IL17A c.27+18G>A

Variant ID: 6-52051274-G-A

NM_002190.2(IL17A):c.27+18G>A

This variant was identified in 33 publications

View GRCh38 version.




Publications:


Pharmacogenomics on the Treatment Response in Patients with Psoriasis: An Updated Review.

International Journal Of Molecular Sciences
Wang, Ching-Ya CY; Wang, Chuang-Wei CW; Chen, Chun-Bing CB; Chen, Wei-Ti WT; Chang, Ya-Ching YC; Hui, Rosaline Chung-Yee RC; Chung, Wen-Hung WH
Publication Date: 2023-04-15

Variant appearance in text: rs3819025
PubMed Link: 37108492
Variant Present in the following documents:
  • Main text
  • ijms-24-07329.pdf
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Polymorphisms in IL-17A Gene and Susceptibility of Colorectal Cancer in Bangladeshi Population: A Case-Control Analysis.

Cancer Control : Journal Of The Moffitt Cancer Center
Islam, Md Robiul MR; Aziz, Md Abdul MA; Shahriar, Mohammad M; Islam, Mohammad Safiqul MS
Publication Date: 2022

Variant appearance in text: rs3819025
PubMed Link: 36458977
Variant Present in the following documents:
  • Main text
  • 10.1177_10732748221143879.pdf
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Towards Personalized Medicine in Psoriasis: Current Progress.

Psoriasis (Auckland, N.Z.)
Camela, Elisa E; Potestio, Luca L; Ruggiero, Angelo A; Ocampo-Garza, Sonia Sofia SS; Fabbrocini, Gabriella G; Megna, Matteo M
Publication Date: 2022

Variant appearance in text: rs3819025
PubMed Link: 36071793
Variant Present in the following documents:
  • Main text
  • ptt-12-231.pdf
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Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity.

Gene
Gupta, Kajal K; Kaur, Gaganpreet G; Pathak, Tejal T; Banerjee, Indranil I
Publication Date: 2022-11-30

Variant appearance in text: rs3819025
PubMed Link: 35987511
Variant Present in the following documents:
  • Main text
  • main.pdf
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Transmembrane protease serine 2 (TMPRSS2) rs75603675, comorbidity, and sex are the primary predictors of COVID-19 severity.

Life Science Alliance
Villapalos-García, Gonzalo G; Zubiaur, Pablo P; Rivas-Durán, Rebeca R; Campos-Norte, Pilar P; Arévalo-Román, Cristina C; Fernández-Rico, Marta M; García-Fraile Fraile, Lucio L; Fernández-Campos, Paula P; Soria-Chacartegui, Paula P; Fernández de Córdoba-Oñate, Sara S; Delgado-Wicke, Pablo P; Fernández-Ruiz, Elena E; González-Álvaro, Isidoro I; Sanz, Jesús J; Abad-Santos, Francisco F; de Los Santos, Ignacio I
Publication Date: 2022-10

Variant appearance in text: rs3819025
PubMed Link: 35636966
Variant Present in the following documents:
  • Main text
  • LSA-2022-01396.pdf
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Proinflammatory Cytokines (IL-1, -6, -8, -15, -17, -18, -23, TNF-α) Single Nucleotide Polymorphisms in Rheumatoid Arthritis-A Literature Review.

International Journal Of Molecular Sciences
Koper-Lenkiewicz, Olga M OM; Sutkowska, Kinga K; Wawrusiewicz-Kurylonek, Natalia N; Kowalewska, Ewa E; Matowicka-Karna, Joanna J
Publication Date: 2022-02-14

Variant appearance in text: rs3819025
PubMed Link: 35216226
Variant Present in the following documents:
  • ijms-23-02106.pdf
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Genetic associations with immune-mediated outcomes after allogeneic hematopoietic cell transplantation.

