Publications:

Structural mechanisms of CFTR function and dysfunction.

The Journal Of General Physiology

Hwang, Tzyh-Chang TC; Yeh, Jiunn-Tyng JT; Zhang, Jingyao J; Yu, Ying-Chun YC; Yeh, Han-I HI; Destefano, Samantha S

Publication Date: 2018-04-02

Variant appearance in text: CFTR: D993C

PubMed Link: 29581173

Variant Present in the following documents:

• JGP_201711946_TableS1.pdf

View BVdb publication page

Transmembrane helical interactions in the CFTR channel pore.

Plos Computational Biology

Das, Jhuma J; Aleksandrov, Andrei A AA; Cui, Liying L; He, Lihua L; Riordan, John R JR; Dokholyan, Nikolay V NV

Publication Date: 2017-06

Variant appearance in text: CFTR: D993C

PubMed Link: 28640808

Variant Present in the following documents:

• Main text
• pcbi.1005594.pdf

View BVdb publication page

Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR.

The Journal Of General Physiology

Cui, Guiying G; Rahman, Kazi S KS; Infield, Daniel T DT; Kuang, Christopher C; Prince, Chengyu Z CZ; McCarty, Nael A NA

Publication Date: 2014-08

Variant appearance in text: CFTR: D993C

PubMed Link: 25024266

Variant Present in the following documents:

• Main text
• JGP_201311122.pdf

View BVdb publication page

Two salt bridges differentially contribute to the maintenance of cystic fibrosis transmembrane conductance regulator (CFTR) channel function.

The Journal Of Biological Chemistry

Cui, Guiying G; Freeman, Cody S CS; Knotts, Taylor T; Prince, Chengyu Z CZ; Kuang, Christopher C; McCarty, Nael A NA

Publication Date: 2013-07-12

Variant appearance in text: CFTR: D993C

PubMed Link: 23709221

Variant Present in the following documents:

• Main text

View BVdb publication page