Publications:

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Metastatic-prone telomerase reverse transcriptase (TERT) promoter and v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutated tall cell variant of papillary thyroid carcinoma arising in ectopic thyroid tissue: A case report.

Medicine

A Stenman, A Koman, C Ihre-Lundgren, CC Juhlin

Publication Date: 2021-01-15

Variant appearance in text: N/A

PubMed Link: 33466206

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Feedback activation of STAT3 limits the response to PI3K/AKT/mTOR inhibitors in PTEN-deficient cancer cells.

Oncogenesis

J Wang, X Lv, X Guo, Y Dong, P Peng, F Huang, P Wang, H Zhang, J Zhou, Y Wang, B Wei, ZF Shang, S Li

Publication Date: 2021-01-05

Variant appearance in text: N/A

PubMed Link: 33431808

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Clinical Implications of Acquired BRAF Inhibitors Resistance in Melanoma.

International Journal Of Molecular Sciences

P Savoia, E Zavattaro, O Cremona

Publication Date: 2020-12-20

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PubMed Link: 33419275

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Prevalence and Main Determinants of BRAF V600E Mutation in Dysplastic and Congenital Nevi.

Iranian Journal Of Pathology

A Ghanadan, T Yousefi, K Kamyab-Hesari, V Azhari, M Nasimi

Publication Date: 2021

Variant appearance in text: N/A

PubMed Link: 33391380

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Prognostic value of intratumoral lymphocyte-to-monocyte ratio and M0 macrophage enrichment in tumor immune microenvironment of melanoma.

Melanoma Management

NK Jairath, MW Farha, R Jairath, PW Harms, LC Tsoi, T Tejasvi

Publication Date: 2020-11-02

Variant appearance in text: N/A

PubMed Link: 33318782

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Recent advances in the management of anaplastic thyroid cancer.

Thyroid Research

S De Leo, M Trevisan, L Fugazzola

Publication Date: 2020-11-24

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PubMed Link: 33292371

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Outcomes of Treatment for Melanoma Brain Metastases.

Journal Of Skin Cancer

M Janavicius, N Lachej, G Anglickiene, I Vincerzevskiene, B Brasiuniene

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 33282420

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RAGE Signaling in Melanoma Tumors.

International Journal Of Molecular Sciences

OT Olaoba, S Kadasah, SW Vetter, E Leclerc

Publication Date: 2020-11-26

Variant appearance in text: N/A

PubMed Link: 33256110

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CDK4/6 and MAPK-Crosstalk as Opportunity for Cancer Treatment.

Pharmaceuticals (Basel, Switzerland)

L Scheiblecker, K Kollmann, V Sexl

Publication Date: 2020-11-24

Variant appearance in text: N/A

PubMed Link: 33255177

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Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.

Proceedings Of The National Academy Of Sciences Of The United States Of America

JE Mayrhofer, F Enzler, A Feichtner, R Röck, J Fleischmann, A Raffeiner, P Tschaikner, E Ogris, RG Huber, M Hartl, R Schneider, J Troppmair, O Torres-Quesada, E Stefan

Publication Date: 2020-12-08

Variant appearance in text: N/A

PubMed Link: 33229534

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Atypical UV Photoproducts Induce Non-canonical Mutation Classes Associated with Driver Mutations in Melanoma.

Cell Reports

MF Laughery, AJ Brown, KA Bohm, S Sivapragasam, HS Morris, M Tchmola, AD Washington, D Mitchell, S Mather, EP Malc, PA Mieczkowski, SA Roberts, JJ Wyrick

Publication Date: 2020-11-17

Variant appearance in text: N/A

PubMed Link: 33207206

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TP53 mutation and tumoral PD-L1 expression are associated with depth of invasion in desmoplastic melanomas.

Annals Of Translational Medicine

L Alos, C Fuster, P Castillo, P Jares, A Garcia-Herrera, M Marginet, F Agreda, A Arance, E Gonzalvo, M Garcia, S Puig, C Teixido

Publication Date: 2020-10

Variant appearance in text: N/A

PubMed Link: 33178750

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Comparative Risks of High-Grade Adverse Events Among FDA-Approved Systemic Therapies in Advanced Melanoma: Systematic Review and Network Meta-Analysis.