Blood Advances
Martin, Paul J PJ; Levine, David M DM; Storer, Barry E BE; Sather, Cassandra L CL; Spellman, Stephen R SR; Hansen, John A JA
Publication Date: 2022-04-26

Variant appearance in text: rs3819025
PubMed Link: 34996099
Variant Present in the following documents:
  • advancesADV2021005620-suppl1.pdf
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Rapid and Effective Vitamin D Supplementation May Present Better Clinical Outcomes in COVID-19 (SARS-CoV-2) Patients by Altering Serum INOS1, IL1B, IFNg, Cathelicidin-LL37, and ICAM1.

Nutrients
Gönen, Mustafa Sait MS; Alaylıoğlu, Merve M; Durcan, Emre E; Özdemir, Yusuf Y; Şahin, Serdar S; Konukoğlu, Dildar D; Nohut, Okan Kadir OK; Ürkmez, Seval S; Küçükece, Berna B; Balkan, İlker İnanç İİ; Kara, H Volkan HV; Börekçi, Şermin Ş; Özkaya, Hande H; Kutlubay, Zekayi Z; Dikmen, Yalım Y; Keskindemirci, Yılmaz Y; Karras, Spyridon N SN; Annweiler, Cedric C; Gezen-Ak, Duygu D; Dursun, Erdinç E
Publication Date: 2021-11-12

Variant appearance in text: rs3819025
PubMed Link: 34836309
Variant Present in the following documents:
  • Main text
  • nutrients-13-04047.pdf
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Polymorphisms within Genes Coding for IL-17A and F and Their Receptor as Clinical Hallmarks in Ankylosing Spondylitis.

Mediators Of Inflammation
Wielińska, Joanna J; Świerkot, Jerzy J; Kolossa, Katarzyna K; Bugaj, Bartosz B; Chaszczewska-Markowska, Monika M; Jeka, Sławomir S; Bogunia-Kubik, Katarzyna K
Publication Date: 2021

Variant appearance in text: rs3819025
PubMed Link: 34744511
Variant Present in the following documents:
  • Main text
  • MI2021-3125922.pdf
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Pharmacogenomics: An Update on Biologics and Small-Molecule Drugs in the Treatment of Psoriasis.

Genes
Caputo, Valerio V; Strafella, Claudia C; Cosio, Terenzio T; Lanna, Caterina C; Campione, Elena E; Novelli, Giuseppe G; Giardina, Emiliano E; Cascella, Raffaella R
Publication Date: 2021-09-10

Variant appearance in text: rs3819025
PubMed Link: 34573380
Variant Present in the following documents:
  • Main text
  • genes-12-01398.pdf
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Lung Neutrophilic Recruitment and IL-8/IL-17A Tissue Expression in COVID-19.

Frontiers In Immunology
Azevedo, Marina Luise Viola MLV; Zanchettin, Aline Cristina AC; Vaz de Paula, Caroline Busatta CB; Motta Júnior, Jarbas da Silva JDS; Malaquias, Mineia Alessandra Scaranello MAS; Raboni, Sonia Mara SM; Neto, Plínio Cezar PC; Zeni, Rafaela Chiuco RC; Prokopenko, Amanda A; Borges, Nícolas Henrique NH; Godoy, Thiago Mateus TM; Benevides, Ana Paula Kubaski APK; de Souza, Daiane Gavlik DG; Baena, Cristina Pellegrino CP; Machado-Souza, Cleber C; de Noronha, Lucia L
Publication Date: 2021

Variant appearance in text: rs3819025
PubMed Link: 33868301
Variant Present in the following documents:
  • Main text
  • fimmu-12-656350.pdf
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Pharmacogenetics Update on Biologic Therapy in Psoriasis.

Medicina (Kaunas, Lithuania)
Muñoz-Aceituno, Ester E; Martos-Cabrera, Luisa L; Ovejero-Benito, María Carmen MC; Reolid, Alejandra A; Abad-Santos, Francisco F; Daudén, Esteban E
Publication Date: 2020-12-20

Variant appearance in text: rs3819025
PubMed Link: 33419370
Variant Present in the following documents:
  • Main text
View BVdb publication page



TH17/IL23 cytokine gene polymorphisms in bullous pemphigoid.

