Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis.
Lancet (London, England)
Nazarzadeh, Milad M; Bidel, Zeinab Z; Canoy, Dexter D; Copland, Emma E; Wamil, Malgorzata M; Majert, Jeannette J; Smith Byrne, Karl K; Sundström, Johan J; Teo, Koon K; Davis, Barry R BR; Chalmers, John J; Pepine, Carl J CJ; Dehghan, Abbas A; Bennett, Derrick A DA; Smith, George Davey GD; Rahimi, Kazem K; ,
A genome-wide association and replication study of blood pressure in Ugandan early adolescents.
Molecular Genetics & Genomic Medicine
Lule, Swaib A SA; Mentzer, Alexander J AJ; Namara, Benigna B; Muwenzi, Allan G AG; Nassanga, Beatrice B; Kizito, Dennison D; Akurut, Helen H; Lubyayi, Lawrence L; Tumusiime, Josephine J; Zziwa, Christopher C; Akello, Florence F; Gurdasani, Deept D; Sandhu, Manjinder M; Smeeth, Liam L; Elliott, Alison M AM; Webb, Emily L EL
Genome-wide association study of medication-use and associated disease in the UK Biobank.
Nature Communications
Wu, Yeda Y; Byrne, Enda M EM; Zheng, Zhili Z; Kemper, Kathryn E KE; Yengo, Loic L; Mallett, Andrew J AJ; Yang, Jian J; Visscher, Peter M PM; Wray, Naomi R NR
A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features.
Scientific Reports
Fetit, Ahmed E AE; Doney, Alexander S AS; Hogg, Stephen S; Wang, Ruixuan R; MacGillivray, Tom T; Wardlaw, Joanna M JM; Doubal, Fergus N FN; McKay, Gareth J GJ; McKenna, Stephen S; Trucco, Emanuele E
Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits.
Plos One
Sofer, Tamar T; Baier, Leslie J LJ; Browning, Sharon R SR; Thornton, Timothy A TA; Talavera, Gregory A GA; Wassertheil-Smoller, Sylvia S; Daviglus, Martha L ML; Hanson, Robert R; Kobes, Sayuko S; Cooper, Richard S RS; Cai, Jianwen J; Levy, Daniel D; Reiner, Alex P AP; Franceschini, Nora N
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos.
Scientific Reports
Sofer, Tamar T; Wong, Quenna Q; Hartwig, Fernando P FP; Taylor, Kent K; Warren, Helen R HR; Evangelou, Evangelos E; Cabrera, Claudia P CP; Levy, Daniel D; Kramer, Holly H; Lange, Leslie A LA; Horta, Bernardo L BL; , ; Kerr, Kathleen F KF; Reiner, Alex P AP; Franceschini, Nora N
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
Hypertension (Dallas, Tex. : 1979)
Wain, Louise V LV; Vaez, Ahmad A; Jansen, Rick R; Joehanes, Roby R; van der Most, Peter J PJ; Erzurumluoglu, A Mesut AM; O'Reilly, Paul F PF; Cabrera, Claudia P CP; Warren, Helen R HR; Rose, Lynda M LM; Verwoert, Germaine C GC; Hottenga, Jouke-Jan JJ; Strawbridge, Rona J RJ; Esko, Tonu T; Arking, Dan E DE; Hwang, Shih-Jen SJ; Guo, Xiuqing X; Kutalik, Zoltan Z; Trompet, Stella S; Shrine, Nick N; Teumer, Alexander A; Ried, Janina S JS; Bis, Joshua