Publications:

Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation.

Journal Of Medicinal Chemistry

Beneker, Chad M CM; Rovoli, Magdalini M; Kontopidis, George G; Röring, Michael M; Galda, Simeon S; Braun, Sandra S; Brummer, Tilman T; McInnes, Campbell C

Publication Date: 2019-04-25

Variant appearance in text: BRAF: L514A

PubMed Link: 30977659

Variant Present in the following documents:

• Main text

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Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.

Acs Chemical Biology

Xie, Peng P; Williams, Douglas S DS; Atilla-Gokcumen, G Ekin GE; Milk, Leslie L; Xiao, Min M; Smalley, Keiran S M KS; Herlyn, Meenhard M; Meggers, Eric E; Marmorstein, Ronen R

Publication Date: 2008-05-16

Variant appearance in text: BRAF: L514A

PubMed Link: 18484710

Variant Present in the following documents:

• Main text

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