Impact of Variants in the ATIC and ARID5B Genes on Therapeutic Failure with Imatinib in Patients with Chronic Myeloid Leukemia.
Genes
Cereja Pantoja, Karla Beatriz Cardias KBC; Azevedo, Tereza Cristina de Brito TCB; Carvalho, Darlen Cardoso de DC; Monte, Natasha N; Cohen Paes, Amanda de Nazaré AN; Barros, Maria Clara da Costa MCDC; Vinagre, Lui Wallacy Morikawa Souza LWMS; Freitas, Ana Rosa Sales de ARS; Burbano, Rommel Mario Rodríguez RMR; Assumpção, Paulo Pimentel de PP; Santos, Sidney Emanuel Batista Dos SEBD; Fernandes, Marianne Rodrigues MR; Santos, Ney Pereira Carneiro Dos NPCD
A next-generation sequencing-based strategy combining microsatellite instability and tumor mutation burden for comprehensive molecular diagnosis of advanced colorectal cancer.
Association of candidate pharmacogenetic markers with platinum-induced ototoxicity: PanCareLIFE dataset.
Data In Brief
Langer, Thorsten T; Clemens, Eva E; Broer, Linda L; Maier, Lara L; Uitterlinden, André G AG; de Vries, Andrica C H ACH; van Grotel, Martine M; Pluijm, Saskia F M SFM; Binder, Harald H; Mayer, Benjamin B; von dem Knesebeck, Annika A; Byrne, Julianne J; van Dulmen-den Broeder, Eline E; Crocco, Marco M; Grabow, Desiree D; Kaatsch, Peter P; Kaiser, Melanie M; Spix, Claudia C; Kenborg, Line L; Winther, Jeanette F JF; Rechnitzer, Catherine C; Hasle, Henrik H; Kepak, Tomas T; van der Kooi, Anne-Lotte F AF; Kremer, Leontien C LC; Kruseova, Jarmila J; Bielack, Stefan S; Sorg, Benjamin B; Hecker-Nolting, Stefanie S; Kuehni, Claudia E CE; Ansari, Marc M; Kompis, Martin M; van der Pal, Heleen J HJ; Parfitt, Ross R; Deuster, Dirk D; Matulat, Peter P; Tillmanns, Amelie A; Tissing, Wim J E WJE; Beck, Jörn D JD; Elsner, Susanne S; Am Zehnhoff-Dinnesen, Antoinette A; van den Heuvel-Eibrink, Marry M MM; Zolk, Oliver O; ,
Assessment and Management of Platinum-Related Ototoxicity in Children Treated for Cancer.
Cancers
Romano, Alberto A; Capozza, Michele Antonio MA; Mastrangelo, Stefano S; Maurizi, Palma P; Triarico, Silvia S; Rolesi, Rolando R; Attinà, Giorgio G; Fetoni, Anna Rita AR; Ruggiero, Antonio A
MTHFR and VDR Polymorphisms Improve the Prognostic Value of MYCN Status on Overall Survival in Neuroblastoma Patients.
International Journal Of Molecular Sciences
Olivera, Gladys G GG; Yáñez, Yania Y; Gargallo, Pablo P; Sendra, Luis L; Aliño, Salvador F SF; Segura, Vanessa V; Sanz, Miguel Ángel MÁ; Cañete, Adela A; Castel, Victoria V; Font De Mora, Jaime J; Hervás, David D; Berlanga, Pablo P; Herrero, María José MJ
Genetic Variants as Predictive Markers for Ototoxicity and Nephrotoxicity in Patients with Locally Advanced Head and Neck Cancer Treated with Cisplatin-Containing Chemoradiotherapy (The PRONE Study).
Cancers
Driessen, Chantal M CM; Ham, Janneke C JC; Te Loo, Maroeska M; van Meerten, Esther E; van Lamoen, Maurits M; Hakobjan, Marina H MH; Takes, Robert P RP; van der Graaf, Winette T WT; Kaanders, Johannes H JH; Coenen, Marieke J H MJH; van Herpen, Carla M CM
The genetic vulnerability to cisplatin ototoxicity: a systematic review.
Scientific Reports
Tserga, Evangelia E; Nandwani, Tara T; Edvall, Niklas K NK; Bulla, Jan J; Patel, Poulam P; Canlon, Barbara B; Cederroth, Christopher R CR; Baguley, David M DM
Analytical Validation of Variants to Aid in Genotype-Guided Therapy for Oncology.
The Journal Of Molecular Diagnostics : Jmd
Swart, Marelize M; Stansberry, Wesley M WM; Pratt, Victoria M VM; Medeiros, Elizabeth B EB; Kiel, Patrick J PJ; Shen, Fei F; Schneider, Bryan P BP; Skaar, Todd C TC
Publication Date: 2019-05
Variant appearance in text: TPMT: 419+94T>A; rs12201199
TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity.
