Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population.
Genes
Binjawhar, Dalal N DN; Ansari, Mohammed G A MGA; Sabico, Shaun S; Hussain, Syed Danish SD; Alenad, Amal M AM; Alokail, Majed S MS; Al-Masri, Abeer A AA; Al-Daghri, Nasser M NM
Substitution of Carbohydrates for Fats and Risk of Type 2 Diabetes among Korean Middle-Aged Adults: Findings from the Korean Genome and Epidemiology Study.
Association between functional genetic variants in retinoid X receptor-α/γ and the risk of gestational diabetes mellitus in a southern Chinese population.
Relationship between glucose homeostasis and obesity in early life-a study of Italian children and adolescents.
Human Molecular Genetics
Balkhiyarova, Zhanna Z; Luciano, Rosa R; Kaakinen, Marika M; Ulrich, Anna A; Shmeliov, Aleksey A; Bianchi, Marzia M; Chioma, Laura L; Dallapiccola, Bruno B; Prokopenko, Inga I; Manco, Melania M
Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.
Scientific Reports
Christodoulou, Maria-Ioanna MI; Avgeris, Margaritis M; Kokkinopoulou, Ioanna I; Maratou, Eirini E; Mitrou, Panayota P; Kontos, Christos K CK; Pappas, Efthimios E; Boutati, Eleni E; Scorilas, Andreas A; Fragoulis, Emmanuel G EG
Dietary and genetic risk scores and incidence of type 2 diabetes.
Genes & Nutrition
Ericson, Ulrika U; Hindy, George G; Drake, Isabel I; Schulz, Christina-Alexandra CA; Brunkwall, Louise L; Hellstrand, Sophie S; Almgren, Peter P; Orho-Melander, Marju M
Influence of genetic ancestry and socioeconomic status on type 2 diabetes in the diverse Colombian populations of Chocó and Antioquia.
Scientific Reports
Chande, Aroon T AT; Rowell, Jessica J; Rishishwar, Lavanya L; Conley, Andrew B AB; Norris, Emily T ET; Valderrama-Aguirre, Augusto A; Medina-Rivas, Miguel A MA; Jordan, I King IK
Several type 2 diabetes-associated variants in genes annotated to WNT signaling interact with dietary fiber in relation to incidence of type 2 diabetes.
Genes & Nutrition
Hindy, George G; Mollet, Inês G IG; Rukh, Gull G; Ericson, Ulrika U; Orho-Melander, Marju M
Association of Type 2 Diabetes Mellitus related SNP genotypes with altered serum adipokine levels and metabolic syndrome phenotypes.
International Journal Of Clinical And Experimental Medicine
Al-Daghri, Nasser M NM; Al-Attas, Omar S OS; Krishnaswamy, Soundararajan S; Mohammed, Abdul Khader AK; Alenad, Amal M AM; Chrousos, George P GP; Alokail, Majed S MS
T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.
Scientific Reports
Ghassibe-Sabbagh, Michella M; Haber, Marc M; Salloum, Angelique K AK; Al-Sarraj, Yasser Y; Akle, Yasmine Y; Hirbli, Kamal K; Romanos, Jihane J; Mouzaya, Francis F; Gauguier, Dominique D; Platt, Daniel E DE; El-Shanti, Hatem H; Zalloua, Pierre A PA
A comparison of type 2 diabetes risk allele load between African Americans and European Americans.
Human Genetics
Keaton, Jacob M JM; Cooke Bailey, Jessica N JN; Palmer, Nicholette D ND; Freedman, Barry I BI; Langefeld, Carl D CD; Ng, Maggie C Y MC; Bowden, Donald W DW
Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Plos Genetics
Ng, Maggie C Y MC; Shriner, Daniel D; Chen, Brian H BH; Li, Jiang J; Chen, Wei-Min WM; Guo, Xiuqing X; Liu, Jiankang J; Bielinski, Suzette J SJ; Yanek, Lisa R LR; Nalls, Michael A MA; Comeau, Mary E ME; Rasmussen-Torvik, Laura J LJ; Jensen, Richard A RA; Evans, Daniel S DS; Sun, Yan V YV; An, Ping P; Patel, Sanjay R SR; Lu, Yingchang Y; Long, Jirong J; Armstrong, Loren L LL; Wagenknecht, Lynne L; Yang, Lingyao L; Snively, Beverly M BM; Palmer, Nicholette D ND; Mudgal, Poorva P; Langefeld, Carl D CD; Keene, Keith L KL; Freedman, Barry I BI; Mychaleckyj, Josyf C JC; Nayak, Uma U; Raffel, Leslie J LJ; Goodarzi, Mark O MO; Chen, Y-D Ida YD; Taylor, Herman A HA; Correa, Adolfo A; Sims, Mario M; Couper, David D; Pankow, James S JS; Boerwinkle, Eric E; Adeyemo, Adebowale A; Doumatey, Ayo A; Chen, Guanjie G; Mathias, Rasika A RA; Vaidya, Dhananjay D; Singleton, Andrew B AB; Zonderman, Alan B AB; Igo, Robert P RP; Sedor, John R JR; , ; Kabagambe, Edmond K EK; Siscovick, David S DS; McKnight, Barbara B; Rice, Kenneth K; Liu, Yongmei Y; Hsueh, Wen-Chi WC; Zhao, Wei W; Bielak, Lawrence F LF; Kraja, Aldi A; Province, Michael A MA; Bottinger, Erwin P EP; Gottesman, Omri O; Cai, Qiuyin Q; Zheng, Wei W; Blot, William J WJ; Lowe, William L WL; Pacheco, Jennifer A JA; Crawford, Dana C DC; , ; , ; Grundberg, Elin E; , ; Rich, Stephen S SS; Hayes, M Geoffrey MG; Shu, Xiao-Ou XO; Loos, Ruth J F RJ; Borecki, Ingrid B IB; Peyser, Patricia A PA; Cummings, Steven R SR; Psaty, Bruce M BM; Fornage, Myriam M; Iyengar, Sudha K SK; Evans, Michele K MK; Becker, Diane M DM; Kao, W H Linda WH; Wilson, James G JG; Rotter, Jerome I JI; Sale, Michèle M MM; Liu, Simin S; Rotimi, Charles N CN; Bowden, Donald W DW; ,
Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.