Molecular Genetics & Genomic Medicine
Tabatabaei-Panah, Pardis-Sadat PS; Moravvej, Hamideh H; Aghaei, Sahel S; Akbari, Maryam M; Rajabi, Sakineh S; Kia, Atena A; Ebrahimi, Elaheh E; Sadaf, Zahra Z; Atoon, Alireza A; Behravesh, Nasim N; Ludwig, Ralf J RJ; Akbarzadeh, Reza R
Publication Date: 2020-12

Variant appearance in text: rs3819025
PubMed Link: 33340282
Variant Present in the following documents:
  • Main text
  • MGG3-8-e1519.pdf
View BVdb publication page



Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition.

Bmc Genomics
Gupta, Hemant H; Chandratre, Khyati K; Sinha, Siddharth S; Huang, Teng T; Wu, Xiaobing X; Cui, Jian J; Zhang, Michael Q MQ; Wang, San Ming SM
Publication Date: 2020-11-30

Variant appearance in text: rs3819025
PubMed Link: 33256598
Variant Present in the following documents:
  • 12864_2020_7222_MOESM2_ESM.xlsx, sheet 24
  • 12864_2020_7222_MOESM2_ESM.xlsx, sheet 25
  • 12864_2020_7222_MOESM2_ESM.xlsx, sheet 27
  • 12864_2020_7222_MOESM2_ESM.xlsx, sheet 19
  • 12864_2020_7222_MOESM2_ESM.xlsx, sheet 3
  • 12864_2020_7222_MOESM2_ESM.xlsx, sheet 2
  • 12864_2020_7222_MOESM2_ESM.xlsx, sheet 4
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Psoriasis: Association of interleukin-17 gene polymorphisms with severity and response to treatment.

Experimental And Therapeutic Medicine
Pușcaș, Alexandra Dana AD; Cătană, Andreea A; Pușcaș, Cristian C; Roman, Iulia Ioana II; Vornicescu, Corina C; Șomlea, Mihaela M; Orăsan, Remus Ioan RI
Publication Date: 2019-08

Variant appearance in text: rs3819025
PubMed Link: 31384317
Variant Present in the following documents:
  • Main text
View BVdb publication page



Response to IL-17A inhibitors secukinumab and ixekizumab cannot be explained by genetic variation in the protein-coding and untranslated regions of the IL-17A gene: results from a multicentre study of four European psoriasis cohorts.

Journal Of The European Academy Of Dermatology And Venereology : Jeadv
van Vugt, L J LJ; van den Reek, J M P A JMPA; Meulewaeter, E E; Hakobjan, M M; Heddes, N N; Traks, T T; Kingo, K K; Galluzzo, M M; Talamonti, M M; Lambert, J J; Coenen, M J H MJH; de Jong, E M G J EMGJ
Publication Date: 2020-01

Variant appearance in text: rs3819025
PubMed Link: 31287604
Variant Present in the following documents:
  • Main text
  • JDV-34-112.pdf
View BVdb publication page



Genetic Evidence Supporting the Role of the Calcium Channel, CACNA1S, in Tooth Cusp and Root Patterning.

Frontiers In Physiology
Laugel-Haushalter, Virginie V; Morkmued, Supawich S; Stoetzel, Corinne C; Geoffroy, Véronique V; Muller, Jean J; Boland, Anne A; Deleuze, Jean-François JF; Chennen, Kirsley K; Pitiphat, Waranuch W; Dollfus, Hélène H; Niederreither, Karen K; Bloch-Zupan, Agnès A; Pungchanchaikul, Patimaporn P
Publication Date: 2018

Variant appearance in text: IL17A: 27+18G>A; rs3819025
PubMed Link: 30319441
Variant Present in the following documents:
  • Table_7.xlsx, sheet 1
View BVdb publication page



Associations of Common Genetic Variants on IL-17 Genes and Carotid Intima-Media Thickness.

Journal Of Atherosclerosis And Thrombosis
Wu, Tzu-Wei TW; Chou, Chao-Liang CL; Chen, Yi-Cheng YC; Juang, Yue-Li YL; Wang, Li-Yu LY
Publication Date: 2018-11-01

Variant appearance in text: rs3819025
PubMed Link: 29695654
Variant Present in the following documents:
  • Main text
View BVdb publication page



Upregulation of OLR1 and IL17A genes and their association with blood glucose and lipid levels in femoropopliteal artery disease.

