Publications:

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Treatment-Resistant Schizophrenia, Clozapine Resistance, Genetic Associations, and Implications for Precision Psychiatry: A Scoping Review.

Genes

Ying, Jiangbo J; Chew, Qian Hui QH; McIntyre, Roger S RS; Sim, Kang K

Publication Date: 2023-03-10

Variant appearance in text: rs806379

PubMed Link: 36980961

Variant Present in the following documents:

• genes-14-00689.pdf

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Peripheral biomarkers of treatment-resistant schizophrenia: Genetic, inflammation and stress perspectives.

Frontiers In Pharmacology

Jiao, Shimeng S; Cao, Ting T; Cai, Hualin H

Publication Date: 2022

Variant appearance in text: rs806379

PubMed Link: 36313375

Variant Present in the following documents:

• fphar-13-1005702.pdf

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Molecular Alterations of the Endocannabinoid System in Psychiatric Disorders.

International Journal Of Molecular Sciences

Navarro, Daniela D; Gasparyan, Ani A; Navarrete, Francisco F; Torregrosa, Abraham B AB; Rubio, Gabriel G; Marín-Mayor, Marta M; Acosta, Gabriela B GB; Garcia-Gutiérrez, Maria Salud MS; Manzanares, Jorge J

Publication Date: 2022-04-26

Variant appearance in text: rs806379

PubMed Link: 35563156

Variant Present in the following documents:

• Main text
• ijms-23-04764.pdf

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Polymorphisms in Schizophrenia-Related Genes Are Potential Predictors of Antipsychotic Treatment Resistance and Refractoriness.

The International Journal Of Neuropsychopharmacology

Zazueta, Alejandra A; Castillo, Tito T; Cavieres, Álvaro Á; González, René R; Abarca, Maximiliano M; Nieto, Rodrigo R RR; Deneken, Javier J; Araneda, Cristian C; Moya, Pablo R PR; Bustamante, M Leonor ML

Publication Date: 2022-09-28

Variant appearance in text: rs806379

PubMed Link: 35416253

Variant Present in the following documents:

• Main text
• pyac025.pdf

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Biomarkers of the Endocannabinoid System in Substance Use Disorders.

Biomolecules

Navarrete, Francisco F; García-Gutiérrez, María S MS; Gasparyan, Ani A; Navarro, Daniela D; López-Picón, Francisco F; Morcuende, Álvaro Á; Femenía, Teresa T; Manzanares, Jorge J

Publication Date: 2022-03-03

Variant appearance in text: rs806379

PubMed Link: 35327588

Variant Present in the following documents:

• Main text
• biomolecules-12-00396.pdf

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Associations of CB1 cannabinoid receptor (CNR1) gene polymorphisms with risk for alcohol dependence: Evidence from meta-analyses of genetic and genome-wide association studies.

Medicine

Pabalan, Noel N; Chaweeborisuit, Phanthip P; Tharabenjasin, Phuntila P; Tasanarong, Adis A; Jarjanazi, Hamdi H; Eiamsitrakoon, Thanee T; Tapanadechopone, Pairath P

Publication Date: 2021-10-29

Variant appearance in text: rs806379

PubMed Link: 34713823

Variant Present in the following documents:

• Main text
• medi-100-e27343.pdf

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What Role Does the Endocannabinoid System Play in the Pathogenesis of Obesity?

Nutrients

Schulz, Piotr P; Hryhorowicz, Szymon S; Rychter, Anna Maria AM; Zawada, Agnieszka A; Słomski, Ryszard R; Dobrowolska, Agnieszka A; Krela-Kaźmierczak, Iwona I

Publication Date: 2021-01-26

Variant appearance in text: rs806379

PubMed Link: 33530406

Variant Present in the following documents:

• Main text

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Personality traits and polymorphisms of genes coding neurotransmitter receptors or transporters: review of single gene and genome-wide association studies.

Annals Of General Psychiatry

Zmorzyński, Szymon S; Styk, Wojciech W; Klinkosz, Waldemar W; Iskra, Justyna J; Filip, Agata Anna AA

Publication Date: 2021-01-22

Variant appearance in text: rs806379

PubMed Link: 33482861

Variant Present in the following documents:

• Main text
• 12991_2021_Article_328.pdf

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The CB1R rs2023239 receptor gene variant significantly affects the reinforcing effects of nicotine, but not cue reactivity, in human smokers.