Diabetes
Dimas, Antigone S AS; Lagou, Vasiliki V; Barker, Adam A; Knowles, Joshua W JW; Mägi, Reedik R; Hivert, Marie-France MF; Benazzo, Andrea A; Rybin, Denis D; Jackson, Anne U AU; Stringham, Heather M HM; Song, Ci C; Fischer-Rosinsky, Antje A; Boesgaard, Trine Welløv TW; Grarup, Niels N; Abbasi, Fahim A FA; Assimes, Themistocles L TL; Hao, Ke K; Yang, Xia X; Lecoeur, Cécile C; Barroso, Inês I; Bonnycastle, Lori L LL; Böttcher, Yvonne Y; Bumpstead, Suzannah S; Chines, Peter S PS; Erdos, Michael R MR; Graessler, Jurgen J; Kovacs, Peter P; Morken, Mario A MA; Narisu, Narisu N; Payne, Felicity F; Stancakova, Alena A; Swift, Amy J AJ; Tönjes, Anke A; Bornstein, Stefan R SR; Cauchi, Stéphane S; Froguel, Philippe P; Meyre, David D; Schwarz, Peter E H PE; Häring, Hans-Ulrich HU; Smith, Ulf U; Boehnke, Michael M; Bergman, Richard N RN; Collins, Francis S FS; Mohlke, Karen L KL; Tuomilehto, Jaakko J; Quertemous, Thomas T; Lind, Lars L; Hansen, Torben T; Pedersen, Oluf O; Walker, Mark M; Pfeiffer, Andreas F H AF; Spranger, Joachim J; Stumvoll, Michael M; Meigs, James B JB; Wareham, Nicholas J NJ; Kuusisto, Johanna J; Laakso, Markku M; Langenberg, Claudia C; Dupuis, Josée J; Watanabe, Richard M RM; Florez, Jose C JC; Ingelsson, Erik E; McCarthy, Mark I MI; Prokopenko, Inga I; ,
Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population.
Diabetologia
Kuo, Jane Z JZ; Sheu, Wayne Huey-Herng WH; Assimes, Themistocles L TL; Hung, Yi-Jen YJ; Absher, Devin D; Chiu, Yen-Feng YF; Mak, Jordan J; Wang, Jun-Sing JS; Kwon, Soonil S; Hsu, Chih-Cheng CC; Goodarzi, Mark O MO; Lee, I-Te IT; Knowles, Joshua W JW; Miller, Brittany E BE; Lee, Wen-Jane WJ; Juang, Jyh-Ming J JM; Wang, Tzung-Dau TD; Guo, Xiuqing X; Taylor, Kent D KD; Chuang, Lee-Ming LM; Hsiung, Chao A CA; Quertermous, Thomas T; Rotter, Jerome I JI; Chen, Yii-Der I YD
RNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation.
Plos One
Haney, Steven S; Zhao, Juan J; Tiwari, Shiwani S; Eng, Kurt K; Guey, Lin T LT; Tien, Eric E
Quick, "imputation-free" meta-analysis with proxy-SNPs.
Bmc Bioinformatics
Meesters, Christian C; Leber, Markus M; Herold, Christine C; Angisch, Marina M; Mattheisen, Manuel M; Drichel, Dmitriy D; Lacour, André A; Becker, Tim T
A genome-wide association study of gestational diabetes mellitus in Korean women.
Diabetes
Kwak, Soo Heon SH; Kim, Sung-Hoon SH; Cho, Young Min YM; Go, Min Jin MJ; Cho, Yoon Shin YS; Choi, Sung Hee SH; Moon, Min Kyong MK; Jung, Hye Seung HS; Shin, Hyoung Doo HD; Kang, Hyun Min HM; Cho, Nam H NH; Lee, In Kyu IK; Kim, Seong Yeon SY; Han, Bok-Ghee BG; Jang, Hak C HC; Park, Kyong Soo KS