Genes that determine immunology and inflammation modify the basic defect of impaired ion conductance in cystic fibrosis epithelia.
Journal Of Medical Genetics
Stanke, Frauke F; Becker, Tim T; Kumar, Vinod V; Hedtfeld, Silke S; Becker, Christian C; Cuppens, Harry H; Tamm, Stephanie S; Yarden, Jennifer J; Laabs, Ulrike U; Siebert, Benny B; Fernandez, Luis L; Macek, Milan M; Radojkovic, Dragica D; Ballmann, Manfred M; Greipel, Joachim J; Cassiman, Jean-Jacques JJ; Wienker, Thomas F TF; Tümmler, Burkhard B
A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+ self inhibition.
The Journal Of Physiology
Rauh, Robert R; Diakov, Alexei A; Tzschoppe, Anja A; Korbmacher, Judit J; Azad, Abul Kalam AK; Cuppens, Harry H; Cassiman, Jean-Jaques JJ; Dötsch, Jörg J; Sticht, Heinrich H; Korbmacher, Christoph C