C JC; Smith, Albert V AV; Amin, Najaf N; Nolte, Ilja M IM; Lyytikäinen, Leo-Pekka LP; Mahajan, Anubha A; Wareham, Nicholas J NJ; Hofer, Edith E; Joshi, Peter K PK; Kristiansson, Kati K; Traglia, Michela M; Havulinna, Aki S AS; Goel, Anuj A; Nalls, Mike A MA; Sõber, Siim S; Vuckovic, Dragana D; Luan, Jian'an J; Del Greco M, Fabiola F; Ayers, Kristin L KL; Marrugat, Jaume J; Ruggiero, Daniela D; Lopez, Lorna M LM; Niiranen, Teemu T; Enroth, Stefan S; Jackson, Anne U AU; Nelson, Christopher P CP; Huffman, Jennifer E JE; Zhang, Weihua W; Marten, Jonathan J; Gandin, Ilaria I; Harris, Sarah E SE; Zemunik, Tatijana T; Lu, Yingchang Y; Evangelou, Evangelos E; Shah, Nabi N; de Borst, Martin H MH; Mangino, Massimo M; Prins, Bram P BP; Campbell, Archie A; Li-Gao, Ruifang R; Chauhan, Ganesh G; Oldmeadow, Christopher C; Abecasis, Gonçalo G; Abedi, Maryam M; Barbieri, Caterina M CM; Barnes, Michael R MR; Batini, Chiara C; Beilby, John J; Blake, Tineka T; Boehnke, Michael M; Bottinger, Erwin P EP; Braund, Peter S PS; Brown, Morris M; Brumat, Marco M; Campbell, Harry H; Chambers, John C JC; Cocca, Massimiliano M; Collins, Francis F; Connell, John J; Cordell, Heather J HJ; Damman, Jeffrey J JJ; Davies, Gail G; de Geus, Eco J EJ; de Mutsert, Renée R; Deelen, Joris J; Demirkale, Yusuf Y; Doney, Alex S F ASF; Dörr, Marcus M; Farrall, Martin M; Ferreira, Teresa T; Frånberg, Mattias M; Gao, He H; Giedraitis, Vilmantas V; Gieger, Christian C; Giulianini, Franco F; Gow, Alan J AJ; Hamsten, Anders A; Harris, Tamara B TB; Hofman, Albert A; Holliday, Elizabeth G EG; Hui, Jennie J; Jarvelin, Marjo-Riitta MR; Johansson, Åsa Å; Johnson, Andrew D AD; Jousilahti, Pekka P; Jula, Antti A; Kähönen, Mika M; Kathiresan, Sekar S; Khaw, Kay-Tee KT; Kolcic, Ivana I; Koskinen, Seppo S; Langenberg, Claudia C; Larson, Marty M; Launer, Lenore J LJ; Lehne, Benjamin B; Liewald, David C M DCM; Lin, Li L; Lind, Lars L; Mach, François F; Mamasoula, Chrysovalanto C; Menni, Cristina C; Mifsud, Borbala B; Milaneschi, Yuri Y; Morgan, Anna A; Morris, Andrew D AD; Morrison, Alanna C AC; Munson, Peter J PJ; Nandakumar, Priyanka P; Nguyen, Quang Tri QT; Nutile, Teresa T; Oldehinkel, Albertine J AJ; Oostra, Ben A BA; Org, Elin E; Padmanabhan, Sandosh S; Palotie, Aarno A; Paré, Guillaume G; Pattie, Alison A; Penninx, Brenda W J H BWJH; Poulter, Neil N; Pramstaller, Peter P PP; Raitakari, Olli T OT; Ren, Meixia M; Rice, Kenneth K; Ridker, Paul M PM; Riese, Harriëtte H; Ripatti, Samuli S; Robino, Antonietta A; Rotter, Jerome I JI; Rudan, Igor I; Saba, Yasaman Y; Saint Pierre, Aude A; Sala, Cinzia F CF; Sarin, Antti-Pekka AP; Schmidt, Reinhold