Development and validation of a multivariable genotype-informed gestational diabetes prediction algorithm for clinical use in the Mexican population: insights into susceptibility mechanisms.
Bmj Open Diabetes Research & Care
Zulueta, Mirella M; Gallardo-Rincón, Héctor H; Martinez-Juarez, Luis Alberto LA; Lomelin-Gascon, Julieta J; Ortega-Montiel, Janinne J; Montoya, Alejandra A; Mendizabal, Leire L; Arregi, Maddi M; Martinez-Martinez, María de Los Angeles MLA; Camarillo Romero, Eneida Del Socorro EDS; Mendieta Zerón, Hugo H; Garduño García, José de Jesús JJ; Simón, Laureano L; Tapia-Conyer, Roberto R
Genetic variants for prediction of gestational diabetes mellitus and modulation of susceptibility by a nutritional intervention based on a Mediterranean diet.
Frontiers In Endocrinology
Ramos-Levi, Ana A; Barabash, Ana A; Valerio, Johanna J; García de la Torre, Nuria N; Mendizabal, Leire L; Zulueta, Mirella M; de Miguel, Maria Paz MP; Diaz, Angel A; Duran, Alejandra A; Familiar, Cristina C; Jimenez, Inés I; Del Valle, Laura L; Melero, Veronica V; Moraga, Inmaculada I; Herraiz, Miguel A MA; Torrejon, María José MJ; Arregi, Maddi M; Simón, Laureano L; Rubio, Miguel A MA; Calle-Pascual, Alfonso L AL
Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis.
Lancet (London, England)
Nazarzadeh, Milad M; Bidel, Zeinab Z; Canoy, Dexter D; Copland, Emma E; Wamil, Malgorzata M; Majert, Jeannette J; Smith Byrne, Karl K; Sundström, Johan J; Teo, Koon K; Davis, Barry R BR; Chalmers, John J; Pepine, Carl J CJ; Dehghan, Abbas A; Bennett, Derrick A DA; Smith, George Davey GD; Rahimi, Kazem K; ,
Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.
Nature Communications
Georges, Adrien A; Yang, Min-Lee ML; Berrandou, Takiy-Eddine TE; Bakker, Mark K MK; Dikilitas, Ozan O; Kiando, Soto Romuald SR; Ma, Lijiang L; Satterfield, Benjamin A BA; Sengupta, Sebanti S; Yu, Mengyao M; Deleuze, Jean-François JF; Dupré, Delia D; Hunker, Kristina L KL; Kyryachenko, Sergiy S; Liu, Lu L; Sayoud-Sadeg, Ines I; Amar, Laurence L; Brummett, Chad M CM; Coleman, Dawn M DM; d'Escamard, Valentina V; de Leeuw, Peter P; Fendrikova-Mahlay, Natalia N; Kadian-Dodov, Daniella D; Li, Jun Z JZ; Lorthioir, Aurélien A; Pappaccogli, Marco M; Prejbisz, Aleksander A; Smigielski, Witold W; Stanley, James C JC; Zawistowski, Matthew M; Zhou, Xiang X; Zöllner, Sebastian S; , ; , ; , ; Amouyel, Philippe P; De Buyzere, Marc L ML; Debette, Stéphanie S; Dobrowolski, Piotr P; Drygas, Wojciech W; Gornik, Heather L HL; Olin, Jeffrey W JW; Piwonski, Jerzy J; Rietzschel, Ernst R ER; Ruigrok, Ynte M YM; Vikkula, Miikka M; Warchol Celinska, Ewa E; Januszewicz, Andrzej A; Kullo, Iftikhar J IJ; Azizi, Michel M; Jeunemaitre, Xavier X; Persu, Alexandre A; Kovacic, Jason C JC; Ganesh, Santhi K SK; Bouatia-Naji, Nabila N
Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.
Nature Communications
Georges, Adrien A; Yang, Min-Lee ML; Berrandou, Takiy-Eddine TE; Bakker, Mark K MK; Dikilitas, Ozan O; Kiando, Soto Romuald SR; Ma, Lijiang L; Satterfield, Benjamin A BA; Sengupta, Sebanti S; Yu, Mengyao M; Deleuze, Jean-François JF; Dupré, Delia D; Hunker, Kristina L KL; Kyryachenko, Sergiy S; Liu, Lu L; Sayoud-Sadeg, Ines I; Amar, Laurence L; Brummett, Chad M CM; Coleman, Dawn M DM; d'Escamard, Valentina V; de Leeuw, Peter P; Fendrikova-Mahlay, Natalia N; Kadian-Dodov, Daniella D; Li, Jun Z JZ; Lorthioir, Aurélien A; Pappaccogli, Marco M; Prejbisz, Aleksander A; Smigielski, Witold W; Stanley, James C JC; Zawistowski, Matthew M; Zhou, Xiang X; Zöllner, Sebastian S; , ; , ; , ; Amouyel, Philippe P; De Buyzere, Marc L ML; Debette, Stéphanie S; Dobrowolski, Piotr P; Drygas, Wojciech W; Gornik, Heather L HL; Olin, Jeffrey W JW; Piwonski, Jerzy J; Rietzschel, Ernst R ER; Ruigrok, Ynte M YM; Vikkula, Miikka M; Warchol Celinska, Ewa E; Januszewicz, Andrzej A; Kullo, Iftikhar J IJ; Azizi, Michel M; , ; Jeunemaitre, Xavier X; Persu, Alexandre A; Kovacic, Jason C JC; Ganesh, Santhi K SK; Bouatia-Naji, Nabila N
All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes.
