Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.
Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23
Variant appearance in text: BRAF: 1799T>C; Val600Ala
Efficacy of immunotherapy for melanoma brain metastases in patients with concurrent corticosteroid exposure.
Cns Oncology
Tringale, Kathryn R KR; Reiner, Anne S AS; Sehgal, Ryka R RR; Panageas, Katherine K; Betof Warner, Allison S AS; Postow, Michael A MA; Moss, Nelson S NS
Inhibition of the Phosphatidylinositol-3 Kinase Pathway Using Bimiralisib in Loss-of-Function NOTCH1-Mutant Head and Neck Cancer.
The Oncologist
Johnson, Faye M FM; Janku, Filip F; Gouda, Mohamed A MA; Tran, Hai T HT; Kawedia, Jitesh D JD; Schmitz, Debora D; Streefkerk, Hendrik H; Lee, J Jack JJ; Andersen, Clark R CR; Deng, Defeng D; Rawal, Seema S; Shah, Pooja A PA; El-Naggar, Adel K AK; Johnson, Jason M JM; Frederick, Mitchell J MJ
Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.
Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation.
Journal For Immunotherapy Of Cancer
Wang, Minyu M; Zadeh, Soroor S; Pizzolla, Angela A; Thia, Kevin K; Gyorki, David E DE; McArthur, Grant A GA; Scolyer, Richard A RA; Long, Georgina G; Wilmott, James S JS; Andrews, Miles C MC; Au-Yeung, George G; Weppler, Ali A; Sandhu, Shahneen S; Trapani, Joseph A JA; Davis, Melissa J MJ; Neeson, Paul Joseph PJ
The GA4GH Variation Representation Specification: A computational framework for variation representation and federated identification.
Cell Genomics
Wagner, Alex H AH; Babb, Lawrence L; Alterovitz, Gil G; Baudis, Michael M; Brush, Matthew M; Cameron, Daniel L DL; Cline, Melissa M; Griffith, Malachi M; Griffith, Obi L OL; Hunt, Sarah E SE; Kreda, David D; Lee, Jennifer M JM; Li, Stephanie S; Lopez, Javier J; Moyer, Eric E; Nelson, Tristan T; Patel, Ronak Y RY; Riehle, Kevin K; Robinson, Peter N PN; Rynearson, Shawn S; Schuilenburg, Helen H; Tsukanov, Kirill K; Walsh, Brian B; Konopko, Melissa M; Rehm, Heidi L HL; Yates, Andrew D AD; Freimuth, Robert R RR; Hart, Reece K RK
Mutational landscape of circulating tumor DNA identifies distinct molecular features associated with therapeutic response in patients with metastatic colorectal cancer.
Therapeutic Advances In Medical Oncology
Shi, Min M; Yuan, Hong H; Ji, Jun J; Zhang, Shouwei S; Li, Qingyuan Q; Chen, Yawei Y; Gong, Xiaoli X; Zhu, Zhenggang Z; Zhang, Jun J
Preliminary Study on the Relationship of BRAF Mutations with the Outcome of the First 131I Radiotherapy and Malignant Biological Characteristics in Papillary Thyroid Carcinoma.
Potential benefit of treatment with MEK inhibitors and chemotherapy in BRAF-mutated KRAS wild-type pancreatic ductal adenocarcinoma patients: a case report.
Cold Spring Harbor Molecular Case Studies
Ardalan, Bach B; Azqueta, Jose Ignacio JI; England, Jonathan J; Eatz, Tiffany Alyssa TA
Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.
Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Scaffold Repurposing of In-House Small Molecule Candidates Leads to Discovery of First-in-Class CDK-1/HER-2 Dual Inhibitors: In Vitro and In Silico Screening.
Molecules (Basel, Switzerland)
Elkamhawy, Ahmed A; Ammar, Usama M UM; Paik, Sora S; Abdellattif, Magda H MH; Elsherbeny, Mohamed H MH; Lee, Kyeong K; Roh, Eun Joo EJ
Establishment and genomic characterization of a sporadic malignant peripheral nerve sheath tumor cell line.
Scientific Reports
Longo, Jody Fromm JF; Brosius, Stephanie N SN; Znoyko, Iya I; Alers, Victoria A VA; Jenkins, Dorea P DP; Wilson, Robert C RC; Carroll, Andrew J AJ; Wolff, Daynna J DJ; Roth, Kevin A KA; Carroll, Steven L SL
Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis.
British Journal Of Cancer
Bhave, Prachi P; Pallan, Lalit L; Long, Georgina V GV; Menzies, Alexander M AM; Atkinson, Victoria V; Cohen, Justine V JV; Sullivan, Ryan J RJ; Chiarion-Sileni, Vanna V; Nyakas, Marta M; Kahler, Katharina K; Hauschild, Axel A; Plummer, Ruth R; Trojaniello, Claudia C; Ascierto, Paolo A PA; Zimmer, Lisa L; Schadendorf, Dirk D; Allayous, Clara C; Lebbe, Celeste C; Maurichi, Andrea A; Santinami, Mario M; Roy, Severine S; Robert, Caroline C; Lesimple, Thierry T; Patel, Sapna S; Versluis, Judith M JM; Blank, Christian U CU; Khattak, Adnan A; Van der Westhuizen, Andre A; Carlino, Matteo S MS; Shackleton, Mark M; Haydon, Andrew A
Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis.