R; Scott, Rodney R; Seelen, Marc A MA; Shields, Denis C DC; Siscovick, David D; Sorice, Rossella R; Stanton, Alice A; Stott, David J DJ; Sundström, Johan J; Swertz, Morris M; Taylor, Kent D KD; Thom, Simon S; Tzoulaki, Ioanna I; Tzourio, Christophe C; Uitterlinden, André G AG; Völker, Uwe U; Vollenweider, Peter P; Wild, Sarah S; Willemsen, Gonneke G; Wright, Alan F AF; Yao, Jie J; Thériault, Sébastien S; Conen, David D; Attia, John J; Sever, Peter P; Debette, Stéphanie S; Mook-Kanamori, Dennis O DO; Zeggini, Eleftheria E; Spector, Tim D TD; van der Harst, Pim P; Palmer, Colin N A CNA; Vergnaud, Anne-Claire AC; Loos, Ruth J F RJF; Polasek, Ozren O; Starr, John M JM; Girotto, Giorgia G; Hayward, Caroline C; Kooner, Jaspal S JS; Lindgren, Cecila M CM; Vitart, Veronique V; Samani, Nilesh J NJ; Tuomilehto, Jaakko J; Gyllensten, Ulf U; Knekt, Paul P; Deary, Ian J IJ; Ciullo, Marina M; Elosua, Roberto R; Keavney, Bernard D BD; Hicks, Andrew A AA; Scott, Robert A RA; Gasparini, Paolo P; Laan, Maris M; Liu, YongMei Y; Watkins, Hugh H; Hartman, Catharina A CA; Salomaa, Veikko V; Toniolo, Daniela D; Perola, Markus M; Wilson, James F JF; Schmidt, Helena H; Zhao, Jing Hua JH; Lehtimäki, Terho T; van Duijn, Cornelia M CM; Gudnason, Vilmundur V; Psaty, Bruce M BM; Peters, Annette A; Rettig, Rainer R; James, Alan A; Jukema, J Wouter JW; Strachan, David P DP; Palmas, Walter W; Metspalu, Andres A; Ingelsson, Erik E; Boomsma, Dorret I DI; Franco, Oscar H OH; Bochud, Murielle M; Newton-Cheh, Christopher C; Munroe, Patricia B PB; Elliott, Paul P; Chasman, Daniel I DI; Chakravarti, Aravinda A; Knight, Joanne J; Morris, Andrew P AP; Levy, Daniel D; Tobin, Martin D MD; Snieder, Harold H; Caulfield, Mark J MJ; Ehret, Georg B GB
Systolic Blood Pressure and Risk of Type 2 Diabetes: A Mendelian Randomization Study.
Diabetes
Aikens, Rachael C RC; Zhao, Wei W; Saleheen, Danish D; Reilly, Muredach P MP; Epstein, Stephen E SE; Tikkanen, Emmi E; Salomaa, Veikko V; Voight, Benjamin F BF
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Nature Genetics
Kato, Norihiro N; Loh, Marie M; Takeuchi, Fumihiko F; Verweij, Niek N; Wang, Xu X; Zhang, Weihua W; Kelly, Tanika N TN; Saleheen, Danish D; Lehne, Benjamin B; Leach, Irene Mateo IM; Drong, Alexander W AW; Abbott, James J; Wahl, Simone S; Tan, Sian-Tsung ST; Scott, William R WR; Campanella, Gianluca G; Chadeau-Hyam, Marc M; Afzal, Uzma U; Ahluwalia, Tarunveer S TS; Bonder, Marc Jan MJ; Chen, Peng P; Dehghan, Abbas A; Edwards, Todd L TL; Esko, Tõnu T; Go, Min Jin MJ; Harris, Sarah E SE; Hartiala, Jaana J; Kasela, Silva S; Kasturiratne, Anuradhani A; Khor, Chiea-Chuen CC; Kleber, Marcus E