Experimental And Therapeutic Medicine
Arslan, Caner C; Bayoglu, Burcu B; Tel, Cigdem C; Cengiz, Mujgan M; Dirican, Ahmet A; Besirli, Kazim K
Publication Date: 2017-03

Variant appearance in text: rs3819025
PubMed Link: 28450958
Variant Present in the following documents:
  • Main text
View BVdb publication page



A preliminary study of new single polymorphisms in the T helper type 17 pathway for psoriasis in the Korean population.

Clinical And Experimental Immunology
Kim, S Y SY; Hur, M S MS; Choi, B G BG; Kim, M J MJ; Lee, Y W YW; Choe, Y B YB; Ahn, K J KJ
Publication Date: 2017-02

Variant appearance in text: rs3819025
PubMed Link: 27774581
Variant Present in the following documents:
  • Main text
View BVdb publication page



Common variants in IL-17A/IL-17RA axis contribute to predisposition to and progression of congestive heart failure.

Medicine
Sandip, Chaugai C; Tan, Lun L; Huang, Jin J; Li, Qing Q; Ni, Li L; Cianflone, Katherine K; Wang, Dao Wen DW
Publication Date: 2016-07

Variant appearance in text: rs3819025
PubMed Link: 27399111
Variant Present in the following documents:
  • Main text
View BVdb publication page



Meta-Analysis for the Association between Polymorphisms in Interleukin-17A and Risk of Coronary Artery Disease.

International Journal Of Environmental Research And Public Health
Bao, Mei-Hua MH; Luo, Huai-Qing HQ; Xiang, Ju J; Tang, Liang L; Dong, Li-Ping LP; Li, Guang-Yi GY; Zeng, Jie J; Li, Jian-Ming JM
Publication Date: 2016-06-30

Variant appearance in text: rs3819025
PubMed Link: 27376313
Variant Present in the following documents:
  • Main text
  • ijerph-13-00660.pdf
View BVdb publication page



Genetic Analysis of IL-17 Gene Polymorphisms in Gout in a Male Chinese Han Population.

Plos One
Zhou, Zheng Z; Li, Xinde X; Li, Hua H; Guo, Mingzhen M; Liu, Shiguo S; Li, Changgui C
Publication Date: 2016

Variant appearance in text: rs3819025
PubMed Link: 26890073
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association between interleukin-17 gene polymorphisms and risk of coronary artery disease.

International Journal Of Clinical And Experimental Pathology
Shuang, Lian L; Li, Zhiliang Z; Chen, Fengying F; Cui, Xiaoying X; Ning, Yuzhen Y; Su, Youle Y; Dong, Mei M
Publication Date: 2015

Variant appearance in text: rs3819025
PubMed Link: 26617905
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Polymorphisms of IL-17F and TRAF3IP2 Could Be Predictive Factors of the Long-Term Effect of Infliximab against Crohn's Disease.

Biomed Research International
Urabe, Shigetoshi S; Isomoto, Hajime H; Ishida, Tetsuya T; Maeda, Kazumi K; Inamine, Tatsuo T; Kondo, Shinji S; Higuchi, Norihide N; Sato, Kayoko K; Uehara, Ryohei R; Yajima, Hiroyuki H; Machida, Haruhisa H; Chen, Chun Chuan CC; Fukuda, Yasuhiro Y; Takeshima, Fuminao F; Nakao, Kazuhiko K; Tsukamoto, Kazuhiro K
Publication Date: 2015

Variant appearance in text: rs3819025
PubMed Link: 26558270
Variant Present in the following documents:
  • Main text
  • BMRI2015-416838.pdf
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Association between the Interaction of Key Genes Involved in Effector T-Cell Pathways and Susceptibility to Develop allergic Rhinitis: A Population-Based Case-Control Association Study.