Wellcome Open Research
Hughes, Alice E AE; Hayes, M Geoffrey MG; Egan, Aoife M AM; Patel, Kashyap A KA; Scholtens, Denise M DM; Lowe, Lynn P LP; Lowe, William L WL; Dunne, Fidelma P FP; Hattersley, Andrew T AT; Freathy, Rachel M RM
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity.
The Journal Of Clinical Endocrinology And Metabolism
Deshmukh, Harshal A HA; Madsen, Anne Lundager AL; Viñuela, Ana A; Have, Christian Theil CT; Grarup, Niels N; Tura, Andrea A; Mahajan, Anubha A; Heggie, Alison J AJ; Koivula, Robert W RW; De Masi, Federico F; Tsirigos, Konstantinos K KK; Linneberg, Allan A; Drivsholm, Thomas T; Pedersen, Oluf O; Sørensen, Thorkild I A TIA; Astrup, Arne A; Gjesing, Anette A P AAP; Pavo, Imre I; Wood, Andrew R AR; Ruetten, Hartmut H; Jones, Angus G AG; Koopman, Anitra D M ADM; Cederberg, Henna H; Rutters, Femke F; Ridderstrale, Martin M; Laakso, Markku M; McCarthy, Mark I MI; Frayling, Tim M TM; Ferrannini, Ele E; Franks, Paul W PW; Pearson, Ewan R ER; Mari, Andrea A; Hansen, Torben T; Walker, Mark M
A genome-wide association and replication study of blood pressure in Ugandan early adolescents.
Molecular Genetics & Genomic Medicine
Lule, Swaib A SA; Mentzer, Alexander J AJ; Namara, Benigna B; Muwenzi, Allan G AG; Nassanga, Beatrice B; Kizito, Dennison D; Akurut, Helen H; Lubyayi, Lawrence L; Tumusiime, Josephine J; Zziwa, Christopher C; Akello, Florence F; Gurdasani, Deept D; Sandhu, Manjinder M; Smeeth, Liam L; Elliott, Alison M AM; Webb, Emily L EL
Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study.
Diabetes
Loomis, Stephanie J SJ; Li, Man M; Maruthur, Nisa M NM; Baldridge, Abigail S AS; North, Kari E KE; Mei, Hao H; Morrison, Alanna A; Carson, April P AP; Pankow, James S JS; Boerwinkle, Eric E; Scharpf, Robert R; Rasmussen-Torvik, Laura J LJ; Coresh, Josef J; Duggal, Priya P; Köttgen, Anna A; Selvin, Elizabeth E
Trans-ethnic meta-regression of genome-wide association studies accounting for ancestry increases power for discovery and improves fine-mapping resolution.
Human Molecular Genetics
Mägi, Reedik R; Horikoshi, Momoko M; Sofer, Tamar T; Mahajan, Anubha A; Kitajima, Hidetoshi H; Franceschini, Nora N; McCarthy, Mark I MI; , ; Morris, Andrew P AP
Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium.
Diabetologia
Bien, Stephanie A SA; Pankow, James S JS; Haessler, Jeffrey J; Lu, Yinchang Y; Pankratz, Nathan N; Rohde, Rebecca R RR; Tamuno, Alfred A; Carlson, Christopher S CS; Schumacher, Fredrick R FR; Bůžková, Petra P; Daviglus, Martha L ML; Lim, Unhee U; Fornage, Myriam M; Fernandez-Rhodes, Lindsay L; Avilés-Santa, Larissa L; Buyske, Steven S; Gross, Myron D MD; Graff, Mariaelisa M; Isasi, Carmen R CR; Kuller, Lewis H LH; Manson, JoAnn E JE; Matise, Tara C TC; Prentice, Ross L RL; Wilkens, Lynne R LR; Yoneyama, Sachiko S; Loos, Ruth J F RJF; Hindorff, Lucia A LA; Le Marchand, Loic L; North, Kari E KE; Haiman, Christopher A CA; Peters, Ulrike U; Kooperberg, Charles C
Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci.
Human Genetics
Fernández-Rhodes, Lindsay L; Gong, Jian J; Haessler, Jeffrey J; Franceschini, Nora N; Graff, Mariaelisa M; Nishimura, Katherine K KK; Wang, Yujie Y; Highland, Heather M HM; Yoneyama, Sachiko S; Bush, William S WS; Goodloe, Robert R; Ritchie, Marylyn D MD; Crawford, Dana D; Gross, Myron M; Fornage, Myriam M; Buzkova, Petra P; Tao, Ran R; Isasi, Carmen C; Avilés-Santa, Larissa L; Daviglus, Martha M; Mackey, Rachel H RH; Houston, Denise D; Gu, C Charles CC; Ehret, Georg G; Nguyen, Khanh-Dung H KH; Lewis, Cora E CE; Leppert, Mark M; Irvin, Marguerite R MR; Lim, Unhee U; Haiman, Christopher A CA; Le Marchand, Loic L; Schumacher, Fredrick F; Wilkens, Lynne L; Lu, Yingchang Y; Bottinger, Erwin P EP; Loos, Ruth J L RJL; Sheu, Wayne H-H WH; Guo, Xiuqing X; Lee, Wen-Jane WJ; Hai, Yang Y; Hung, Yi-Jen YJ; Absher, Devin D; Wu, I-Chien IC; Taylor, Kent D KD; Lee, I-Te IT; Liu, Yeheng Y; Wang, Tzung-Dau TD; Quertermous, Thomas T; Juang, Jyh-Ming J JJ; Rotter, Jerome I JI; Assimes, Themistocles T; Hsiung, Chao A CA; Chen, Yii-Der Ida YI; Prentice, Ross R; Kuller, Lewis H LH; Manson, JoAnn E JE; Kooperberg, Charles C; Smokowski, Paul P; Robinson, Whitney R WR; Gordon-Larsen, Penny P; Li, Rongling R; Hindorff, Lucia L; Buyske, Steven S; Matise, Tara C TC; Peters, Ulrike U; North, Kari E KE
Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium.