Brain And Behavior

Chukwueke, Chidera C CC; Kowalczyk, William J WJ; Gendy, Marie M; Taylor, Richard R; Tyndale, Rachel F RF; Le Foll, Bernard B; Heishman, Stephen J SJ

Publication Date: 2021-02

Variant appearance in text: rs806379

PubMed Link: 33369277

Variant Present in the following documents:

• Main text
• BRB3-11-e01982.pdf

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Do Genes Play a Role in the Decoy Effect?

Frontiers In Psychology

Zeng, Jianmin J; Zhao, Xinyi X; Qin, Huihui H; Hou, Xingrong X; Zhang, Qinglin Q

Publication Date: 2020

Variant appearance in text: rs806379

PubMed Link: 33192763

Variant Present in the following documents:

• Main text
• fpsyg-11-523299.pdf

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Endocannabinoid System Components as Potential Biomarkers in Psychiatry.

Frontiers In Psychiatry

Navarrete, Francisco F; García-Gutiérrez, María Salud MS; Jurado-Barba, Rosa R; Rubio, Gabriel G; Gasparyan, Ani A; Austrich-Olivares, Amaya A; Manzanares, Jorge J

Publication Date: 2020

Variant appearance in text: rs806379

PubMed Link: 32395111

Variant Present in the following documents:

• Main text

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Association of a Variant of CNR1 Gene Encoding Cannabinoid Receptor 1 With Gilles de la Tourette Syndrome.

Frontiers In Genetics

Szejko, Natalia N; Fichna, Jakub Piotr JP; Safranow, Krzysztof K; Dziuba, Tomasz T; Żekanowski, Cezary C; Janik, Piotr P

Publication Date: 2020

Variant appearance in text: rs806379

PubMed Link: 32194619

Variant Present in the following documents:

• Main text
• fgene-11-00125.pdf

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Contribution of Altered Endocannabinoid System to Overactive mTORC1 Signaling in Focal Cortical Dysplasia.

Frontiers In Pharmacology

García-Rincón, Daniel D; Díaz-Alonso, Javier J; Paraíso-Luna, Juan J; Ortega, Zaira Z; Aguareles, José J; de Salas-Quiroga, Adán A; Jou, Cristina C; de Prada, Inmaculada I; Martínez-Cerdeño, Verónica V; Aronica, Eleonora E; Guzmán, Manuel M; Pérez-Jiménez, María Ángeles MÁ; Galve-Roperh, Ismael I

Publication Date: 2018

Variant appearance in text: rs806379

PubMed Link: 30687088

Variant Present in the following documents:

• Main text
• fphar-09-01508.pdf

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Association between gene polymorphisms and obesity and physical fitness in Korean children.

Biology Of Sport

Kim, Hyun Jun HJ; Lee, Sang Yeoup SY; Kim, Cheol Min CM

Publication Date: 2018-03

Variant appearance in text: rs806379

PubMed Link: 30237658

Variant Present in the following documents:

• Main text
• JBS-35-70748.pdf

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Detection of Significant Association Between Variants in Cannabinoid Receptor 1 Gene (CNR1) and Personality in African-American Population.

Frontiers In Genetics

Yao, Yinghao Y; Xu, Yi Y; Zhao, Junsheng J; Ma, Yunlong Y; Su, Kunkai K; Yuan, Wenji W; Ma, Jennie Z JZ; Payne, Thomas J TJ; Li, Ming D MD

Publication Date: 2018

Variant appearance in text: rs806379

PubMed Link: 29963071

Variant Present in the following documents:

• Main text
• fgene-09-00199.pdf

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Gene variants and educational attainment in cannabis use: mediating role of DNA methylation.

Translational Psychiatry

Gerra, Maria Carla MC; Jayanthi, Subramaniam S; Manfredini, Matteo M; Walther, Donna D; Schroeder, Jennifer J; Phillips, Karran A KA; Cadet, Jean Lud JL; Donnini, Claudia C

Publication Date: 2018-01-22

Variant appearance in text: rs806379

PubMed Link: 29353877

Variant Present in the following documents:

• Main text
• 41398_2017_Article_87.pdf

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The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data.

Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999)

Gouvêa, Eduardo S ES; Santos, Airton F AF; Ota, Vanessa K VK; Mrad, Vinicius V; Gadelha, Ary A; Bressan, Rodrigo A RA; Cordeiro, Quirino Q; Belangero, Sintia I SI

Publication Date: 2017

Variant appearance in text: rs806379

PubMed Link: 28099629

Variant Present in the following documents:

• Main text
• bjp-39-02-160.pdf

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Variants in the CNR1 gene predispose to headache with nausea in the presence of life stress.

Genes, Brain, And Behavior

Juhasz, G G; Csepany, E E; Magyar, M M; Edes, A E AE; Eszlari, N N; Hullam, G G; Antal, P P; Kokonyei, G G; Anderson, I M IM; Deakin, J F W JF; Bagdy, G G

Publication Date: 2017-03

Variant appearance in text: rs806379

PubMed Link: 27762084

Variant Present in the following documents:

• Main text
• GBB-16-384.pdf

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Genetic and Environmental Factors Associated with Cannabis Involvement.

Current Addiction Reports

Bogdan, Ryan R; Winstone, Jonathan Ma JM; Agrawal, Arpana A

Publication Date: 2016-06

Variant appearance in text: rs806379

PubMed Link: 27642547

Variant Present in the following documents:

• Main text

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Cannabinoid receptor 1 (CNR1) gene variant moderates neural index of cognitive disruption during nicotine withdrawal.

Genes, Brain, And Behavior

Evans, D E DE; Sutton, S K SK; Jentink, K G KG; Lin, H-Y HY; Park, J Y JY; Drobes, D J DJ

Publication Date: 2016-09

Variant appearance in text: rs806379

PubMed Link: 27453054

Variant Present in the following documents:

• Main text

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Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics

Lester, Kathryn J KJ; Coleman, Jonathan R I JR; Roberts, Susanna S; Keers, Robert R; Breen, Gerome G; Bögels, Susan S; Creswell, Cathy C; Hudson, Jennifer L JL; McKinnon, Anna A; Nauta, Maaike M; Rapee, Ronald M RM; Schneider, Silvia S; Silverman, Wendy K WK; Thastum, Mikael M; Waite, Polly P; Wergeland, Gro Janne H GJ; Eley, Thalia C TC

Publication Date: 2017-03

Variant appearance in text: rs806379

PubMed Link: 27346075

Variant Present in the following documents:

• Main text
• AJMG-174-144.pdf

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Longitudinal predictors of cannabis use and dependence in offspring from families at ultra high risk for alcohol dependence and in control families.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics

Hill, Shirley Y SY; Jones, Bobby L BL; Steinhauer, Stuart R SR; Zezza, Nicholas N; Stiffler, Scott S

Publication Date: 2016-04

Variant appearance in text: rs806379

PubMed Link: 26756393

Variant Present in the following documents:

• Main text

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Endocannabinoid signalling in reward and addiction.

Nature Reviews. Neuroscience

Parsons, Loren H LH; Hurd, Yasmin L YL

Publication Date: 2015-10

Variant appearance in text: rs806379

PubMed Link: 26373473

Variant Present in the following documents:

• Main text

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Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction.

Bmc Systems Biology

Reyes-Gibby, Cielito C CC; Yuan, Christine C; Wang, Jian J; Yeung, Sai-Ching J SC; Shete, Sanjay S

Publication Date: 2015-06-05

Variant appearance in text: rs806379

PubMed Link: 26044620

Variant Present in the following documents:

• Main text
• 12918_2015_Article_167.pdf

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Modulation of the endocannabinoid system: vulnerability factor and new treatment target for stimulant addiction.

Frontiers In Psychiatry

Olière, Stéphanie S; Joliette-Riopel, Antoine A; Potvin, Stéphane S; Jutras-Aswad, Didier D

Publication Date: 2013-09-23

Variant appearance in text: rs806379

PubMed Link: 24069004

Variant Present in the following documents:

• Main text
• fpsyt-04-00109.pdf

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Associations between cannabinoid receptor-1 (CNR1) variation and hippocampus and amygdala volumes in heavy cannabis users.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology

Schacht, Joseph P JP; Hutchison, Kent E KE; Filbey, Francesca M FM

Publication Date: 2012-10

Variant appearance in text: rs806379

PubMed Link: 22669173

Variant Present in the following documents:

• Main text

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Association Study of Two Cannabinoid Receptor Genes, CNR1 and CNR2, with Methamphetamine Dependence.

