Publications:

Disease-relevant mutations alter amino acid co-evolution networks in the second nucleotide binding domain of CFTR.

Plos One

Ivey, Gabrianne G; Youker, Robert T RT

Publication Date: 2020

Variant appearance in text: CFTR: L1254A

PubMed Link: 31978131

Variant Present in the following documents:

• Main text
• pone.0227668.pdf

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ATP and AMP mutually influence their interaction with the ATP-binding cassette (ABC) adenylate kinase cystic fibrosis transmembrane conductance regulator (CFTR) at separate binding sites.

The Journal Of Biological Chemistry

Randak, Christoph O CO; Dong, Qian Q; Ver Heul, Amanda R AR; Elcock, Adrian H AH; Welsh, Michael J MJ

Publication Date: 2013-09-20

Variant appearance in text: CFTR: L1254A

PubMed Link: 23921386

Variant Present in the following documents:

• Main text
• zbc27692.pdf

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A mutation in CFTR modifies the effects of the adenylate kinase inhibitor Ap5A on channel gating.

Biophysical Journal

Dong, Qian Q; Randak, Christoph O CO; Welsh, Michael J MJ

Publication Date: 2008-12

Variant appearance in text: CFTR: L1254A

PubMed Link: 18805924

Variant Present in the following documents:

• Main text

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