Diabetes
Palmer, Nicholette D ND; Wagenknecht, Lynne E LE; Langefeld, Carl D CD; Wang, Nan N; Buchanan, Thomas A TA; Xiang, Anny H AH; Allayee, Hooman H; Bergman, Richard N RN; Raffel, Leslie J LJ; Chen, Yii-Der Ida YD; Haritunians, Talin T; Fingerlin, Tasha T; Goodarzi, Mark O MO; Taylor, Kent D KD; Rotter, Jerome I JI; Watanabe, Richard M RM; Bowden, Donald W DW
Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study.
Plos One
Sohani, Zahra N ZN; Anand, Sonia S SS; Robiou-du-Pont, Sebastien S; Morrison, Katherine M KM; McDonald, Sarah D SD; Atkinson, Stephanie A SA; Teo, Koon K KK; Meyre, David D
Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
Human Molecular Genetics
Horikoshi, Momoko M; Pasquali, Lorenzo L; Wiltshire, Steven S; Huyghe, Jeroen R JR; Mahajan, Anubha A; Asimit, Jennifer L JL; Ferreira, Teresa T; Locke, Adam E AE; Robertson, Neil R NR; Wang, Xu X; Sim, Xueling X; Fujita, Hayato H; Hara, Kazuo K; Young, Robin R; Zhang, Weihua W; Choi, Sungkyoung S; Chen, Han H; Kaur, Ismeet I; Takeuchi, Fumihiko F; Fontanillas, Pierre P; Thuillier, Dorothée D; Yengo, Loic L; Below, Jennifer E JE; Tam, Claudia H T CH; Wu, Ying Y; Abecasis, Gonçalo G; Altshuler, David D; Bell, Graeme I GI; Blangero, John J; Burtt, Noél P NP; Duggirala, Ravindranath R; Florez, Jose C JC; Hanis, Craig L CL; Seielstad, Mark M; Atzmon, Gil G; Chan, Juliana C N JC; Ma, Ronald C W RC; Froguel, Philippe P; Wilson, James G JG; Bharadwaj, Dwaipayan D; Dupuis, Josee J; Meigs, James B JB; Cho, Yoon Shin YS; Park, Taesung T; Kooner, Jaspal S JS; Chambers, John C JC; Saleheen, Danish D; Kadowaki, Takashi T; Tai, E Shyong ES; Mohlke, Karen L KL; Cox, Nancy J NJ; Ferrer, Jorge J; Zeggini, Eleftheria E; Kato, Norihiro N; Teo, Yik Ying YY; Boehnke, Michael M; McCarthy, Mark I MI; Morris, Andrew P AP; ,
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Nature Genetics
Gaulton, Kyle J KJ; Ferreira, Teresa T; Lee, Yeji Y; Raimondo, Anne A; Mägi, Reedik R; Reschen, Michael E ME; Mahajan, Anubha A; Locke, Adam A; Rayner, N William NW; Robertson, Neil N; Scott, Robert A RA; Prokopenko, Inga I; Scott, Laura J LJ; Green, Todd T; Sparso, Thomas T; Thuillier, Dorothee D; Yengo, Loic L; Grallert, Harald H; Wahl, Simone S; Frånberg, Mattias M; Strawbridge, Rona J RJ; Kestler, Hans H; Chheda, Himanshu H; Eisele, Lewin L; Gustafsson, Stefan S; Steinthorsdottir, Valgerdur V; Thorleifsson, Gudmar G; Qi, Lu L; Karssen, Lennart C LC; van Leeuwen, Elisabeth M EM; Willems, Sara M SM; Li, Man M; Chen, Han H; Fuchsberger, Christian C; Kwan, Phoenix P; Ma, Clement C; Linderman, Michael M; Lu, Yingchang Y; Thomsen, Soren K SK; Rundle, Jana K JK; Beer, Nicola L NL; van de Bunt, Martijn M; Chalisey, Anil A; Kang, Hyun Min HM; Voight, Benjamin F BF; Abecasis, Gonçalo R GR; Almgren, Peter P; Baldassarre, Damiano D; Balkau, Beverley B; Benediktsson, Rafn R; Blüher, Matthias M; Boeing, Heiner H; Bonnycastle, Lori L LL; Bottinger, Erwin P EP; Burtt, Noël P NP; Carey, Jason J; Charpentier, Guillaume G; Chines, Peter S PS; Cornelis, Marilyn C MC; Couper, David J DJ; Crenshaw, Andrew T AT; van Dam, Rob M RM; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Eriksson, Johan G JG; Esko, Tonu T; Eury, Elodie E; Fadista, João J; Flannick, Jason J; Fontanillas, Pierre P; Fox, Caroline C; Franks, Paul