Frontiers In Oncology

YF Huang, WJ Xie, HY Fan, J Du

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 33178599

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Emerging agents and regimens for multiple myeloma.

Journal Of Hematology & Oncology

Y Yang, Y Li, H Gu, M Dong, Z Cai

Publication Date: 2020-11-09

Variant appearance in text: N/A

PubMed Link: 33168044

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Uveal melanoma: progress in molecular biology and therapeutics.

Therapeutic Advances In Medical Oncology

Y Li, J Shi, J Yang, S Ge, J Zhang, R Jia, X Fan

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 33149769

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Stopping targeted therapy for complete responders in advanced BRAF mutant melanoma.

Scientific Reports

L Warburton, TM Meniawy, L Calapre, M Pereira, A McEvoy, M Ziman, ES Gray, M Millward

Publication Date: 2020-11-02

Variant appearance in text: N/A

PubMed Link: 33139839

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Contemporary treatment approaches for metastatic colorectal cancer driven by BRAF V600 mutations.

World Journal Of Gastrointestinal Oncology

O Kanat, H Ertas, B Caner

Publication Date: 2020-10-15

Variant appearance in text: N/A

PubMed Link: 33133378

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Circulating tumor DNA (ctDNA) detection is associated with shorter progression-free survival in advanced melanoma patients.

Scientific Reports

GT Marczynski, AC Laus, MB Dos Reis, RM Reis, VL Vazquez

Publication Date: 2020-10-29

Variant appearance in text: N/A

PubMed Link: 33122747

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Conjunctival Melanoma: Update on Genetics, Epigenetics and Targeted Molecular and Immune-Based Therapies.

Clinical Ophthalmology (Auckland, N.Z.)

A Gkiala, S Palioura

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 33116365

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KRAS wild-type pancreatic ductal adenocarcinoma: molecular pathology and therapeutic opportunities.

Journal Of Experimental & Clinical Cancer Research : Cr

C Luchini, G Paolino, P Mattiolo, ML Piredda, A Cavaliere, M Gaule, D Melisi, R Salvia, G Malleo, JI Shin, S Cargnin, S Terrazzino, RT Lawlor, M Milella, A Scarpa

Publication Date: 2020-10-28

Variant appearance in text: N/A

PubMed Link: 33115526

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Primary cutaneous melanoma of the scalp: Patterns of clinical, histological and epidemiological characteristics in Brazil.

Plos One

AC Porto, T Pinto Blumetti, IDA Oliveira Santos Filho, VF Calsavara, JP Duprat Neto, JC Tavoloni Braga

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 33095773

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Clinical considerations about the coexistence of melanoma and chronic lymphocytic leukemia in the era of targeted therapies, triggered by rare clinical scenarios. A case series and review of the literature.

Therapeutic Advances In Medical Oncology

PT Diamantopoulos, D Ziogas, NA Viniou, A Anastasopoulou, G Kyriakakis, K Frangia, H Gogas

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 33088346

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Building a Pharmacogenomics Knowledge Model Toward Precision Medicine: Case Study in Melanoma.

Jmir Medical Informatics

H Kang, J Li, M Wu, L Shen, L Hou

Publication Date: 2020-10-21

Variant appearance in text: N/A

PubMed Link: 33084582

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Arthralgia Induced by BRAF Inhibitor Therapy in Melanoma Patients.

Cancers

M Salzmann, K Benesova, K Buder-Bakhaya, D Papamichail, A Dimitrakopoulou-Strauss, HM Lorenz, AH Enk, JC Hassel

Publication Date: 2020-10-16

Variant appearance in text: N/A

PubMed Link: 33081201

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Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients.

Scientific Reports

LG Aoude, VF Bonazzi, S Brosda, K Patel, LT Koufariotis, H Oey, K Nones, S Wood, JV Pearson, JM Lonie, M Arneil, V Atkinson, BM Smithers, N Waddell, AP Barbour

Publication Date: 2020-10-19

Variant appearance in text: N/A

PubMed Link: 33077847

Variant Present in the following documents:

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Circulating Tumor DNA Testing Opens New Perspectives in Melanoma Management.

Cancers

A Sacco, L Forgione, M Carotenuto, A Luca, PA Ascierto, G Botti, N Normanno

Publication Date: 2020-10-10

Variant appearance in text: N/A

PubMed Link: 33050536

Variant Present in the following documents:

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BRAF Alteration in Central and Peripheral Nervous System Tumors.

Frontiers In Oncology

K Srinivasa, KA Cross, S Dahiya

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 33042847

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A highly sensitive and specific real-time quantitative PCR for BRAF V600E/K mutation screening.

Scientific Reports

J Lung, MS Hung, YC Lin, YY Jiang, YH Fang, MS Lu, CC Hsieh, CS Wang, FC Kuan, CH Lu, PT Chen, CM Lin, YL Chou, CK Lin, TM Yang, FF Chen, PY Lin, MJ Hsieh, YH Tsai

Publication Date: 2020-10-09

Variant appearance in text: N/A

PubMed Link: 33037234

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Evolving impact of long-term survival results on metastatic melanoma treatment.

Journal For Immunotherapy Of Cancer

O Michielin, MB Atkins, HB Koon, R Dummer, PA Ascierto

Publication Date: 2020-10

Variant appearance in text: N/A

PubMed Link: 33037115

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BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer.

Communications Biology

F Conciatori, C Bazzichetto, CA Amoreo, I Sperduti, S Donzelli, MG Diodoro, S Buglioni, I Falcone, S Shirasawa, G Blandino, G Ferretti, F Cognetti, M Milella, L Ciuffreda

Publication Date: 2020-10-01

Variant appearance in text: N/A

PubMed Link: 33004975

Variant Present in the following documents:

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Mechanisms of Acquired BRAF Inhibitor Resistance in Melanoma: A Systematic Review.

Cancers

I Proietti, N Skroza, N Bernardini, E Tolino, V Balduzzi, A Marchesiello, S Michelini, S Volpe, A Mambrin, G Mangino, G Romeo, P Maddalena, C Rees, C Potenza

Publication Date: 2020-09-29

Variant appearance in text: N/A

PubMed Link: 33003483

Variant Present in the following documents:

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The Association of Residential Altitude on the Molecular Profile and Survival of Melanoma: Results of an Interreg Study.

Cancers

E De Martino, D Brunetti, V Canzonieri, C Conforti, K Eisendle, G Mazzoleni, C Nobile, F Rao, J Zschocke, E Jukic, W Jaschke, G Weinlich, B Zelger, M Schmuth, G Stanta, F Zanconati, I Zalaudek, S Bonin

Publication Date: 2020-09-29

Variant appearance in text: N/A

PubMed Link: 33003444

Variant Present in the following documents:

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Vemurafenib in Patients With Relapsed Refractory Multiple Myeloma Harboring BRAF V600 Mutations: A Cohort of the Histology-Independent VE-BASKET Study.

Jco Precision Oncology

N Raje, I Chau, DM Hyman, V Ribrag, JY Blay, J Tabernero, E Elez, J Wolf, AJ Yee, M Kaiser, H Landau, JM Michot, A Hollebecque, L Veronese, M Makrutzki, B Pitcher, I Puzanov, J Baselga

Publication Date: 2018

Variant appearance in text: N/A

PubMed Link: 32913989

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Phase I Study of the BRAF Inhibitor Vemurafenib in Combination With the Mammalian Target of Rapamycin Inhibitor Everolimus in Patients With BRAF-Mutated Malignancies.

Jco Precision Oncology

V Subbiah, S Sen, KR Hess, F Janku, DS Hong, S Khatua, DD Karp, J Munoz, GS Falchook, R Groisberg, AM Tsimberidou, SI Sherman, P Hwu, F Meric-Bernstam

Publication Date: 2018

Variant appearance in text: N/A

PubMed Link: 32913986

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Detection of BRAF V600E Mutation in Ganglioglioma and Pilocytic Astrocytoma by Immunohistochemistry and Real-Time PCR-Based Idylla Test.

Disease Markers

J Durślewicz, A Klimaszewska-Wiśniewska, P Antosik, A Kasperska, D Grzanka, T Szylberg, Ł Szylberg

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32879641

Variant Present in the following documents:

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Necrotizing myositis in a rectus muscle arising in the setting of long-standing Langerhans cell histiocystosis and recent dabrafenib treatment.

American Journal Of Ophthalmology Case Reports

SW van Landingham, D Puccetti, H Potter, D Gamm, EL Diamond, MJ Lucarelli

Publication Date: 2020-12

Variant appearance in text: N/A

PubMed Link: 32875153

Variant Present in the following documents:

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Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases.

Nature Communications

R Rabbie, N Ansari-Pour, O Cast, D Lau, F Scott, SJ Welsh, C Parkinson, L Khoja, L Moore, M Tullett, K Wong, I Ferreira, JMM Gómez, M Levesque, FA Gallagher, A Jiménez-Sánchez, L Riva, ML Miller, K Allinson, PJ Campbell, P Corrie, DC Wedge, DJ Adams

Publication Date: 2020-08-27

Variant appearance in text: N/A

PubMed Link: 32855398

Variant Present in the following documents:

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Non-BRAF Mutant Melanoma: Molecular Features and Therapeutical Implications.

Frontiers In Molecular Biosciences

I Vanni, ET Tanda, B Dalmasso, L Pastorino, V Andreotti, W Bruno, A Boutros, F Spagnolo, P Ghiorzo

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32850962

Variant Present in the following documents:

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Uncommon Subtypes of Malignant Melanomas: A Review Based on Clinical and Molecular Perspectives.

Cancers

M Chacón, Y Pfluger, M Angel, F Waisberg, D Enrico

Publication Date: 2020-08-21

Variant appearance in text: N/A

PubMed Link: 32825562

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Real World Outcomes of Ipilimumab and Nivolumab in Patients with Metastatic Melanoma.

Cancers

N Asher, G Ben-Betzalel, S Lev-Ari, R Shapira-Frommer, Y Steinberg-Silman, N Gochman, J Schachter, T Meirson, G Markel

Publication Date: 2020-08-18

Variant appearance in text: N/A

PubMed Link: 32824780

Variant Present in the following documents:

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MILO/ENGOT-ov11: Binimetinib Versus Physician's Choice Chemotherapy in Recurrent or Persistent Low-Grade Serous Carcinomas of the Ovary, Fallopian Tube, or Primary Peritoneum.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology

BJ Monk, RN Grisham, S Banerjee, E Kalbacher, MR Mirza, I Romero, P Vuylsteke, RL Coleman, F Hilpert, AM Oza, A Westermann, MK Oehler, S Pignata, C Aghajanian, N Colombo, E Drill, D Cibula, KN Moore, J Christy-Bittel, JM Del Campo, R Berger, C Marth, J Sehouli, DM O'Malley, C Churruca, AP Boyd, G Kristensen, A Clamp, I Ray-Coquard, I Vergote

Publication Date: 2020-11-10

Variant appearance in text: N/A

PubMed Link: 32822286

Variant Present in the following documents:

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Melanoma brain metastases: review of histopathological features and immune-molecular aspects.

Melanoma Management

L Salvati, M Mandalà, D Massi

Publication Date: 2020-06-08

Variant appearance in text: N/A

PubMed Link: 32821376

Variant Present in the following documents:

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Risk factors for MEK-associated retinopathy in patients with advanced melanoma treated with combination BRAF and MEK inhibitor therapy.

Therapeutic Advances In Medical Oncology

AEC Booth, AM Hopkins, A Rowland, G Kichenadasse, JR Smith, MJ Sorich

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32821295

Variant Present in the following documents:

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Targeting Mutant KRAS in Pancreatic Cancer: Futile or Promising?

Biomedicines

FI Nollmann, DA Ruess

Publication Date: 2020-08-11

Variant appearance in text: N/A

PubMed Link: 32796566

Variant Present in the following documents:

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BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation.

Oncogene

N Reischmann, G Andrieux, R Griffin, T Reinheckel, M Boerries, T Brummer

Publication Date: 2020-09

Variant appearance in text: N/A

PubMed Link: 32792685

Variant Present in the following documents:

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TERT Promoter Mutation as an Independent Prognostic Marker for Poor Prognosis MAPK Inhibitors-Treated Melanoma.

Cancers

P Blateau, E Coyaud, E Laurent, B Béganton, V Ducros, G Chauchard, JA Vendrell, J Solassol

Publication Date: 2020-08-09

Variant appearance in text: N/A

PubMed Link: 32784823

Variant Present in the following documents:

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Photochemical and Photobiological Properties of Pyridyl-pyrazol(in)e-Based Ruthenium(II) Complexes with Sub-micromolar Cytotoxicity for Phototherapy.

Acs Omega

D Havrylyuk, DK Heidary, Y Sun, S Parkin, EC Glazer

Publication Date: 2020-08-04

Variant appearance in text: N/A

PubMed Link: 32775891

Variant Present in the following documents:

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Mutations in the BRAF, NRAS, and C-KIT Genes of Patients Diagnosed with Melanoma in Colombia Population.

Biomed Research International

LD Gutiérrez-Castañeda, M Gamboa, JA Nova, L Pulido, JD Tovar-Parra

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32775409

Variant Present in the following documents:

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Primary Melanoma of the Lung Treated with Surgery, Dabrafenib and Trametinib.

Case Reports In Oncology

LG Landgraf, MA Malias, SJ Patterson

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32774277

Variant Present in the following documents:

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Current State of Target Treatment in BRAF Mutated Melanoma.

Frontiers In Molecular Biosciences

ET Tanda, I Vanni, A Boutros, V Andreotti, W Bruno, P Ghiorzo, F Spagnolo

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32760738

Variant Present in the following documents:

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Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients.

Journal Of Clinical Medicine

M Colombino, C Rozzo, P Paliogiannis, M Casula, A Manca, V Doneddu, MA Fedeli, MC Sini, G Palomba, M Pisano, PA Ascierto, C Caracò, A Lissia, A Cossu, G Palmieri

Publication Date: 2020-07-30

Variant appearance in text: N/A

PubMed Link: 32751423

Variant Present in the following documents:

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Personalized Treatment Selection and Disease Monitoring Using Circulating Tumor DNA Profiling in Real-World Cancer Patient Management.

Diagnostics (Basel, Switzerland)

J Wehrle, U Philipp, M Jolic, M Follo, S Hussung, S Waldeck, M Deuter, M Rassner, J Braune, J Rawluk, C Greil, CF Waller, H Becker, J Duque-Afonso, AL Illert, RM Fritsch, F Meiss, J Duyster, N von Bubnoff, F Scherer

Publication Date: 2020-08-02

Variant appearance in text: N/A

PubMed Link: 32748806

Variant Present in the following documents:

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Plasmacytoid Dendritic Cell Impairment in Metastatic Melanoma by Lactic Acidosis.

Cancers

M Monti, R Vescovi, F Consoli, D Farina, D Moratto, A Berruti, C Specchia, W Vermi

Publication Date: 2020-07-28

Variant appearance in text: N/A

PubMed Link: 32731406

Variant Present in the following documents:

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Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response.

Cancers

MK van der Kooij, MJAL Wetzels, MJB Aarts, FWPJ van den Berkmortel, CU Blank, MJ Boers-Sonderen, MP Dierselhuis, JWB de Groot, GAP Hospers, D Piersma, RS van Rijn, KPM Suijkerbuijk, AJ Ten Tije, AAM van der Veldt, G Vreugdenhil, MWJM Wouters, JBAG Haanen, AJM van den Eertwegh, E Bastiaannet, E Kapiteijn

Publication Date: 2020-07-27

Variant appearance in text: N/A

PubMed Link: 32726988

Variant Present in the following documents:

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Genetic Biomarkers in Melanoma of the Ocular Region: What the Medical Oncologist Should Know.

International Journal Of Molecular Sciences

KF Bol, M Donia, S Heegaard, JF Kiilgaard, IM Svane

Publication Date: 2020-07-23

Variant appearance in text: N/A

PubMed Link: 32718045

Variant Present in the following documents:

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Ultraviolet Radiation and Melanomagenesis: From Mechanism to Immunotherapy.

Frontiers In Oncology

X Sun, N Zhang, C Yin, B Zhu, X Li

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32714859

Variant Present in the following documents:

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The Roles of Common Variation and Somatic Mutation in Cancer Pharmacogenomics.

Oncology And Therapy

HT Chan, YM Chin, SK Low

Publication Date: 2019-06

Variant appearance in text: N/A

PubMed Link: 32700193

Variant Present in the following documents:

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The Current State of Molecular Testing in the BRAF-Mutated Melanoma Landscape.

Frontiers In Molecular Biosciences

I Vanni, ET Tanda, F Spagnolo, V Andreotti, W Bruno, P Ghiorzo

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32695793

Variant Present in the following documents:

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Spontaneous Regression of Primary Melanoma and Multiple Melanocytic Nevi in a Patient With Metastatic Melanoma.

Dermatology Practical & Conceptual

G Paolino, N Rizzo, R Pampena, P Bearzi, A Bulotta, V Gregorc, P Brianti, E Moliterni, SR Mercuri

Publication Date: 2020-07

Variant appearance in text: N/A

PubMed Link: 32685272

Variant Present in the following documents:

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Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions.

Journal Of Immunology Research

M Ralli, A Botticelli, IC Visconti, D Angeletti, M Fiore, P Marchetti, A Lambiase, M de Vincentiis, A Greco

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32671117

Variant Present in the following documents:

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Current and Future Role of Tyrosine Kinases Inhibition in Thyroid Cancer: From Biology to Therapy.

International Journal Of Molecular Sciences

M San Román Gil, J Pozas, J Molina-Cerrillo, J Gómez, H Pian, M Pozas, A Carrato, E Grande, T Alonso-Gordoa

Publication Date: 2020-07-13

Variant appearance in text: N/A

PubMed Link: 32668761

Variant Present in the following documents:

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Circulating Tumour DNA Is an Independent Prognostic Biomarker for Survival in Metastatic BRAF or NRAS-Mutated Melanoma Patients.

Cancers

G Herbreteau, A Vallée, AC Knol, S Théoleyre, G Quéreux, C Frénard, E Varey, P Hofman, A Khammari, B Dréno, MG Denis

Publication Date: 2020-07-11

Variant appearance in text: N/A

PubMed Link: 32664549

Variant Present in the following documents:

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Toxicity of combined targeted therapy and concurrent radiotherapy in metastatic melanoma patients: a single-center retrospective analysis.

Melanoma Research

JS Ziegler, S Kroeze, ML Hilbers, L Imhof, M Guckenberger, MP Levesque, R Dummer, P Cheng, J Mangana

Publication Date: 2020-12

Variant appearance in text: N/A

PubMed Link: 32658050

Variant Present in the following documents:

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Clinical Relevance of BRAF V600E Mutation Status in Brain Tumors with a Focus on a Novel Management Algorithm.

Targeted Oncology

A Kowalewski, J Durślewicz, M Zdrenka, D Grzanka, Ł Szylberg

Publication Date: 2020-08

Variant appearance in text: N/A

PubMed Link: 32648041

Variant Present in the following documents:

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BRAF Inhibitors: Molecular Targeting and Immunomodulatory Actions.

Cancers

I Proietti, N Skroza, S Michelini, A Mambrin, V Balduzzi, N Bernardini, A Marchesiello, E Tolino, S Volpe, P Maddalena, M Di Fraia, G Mangino, G Romeo, C Potenza

Publication Date: 2020-07-07

Variant appearance in text: N/A

PubMed Link: 32645969

Variant Present in the following documents:

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Characterization of Class-3 Semaphorin Receptors, Neuropilins and Plexins, as Therapeutic Targets in a Pan-Cancer Study.

Cancers

X Zhang, S Shao, L Li

Publication Date: 2020-07-06

Variant appearance in text: N/A

PubMed Link: 32640719

Variant Present in the following documents:

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The Potential of Tumor Debulking to Support Molecular Targeted Therapies.

Frontiers In Oncology

F Oppel, M Görner, H Sudhoff

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32626653

Variant Present in the following documents:

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Optimal treatment strategy for metastatic melanoma patients harboring BRAF-V600 mutations.

Therapeutic Advances In Medical Oncology

EF Giunta, V De Falco, S Napolitano, G Argenziano, G Brancaccio, E Moscarella, D Ciardiello, F Ciardiello, T Troiani

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32612709

Variant Present in the following documents:

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Cytotoxic Effect of Vanicosides A and B from Reynoutria sachalinensis Against Melanotic and Amelanotic Melanoma Cell Lines and in silico Evaluation for Inhibition of BRAFV600E and MEK1.

International Journal Of Molecular Sciences

I Nawrot-Hadzik, A Choromańska, R Abel, R Preissner, J Saczko, A Matkowski, J Hadzik

Publication Date: 2020-06-29

Variant appearance in text: N/A

PubMed Link: 32610527

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Targeted Therapy in Melanoma and Mechanisms of Resistance.

International Journal Of Molecular Sciences

AM Czarnecka, E Bartnik, M Fiedorowicz, P Rutkowski

Publication Date: 2020-06-27

Variant appearance in text: N/A

PubMed Link: 32605090

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KRAS and BRAF Concomitant Mutations in a Patient with Metastatic Colon Adenocarcinoma: An Interesting Case Report.

Case Reports In Oncology

C Cafiero, A Re, G D'Amato, PL Surico, G Surico, M Pirrelli, S Pisconti

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32595468

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Circulating Tumor DNA Correlates with Outcome in Metastatic Melanoma Treated by BRAF and MEK Inhibitors - Results of a Prospective Biomarker Study.

Oncotargets And Therapy

A Forschner, S Weißgraeber, D Hadaschik, M Schulze, M Kopp, S Kelkenberg, T Sinnberg, C Garbe, S Biskup, F Battke

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32581559

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Calcium-sensing receptor autoantibody-mediated hypoparathyroidism associated with immune checkpoint inhibitor therapy: diagnosis and long-term follow-up.

Journal For Immunotherapy Of Cancer

R Dadu, TE Rodgers, VA Trinh, EH Kemp, TD Cubb, S Patel, JM Simon, EM Burton, H Tawbi

Publication Date: 2020-06

Variant appearance in text: N/A

PubMed Link: 32581059

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Melanoma Brain Metastases in the Era of Target Therapies: An Overview.

Cancers

P Becco, S Gallo, S Poletto, MPM Frascione, L Crotto, A Zaccagna, L Paruzzo, D Caravelli, F Carnevale-Schianca, M Aglietta

Publication Date: 2020-06-21

Variant appearance in text: N/A

PubMed Link: 32575838

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The Evolution of Care of Cancers of the Head and Neck Region: State of the Science in 2020.

Cancers

F Yan, HM Knochelmann, PF Morgan, JM Kaczmar, DM Neskey, EM Graboyes, SA Nguyen, B Ogretmen, AK Sharma, TA Day

Publication Date: 2020-06-11

Variant appearance in text: N/A

PubMed Link: 32545409

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Integration of Digital Pathologic and Transcriptomic Analyses Connects Tumor-Infiltrating Lymphocyte Spatial Density With Clinical Response to BRAF Inhibitors.

Frontiers In Oncology

A Ziemys, M Kim, AM Menzies, JS Wilmott, GV Long, RA Scolyer, L Kwong, A Holder, G Boland

Publication Date: 2020

Variant appearance in text: N/A

PubMed Link: 32528881

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000288602.6	c.1798G>C	p.Val600Leu	missense_variant	15/18	-
ENST00000479537.1	c.82G>C	p.Val28Leu	missense_variant,NMD_transcript_variant	2/6	-
ENST00000496384.2	c.622G>C	p.Val208Leu	missense_variant	6/10	-
ENST00000497784.1	c.*1248G>C	-	3_prime_UTR_variant,NMD_transcript_variant	16/19	-
NM_001354609.2	c.1798G>C	p.Val600Leu	missense_variant	15/19	-
NM_004333.6	c.1798G>C	p.Val600Leu	missense_variant	15/18	-
NR_148928.2	n.2897G>C	-	non_coding_transcript_exon_variant	15/18	-