ME; Li, Huaixing H; Yu Mok, Zuan Z; Nakatochi, Masahiro M; Sapari, Nur Sabrina NS; Saxena, Richa R; Stewart, Alexandre F R AFR; Stolk, Lisette L; Tabara, Yasuharu Y; Teh, Ai Ling AL; Wu, Ying Y; Wu, Jer-Yuarn JY; Zhang, Yi Y; Aits, Imke I; Da Silva Couto Alves, Alexessander A; Das, Shikta S; Dorajoo, Rajkumar R; Hopewell, Jemma C JC; Kim, Yun Kyoung YK; Koivula, Robert W RW; Luan, Jian'an J; Lyytikäinen, Leo-Pekka LP; Nguyen, Quang N QN; Pereira, Mark A MA; Postmus, Iris I; Raitakari, Olli T OT; Scannell Bryan, Molly M; Scott, Robert A RA; Sorice, Rossella R; Tragante, Vinicius V; Traglia, Michela M; White, Jon J; Yamamoto, Ken K; Zhang, Yonghong Y; Adair, Linda S LS; Ahmed, Alauddin A; Akiyama, Koichi K; Asif, Rasheed R; Aung, Tin T; Barroso, Inês I; Bjonnes, Andrew A; Braun, Timothy R TR; Cai, Hui H; Chang, Li-Ching LC; Chen, Chien-Hsiun CH; Cheng, Ching-Yu CY; Chong, Yap-Seng YS; Collins, Rory R; Courtney, Regina R; Davies, Gail G; Delgado, Graciela G; Do, Loi D LD; Doevendans, Pieter A PA; Gansevoort, Ron T RT; Gao, Yu-Tang YT; Grammer, Tanja B TB; Grarup, Niels N; Grewal, Jagvir J; Gu, Dongfeng D; Wander, Gurpreet S GS; Hartikainen, Anna-Liisa AL; Hazen, Stanley L SL; He, Jing J; Heng, Chew-Kiat CK; Hixson, James E JE; Hofman, Albert A; Hsu, Chris C; Huang, Wei W; Husemoen, Lise L N LLN; Hwang, Joo-Yeon JY; Ichihara, Sahoko S; Igase, Michiya M; Isono, Masato M; Justesen, Johanne M JM; Katsuya, Tomohiro T; Kibriya, Muhammad G MG; Kim, Young Jin YJ; Kishimoto, Miyako M; Koh, Woon-Puay WP; Kohara, Katsuhiko K; Kumari, Meena M; Kwek, Kenneth K; Lee, Nanette R NR; Lee, Jeannette J; Liao, Jiemin J; Lieb, Wolfgang W; Liewald, David C M DCM; Matsubara, Tatsuaki T; Matsushita, Yumi Y; Meitinger, Thomas T; Mihailov, Evelin E; Milani, Lili L; Mills, Rebecca R; Mononen, Nina N; Müller-Nurasyid, Martina M; Nabika, Toru T; Nakashima, Eitaro E; Ng, Hong Kiat HK; Nikus, Kjell K; Nutile, Teresa T; Ohkubo, Takayoshi T; Ohnaka, Keizo K; Parish, Sarah S; Paternoster, Lavinia L; Peng, Hao H; Peters, Annette A; Pham, Son T ST; Pinidiyapathirage, Mohitha J MJ; Rahman, Mahfuzar M; Rakugi, Hiromi H; Rolandsson, Olov O; Ann Rozario, Michelle M; Ruggiero, Daniela D; Sala, Cinzia F CF; Sarju, Ralhan R; Shimokawa, Kazuro K; Snieder, Harold H; Sparsø, Thomas T; Spiering, Wilko W; Starr, John M JM; Stott, David J DJ; Stram, Daniel O DO; Sugiyama, Takao T; Szymczak, Silke S; Tang, W H Wilson WHW; Tong, Lin L; Trompet, Stella S; Turjanmaa, Väinö V; Ueshima, Hirotsugu H; Uitterlinden, André G AG; Umemura, Satoshi S; Vaarasmaki, Marja M; van Dam, Rob M RM; van Gilst, Wiek H WH; van Veldhuisen, Dirk J DJ; Viikari, Jorma S