; Sheng, Xin X; Pooler, Loreall L; Haiman, Christopher A CA; Sucheston-Campbell, Lara L; Hahn, Theresa T; Hansen, John A JA
Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells.
Cell
Koues, Olivia I OI; Collins, Patrick L PL; Cella, Marina M; Robinette, Michelle L ML; Porter, Sofia I SI; Pyfrom, Sarah C SC; Payton, Jacqueline E JE; Colonna, Marco M; Oltz, Eugene M EM
Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls.
Carcinogenesis
Kang, Xiaozheng X; Liu, Hongliang H; Onaitis, Mark W MW; Liu, Zhensheng Z; Owzar, Kouros K; Han, Younghun Y; Su, Li L; Wei, Yongyue Y; Hung, Rayjean J RJ; Brhane, Yonathan Y; McLaughlin, John J; Brennan, Paul P; Bickeböller, Heike H; Rosenberger, Albert A; Houlston, Richard S RS; Caporaso, Neil N; Landi, Maria Teresa MT; Heinrich, Joachim J; Risch, Angela A; Wu, Xifeng X; Ye, Yuanqing Y; Christiani, David C DC; Amos, Christopher I CI; Wei, Qingyi Q; ,
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
Nature Genetics
Kiryluk, Krzysztof K; Li, Yifu Y; Scolari, Francesco F; Sanna-Cherchi, Simone S; Choi, Murim M; Verbitsky, Miguel M; Fasel, David D; Lata, Sneh S; Prakash, Sindhuri S; Shapiro, Samantha S; Fischman, Clara C; Snyder, Holly J HJ; Appel, Gerald G; Izzi, Claudia C; Viola, Battista Fabio BF; Dallera, Nadia N; Del Vecchio, Lucia L; Barlassina, Cristina C; Salvi, Erika E; Bertinetto, Francesca Eleonora FE; Amoroso, Antonio A; Savoldi, Silvana S; Rocchietti, Marcella M; Amore, Alessandro A; Peruzzi, Licia L; Coppo, Rosanna R; Salvadori, Maurizio M; Ravani, Pietro P; Magistroni, Riccardo R; Ghiggeri, Gian Marco GM; Caridi, Gianluca G; Bodria, Monica M; Lugani, Francesca F; Allegri, Landino L; Delsante, Marco M; Maiorana, Mariarosa M; Magnano, Andrea A; Frasca, Giovanni G; Boer, Emanuela E; Boscutti, Giuliano G; Ponticelli, Claudio C; Mignani, Renzo R; Marcantoni, Carmelita C; Di Landro, Domenico D; Santoro, Domenico D; Pani, Antonello A; Polci, Rosaria R; Feriozzi, Sandro S; Chicca, Silvana S; Galliani, Marco M; Gigante, Maddalena M; Gesualdo, Loreto L; Zamboli, Pasquale P; Battaglia, Giovanni Giorgio GG; Garozzo, Maurizio M; Maixnerová, Dita D; Tesar, Vladimir V; Eitner, Frank F; Rauen, Thomas T; Floege, Jürgen J; Kovacs, Tibor T; Nagy, Judit J; Mucha, Krzysztof K; Pączek, Leszek L; Zaniew, Marcin M; Mizerska-Wasiak, Małgorzata M; Roszkowska-Blaim, Maria M; Pawlaczyk, Krzysztof K; Gale, Daniel D; Barratt, Jonathan J; Thibaudin, Lise L; Berthoux, Francois F; Canaud, Guillaume G; Boland, Anne A; Metzger, Marie M; Panzer, Ulf U; Suzuki, Hitoshi H; Goto, Shin S; Narita, Ichiei I; Caliskan, Yasar Y; Xie, Jingyuan J; Hou, Ping P; Chen, Nan N; Zhang, Hong H; Wyatt, Robert J RJ; Novak, Jan J; Julian, Bruce A BA; Feehally, John J; Stengel, Benedicte B; Cusi, Daniele D; Lifton, Richard P RP; Gharavi, Ali G AG
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits.
Genome Research
Corradin, Olivia O; Saiakhova, Alina A; Akhtar-Zaidi, Batool B; Myeroff, Lois L; Willis, Joseph J; Cowper-Sal lari, Richard R; Lupien, Mathieu M; Markowitz, Sanford S; Scacheri, Peter C PC
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Seven newly identified loci for autoimmune thyroid disease.