Current Neuropharmacology

Okahisa, Y Y; Kodama, M M; Takaki, M M; Inada, T T; Uchimura, N N; Yamada, M M; Iwata, N N; Iyo, M M; Sora, I I; Ozaki, N N; Ujike, H H

Publication Date: 2011-03

Variant appearance in text: rs806379

PubMed Link: 21886587

Variant Present in the following documents:

• Main text

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Gender-stratified gene and gene-treatment interactions in smoking cessation.

The Pharmacogenomics Journal

Lee, W W; Bergen, A W AW; Swan, G E GE; Li, D D; Liu, J J; Thomas, P P; Tyndale, R F RF; Benowitz, N L NL; Lerman, C C; Conti, D V DV

Publication Date: 2012-12

Variant appearance in text: rs806379

PubMed Link: 21808284

Variant Present in the following documents:

• NIHMS305090-supplement-3.pdf

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Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors.

Pharmacology & Therapeutics

Serrano, Antonia A; Parsons, Loren H LH

Publication Date: 2011-12

Variant appearance in text: rs806379

PubMed Link: 21798285

Variant Present in the following documents:

• Main text

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No association of candidate genes with cannabis use in a large sample of Australian twin families.

Addiction Biology

Verweij, Karin J H KJ; Zietsch, Brendan P BP; Liu, Jimmy Z JZ; Medland, Sarah E SE; Lynskey, Michael T MT; Madden, Pamela A F PA; Agrawal, Arpana A; Montgomery, Grant W GW; Heath, Andrew C AC; Martin, Nicholas G NG

Publication Date: 2012-05

Variant appearance in text: rs806379

PubMed Link: 21507154

Variant Present in the following documents:

• Main text

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Eating disorders: the current status of molecular genetic research.

European Child & Adolescent Psychiatry

Scherag, Susann S; Hebebrand, Johannes J; Hinney, Anke A

Publication Date: 2010-03

Variant appearance in text: rs806379

PubMed Link: 20033240

Variant Present in the following documents:

• Main text

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The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults.

Drug And Alcohol Dependence

Hartman, Christie A CA; Hopfer, Christian J CJ; Haberstick, Brett B; Rhee, Soo Hyun SH; Crowley, Thomas J TJ; Corley, Robin P RP; Hewitt, John K JK; Ehringer, Marissa A MA

Publication Date: 2009-09-01

Variant appearance in text: rs806379

PubMed Link: 19443135

Variant Present in the following documents:

• Main text

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Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology

Zuo, Lingjun L; Kranzler, Henry R HR; Luo, Xingguang X; Yang, Bao-zhu BZ; Weiss, Roger R; Brady, Kathleen K; Poling, James J; Farrer, Lindsay L; Gelernter, Joel J

Publication Date: 2009-05

Variant appearance in text: rs806379

PubMed Link: 19052543

Variant Present in the following documents:

• Main text

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Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa.

Child And Adolescent Psychiatry And Mental Health

Müller, Timo Dirk TD; Reichwald, Kathrin K; Brönner, Günter G; Kirschner, Jeanette J; Nguyen, Thuy Trang TT; Scherag, André A; Herzog, Wolfgang W; Herpertz-Dahlmann, Beate B; Lichtner, Peter P; Meitinger, Thomas T; Platzer, Matthias M; Schäfer, Helmut H; Hebebrand, Johannes J; Hinney, Anke A

Publication Date: 2008-11-17

Variant appearance in text: rs806379

PubMed Link: 19014633

Variant Present in the following documents:

• Main text
• 1753-2000-2-33.pdf

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Cannabinoid receptor 1 gene association with nicotine dependence.

Archives Of General Psychiatry

Chen, Xiangning X; Williamson, Vernell S VS; An, Seon-Sook SS; Hettema, John M JM; Aggen, Steven H SH; Neale, Michael C MC; Kendler, Kenneth S KS

Publication Date: 2008-07

Variant appearance in text: rs806379

PubMed Link: 18606954

Variant Present in the following documents:

• Main text

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Association study of the CNR1 gene exon 3 alternative promoter region polymorphisms and substance dependence.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics

Herman, Aryeh I AI; Kranzler, Henry R HR; Cubells, Joseph F JF; Gelernter, Joel J; Covault, Jonathan J

Publication Date: 2006-07-05

Variant appearance in text: rs806379

PubMed Link: 16741937

Variant Present in the following documents:

• Main text

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