W PW; Gertow, Karl K; Gieger, Christian C; Gigante, Bruna B; Gottesman, Omri O; Grant, George B GB; Grarup, Niels N; Groves, Christopher J CJ; Hassinen, Maija M; Have, Christian T CT; Herder, Christian C; Holmen, Oddgeir L OL; Hreidarsson, Astradur B AB; Humphries, Steve E SE; Hunter, David J DJ; Jackson, Anne U AU; Jonsson, Anna A; Jørgensen, Marit E ME; Jørgensen, Torben T; Kao, Wen-Hong L WH; Kerrison, Nicola D ND; Kinnunen, Leena L; Klopp, Norman N; Kong, Augustine A; Kovacs, Peter P; Kraft, Peter P; Kravic, Jasmina J; Langford, Cordelia C; Leander, Karin K; Liang, Liming L; Lichtner, Peter P; Lindgren, Cecilia M CM; Lindholm, Eero E; Linneberg, Allan A; Liu, Ching-Ti CT; Lobbens, Stéphane S; Luan, Jian'an J; Lyssenko, Valeriya V; Männistö, Satu S; McLeod, Olga O; Meyer, Julia J; Mihailov, Evelin E; Mirza, Ghazala G; Mühleisen, Thomas W TW; Müller-Nurasyid, Martina M; Navarro, Carmen C; Nöthen, Markus M MM; Oskolkov, Nikolay N NN; Owen, Katharine R KR; Palli, Domenico D; Pechlivanis, Sonali S; Peltonen, Leena L; Perry, John R B JR; Platou, Carl G P CG; Roden, Michael M; Ruderfer, Douglas D; Rybin, Denis D; van der Schouw, Yvonne T YT; Sennblad, Bengt B; Sigurðsson, Gunnar G; Stančáková, Alena A; Steinbach, Gerald G; Storm, Petter P; Strauch, Konstantin K; Stringham, Heather M HM; Sun, Qi Q; Thorand, Barbara B; Tikkanen, Emmi E; Tonjes, Anke A; Trakalo, Joseph J; Tremoli, Elena E; Tuomi, Tiinamaija T; Wennauer, Roman R; Wiltshire, Steven S; Wood, Andrew R AR; Zeggini, Eleftheria E; Dunham, Ian I; Birney, Ewan E; Pasquali, Lorenzo L; Ferrer, Jorge J; Loos, Ruth J F RJ; Dupuis, Josée J; Florez, Jose C JC; Boerwinkle, Eric E; Pankow, James S JS; van Duijn, Cornelia C; Sijbrands, Eric E; Meigs, James B JB; Hu, Frank B FB; Thorsteinsdottir, Unnur U; Stefansson, Kari K; Lakka, Timo A TA; Rauramaa, Rainer R; Stumvoll, Michael M; Pedersen, Nancy L NL; Lind, Lars L; Keinanen-Kiukaanniemi, Sirkka M SM; Korpi-Hyövälti, Eeva E; Saaristo, Timo E TE; Saltevo, Juha J; Kuusisto, Johanna J; Laakso, Markku M; Metspalu, Andres A; Erbel, Raimund R; Jöcke, Karl-Heinz KH; Moebus, Susanne S; Ripatti, Samuli S; Salomaa, Veikko V; Ingelsson, Erik E; Boehm, Bernhard O BO; Bergman, Richard N RN; Collins, Francis S FS; Mohlke, Karen L KL; Koistinen, Heikki H; Tuomilehto, Jaakko J; Hveem, Kristian K; Njølstad, Inger I; Deloukas, Panagiotis P; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; de Faire, Ulf U; Hamsten, Anders A; Illig, Thomas T; Peters, Annette A; Cauchi, Stephane S; Sladek, Rob R; Froguel, Philippe P; Hansen, Torben T; Pedersen, Oluf O; Morris, Andrew D AD; Palmer, Collin N A CN; Kathiresan, Sekar S; Melander, Olle O; Nilsson, Peter M PM; Groop, Leif C LC; Barroso, Inês I; Langenberg, Claudia C; Wareham, Nicholas J NJ; O'Callaghan, Christopher A CA; Gloyn, Anna L AL; Altshuler, David D; Boehnke, Michael M; Teslovich, Tanya M TM; McCarthy, Mark I MI; Morris, Andrew P AP; ,
A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease.
Nature Communications
Ahmad, Omar S OS; Morris, John A JA; Mujammami, Muhammad M; Forgetta, Vincenzo V; Leong, Aaron A; Li, Rui R; Turgeon, Maxime M; Greenwood, Celia M T CM; Thanassoulis, George G; Meigs, James B JB; Sladek, Robert R; Richards, J Brent JB
Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium.