JS; Waldenberger, Melanie M; Wang, Yiqin Y; Wang, Aili A; Wilson, Rory R; Wong, Tien-Yin TY; Xiang, Yong-Bing YB; Yamaguchi, Shuhei S; Ye, Xingwang X; Young, Robin D RD; Young, Terri L TL; Yuan, Jian-Min JM; Zhou, Xueya X; Asselbergs, Folkert W FW; Ciullo, Marina M; Clarke, Robert R; Deloukas, Panos P; Franke, Andre A; Franks, Paul W PW; Franks, Steve S; Friedlander, Yechiel Y; Gross, Myron D MD; Guo, Zhirong Z; Hansen, Torben T; Jarvelin, Marjo-Riitta MR; Jørgensen, Torben T; Jukema, J Wouter JW; Kähönen, Mika M; Kajio, Hiroshi H; Kivimaki, Mika M; Lee, Jong-Young JY; Lehtimäki, Terho T; Linneberg, Allan A; Miki, Tetsuro T; Pedersen, Oluf O; Samani, Nilesh J NJ; Sørensen, Thorkild I A TIA; Takayanagi, Ryoichi R; Toniolo, Daniela D; , ; , ; , ; , ; Ahsan, Habibul H; Allayee, Hooman H; Chen, Yuan-Tsong YT; Danesh, John J; Deary, Ian J IJ; Franco, Oscar H OH; Franke, Lude L; Heijman, Bastiaan T BT; Holbrook, Joanna D JD; Isaacs, Aaron A; Kim, Bong-Jo BJ; Lin, Xu X; Liu, Jianjun J; März, Winfried W; Metspalu, Andres A; Mohlke, Karen L KL; Sanghera, Dharambir K DK; Shu, Xiao-Ou XO; van Meurs, Joyce B J JBJ; Vithana, Eranga E; Wickremasinghe, Ananda R AR; Wijmenga, Cisca C; Wolffenbuttel, Bruce H W BHW; Yokota, Mitsuhiro M; Zheng, Wei W; Zhu, Dingliang D; Vineis, Paolo P; Kyrtopoulos, Soterios A SA; Kleinjans, Jos C S JCS; McCarthy, Mark I MI; Soong, Richie R; Gieger, Christian C; Scott, James J; Teo, Yik-Ying YY; He, Jiang J; Elliott, Paul P; Tai, E Shyong ES; van der Harst, Pim P; Kooner, Jaspal S JS; Chambers, John C JC
Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group.
Diabetes/Metabolism Research And Reviews
Malhotra, Alka A; Igo, Robert P RP; Thameem, Farook F; Kao, W H Linda WH; Abboud, Hanna E HE; Adler, Sharon G SG; Arar, Nedal H NH; Bowden, Donald W DW; Duggirala, Ravindranath R; Freedman, Barry I BI; Goddard, Katrina A B KA; Ipp, Eli E; Iyengar, Sudha K SK; Kimmel, Paul L PL; Knowler, William C WC; Kohn, Orly O; Leehey, David D; Meoni, Lucy A LA; Nelson, Robert G RG; Nicholas, Susanne B SB; Parekh, Rulan S RS; Rich, Stephen S SS; Chen, Yii-Der I YD; Saad, Mohammed F MF; Scavini, Marina M; Schelling, Jeffrey R JR; Sedor, John R JR; Shah, Vallabh O VO; Taylor, Kent D KD; Thornley-Brown, Denyse D; Zager, Philip G PG; Horvath, Amanda A; Hanson, Robert L RL; ,
Genome-wide linkage scan for prostate cancer susceptibility from the University of Michigan Prostate Cancer Genetics Project: suggestive evidence for linkage at 16q23.
The Prostate
Lange, Ethan M EM; Beebe-Dimmer, Jennifer L JL; Ray, Anna M AM; Zuhlke, Kimberly A KA; Ellis, Jaclyn J; Wang, Yunfei Y; Walters, Sarah S; Cooney, Kathleen A KA