Development and validation of a multivariable genotype-informed gestational diabetes prediction algorithm for clinical use in the Mexican population: insights into susceptibility mechanisms.
Bmj Open Diabetes Research & Care
Zulueta, Mirella M; Gallardo-Rincón, Héctor H; Martinez-Juarez, Luis Alberto LA; Lomelin-Gascon, Julieta J; Ortega-Montiel, Janinne J; Montoya, Alejandra A; Mendizabal, Leire L; Arregi, Maddi M; Martinez-Martinez, María de Los Angeles MLA; Camarillo Romero, Eneida Del Socorro EDS; Mendieta Zerón, Hugo H; Garduño García, José de Jesús JJ; Simón, Laureano L; Tapia-Conyer, Roberto R
The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population.
Diabetologia
Wedekind, Lauren E LE; Mahajan, Anubha A; Hsueh, Wen-Chi WC; Chen, Peng P; Olaiya, Muideen T MT; Kobes, Sayuko S; Sinha, Madhumita M; Baier, Leslie J LJ; Knowler, William C WC; McCarthy, Mark I MI; Hanson, Robert L RL
Genetic variants for prediction of gestational diabetes mellitus and modulation of susceptibility by a nutritional intervention based on a Mediterranean diet.
Frontiers In Endocrinology
Ramos-Levi, Ana A; Barabash, Ana A; Valerio, Johanna J; García de la Torre, Nuria N; Mendizabal, Leire L; Zulueta, Mirella M; de Miguel, Maria Paz MP; Diaz, Angel A; Duran, Alejandra A; Familiar, Cristina C; Jimenez, Inés I; Del Valle, Laura L; Melero, Veronica V; Moraga, Inmaculada I; Herraiz, Miguel A MA; Torrejon, María José MJ; Arregi, Maddi M; Simón, Laureano L; Rubio, Miguel A MA; Calle-Pascual, Alfonso L AL
CDKAL1 gene rs7756992 A/G and rs7754840 G/C polymorphisms are associated with gestational diabetes mellitus in a sample of Bangladeshi population: implication for future T2DM prophylaxis.
Diabetology & Metabolic Syndrome
Amin, U S Mahzabin USM; Parvez, Nahid N; Rahman, Tahia Anan TA; Hasan, Md Rakibul MR; Das, Keshob Chandra KC; Jahan, Sharmin S; Hasanat, Muhammad Abul MA; Seraj, Zeba I ZI; Salimullah, Md M
CDKAL1 gene rs7756992 A/G and rs7754840 G/C polymorphisms are associated with gestational diabetes mellitus in a sample of Bangladeshi population: implication for future T2DM prophylaxis.
Diabetology & Metabolic Syndrome
Amin, U S Mahzabin USM; Parvez, Nahid N; Rahman, Tahia Anan TA; Hasan, Md Rakibul MR; Das, Keshob Chandra KC; Jahan, Sharmin S; Hasanat, Muhammad Abul MA; Seraj, Zeba I ZI; Salimullah, Md M
Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis.
Journal Of The National Cancer Institute
Murphy, Neil N; Song, Mingyang M; Papadimitriou, Nikos N; Carreras-Torres, Robert R; Langenberg, Claudia C; Martin, Richard M RM; Tsilidis, Konstantinos K KK; Barroso, Inês I; Chen, Ji J; Frayling, Timothy M TM; Bull, Caroline J CJ; Vincent, Emma E EE; Cotterchio, Michelle M; Gruber, Stephen B SB; Pai, Rish K RK; Newcomb, Polly A PA; Perez-Cornago, Aurora A; van Duijnhoven, Franzel J B FJB; Van Guelpen, Bethany B; Vodicka, Pavel P; Wolk, Alicja A; Wu, Anna H AH; Peters, Ulrike U; Chan, Andrew T AT; Gunter, Marc J MJ
Consanguinity and Diabetes in Saudi Population: A Case-Control Study.
Cureus
Alzahrani, Saad H SH; Alzahrani, Nawaf M NM; Al Jabir, Fahad M FM; Alsharef, Mohammed K MK; Zaheer, Shawana S; Hussein, Salma H SH; Alguwaihes, Abdullah M AM; Jammah, Anwar A AA
Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus.
Bmc Medical Genomics
Prasad, Rashmi B RB; Kristensen, Karl K; Katsarou, Anastasia A; Shaat, Nael N
Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus.