Diabetes
Palmer, Nicholette D ND; Goodarzi, Mark O MO; Langefeld, Carl D CD; Wang, Nan N; Guo, Xiuqing X; Taylor, Kent D KD; Fingerlin, Tasha E TE; Norris, Jill M JM; Buchanan, Thomas A TA; Xiang, Anny H AH; Haritunians, Talin T; Ziegler, Julie T JT; Williams, Adrienne H AH; Stefanovski, Darko D; Cui, Jinrui J; Mackay, Adrienne W AW; Henkin, Leora F LF; Bergman, Richard N RN; Gao, Xiaoyi X; Gauderman, James J; Varma, Rohit R; Hanis, Craig L CL; Cox, Nancy J NJ; Highland, Heather M HM; Below, Jennifer E JE; Williams, Amy L AL; Burtt, Noel P NP; Aguilar-Salinas, Carlos A CA; Huerta-Chagoya, Alicia A; Gonzalez-Villalpando, Clicerio C; Orozco, Lorena L; Haiman, Christopher A CA; Tsai, Michael Y MY; Johnson, W Craig WC; Yao, Jie J; Rasmussen-Torvik, Laura L; Pankow, James J; Snively, Beverly B; Jackson, Rebecca D RD; Liu, Simin S; Nadler, Jerry L JL; Kandeel, Fouad F; Chen, Yii-Der I YD; Bowden, Donald W DW; Rich, Stephen S SS; Raffel, Leslie J LJ; Rotter, Jerome I JI; Watanabe, Richard M RM; Wagenknecht, Lynne E LE
T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.
Scientific Reports
Ghassibe-Sabbagh, Michella M; Haber, Marc M; Salloum, Angelique K AK; Al-Sarraj, Yasser Y; Akle, Yasmine Y; Hirbli, Kamal K; Romanos, Jihane J; Mouzaya, Francis F; Gauguier, Dominique D; Platt, Daniel E DE; El-Shanti, Hatem H; Zalloua, Pierre A PA
Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population.
Diabetologia
Kuo, Jane Z JZ; Sheu, Wayne Huey-Herng WH; Assimes, Themistocles L TL; Hung, Yi-Jen YJ; Absher, Devin D; Chiu, Yen-Feng YF; Mak, Jordan J; Wang, Jun-Sing JS; Kwon, Soonil S; Hsu, Chih-Cheng CC; Goodarzi, Mark O MO; Lee, I-Te IT; Knowles, Joshua W JW; Miller, Brittany E BE; Lee, Wen-Jane WJ; Juang, Jyh-Ming J JM; Wang, Tzung-Dau TD; Guo, Xiuqing X; Taylor, Kent D KD; Chuang, Lee-Ming LM; Hsiung, Chao A CA; Quertermous, Thomas T; Rotter, Jerome I JI; Chen, Yii-Der I YD
Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.
Diabetes
Hayes, M Geoffrey MG; Urbanek, Margrit M; Hivert, Marie-France MF; Armstrong, Loren L LL; Morrison, Jean J; Guo, Cong C; Lowe, Lynn P LP; Scheftner, Douglas A DA; Pluzhnikov, Anna A; Levine, David M DM; McHugh, Caitlin P CP; Ackerman, Christine M CM; Bouchard, Luigi L; Brisson, Diane D; Layden, Brian T BT; Mirel, Daniel D; Doheny, Kimberly F KF; Leya, Marysa V MV; Lown-Hecht, Rachel N RN; Dyer, Alan R AR; Metzger, Boyd E BE; Reddy, Timothy E TE; Cox, Nancy J NJ; Lowe, William L WL; ,
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
Nature Genetics
Scott, Robert A RA; Lagou, Vasiliki V; Welch, Ryan P RP; Wheeler, Eleanor E; Montasser, May E ME; Luan, Jian'an J; Mägi, Reedik R; Strawbridge, Rona J RJ; Rehnberg, Emil E; Gustafsson, Stefan S; Kanoni, Stavroula S; Rasmussen-Torvik, Laura J LJ; Yengo, Loïc L; Lecoeur, Cecile C; Shungin, Dmitry D; Sanna, Serena S; Sidore, Carlo C; Johnson, Paul C D PC; Jukema, J Wouter JW; Johnson, Toby T; Mahajan, Anubha A; Verweij, Niek N; Thorleifsson, Gudmar G; Hottenga, Jouke-Jan JJ; Shah, Sonia S; Smith, Albert V AV; Sennblad, Bengt B; Gieger, Christian C; Salo, Perttu P; Perola, Markus M; Timpson, Nicholas J NJ; Evans, David M DM; Pourcain, Beate St BS; Wu, Ying Y; Andrews, Jeanette S JS; Hui, Jennie J; Bielak, Lawrence F LF; Zhao, Wei W; Horikoshi, Momoko M; Navarro, Pau P; Isaacs, Aaron A; O'Connell, Jeffrey R JR; Stirrups, Kathleen K; Vitart, Veronique V; Hayward, Caroline C; Esko, Tõnu T; Mihailov, Evelin E; Fraser, Ross M RM; Fall, Tove T; Voight, Benjamin F BF; Raychaudhuri, Soumya S; Chen, Han H; Lindgren, Cecilia M CM; Morris, Andrew P AP; Rayner, Nigel W NW; Robertson, Neil N; Rybin, Denis D; Liu, Ching-Ti CT; Beckmann, Jacques