Human Molecular Genetics
Cooper, Jason D JD; Simmonds, Matthew J MJ; Walker, Neil M NM; Burren, Oliver O; Brand, Oliver J OJ; Guo, Hui H; Wallace, Chris C; Stevens, Helen H; Coleman, Gillian G; , ; Franklyn, Jayne A JA; Todd, John A JA; Gough, Stephen C L SC
DNase I sensitivity QTLs are a major determinant of human expression variation.
Nature
Degner, Jacob F JF; Pai, Athma A AA; Pique-Regi, Roger R; Veyrieras, Jean-Baptiste JB; Gaffney, Daniel J DJ; Pickrell, Joseph K JK; De Leon, Sherryl S; Michelini, Katelyn K; Lewellen, Noah N; Crawford, Gregory E GE; Stephens, Matthew M; Gilad, Yoav Y; Pritchard, Jonathan K JK
Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis.
Inflammatory Bowel Diseases
Waterman, Matti M; Xu, Wei W; Stempak, Joanne M JM; Milgrom, Raquel R; Bernstein, Charles N CN; Griffiths, Anne M AM; Greenberg, Gordon R GR; Steinhart, A Hillary AH; Silverberg, Mark S MS
Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease.
Plos Genetics
Danoy, Patrick P; Pryce, Karena K; Hadler, Johanna J; Bradbury, Linda A LA; Farrar, Claire C; Pointon, Jennifer J; , ; Ward, Michael M; Weisman, Michael M; Reveille, John D JD; Wordsworth, B Paul BP; Stone, Millicent A MA; , ; Maksymowych, Walter P WP; Rahman, Proton P; Gladman, Dafna D; Inman, Robert D RD; Brown, Matthew A MA
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.
Human Molecular Genetics
McGovern, Dermot P B DP; Jones, Michelle R MR; Taylor, Kent D KD; Marciante, Kristin K; Yan, Xiaofei X; Dubinsky, Marla M; Ippoliti, Andy A; Vasiliauskas, Eric E; Berel, Dror D; Derkowski, Carrie C; Dutridge, Deb D; Fleshner, Phil P; Shih, David Q DQ; Melmed, Gil G; Mengesha, Emebet E; King, Lily L; Pressman, Sheila S; Haritunians, Talin T; Guo, Xiuqing X; Targan, Stephan R SR; Rotter, Jerome I JI; ,
Common variants in FOXP1 are associated with generalized vitiligo.
Nature Genetics
Jin, Ying Y; Birlea, Stanca A SA; Fain, Pamela R PR; Mailloux, Christina M CM; Riccardi, Sheri L SL; Gowan, Katherine K; Holland, Paulene J PJ; Bennett, Dorothy C DC; Wallace, Margaret R MR; McCormack, Wayne T WT; Kemp, E Helen EH; Gawkrodger, David J DJ; Weetman, Anthony P AP; Picardo, Mauro M; Leone, Giovanni G; Taïeb, Alain A; Jouary, Thomas T; Ezzedine, Khaled K; van Geel, Nanny N; Lambert, Jo J; Overbeck, Andreas A; Spritz, Richard A RA
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
Nature Genetics
Stahl, Eli A EA; Raychaudhuri, Soumya S; Remmers, Elaine F EF; Xie, Gang G; Eyre, Stephen S; Thomson, Brian P BP; Li, Yonghong Y; Kurreeman, Fina A S FA; Zhernakova, Alexandra A; Hinks, Anne A; Guiducci, Candace C; Chen, Robert R; Alfredsson, Lars L; Amos, Christopher I CI; Ardlie, Kristin G KG; , ; Barton, Anne A; Bowes, John J; Brouwer, Elisabeth E; Burtt, Noel P NP; Catanese, Joseph J JJ; Coblyn, Jonathan J; Coenen, Marieke J H MJ; Costenbader, Karen H KH; Criswell, Lindsey A LA; Crusius, J Bart A JB; Cui, Jing J; de Bakker, Paul I W PI; De Jager, Philip L PL; Ding, Bo B; Emery, Paul P; Flynn, Edward E; Harrison, Pille P; Hocking, Lynne J LJ; Huizinga, Tom W J TW; Kastner, Daniel L DL; Ke, Xiayi X; Lee, Annette T AT; Liu, Xiangdong X; Martin, Paul P; Morgan, Ann W AW; Padyukov, Leonid L; Posthumus, Marcel D MD; Radstake, Timothy R D J TR; Reid, David M DM; Seielstad, Mark M; Seldin, Michael F MF; Shadick, Nancy A NA; Steer, Sophia S; Tak, Paul P PP; Thomson, Wendy W; van der Helm-van Mil, Annette H M AH; van der Horst-Bruinsma, Irene E IE; van der Schoot, C Ellen CE; van Riel, Piet L C M PL; Weinblatt, Michael E ME; Wilson, Anthony G AG; Wolbink, Gert Jan GJ; Wordsworth, B Paul BP; , ; Wijmenga, Cisca C; Karlson, Elizabeth W EW; Toes, Rene E M RE; de Vries, Niek N; Begovich, Ann B AB; Worthington, Jane J; Siminovitch, Katherine A KA; Gregersen, Peter K PK; Klareskog, Lars L; Plenge, Robert M RM
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.