Bmc Medical Genomics
Prasad, Rashmi B RB; Kristensen, Karl K; Katsarou, Anastasia A; Shaat, Nael N
CDK5 Regulatory Subunit-Associated Protein 1-Like 1 Gene Polymorphisms and Gestational Diabetes Mellitus Risk: A Trial Sequential Meta-Analysis of 13,306 Subjects.
Pharmacogenetic association of diabetes-associated genetic risk score with rapid progression of coronary artery calcification following treatment with HMG-CoA-reductase inhibitors -results of the Heinz Nixdorf Recall Study.
Naunyn-Schmiedeberg'S Archives Of Pharmacology
Pechlivanis, Sonali S; Jung, Dominik D; Moebus, Susanne S; Lehmann, Nils N; Mahabadi, Amir A AA; Hoffmann, Per P; Erbel, Raimund R; Nöthen, Markus M MM; Bachmann, Hagen S HS
PheMap: a multi-resource knowledge base for high-throughput phenotyping within electronic health records.
Journal Of The American Medical Informatics Association : Jamia
Zheng, Neil S NS; Feng, QiPing Q; Kerchberger, V Eric VE; Zhao, Juan J; Edwards, Todd L TL; Cox, Nancy J NJ; Stein, C Michael CM; Roden, Dan M DM; Denny, Joshua C JC; Wei, Wei-Qi WQ
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity.
The Journal Of Clinical Endocrinology And Metabolism
Deshmukh, Harshal A HA; Madsen, Anne Lundager AL; Viñuela, Ana A; Have, Christian Theil CT; Grarup, Niels N; Tura, Andrea A; Mahajan, Anubha A; Heggie, Alison J AJ; Koivula, Robert W RW; De Masi, Federico F; Tsirigos, Konstantinos K KK; Linneberg, Allan A; Drivsholm, Thomas T; Pedersen, Oluf O; Sørensen, Thorkild I A TIA; Astrup, Arne A; Gjesing, Anette A P AAP; Pavo, Imre I; Wood, Andrew R AR; Ruetten, Hartmut H; Jones, Angus G AG; Koopman, Anitra D M ADM; Cederberg, Henna H; Rutters, Femke F; Ridderstrale, Martin M; Laakso, Markku M; McCarthy, Mark I MI; Frayling, Tim M TM; Ferrannini, Ele E; Franks, Paul W PW; Pearson, Ewan R ER; Mari, Andrea A; Hansen, Torben T; Walker, Mark M
Obesity, clinical, and genetic predictors for glycemic progression in Chinese patients with type 2 diabetes: A cohort study using the Hong Kong Diabetes Register and Hong Kong Diabetes Biobank.
Plos Medicine
Jiang, Guozhi G; Luk, Andrea O AO; Tam, Claudia H T CHT; Lau, Eric S ES; Ozaki, Risa R; Chow, Elaine Y K EYK; Kong, Alice P S APS; Lim, Cadmon K P CKP; Lee, Ka Fai KF; Siu, Shing Chung SC; Hui, Grace G; Tsang, Chiu Chi CC; Lau, Kam Piu KP; Leung, Jenny Y Y JYY; Tsang, Man-Wo MW; Kam, Grace G; Lau, Ip Tim IT; Li, June K JK; Yeung, Vincent T VT; Lau, Emmy E; Lo, Stanley S; Fung, Samuel K S SKS; Cheng, Yuk Lun YL; Chow, Chun Chung CC; Pearson, Ewan R ER; So, Wing Yee WY; Chan, Juliana C N JCN; Ma, Ronald C W RCW; , ; ,
Pharmacogenetics of hypoglycemia associated with sulfonylurea therapy in usual clinical care.
The Pharmacogenomics Journal
Mitchell, Sabrina L SL; Leon, Daniel A Carranza DAC; Chaugai, Sandip S; Kawai, Vivian K VK; Levinson, Rebecca T RT; Wei, Wei-Qi WQ; Stein, C Michael CM
The impact of phenotype, ethnicity and genotype on progression of type 2 diabetes mellitus.
Endocrinology, Diabetes & Metabolism
Thakarakkattil Narayanan Nair, Anand A; Donnelly, Louise A LA; Dawed, Adem Y AY; Gan, Sushrima S; Anjana, Ranjit M RM; Viswanathan, Mohan M; Palmer, Colin N A CNA; Pearson, Ewan R ER
Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations.
