Publications:

VX-809 corrects folding defects in cystic fibrosis transmembrane conductance regulator protein through action on membrane-spanning domain 1.

Molecular Biology Of The Cell

Ren, Hong Yu HY; Grove, Diane E DE; De La Rosa, Oxana O; Houck, Scott A SA; Sopha, Pattarawut P; Van Goor, Fredrick F; Hoffman, Beth J BJ; Cyr, Douglas M DM

Publication Date: 2013-10

Variant appearance in text: CFTR: R1070A

PubMed Link: 23924900

Variant Present in the following documents:

• Main text
• 3016.pdf

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Cystic fibrosis transmembrane conductance regulator (ABCC7) structure.

Cold Spring Harbor Perspectives In Medicine

Hunt, John F JF; Wang, Chi C; Ford, Robert C RC

Publication Date: 2013-02-01

Variant appearance in text: CFTR: R1070A

PubMed Link: 23378596

Variant Present in the following documents:

• Main text

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The V510D suppressor mutation stabilizes DeltaF508-CFTR at the cell surface.

Biochemistry

Loo, Tip W TW; Bartlett, M Claire MC; Clarke, David M DM

Publication Date: 2010-08-03

Variant appearance in text: CFTR: R1070A

PubMed Link: 20590134

Variant Present in the following documents:

• Main text
• bi100807h.pdf

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