S JS; Willems, Sara M SM; Chines, Peter S PS; Jackson, Anne U AU; Kang, Hyun Min HM; Stringham, Heather M HM; Song, Kijoung K; Tanaka, Toshiko T; Peden, John F JF; Goel, Anuj A; Hicks, Andrew A AA; An, Ping P; Müller-Nurasyid, Martina M; Franco-Cereceda, Anders A; Folkersen, Lasse L; Marullo, Letizia L; Jansen, Hanneke H; Oldehinkel, Albertine J AJ; Bruinenberg, Marcel M; Pankow, James S JS; North, Kari E KE; Forouhi, Nita G NG; Loos, Ruth J F RJ; Edkins, Sarah S; Varga, Tibor V TV; Hallmans, Göran G; Oksa, Heikki H; Antonella, Mulas M; Nagaraja, Ramaiah R; Trompet, Stella S; Ford, Ian I; Bakker, Stephan J L SJ; Kong, Augustine A; Kumari, Meena M; Gigante, Bruna B; Herder, Christian C; Munroe, Patricia B PB; Caulfield, Mark M; Antti, Jula J; Mangino, Massimo M; Small, Kerrin K; Miljkovic, Iva I; Liu, Yongmei Y; Atalay, Mustafa M; Kiess, Wieland W; James, Alan L AL; Rivadeneira, Fernando F; Uitterlinden, Andre G AG; Palmer, Colin N A CN; Doney, Alex S F AS; Willemsen, Gonneke G; Smit, Johannes H JH; Campbell, Susan S; Polasek, Ozren O; Bonnycastle, Lori L LL; Hercberg, Serge S; Dimitriou, Maria M; Bolton, Jennifer L JL; Fowkes, Gerard R GR; Kovacs, Peter P; Lindström, Jaana J; Zemunik, Tatijana T; Bandinelli, Stefania S; Wild, Sarah H SH; Basart, Hanneke V HV; Rathmann, Wolfgang W; Grallert, Harald H; , ; Maerz, Winfried W; Kleber, Marcus E ME; Boehm, Bernhard O BO; Peters, Annette A; Pramstaller, Peter P PP; Province, Michael A MA; Borecki, Ingrid B IB; Hastie, Nicholas D ND; Rudan, Igor I; Campbell, Harry H; Watkins, Hugh H; Farrall, Martin M; Stumvoll, Michael M; Ferrucci, Luigi L; Waterworth, Dawn M DM; Bergman, Richard N RN; Collins, Francis S FS; Tuomilehto, Jaakko J; Watanabe, Richard M RM; de Geus, Eco J C EJ; Penninx, Brenda W BW; Hofman, Albert A; Oostra, Ben A BA; Psaty, Bruce M BM; Vollenweider, Peter P; Wilson, James F JF; Wright, Alan F AF; Hovingh, G Kees GK; Metspalu, Andres A; Uusitupa, Matti M; Magnusson, Patrik K E PK; Kyvik, Kirsten O KO; Kaprio, Jaakko J; Price, Jackie F JF; Dedoussis, George V GV; Deloukas, Panos P; Meneton, Pierre P; Lind, Lars L; Boehnke, Michael M; Shuldiner, Alan R AR; van Duijn, Cornelia M CM; Morris, Andrew D AD; Toenjes, Anke A; Peyser, Patricia A PA; Beilby, John P JP; Körner, Antje A; Kuusisto, Johanna J; Laakso, Markku M; Bornstein, Stefan R SR; Schwarz, Peter E H PE; Lakka, Timo A TA; Rauramaa, Rainer R; Adair, Linda S LS; Smith, George Davey GD; Spector, Tim D TD; Illig, Thomas T; de Faire, Ulf U; Hamsten, Anders A; Gudnason, Vilmundur V; Kivimaki, Mika M; Hingorani, Aroon A; Keinanen-Kiukaanniemi, Sirkka M SM; Saaristo, Timo E TE; Boomsma, Dorret I DI; Stefansson, Kari K; van der Harst, Pim P; Dupuis, Josée J; Pedersen, Nancy L NL; Sattar, Naveed N; Harris, Tamara B TB; Cucca, Francesco F; Ripatti, Samuli S; Salomaa, Veikko V; Mohlke, Karen L KL; Balkau, Beverley B; Froguel, Philippe P; Pouta, Anneli A; Jarvelin, Marjo-Riitta MR; Wareham, Nicholas J NJ; Bouatia-Naji, Nabila N; McCarthy, Mark I MI; Franks, Paul W PW; Meigs, James B JB; Teslovich, Tanya M TM; Florez, Jose C JC; Langenberg, Claudia C; Ingelsson, Erik E; Prokopenko, Inga I; Barroso, Inês I
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Nature Genetics