Pharmacogenetics And Genomics
Thiesen, Signe S; Yin, Peng P; Jorgensen, Andrea L AL; Zhang, Jieying Eunice JE; Manzo, Valentina V; McEvoy, Laurence L; Barton, Christopher C; Picton, Susan S; Bailey, Simon S; Brock, Penelope P; Vyas, Harish H; Walker, David D; Makin, Guy G; Bandi, Srinivas S; Pizer, Barry B; Hawcutt, Daniel B DB; Pirmohamed, Munir M
Pharmacogenomics in Pediatric Patients: Towards Personalized Medicine.
Paediatric Drugs
Maagdenberg, Hedy H; Vijverberg, Susanne J H SJ; Bierings, Marc B MB; Carleton, Bruce C BC; Arets, Hubertus G M HG; de Boer, Anthonius A; Maitland-van der Zee, Anke H AH
Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity.
Pharmacogenomics
Lanvers-Kaminsky, Claudia C; Sprowl, Jason A JA; Malath, Ingrid I; Deuster, Dirk D; Eveslage, Maria M; Schlatter, Eberhard E; Mathijssen, Ron Hj RH; Boos, Joachim J; Jürgens, Heribert H; Am Zehnhoff-Dinnesen, Antionette G AG; Sparreboom, Alex A; Ciarimboli, Giuliano G
Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.
Plos One
Hagleitner, Melanie M MM; Coenen, Marieke J H MJ; Patino-Garcia, Ana A; de Bont, Eveline S J M ES; Gonzalez-Neira, Anna A; Vos, Hanneke I HI; van Leeuwen, Frank N FN; Gelderblom, Hans H; Hoogerbrugge, Peter M PM; Guchelaar, Henk-Jan HJ; Te Loo, Maroeska W M MW
Screening for 392 polymorphisms in 141 pharmacogenes.
Biomedical Reports
Kim, Jason Yongha JY; Cheong, Hyun Sub HS; Park, Tae-Joon TJ; Shin, Hee Jung HJ; Seo, Doo Won DW; Na, Han Sung HS; Chung, Myeon Woo MW; Shin, Hyoung Doo HD
Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.
Pharmacogenomics
Matimba, Alice A; Li, Fang F; Livshits, Alina A; Cartwright, Cher S CS; Scully, Stephen S; Fridley, Brooke L BL; Jenkins, Gregory G; Batzler, Anthony A; Wang, Liewei L; Weinshilboum, Richard R; Lennard, Lynne L
Chemotherapy-induced peripheral neurotoxicity and ototoxicity: new paradigms for translational genomics.
Journal Of The National Cancer Institute
Travis, Lois B LB; Fossa, Sophie D SD; Sesso, Howard D HD; Frisina, Robert D RD; Herrmann, David N DN; Beard, Clair J CJ; Feldman, Darren R DR; Pagliaro, Lance C LC; Miller, Robert C RC; Vaughn, David J DJ; Einhorn, Lawrence H LH; Cox, Nancy J NJ; Dolan, M Eileen ME; ,
The role of inherited TPMT and COMT genetic variation in cisplatin-induced ototoxicity in children with cancer.
Clinical Pharmacology And Therapeutics
Yang, J J JJ; Lim, J Y S JY; Huang, J J; Bass, J J; Wu, J J; Wang, C C; Fang, J J; Stewart, E E; Harstead, E H EH; E, S S; Robinson, G W GW; Evans, W E WE; Pappo, A A; Zuo, J J; Relling, M V MV; Onar-Thomas, A A; Gajjar, A A; Stewart, C F CF
Replication of TPMT and ABCC3 genetic variants highly associated with cisplatin-induced hearing loss in children.
Clinical Pharmacology And Therapeutics
Pussegoda, K K; Ross, C J CJ; Visscher, H H; Yazdanpanah, M M; Brooks, B B; Rassekh, S R SR; Zada, Y F YF; Dubé, M-P MP; Carleton, B C BC; Hayden, M R MR; ,
Chemotherapy refractory testicular germ cell tumor is associated with a variant in Armadillo Repeat gene deleted in Velco-Cardio-Facial syndrome (ARVCF).
Frontiers In Endocrinology
Fung, Chunkit C; Vaughn, David J DJ; Mitra, Nandita N; Ciosek, Stephanie L SL; Vardhanabhuti, Saran S; Nathanson, Katherine L KL; Kanetsky, Peter A PA
Platinum-induced ototoxicity in children: a consensus review on mechanisms, predisposition, and protection, including a new International Society of Pediatric Oncology Boston ototoxicity scale.
Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Brock, Penelope R PR; Knight, Kristin R KR; Freyer, David R DR; Campbell, Kathleen C M KC; Steyger, Peter S PS; Blakley, Brian W BW; Rassekh, Shahrad R SR; Chang, Kay W KW; Fligor, Brian J BJ; Rajput, Kaukab K; Sullivan, Michael M; Neuwelt, Edward A EA
Role of genetic susceptibility in development of treatment-related adverse outcomes in cancer survivors.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology