Variant ID: 7-140453137-C-A

NM_004333.4(BRAF):c.1798G>T;(p.Val600Leu)

This variant was identified in 1051 publications




Publications:


Metastatic-prone telomerase reverse transcriptase (TERT) promoter and v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutated tall cell variant of papillary thyroid carcinoma arising in ectopic thyroid tissue: A case report.

Medicine
A Stenman, A Koman, C Ihre-Lundgren, CC Juhlin
Publication Date: 2021-01-15

Variant appearance in text: N/A
PubMed Link: 33466206
Variant Present in the following documents:
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Feedback activation of STAT3 limits the response to PI3K/AKT/mTOR inhibitors in PTEN-deficient cancer cells.

Oncogenesis
J Wang, X Lv, X Guo, Y Dong, P Peng, F Huang, P Wang, H Zhang, J Zhou, Y Wang, B Wei, ZF Shang, S Li
Publication Date: 2021-01-05

Variant appearance in text: N/A
PubMed Link: 33431808
Variant Present in the following documents:
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Clinical Implications of Acquired BRAF Inhibitors Resistance in Melanoma.

International Journal Of Molecular Sciences
P Savoia, E Zavattaro, O Cremona
Publication Date: 2020-12-20

Variant appearance in text: N/A
PubMed Link: 33419275
Variant Present in the following documents:
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Prevalence and Main Determinants of BRAF V600E Mutation in Dysplastic and Congenital Nevi.

Iranian Journal Of Pathology
A Ghanadan, T Yousefi, K Kamyab-Hesari, V Azhari, M Nasimi
Publication Date: 2021

Variant appearance in text: N/A
PubMed Link: 33391380
Variant Present in the following documents:
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Prognostic value of intratumoral lymphocyte-to-monocyte ratio and M0 macrophage enrichment in tumor immune microenvironment of melanoma.

Melanoma Management
NK Jairath, MW Farha, R Jairath, PW Harms, LC Tsoi, T Tejasvi
Publication Date: 2020-11-02

Variant appearance in text: N/A
PubMed Link: 33318782
Variant Present in the following documents:
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Recent advances in the management of anaplastic thyroid cancer.

Thyroid Research
S De Leo, M Trevisan, L Fugazzola
Publication Date: 2020-11-24

Variant appearance in text: N/A
PubMed Link: 33292371
Variant Present in the following documents:
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Outcomes of Treatment for Melanoma Brain Metastases.

Journal Of Skin Cancer
M Janavicius, N Lachej, G Anglickiene, I Vincerzevskiene, B Brasiuniene
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 33282420
Variant Present in the following documents:
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RAGE Signaling in Melanoma Tumors.

International Journal Of Molecular Sciences
OT Olaoba, S Kadasah, SW Vetter, E Leclerc
Publication Date: 2020-11-26

Variant appearance in text: N/A
PubMed Link: 33256110
Variant Present in the following documents:
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CDK4/6 and MAPK-Crosstalk as Opportunity for Cancer Treatment.

Pharmaceuticals (Basel, Switzerland)
L Scheiblecker, K Kollmann, V Sexl
Publication Date: 2020-11-24

Variant appearance in text: N/A
PubMed Link: 33255177
Variant Present in the following documents:
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Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.

Proceedings Of The National Academy Of Sciences Of The United States Of America
JE Mayrhofer, F Enzler, A Feichtner, R Röck, J Fleischmann, A Raffeiner, P Tschaikner, E Ogris, RG Huber, M Hartl, R Schneider, J Troppmair, O Torres-Quesada, E Stefan
Publication Date: 2020-12-08

Variant appearance in text: N/A
PubMed Link: 33229534
Variant Present in the following documents:
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Atypical UV Photoproducts Induce Non-canonical Mutation Classes Associated with Driver Mutations in Melanoma.

Cell Reports
MF Laughery, AJ Brown, KA Bohm, S Sivapragasam, HS Morris, M Tchmola, AD Washington, D Mitchell, S Mather, EP Malc, PA Mieczkowski, SA Roberts, JJ Wyrick
Publication Date: 2020-11-17

Variant appearance in text: N/A
PubMed Link: 33207206
Variant Present in the following documents:
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TP53 mutation and tumoral PD-L1 expression are associated with depth of invasion in desmoplastic melanomas.

Annals Of Translational Medicine
L Alos, C Fuster, P Castillo, P Jares, A Garcia-Herrera, M Marginet, F Agreda, A Arance, E Gonzalvo, M Garcia, S Puig, C Teixido
Publication Date: 2020-10

Variant appearance in text: N/A
PubMed Link: 33178750
Variant Present in the following documents:
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Comparative Risks of High-Grade Adverse Events Among FDA-Approved Systemic Therapies in Advanced Melanoma: Systematic Review and Network Meta-Analysis.

Frontiers In Oncology
YF Huang, WJ Xie, HY Fan, J Du
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 33178599
Variant Present in the following documents:
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Emerging agents and regimens for multiple myeloma.

Journal Of Hematology & Oncology
Y Yang, Y Li, H Gu, M Dong, Z Cai
Publication Date: 2020-11-09

Variant appearance in text: N/A
PubMed Link: 33168044
Variant Present in the following documents:
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Uveal melanoma: progress in molecular biology and therapeutics.

Therapeutic Advances In Medical Oncology
Y Li, J Shi, J Yang, S Ge, J Zhang, R Jia, X Fan
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 33149769
Variant Present in the following documents:
View BVdb publication page



Stopping targeted therapy for complete responders in advanced BRAF mutant melanoma.

Scientific Reports
L Warburton, TM Meniawy, L Calapre, M Pereira, A McEvoy, M Ziman, ES Gray, M Millward
Publication Date: 2020-11-02

Variant appearance in text: N/A
PubMed Link: 33139839
Variant Present in the following documents:
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Contemporary treatment approaches for metastatic colorectal cancer driven by BRAF V600 mutations.

World Journal Of Gastrointestinal Oncology
O Kanat, H Ertas, B Caner
Publication Date: 2020-10-15

Variant appearance in text: N/A
PubMed Link: 33133378
Variant Present in the following documents:
View BVdb publication page



Circulating tumor DNA (ctDNA) detection is associated with shorter progression-free survival in advanced melanoma patients.

Scientific Reports
GT Marczynski, AC Laus, MB Dos Reis, RM Reis, VL Vazquez
Publication Date: 2020-10-29

Variant appearance in text: N/A
PubMed Link: 33122747
Variant Present in the following documents:
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Conjunctival Melanoma: Update on Genetics, Epigenetics and Targeted Molecular and Immune-Based Therapies.

Clinical Ophthalmology (Auckland, N.Z.)
A Gkiala, S Palioura
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 33116365
Variant Present in the following documents:
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KRAS wild-type pancreatic ductal adenocarcinoma: molecular pathology and therapeutic opportunities.

Journal Of Experimental & Clinical Cancer Research : Cr
C Luchini, G Paolino, P Mattiolo, ML Piredda, A Cavaliere, M Gaule, D Melisi, R Salvia, G Malleo, JI Shin, S Cargnin, S Terrazzino, RT Lawlor, M Milella, A Scarpa
Publication Date: 2020-10-28

Variant appearance in text: N/A
PubMed Link: 33115526
Variant Present in the following documents:
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Primary cutaneous melanoma of the scalp: Patterns of clinical, histological and epidemiological characteristics in Brazil.

Plos One
AC Porto, T Pinto Blumetti, IDA Oliveira Santos Filho, VF Calsavara, JP Duprat Neto, JC Tavoloni Braga
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 33095773
Variant Present in the following documents:
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Clinical considerations about the coexistence of melanoma and chronic lymphocytic leukemia in the era of targeted therapies, triggered by rare clinical scenarios. A case series and review of the literature.

Therapeutic Advances In Medical Oncology
PT Diamantopoulos, D Ziogas, NA Viniou, A Anastasopoulou, G Kyriakakis, K Frangia, H Gogas
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 33088346
Variant Present in the following documents:
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Building a Pharmacogenomics Knowledge Model Toward Precision Medicine: Case Study in Melanoma.

Jmir Medical Informatics
H Kang, J Li, M Wu, L Shen, L Hou
Publication Date: 2020-10-21

Variant appearance in text: N/A
PubMed Link: 33084582
Variant Present in the following documents:
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Arthralgia Induced by BRAF Inhibitor Therapy in Melanoma Patients.

Cancers
M Salzmann, K Benesova, K Buder-Bakhaya, D Papamichail, A Dimitrakopoulou-Strauss, HM Lorenz, AH Enk, JC Hassel
Publication Date: 2020-10-16

Variant appearance in text: N/A
PubMed Link: 33081201
Variant Present in the following documents:
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Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients.

Scientific Reports
LG Aoude, VF Bonazzi, S Brosda, K Patel, LT Koufariotis, H Oey, K Nones, S Wood, JV Pearson, JM Lonie, M Arneil, V Atkinson, BM Smithers, N Waddell, AP Barbour
Publication Date: 2020-10-19

Variant appearance in text: N/A
PubMed Link: 33077847
Variant Present in the following documents:
View BVdb publication page



Circulating Tumor DNA Testing Opens New Perspectives in Melanoma Management.

Cancers
A Sacco, L Forgione, M Carotenuto, A Luca, PA Ascierto, G Botti, N Normanno
Publication Date: 2020-10-10

Variant appearance in text: N/A
PubMed Link: 33050536
Variant Present in the following documents:
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BRAF Alteration in Central and Peripheral Nervous System Tumors.

Frontiers In Oncology
K Srinivasa, KA Cross, S Dahiya
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 33042847
Variant Present in the following documents:
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A highly sensitive and specific real-time quantitative PCR for BRAF V600E/K mutation screening.

Scientific Reports
J Lung, MS Hung, YC Lin, YY Jiang, YH Fang, MS Lu, CC Hsieh, CS Wang, FC Kuan, CH Lu, PT Chen, CM Lin, YL Chou, CK Lin, TM Yang, FF Chen, PY Lin, MJ Hsieh, YH Tsai
Publication Date: 2020-10-09

Variant appearance in text: N/A
PubMed Link: 33037234
Variant Present in the following documents:
View BVdb publication page



Evolving impact of long-term survival results on metastatic melanoma treatment.

Journal For Immunotherapy Of Cancer
O Michielin, MB Atkins, HB Koon, R Dummer, PA Ascierto
Publication Date: 2020-10

Variant appearance in text: N/A
PubMed Link: 33037115
Variant Present in the following documents:
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BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer.

Communications Biology
F Conciatori, C Bazzichetto, CA Amoreo, I Sperduti, S Donzelli, MG Diodoro, S Buglioni, I Falcone, S Shirasawa, G Blandino, G Ferretti, F Cognetti, M Milella, L Ciuffreda
Publication Date: 2020-10-01

Variant appearance in text: N/A
PubMed Link: 33004975
Variant Present in the following documents:
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Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review.

Cancers
I Proietti, N Skroza, N Bernardini, E Tolino, V Balduzzi, A Marchesiello, S Michelini, S Volpe, A Mambrin, G Mangino, G Romeo, P Maddalena, C Rees, C Potenza
Publication Date: 2020-09-29

Variant appearance in text: N/A
PubMed Link: 33003483
Variant Present in the following documents:
View BVdb publication page



The Association of Residential Altitude on the Molecular Profile and Survival of Melanoma: Results of an Interreg Study.

Cancers
E De Martino, D Brunetti, V Canzonieri, C Conforti, K Eisendle, G Mazzoleni, C Nobile, F Rao, J Zschocke, E Jukic, W Jaschke, G Weinlich, B Zelger, M Schmuth, G Stanta, F Zanconati, I Zalaudek, S Bonin
Publication Date: 2020-09-29

Variant appearance in text: N/A
PubMed Link: 33003444
Variant Present in the following documents:
View BVdb publication page



Vemurafenib in Patients With Relapsed Refractory Multiple Myeloma Harboring BRAF V600 Mutations: A Cohort of the Histology-Independent VE-BASKET Study.

Jco Precision Oncology
N Raje, I Chau, DM Hyman, V Ribrag, JY Blay, J Tabernero, E Elez, J Wolf, AJ Yee, M Kaiser, H Landau, JM Michot, A Hollebecque, L Veronese, M Makrutzki, B Pitcher, I Puzanov, J Baselga
Publication Date: 2018

Variant appearance in text: N/A
PubMed Link: 32913989
Variant Present in the following documents:
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Phase I Study of the BRAF Inhibitor Vemurafenib in Combination With the Mammalian Target of Rapamycin Inhibitor Everolimus in Patients With BRAF-Mutated Malignancies.

Jco Precision Oncology
V Subbiah, S Sen, KR Hess, F Janku, DS Hong, S Khatua, DD Karp, J Munoz, GS Falchook, R Groisberg, AM Tsimberidou, SI Sherman, P Hwu, F Meric-Bernstam
Publication Date: 2018

Variant appearance in text: N/A
PubMed Link: 32913986
Variant Present in the following documents:
View BVdb publication page



Detection of BRAF V600E Mutation in Ganglioglioma and Pilocytic Astrocytoma by Immunohistochemistry and Real-Time PCR-Based Idylla Test.

Disease Markers
J Durślewicz, A Klimaszewska-Wiśniewska, P Antosik, A Kasperska, D Grzanka, T Szylberg, Ł Szylberg
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32879641
Variant Present in the following documents:
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Necrotizing myositis in a rectus muscle arising in the setting of long-standing Langerhans cell histiocystosis and recent dabrafenib treatment.

American Journal Of Ophthalmology Case Reports
SW van Landingham, D Puccetti, H Potter, D Gamm, EL Diamond, MJ Lucarelli
Publication Date: 2020-12

Variant appearance in text: N/A
PubMed Link: 32875153
Variant Present in the following documents:
View BVdb publication page



Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases.

Nature Communications
R Rabbie, N Ansari-Pour, O Cast, D Lau, F Scott, SJ Welsh, C Parkinson, L Khoja, L Moore, M Tullett, K Wong, I Ferreira, JMM Gómez, M Levesque, FA Gallagher, A Jiménez-Sánchez, L Riva, ML Miller, K Allinson, PJ Campbell, P Corrie, DC Wedge, DJ Adams
Publication Date: 2020-08-27

Variant appearance in text: N/A
PubMed Link: 32855398
Variant Present in the following documents:
View BVdb publication page



Non-BRAF Mutant Melanoma: Molecular Features and Therapeutical Implications.

Frontiers In Molecular Biosciences
I Vanni, ET Tanda, B Dalmasso, L Pastorino, V Andreotti, W Bruno, A Boutros, F Spagnolo, P Ghiorzo
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32850962
Variant Present in the following documents:
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Uncommon Subtypes of Malignant Melanomas: A Review Based on Clinical and Molecular Perspectives.

Cancers
M Chacón, Y Pfluger, M Angel, F Waisberg, D Enrico
Publication Date: 2020-08-21

Variant appearance in text: N/A
PubMed Link: 32825562
Variant Present in the following documents:
View BVdb publication page



Real World Outcomes of Ipilimumab and Nivolumab in Patients with Metastatic Melanoma.

Cancers
N Asher, G Ben-Betzalel, S Lev-Ari, R Shapira-Frommer, Y Steinberg-Silman, N Gochman, J Schachter, T Meirson, G Markel
Publication Date: 2020-08-18

Variant appearance in text: N/A
PubMed Link: 32824780
Variant Present in the following documents:
View BVdb publication page



MILO/ENGOT-ov11: Binimetinib Versus Physician's Choice Chemotherapy in Recurrent or Persistent Low-Grade Serous Carcinomas of the Ovary, Fallopian Tube, or Primary Peritoneum.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
BJ Monk, RN Grisham, S Banerjee, E Kalbacher, MR Mirza, I Romero, P Vuylsteke, RL Coleman, F Hilpert, AM Oza, A Westermann, MK Oehler, S Pignata, C Aghajanian, N Colombo, E Drill, D Cibula, KN Moore, J Christy-Bittel, JM Del Campo, R Berger, C Marth, J Sehouli, DM O'Malley, C Churruca, AP Boyd, G Kristensen, A Clamp, I Ray-Coquard, I Vergote
Publication Date: 2020-11-10

Variant appearance in text: N/A
PubMed Link: 32822286
Variant Present in the following documents:
View BVdb publication page



Melanoma brain metastases: review of histopathological features and immune-molecular aspects.

Melanoma Management
L Salvati, M Mandalà, D Massi
Publication Date: 2020-06-08

Variant appearance in text: N/A
PubMed Link: 32821376
Variant Present in the following documents:
View BVdb publication page



Risk factors for MEK-associated retinopathy in patients with advanced melanoma treated with combination BRAF and MEK inhibitor therapy.

Therapeutic Advances In Medical Oncology
AEC Booth, AM Hopkins, A Rowland, G Kichenadasse, JR Smith, MJ Sorich
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32821295
Variant Present in the following documents:
View BVdb publication page



Targeting Mutant KRAS in Pancreatic Cancer: Futile or Promising?

Biomedicines
FI Nollmann, DA Ruess
Publication Date: 2020-08-11

Variant appearance in text: N/A
PubMed Link: 32796566
Variant Present in the following documents:
View BVdb publication page



BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation.

Oncogene
N Reischmann, G Andrieux, R Griffin, T Reinheckel, M Boerries, T Brummer
Publication Date: 2020-09

Variant appearance in text: N/A
PubMed Link: 32792685
Variant Present in the following documents:
View BVdb publication page



TERT Promoter Mutation as an Independent Prognostic Marker for Poor Prognosis MAPK Inhibitors-Treated Melanoma.

Cancers
P Blateau, E Coyaud, E Laurent, B Béganton, V Ducros, G Chauchard, JA Vendrell, J Solassol
Publication Date: 2020-08-09

Variant appearance in text: N/A
PubMed Link: 32784823
Variant Present in the following documents:
View BVdb publication page



Photochemical and Photobiological Properties of Pyridyl-pyrazol(in)e-Based Ruthenium(II) Complexes with Sub-micromolar Cytotoxicity for Phototherapy.

Acs Omega
D Havrylyuk, DK Heidary, Y Sun, S Parkin, EC Glazer
Publication Date: 2020-08-04

Variant appearance in text: N/A
PubMed Link: 32775891
Variant Present in the following documents:
View BVdb publication page



Mutations in the BRAF, NRAS, and C-KIT Genes of Patients Diagnosed with Melanoma in Colombia Population.

Biomed Research International
LD Gutiérrez-Castañeda, M Gamboa, JA Nova, L Pulido, JD Tovar-Parra
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32775409
Variant Present in the following documents:
View BVdb publication page



Primary Melanoma of the Lung Treated with Surgery, Dabrafenib and Trametinib.

Case Reports In Oncology
LG Landgraf, MA Malias, SJ Patterson
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32774277
Variant Present in the following documents:
View BVdb publication page



Current State of Target Treatment in BRAF Mutated Melanoma.

Frontiers In Molecular Biosciences
ET Tanda, I Vanni, A Boutros, V Andreotti, W Bruno, P Ghiorzo, F Spagnolo
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32760738
Variant Present in the following documents:
View BVdb publication page



Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients.

Journal Of Clinical Medicine
M Colombino, C Rozzo, P Paliogiannis, M Casula, A Manca, V Doneddu, MA Fedeli, MC Sini, G Palomba, M Pisano, PA Ascierto, C Caracò, A Lissia, A Cossu, G Palmieri
Publication Date: 2020-07-30

Variant appearance in text: N/A
PubMed Link: 32751423
Variant Present in the following documents:
View BVdb publication page



Personalized Treatment Selection and Disease Monitoring Using Circulating Tumor DNA Profiling in Real-World Cancer Patient Management.

Diagnostics (Basel, Switzerland)
J Wehrle, U Philipp, M Jolic, M Follo, S Hussung, S Waldeck, M Deuter, M Rassner, J Braune, J Rawluk, C Greil, CF Waller, H Becker, J Duque-Afonso, AL Illert, RM Fritsch, F Meiss, J Duyster, N von Bubnoff, F Scherer
Publication Date: 2020-08-02

Variant appearance in text: N/A
PubMed Link: 32748806
Variant Present in the following documents:
View BVdb publication page



Plasmacytoid Dendritic Cell Impairment in Metastatic Melanoma by Lactic Acidosis.

Cancers
M Monti, R Vescovi, F Consoli, D Farina, D Moratto, A Berruti, C Specchia, W Vermi
Publication Date: 2020-07-28

Variant appearance in text: N/A
PubMed Link: 32731406
Variant Present in the following documents:
View BVdb publication page



Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response.

Cancers
MK van der Kooij, MJAL Wetzels, MJB Aarts, FWPJ van den Berkmortel, CU Blank, MJ Boers-Sonderen, MP Dierselhuis, JWB de Groot, GAP Hospers, D Piersma, RS van Rijn, KPM Suijkerbuijk, AJ Ten Tije, AAM van der Veldt, G Vreugdenhil, MWJM Wouters, JBAG Haanen, AJM van den Eertwegh, E Bastiaannet, E Kapiteijn
Publication Date: 2020-07-27

Variant appearance in text: N/A
PubMed Link: 32726988
Variant Present in the following documents:
View BVdb publication page



Genetic Biomarkers in Melanoma of the Ocular Region: What the Medical Oncologist Should Know.

International Journal Of Molecular Sciences
KF Bol, M Donia, S Heegaard, JF Kiilgaard, IM Svane
Publication Date: 2020-07-23

Variant appearance in text: N/A
PubMed Link: 32718045
Variant Present in the following documents:
View BVdb publication page



Ultraviolet Radiation and Melanomagenesis: From Mechanism to Immunotherapy.

Frontiers In Oncology
X Sun, N Zhang, C Yin, B Zhu, X Li
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32714859
Variant Present in the following documents:
View BVdb publication page



The Roles of Common Variation and Somatic Mutation in Cancer Pharmacogenomics.

Oncology And Therapy
HT Chan, YM Chin, SK Low
Publication Date: 2019-06

Variant appearance in text: N/A
PubMed Link: 32700193
Variant Present in the following documents:
View BVdb publication page



The Current State of Molecular Testing in the BRAF-Mutated Melanoma Landscape.

Frontiers In Molecular Biosciences
I Vanni, ET Tanda, F Spagnolo, V Andreotti, W Bruno, P Ghiorzo
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32695793
Variant Present in the following documents:
View BVdb publication page



Spontaneous Regression of Primary Melanoma and Multiple Melanocytic Nevi in a Patient With Metastatic Melanoma.

Dermatology Practical & Conceptual
G Paolino, N Rizzo, R Pampena, P Bearzi, A Bulotta, V Gregorc, P Brianti, E Moliterni, SR Mercuri
Publication Date: 2020-07

Variant appearance in text: N/A
PubMed Link: 32685272
Variant Present in the following documents:
View BVdb publication page



Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions.

Journal Of Immunology Research
M Ralli, A Botticelli, IC Visconti, D Angeletti, M Fiore, P Marchetti, A Lambiase, M de Vincentiis, A Greco
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32671117
Variant Present in the following documents:
View BVdb publication page



Current and Future Role of Tyrosine Kinases Inhibition in Thyroid Cancer: From Biology to Therapy.

International Journal Of Molecular Sciences
M San Román Gil, J Pozas, J Molina-Cerrillo, J Gómez, H Pian, M Pozas, A Carrato, E Grande, T Alonso-Gordoa
Publication Date: 2020-07-13

Variant appearance in text: N/A
PubMed Link: 32668761
Variant Present in the following documents:
View BVdb publication page



Circulating Tumour DNA Is an Independent Prognostic Biomarker for Survival in Metastatic BRAF or NRAS-Mutated Melanoma Patients.

Cancers
G Herbreteau, A Vallée, AC Knol, S Théoleyre, G Quéreux, C Frénard, E Varey, P Hofman, A Khammari, B Dréno, MG Denis
Publication Date: 2020-07-11

Variant appearance in text: N/A
PubMed Link: 32664549
Variant Present in the following documents:
View BVdb publication page



Toxicity of combined targeted therapy and concurrent radiotherapy in metastatic melanoma patients: a single-center retrospective analysis.

Melanoma Research
JS Ziegler, S Kroeze, ML Hilbers, L Imhof, M Guckenberger, MP Levesque, R Dummer, P Cheng, J Mangana
Publication Date: 2020-12

Variant appearance in text: N/A
PubMed Link: 32658050
Variant Present in the following documents:
View BVdb publication page



Clinical Relevance of BRAF V600E Mutation Status in Brain Tumors with a Focus on a Novel Management Algorithm.

Targeted Oncology
A Kowalewski, J Durślewicz, M Zdrenka, D Grzanka, Ł Szylberg
Publication Date: 2020-08

Variant appearance in text: N/A
PubMed Link: 32648041
Variant Present in the following documents:
View BVdb publication page



BRAF Inhibitors: Molecular Targeting and Immunomodulatory Actions.

Cancers
I Proietti, N Skroza, S Michelini, A Mambrin, V Balduzzi, N Bernardini, A Marchesiello, E Tolino, S Volpe, P Maddalena, M Di Fraia, G Mangino, G Romeo, C Potenza
Publication Date: 2020-07-07

Variant appearance in text: N/A
PubMed Link: 32645969
Variant Present in the following documents:
View BVdb publication page



Characterization of Class-3 Semaphorin Receptors, Neuropilins and Plexins, as Therapeutic Targets in a Pan-Cancer Study.

Cancers
X Zhang, S Shao, L Li
Publication Date: 2020-07-06

Variant appearance in text: N/A
PubMed Link: 32640719
Variant Present in the following documents:
View BVdb publication page



The Potential of Tumor Debulking to Support Molecular Targeted Therapies.

Frontiers In Oncology
F Oppel, M Görner, H Sudhoff
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32626653
Variant Present in the following documents:
View BVdb publication page



Optimal treatment strategy for metastatic melanoma patients harboring BRAF-V600 mutations.

Therapeutic Advances In Medical Oncology
EF Giunta, V De Falco, S Napolitano, G Argenziano, G Brancaccio, E Moscarella, D Ciardiello, F Ciardiello, T Troiani
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32612709
Variant Present in the following documents:
View BVdb publication page



Cytotoxic Effect of Vanicosides A and B from Reynoutria sachalinensis Against Melanotic and Amelanotic Melanoma Cell Lines and in silico Evaluation for Inhibition of BRAFV600E and MEK1.

International Journal Of Molecular Sciences
I Nawrot-Hadzik, A Choromańska, R Abel, R Preissner, J Saczko, A Matkowski, J Hadzik
Publication Date: 2020-06-29

Variant appearance in text: N/A
PubMed Link: 32610527
Variant Present in the following documents:
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Targeted Therapy in Melanoma and Mechanisms of Resistance.

International Journal Of Molecular Sciences
AM Czarnecka, E Bartnik, M Fiedorowicz, P Rutkowski
Publication Date: 2020-06-27

Variant appearance in text: N/A
PubMed Link: 32605090
Variant Present in the following documents:
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KRAS and BRAF Concomitant Mutations in a Patient with Metastatic Colon Adenocarcinoma: An Interesting Case Report.

Case Reports In Oncology
C Cafiero, A Re, G D'Amato, PL Surico, G Surico, M Pirrelli, S Pisconti
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32595468
Variant Present in the following documents:
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Circulating Tumor DNA Correlates with Outcome in Metastatic Melanoma Treated by BRAF and MEK Inhibitors - Results of a Prospective Biomarker Study.

Oncotargets And Therapy
A Forschner, S Weißgraeber, D Hadaschik, M Schulze, M Kopp, S Kelkenberg, T Sinnberg, C Garbe, S Biskup, F Battke
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32581559
Variant Present in the following documents:
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Calcium-sensing receptor autoantibody-mediated hypoparathyroidism associated with immune checkpoint inhibitor therapy: diagnosis and long-term follow-up.

Journal For Immunotherapy Of Cancer
R Dadu, TE Rodgers, VA Trinh, EH Kemp, TD Cubb, S Patel, JM Simon, EM Burton, H Tawbi
Publication Date: 2020-06

Variant appearance in text: N/A
PubMed Link: 32581059
Variant Present in the following documents:
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Melanoma Brain Metastases in the Era of Target Therapies: An Overview.

Cancers
P Becco, S Gallo, S Poletto, MPM Frascione, L Crotto, A Zaccagna, L Paruzzo, D Caravelli, F Carnevale-Schianca, M Aglietta
Publication Date: 2020-06-21

Variant appearance in text: N/A
PubMed Link: 32575838
Variant Present in the following documents:
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The Evolution of Care of Cancers of the Head and Neck Region: State of the Science in 2020.

Cancers
F Yan, HM Knochelmann, PF Morgan, JM Kaczmar, DM Neskey, EM Graboyes, SA Nguyen, B Ogretmen, AK Sharma, TA Day
Publication Date: 2020-06-11

Variant appearance in text: N/A
PubMed Link: 32545409
Variant Present in the following documents:
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Integration of Digital Pathologic and Transcriptomic Analyses Connects Tumor-Infiltrating Lymphocyte Spatial Density With Clinical Response to BRAF Inhibitors.

Frontiers In Oncology
A Ziemys, M Kim, AM Menzies, JS Wilmott, GV Long, RA Scolyer, L Kwong, A Holder, G Boland
Publication Date: 2020

Variant appearance in text: N/A
PubMed Link: 32528881
Variant Present in the following documents:
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000288602.6 c.1798G>T p.Val600Leu missense_variant 15/18 -
ENST00000479537.1 c.82G>T p.Val28Leu missense_variant,NMD_transcript_variant 2/6 -
ENST00000496384.2 c.622G>T p.Val208Leu missense_variant 6/10 -
ENST00000497784.1 c.*1248G>T - 3_prime_UTR_variant,NMD_transcript_variant 16/19 -
NM_001354609.2 c.1798G>T p.Val600Leu missense_variant 15/19 -
NM_004333.6 c.1798G>T p.Val600Leu missense_variant 15/18 -
NR_148928.2 n.2897G>T - non_coding_transcript_exon_variant 15/18 -