Morris, Andrew P AP; Voight, Benjamin F BF; Teslovich, Tanya M TM; Ferreira, Teresa T; Segrè, Ayellet V AV; Steinthorsdottir, Valgerdur V; Strawbridge, Rona J RJ; Khan, Hassan H; Grallert, Harald H; Mahajan, Anubha A; Prokopenko, Inga I; Kang, Hyun Min HM; Dina, Christian C; Esko, Tonu T; Fraser, Ross M RM; Kanoni, Stavroula S; Kumar, Ashish A; Lagou, Vasiliki V; Langenberg, Claudia C; Luan, Jian'an J; Lindgren, Cecilia M CM; Müller-Nurasyid, Martina M; Pechlivanis, Sonali S; Rayner, N William NW; Scott, Laura J LJ; Wiltshire, Steven S; Yengo, Loic L; Kinnunen, Leena L; Rossin, Elizabeth J EJ; Raychaudhuri, Soumya S; Johnson, Andrew D AD; Dimas, Antigone S AS; Loos, Ruth J F RJ; Vedantam, Sailaja S; Chen, Han H; Florez, Jose C JC; Fox, Caroline C; Liu, Ching-Ti CT; Rybin, Denis D; Couper, David J DJ; Kao, Wen Hong L WH; Li, Man M; Cornelis, Marilyn C MC; Kraft, Peter P; Sun, Qi Q; van Dam, Rob M RM; Stringham, Heather M HM; Chines, Peter S PS; Fischer, Krista K; Fontanillas, Pierre P; Holmen, Oddgeir L OL; Hunt, Sarah E SE; Jackson, Anne U AU; Kong, Augustine A; Lawrence, Robert R; Meyer, Julia J; Perry, John R B JR; Platou, Carl G P CG; Potter, Simon S; Rehnberg, Emil E; Robertson, Neil N; Sivapalaratnam, Suthesh S; Stančáková, Alena A; Stirrups, Kathleen K; Thorleifsson, Gudmar G; Tikkanen, Emmi E; Wood, Andrew R AR; Almgren, Peter P; Atalay, Mustafa M; Benediktsson, Rafn R; Bonnycastle, Lori L LL; Burtt, Noël N; Carey, Jason J; Charpentier, Guillaume G; Crenshaw, Andrew T AT; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Emilsson, Valur V; Eury, Elodie E; Forsen, Tom T; Gertow, Karl K; Gigante, Bruna B; Grant, George B GB; Groves, Christopher J CJ; Guiducci, Candace C; Herder, Christian C; Hreidarsson, Astradur B AB; Hui, Jennie J; James, Alan A; Jonsson, Anna A; Rathmann, Wolfgang W; Klopp, Norman N; Kravic, Jasmina J; Krjutškov, Kaarel K; Langford, Cordelia C; Leander, Karin K; Lindholm, Eero E; Lobbens, Stéphane S; Männistö, Satu S; Mirza, Ghazala G; Mühleisen, Thomas W TW; Musk, Bill B; Parkin, Melissa M; Rallidis, Loukianos L; Saramies, Jouko J; Sennblad, Bengt B; Shah, Sonia S; Sigurðsson, Gunnar G; Silveira, Angela A; Steinbach, Gerald G; Thorand, Barbara B; Trakalo, Joseph J; Veglia, Fabrizio F; Wennauer, Roman R; Winckler, Wendy W; Zabaneh, Delilah D; Campbell, Harry H; van Duijn, Cornelia C; Uitterlinden, Andre G AG; Hofman, Albert A; Sijbrands, Eric E; Abecasis, Goncalo R GR; Owen, Katharine R KR; Zeggini, Eleftheria E; Trip, Mieke D MD; Forouhi, Nita G NG; Syvänen, Ann-Christine AC; Eriksson, Johan G JG; Peltonen, Leena L; Nöthen, Markus M MM; Balkau, Beverley B; Palmer, Colin N A CN; Lyssenko, Valeriya V; Tuomi, Tiinamaija T; Isomaa, Bo B; Hunter, David J DJ; Qi, Lu L; , ; , ; , ; , ; , ; Shuldiner, Alan R AR; Roden, Michael M; Barroso, Ines I; Wilsgaard, Tom T; Beilby, John J; Hovingh, Kees K; Price, Jackie F JF; Wilson, James F JF; Rauramaa, Rainer R; Lakka, Timo A TA; Lind, Lars L; Dedoussis, George G; Njølstad, Inger I; Pedersen, Nancy L NL; Khaw, Kay-Tee KT; Wareham, Nicholas J NJ; Keinanen-Kiukaanniemi, Sirkka M SM; Saaristo, Timo E TE; Korpi-Hyövälti, Eeva E; Saltevo, Juha J; Laakso, Markku M; Kuusisto, Johanna J; Metspalu, Andres A; Collins, Francis S FS; Mohlke, Karen L KL; Bergman, Richard N RN; Tuomilehto, Jaakko J; Boehm, Bernhard O BO; Gieger, Christian C; Hveem, Kristian K; Cauchi, Stephane S; Froguel, Philippe P; Baldassarre, Damiano D; Tremoli, Elena E; Humphries, Steve E SE; Saleheen, Danish D; Danesh, John J; Ingelsson, Erik E; Ripatti, Samuli S; Salomaa, Veikko V; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Moebus, Susanne S; Peters, Annette A; Illig, Thomas T; de Faire, Ulf U; Hamsten, Anders A; Morris, Andrew D AD; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; Boerwinkle, Eric E; Melander, Olle O; Kathiresan, Sekar S; Nilsson, Peter M PM; Deloukas, Panos P; Thorsteinsdottir, Unnur U; Groop, Leif C LC; Stefansson, Kari K; Hu, Frank F; Pankow, James S JS; Dupuis, Josée J; Meigs, James B JB; Altshuler, David D; Boehnke, Michael M; McCarthy, Mark I MI; ,