Bmj Open Diabetes Research & Care
Li, Mengying M; Rahman, Mohammad L ML; Wu, Jing J; Ding, Ming M; Chavarro, Jorge E JE; Lin, Yuan Y; Ley, Sylvia H SH; Bao, Wei W; Grunnet, Louise G LG; Hinkle, Stefanie N SN; Thuesen, Anne Cathrine B ACB; Yeung, Edwina E; Gore-Langton, Robert E RE; Sherman, Seth S; Hjort, Line L; Kampmann, Freja Bach FB; Bjerregaard, Anne Ahrendt AA; Damm, Peter P; Tekola-Ayele, Fasil F; Liu, Aiyi A; Mills, James L JL; Vaag, Allan A; Olsen, Sjurdur F SF; Hu, Frank B FB; Zhang, Cuilin C
Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis.
Bmj (Clinical Research Ed.)
Merino, Jordi J; Guasch-Ferré, Marta M; Ellervik, Christina C; Dashti, Hassan S HS; Sharp, Stephen J SJ; Wu, Peitao P; Overvad, Kim K; Sarnowski, Chloé C; Kuokkanen, Mikko M; Lemaitre, Rozenn N RN; Justice, Anne E AE; Ericson, Ulrika U; Braun, Kim V E KVE; Mahendran, Yuvaraj Y; Frazier-Wood, Alexis C AC; Sun, Dianjianyi D; Chu, Audrey Y AY; Tanaka, Toshiko T; Luan, Jian'an J; Hong, Jaeyoung J; Tjønneland, Anne A; Ding, Ming M; Lundqvist, Annamari A; Mukamal, Kenneth K; Rohde, Rebecca R; Schulz, Christina-Alexandra CA; Franco, Oscar H OH; Grarup, Niels N; Chen, Yii-Der Ida YI; Bazzano, Lydia L; Franks, Paul W PW; Buring, Julie E JE; Langenberg, Claudia C; Liu, Ching-Ti CT; Hansen, Torben T; Jensen, Majken K MK; Sääksjärvi, Katri K; Psaty, Bruce M BM; Young, Kristin L KL; Hindy, George G; Sandholt, Camilla Helene CH; Ridker, Paul M PM; Ordovas, Jose M JM; Meigs, James B JB; Pedersen, Oluf O; Kraft, Peter P; Perola, Markus M; North, Kari E KE; Orho-Melander, Marju M; Voortman, Trudy T; Toft, Ulla U; Rotter, Jerome I JI; Qi, Lu L; Forouhi, Nita G NG; Mozaffarian, Dariush D; Sørensen, Thorkild I A TIA; Stampfer, Meir J MJ; Männistö, Satu S; Selvin, Elizabeth E; Imamura, Fumiaki F; Salomaa, Veikko V; Hu, Frank B FB; Wareham, Nick J NJ; Dupuis, Josée J; Smith, Caren E CE; Kilpeläinen, Tuomas O TO; Chasman, Daniel I DI; Florez, Jose C JC
Genes for Good: Engaging the Public in Genetics Research via Social Media.
American Journal Of Human Genetics
Brieger, Katharine K; Zajac, Gregory J M GJM; Pandit, Anita A; Foerster, Johanna R JR; Li, Kevin W KW; Annis, Aubrey C AC; Schmidt, Ellen M EM; Clark, Chris P CP; McMorrow, Karly K; Zhou, Wei W; Yang, Jingjing J; Kwong, Alan M AM; Boughton, Andrew P AP; Wu, Jinxi J; Scheller, Chris C; Parikh, Tanvi T; de la Vega, Alejandro A; Brazel, David M DM; Frieser, Maia M; Rea-Sandin, Gianna G; Fritsche, Lars G LG; Vrieze, Scott I SI; Abecasis, Gonçalo R GR
Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.
Scientific Reports
Christodoulou, Maria-Ioanna MI; Avgeris, Margaritis M; Kokkinopoulou, Ioanna I; Maratou, Eirini E; Mitrou, Panayota P; Kontos, Christos K CK; Pappas, Efthimios E; Boutati, Eleni E; Scorilas, Andreas A; Fragoulis, Emmanuel G EG
Pharmacogenomics of Sulfonylureas Response in Relation to rs7754840 Polymorphisms in Cyclin-Dependent Kinase 5 Regulatory Subunit-associated Protein 1-like (CDKAL1) Gene in Iranian Type 2 Diabetes Patients.