Nature
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Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
Nature Genetics
McGovern, Dermot P B DP; Gardet, Agnès A; Törkvist, Leif L; Goyette, Philippe P; Essers, Jonah J; Taylor, Kent D KD; Neale, Benjamin M BM; Ong, Rick T H RT; Lagacé, Caroline C; Li, Chun C; Green, Todd T; Stevens, Christine R CR; Beauchamp, Claudine C; Fleshner, Phillip R PR; Carlson, Marie M; D'Amato, Mauro M; Halfvarson, Jonas J; Hibberd, Martin L ML; Lördal, Mikael M; Padyukov, Leonid L; Andriulli, Angelo A; Colombo, Elisabetta E; Latiano, Anna A; Palmieri, Orazio O; Bernard, Edmond-Jean EJ; Deslandres, Colette C; Hommes, Daan W DW; de Jong, Dirk J DJ; Stokkers, Pieter C PC; Weersma, Rinse K RK; , ; Sharma, Yashoda Y; Silverberg, Mark S MS; Cho, Judy H JH; Wu, Jing J; Roeder, Kathryn K; Brant, Steven R SR; Schumm, L Phillip LP; Duerr, Richard H RH; Dubinsky, Marla C MC; Glazer, Nicole L NL; Haritunians, Talin T; Ippoliti, Andy A; Melmed, Gil Y GY; Siscovick, David S DS; Vasiliauskas, Eric A EA; Targan, Stephan R SR; Annese, Vito V; Wijmenga, Cisca C; Pettersson, Sven S; Rotter, Jerome I JI; Xavier, Ramnik J RJ; Daly, Mark J MJ; Rioux, John D JD; Seielstad, Mark M
Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data.
Bmc Proceedings
Deshmukh, Harshal H; Kim-Howard, Xana X; Nath, Swapan K SK
Origins and functional impact of copy number variation in the human genome.
Nature
Conrad, Donald F DF; Pinto, Dalila D; Redon, Richard R; Feuk, Lars L; Gokcumen, Omer O; Zhang, Yujun Y; Aerts, Jan J; Andrews, T Daniel TD; Barnes, Chris C; Campbell, Peter P; Fitzgerald, Tomas T; Hu, Min M; Ihm, Chun Hwa CH; Kristiansson, Kati K; Macarthur, Daniel G DG; Macdonald, Jeffrey R JR; Onyiah, Ifejinelo I; Pang, Andy Wing Chun AW; Robson, Sam S; Stirrups, Kathy K; Valsesia, Armand A; Walter, Klaudia K; Wei, John J; , ; Tyler-Smith, Chris C; Carter, Nigel P NP; Lee, Charles C; Scherer, Stephen W SW; Hurles, Matthew E ME
Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
Plos Genetics
Raychaudhuri, Soumya S; Plenge, Robert M RM; Rossin, Elizabeth J EJ; Ng, Aylwin C Y AC; , ; Purcell, Shaun M SM; Sklar, Pamela P; Scolnick, Edward M EM; Xavier, Ramnik J RJ; Altshuler, David D; Daly, Mark J MJ
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
Nature Genetics
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