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
American Journal Of Human Genetics
Saxena, Richa R; Elbers, Clara C CC; Guo, Yiran Y; Peter, Inga I; Gaunt, Tom R TR; Mega, Jessica L JL; Lanktree, Matthew B MB; Tare, Archana A; Castillo, Berta Almoguera BA; Li, Yun R YR; Johnson, Toby T; Bruinenberg, Marcel M; Gilbert-Diamond, Diane D; Rajagopalan, Ramakrishnan R; Voight, Benjamin F BF; Balasubramanyam, Ashok A; Barnard, John J; Bauer, Florianne F; Baumert, Jens J; Bhangale, Tushar T; Böhm, Bernhard O BO; Braund, Peter S PS; Burton, Paul R PR; Chandrupatla, Hareesh R HR; Clarke, Robert R; Cooper-DeHoff, Rhonda M RM; Crook, Errol D ED; Davey-Smith, George G; Day, Ian N IN; de Boer, Anthonius A; de Groot, Mark C H MC; Drenos, Fotios F; Ferguson, Jane J; Fox, Caroline S CS; Furlong, Clement E CE; Gibson, Quince Q; Gieger, Christian C; Gilhuijs-Pederson, Lisa A LA; Glessner, Joseph T JT; Goel, Anuj A; Gong, Yan Y; Grant, Struan F A SF; Grobbee, Diederick E DE; Hastie, Claire C; Humphries, Steve E SE; Kim, Cecilia E CE; Kivimaki, Mika M; Kleber, Marcus M; Meisinger, Christa C; Kumari, Meena M; Langaee, Taimour Y TY; Lawlor, Debbie A DA; Li, Mingyao M; Lobmeyer, Maximilian T MT; Maitland-van der Zee, Anke-Hilse AH; Meijs, Matthijs F L MF; Molony, Cliona M CM; Morrow, David A DA; Murugesan, Gurunathan G; Musani, Solomon K SK; Nelson, Christopher P CP; Newhouse, Stephen J SJ; O'Connell, Jeffery R JR; Padmanabhan, Sandosh S; Palmen, Jutta J; Patel, Sanjey R SR; Pepine, Carl J CJ; Pettinger, Mary M; Price, Thomas S TS; Rafelt, Suzanne S; Ranchalis, Jane J; Rasheed, Asif A; Rosenthal, Elisabeth E; Ruczinski, Ingo I; Shah, Sonia S; Shen, Haiqing H; Silbernagel, Günther G; Smith, Erin N EN; Spijkerman, Annemieke W M AW; Stanton, Alice A; Steffes, Michael W MW; Thorand, Barbara B; Trip, Mieke M; van der Harst, Pim P; van der A, Daphne L DL; van Iperen, Erik P A EP; van Setten, Jessica J; van Vliet-Ostaptchouk, Jana V JV; Verweij, Niek N; Wolffenbuttel, Bruce H R BH; Young, Taylor T; Zafarmand, M Hadi MH; Zmuda, Joseph M JM; , ; , ; Boehnke, Michael M; Altshuler, David D; McCarthy, Mark M; Kao, W H Linda WH; Pankow, James S JS; Cappola, Thomas P TP; Sever, Peter P; Poulter, Neil N; Caulfield, Mark M; Dominiczak, Anna A; Shields, Denis C DC; Bhatt, Deepak L DL; Bhatt, Deepak D; Zhang, Li L; Curtis, Sean P SP; Danesh, John J; Casas, Juan P JP; van der Schouw, Yvonne T YT; Onland-Moret, N Charlotte NC; Doevendans, Pieter A PA; Dorn, Gerald W GW; Farrall, Martin M; FitzGerald, Garret A GA; Hamsten, Anders A; Hegele, Robert R; Hingorani, Aroon D AD; Hofker, Marten H MH; Huggins, Gordon S GS; Illig, Thomas T; Jarvik, Gail P GP; Johnson, Julie A JA; Klungel, Olaf H OH; Knowler, William C WC; Koenig, Wolfgang W; März, Winfried W; Meigs, James B JB; Melander, Olle O; Munroe, Patricia B PB; Mitchell, Braxton D BD; Bielinski, Susan J SJ; Rader, Daniel J DJ; Reilly, Muredach P MP; Rich, Stephen S SS; Rotter, Jerome I JI; Saleheen, Danish D; Samani, Nilesh J NJ; Schadt, Eric E EE; Shuldiner, Alan R AR; Silverstein, Roy R; Kottke-Marchant, Kandice K; Talmud, Philippa J PJ; Watkins, Hugh H; Asselbergs, Folkert W FW; Asselbergs, Folkert F; de Bakker, Paul I W PI; McCaffery, Jeanne J; Wijmenga, Cisca C; Sabatine, Marc S MS; Wilson, James G JG; Reiner, Alex A; Bowden, Donald W DW; Hakonarson, Hakon H; Siscovick, David S DS; Keating, Brendan J BJ
Association of type 2 diabetes susceptibility loci with one-year weight loss in the look AHEAD clinical trial.
Obesity (Silver Spring, Md.)
Peter, Inga I; McCaffery, Jeanne M JM; Kelley-Hedgepeth, Alyson A; Hakonarson, Hakon H; Reis, Steven S; Wagenknecht, Lynne E LE; Kopin, Alan S AS; Huggins, Gondon S GS; ,