British Journal Of Cancer
Bhave, Prachi P; Pallan, Lalit L; Long, Georgina V GV; Menzies, Alexander M AM; Atkinson, Victoria V; Cohen, Justine V JV; Sullivan, Ryan J RJ; Chiarion-Sileni, Vanna V; Nyakas, Marta M; Kahler, Katharina K; Hauschild, Axel A; Plummer, Ruth R; Trojaniello, Claudia C; Ascierto, Paolo A PA; Zimmer, Lisa L; Schadendorf, Dirk D; Allayous, Clara C; Lebbe, Celeste C; Maurichi, Andrea A; Santinami, Mario M; Roy, Severine S; Robert, Caroline C; Lesimple, Thierry T; Patel, Sapna S; Versluis, Judith M JM; Blank, Christian U CU; Khattak, Adnan A; Van der Westhuizen, Andre A; Carlino, Matteo S MS; Shackleton, Mark M; Haydon, Andrew A
Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients.
Journal Of Clinical Medicine
Colombino, Maria M; Rozzo, Carla C; Paliogiannis, Panagiotis P; Casula, Milena M; Manca, Antonella A; Doneddu, Valentina V; Fedeli, Maria Antonietta MA; Sini, Maria Cristina MC; Palomba, Grazia G; Pisano, Marina M; Ascierto, Paolo A PA; Caracò, Corrado C; Lissia, Amelia A; Cossu, Antonio A; Palmieri, Giuseppe G
Polyacrylamide/Phytic Acid/Polydopamine Hydrogel as an Efficient Substrate for Electrochemical Enrichment of Circulating Cell-Free DNA from Blood Plasma.
Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.
Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
BRAF Exon 15 Mutations in Papillary Carcinoma and Adjacent Thyroid Parenchyma: A Search for the Early Molecular Events Associated with Tumor Development.
Cancers
Acquaviva, Giorgia G; de Biase, Dario D; Diquigiovanni, Chiara C; Argento, Chiara Maria CM; De Leo, Antonio A; Bonora, Elena E; Rhoden, Kerry Jane KJ; Pession, Annalisa A; Tallini, Giovanni G
Comparison of different semi-automated cfDNA extraction methods in combination with UMI-based targeted sequencing.
Oncotarget
Streubel, Anna A; Stenzinger, Albrecht A; Stephan-Falkenau, Susann S; Kollmeier, Jens J; Misch, Daniel D; Blum, Torsten Gerriet TG; Bauer, Torsten T; Landt, Olfert O; Am Ende, Alexander A; Schirmacher, Peter P; Mairinger, Thomas T; Endris, Volker V
Molecular alterations and PD-L1 expression in non-ampullary duodenal adenocarcinoma: Associations among clinicopathological, immunophenotypic and molecular features.
Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data.
Scientific Reports
Betancourt, Lazaro Hiram LH; Pawłowski, Krzysztof K; Eriksson, Jonatan J; Szasz, A Marcell AM; Mitra, Shamik S; Pla, Indira I; Welinder, Charlotte C; Ekedahl, Henrik H; Broberg, Per P; Appelqvist, Roger R; Yakovleva, Maria M; Sugihara, Yutaka Y; Miharada, Kenichi K; Ingvar, Christian C; Lundgren, Lotta L; Baldetorp, Bo B; Olsson, Håkan H; Rezeli, Melinda M; Wieslander, Elisabet E; Horvatovich, Peter P; Malm, Johan J; Jönsson, Göran G; Marko-Varga, György G
Polyethylene glycol improves current methods for circulating extracellular vesicle-derived DNA isolation.
Journal Of Translational Medicine
García-Romero, N N; Madurga, R R; Rackov, G G; Palacín-Aliana, I I; Núñez-Torres, R R; Asensi-Puig, A A; Carrión-Navarro, J J; Esteban-Rubio, S S; Peinado, H H; González-Neira, A A; González-Rumayor, V V; Belda-Iniesta, C C; Ayuso-Sacido, A A
Targeted mutation detection in breast cancer using MammaSeq™.
Breast Cancer Research : Bcr
Smith, Nicholas G NG; Gyanchandani, Rekha R; Shah, Osama S OS; Gurda, Grzegorz T GT; Lucas, Peter C PC; Hartmaier, Ryan J RJ; Brufsky, Adam M AM; Puhalla, Shannon S; Bahreini, Amir A; Kota, Karthik K; Wald, Abigail I AI; Nikiforov, Yuri E YE; Nikiforova, Marina N MN; Oesterreich, Steffi S; Lee, Adrian V AV
Publication Date: 2019-02-08
Variant appearance in text: BRAF: V600A; rs113488022
Distinct Molecular Profiles and Immunotherapy Treatment Outcomes of V600E and V600K BRAF-Mutant Melanoma.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Pires da Silva, Inês I; Wang, Kevin Y X KYX; Wilmott, James S JS; Holst, Jeff J; Carlino, Matteo S MS; Park, John J JJ; Quek, Camelia C; Wongchenko, Matthew M; Yan, Yibing Y; Mann, Graham G; Johnson, Douglas B DB; McQuade, Jennifer L JL; Rai, Rajat R; Kefford, Richard F RF; Rizos, Helen H; Scolyer, Richard A RA; Yang, Jean Y H JYH; Long, Georgina V GV; Menzies, Alexander M AM