Plos One
Zhang, Yuan Y; Li, Jingyun J; Wang, Chengshuo C; Zhang, Luo L
Publication Date: 2015

Variant appearance in text: rs3819025
PubMed Link: 26196693
Variant Present in the following documents:
  • Main text
View BVdb publication page



Interleukin-17A gene haplotypes are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study.

Plos One
Vargas-Alarcón, Gilberto G; Angeles-Martínez, Javier J; Villarreal-Molina, Teresa T; Alvarez-León, Edith E; Posadas-Sánchez, Rosalinda R; Cardoso-Saldaña, Guillermo G; Ramírez-Bello, Julian J; Pérez-Hernández, Nonanzit N; Juárez-Rojas, Juan Gabriel JG; Rodríguez-Pérez, José Manuel JM; Fragoso, José Manuel JM; Posadas-Romero, Carlos C
Publication Date: 2015

Variant appearance in text: rs3819025
PubMed Link: 25615631
Variant Present in the following documents:
  • Main text
  • pone.0114943.pdf
View BVdb publication page



Cytokines and tumor metastasis gene variants in oral cancer and precancer in Puerto Rico.

Plos One
Erdei, Esther E; Luo, Li L; Sheng, Huiping H; Maestas, Erika E; White, Kirsten A M KA; Mackey, Amanda A; Dong, Yan Y; Berwick, Marianne M; Morse, Douglas E DE
Publication Date: 2013

Variant appearance in text: rs3819025
PubMed Link: 24278120
Variant Present in the following documents:
  • Main text
  • pone.0079187.pdf
View BVdb publication page



Association of single-nucleotide polymorphisms in the STAT3 gene with autoimmune thyroid disease in Chinese individuals.

Functional & Integrative Genomics
Xiao, Ling L; Muhali, Fatuma-Said FS; Cai, Tian-Tian TT; Song, Rong-Hua RH; Hu, Renming R; Shi, Xiao-Hong XH; Jiang, Wen-Juan WJ; Li, Dan-Feng DF; He, Shuang-Tao ST; Xu, Jian J; Zhang, Jin-An JA
Publication Date: 2013-11

Variant appearance in text: rs3819025
PubMed Link: 24081513
Variant Present in the following documents:
  • Main text
  • 10142_2013_Article_337.pdf
View BVdb publication page



Association analysis of IL-17A and IL-17F polymorphisms in Chinese Han women with breast cancer.

Plos One
Wang, Lihong L; Jiang, Yongdong Y; Zhang, Youxue Y; Wang, Yuwen Y; Huang, Sunhui S; Wang, Zhihua Z; Tian, Baoling B; Yang, Yue Y; Jiang, Wei W; Pang, Da D
Publication Date: 2012

Variant appearance in text: rs3819025
PubMed Link: 22461912
Variant Present in the following documents:
  • Main text
  • pone.0034400.pdf
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Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancer.

Cytokine
Erdei, Esther E; Kang, Huining H; Meisner, Angela A; White, Kirsten K; Pickett, Gavin G; Baca, Cynthia C; Royce, Melanie M; Berwick, Marianne M
Publication Date: 2010-07

Variant appearance in text: rs3819025
PubMed Link: 20418110
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease.

Inflammatory Bowel Diseases
McGovern, Dermot P B DP; Rotter, Jerome I JI; Mei, Ling L; Haritunians, Talin T; Landers, Carol C; Derkowski, Carrie C; Dutridge, Deb D; Dubinsky, Marla M; Ippoliti, Andy A; Vasiliauskas, Eric E; Mengesha, Emebet E; King, Lily L; Pressman, Sheila S; Targan, Stephan R SR; Taylor, Kent D KD
Publication Date: 2009-06

Variant appearance in text: rs3819025
PubMed Link: 19235914
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association analysis of the interleukin 17 genes IL17A and IL17F as potential osteoarthritis susceptibility loci.

Annals Of The Rheumatic Diseases
Southam, L L; Heath, O O; Chapman, K K; Loughlin, J J
Publication Date: 2006-04

Variant appearance in text: rs3819025
PubMed Link: 16531557
Variant Present in the following documents:
  • Main text
View BVdb publication page