BRAF c.1418A>G ;(p.K473R)

Variant ID: 7-140481390-T-C

NM_004333.4(BRAF):c.1418A>G;(p.K473R)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Acetylation-dependent regulation of BRAF oncogenic function.

Cell Reports
Dai, Xiangpeng X; Zhang, Xiaoling X; Yin, Qing Q; Hu, Jia J; Guo, Jianping J; Gao, Yang Y; Snell, Aidan H AH; Inuzuka, Hiroyuki H; Wan, Lixin L; Wei, Wenyi W
Publication Date: 2022-01-18

Variant appearance in text: BRAF: K473R
PubMed Link: 35045286
Variant Present in the following documents:
  • Main text
  • nihms-1772773.pdf
View BVdb publication page



Acetylation-dependent regulation of BRAF oncogenic function.

Cell Reports
Dai, Xiangpeng X; Zhang, Xiaoling X; Yin, Qing Q; Hu, Jia J; Guo, Jianping J; Gao, Yang Y; Snell, Aidan H AH; Inuzuka, Hiroyuki H; Wan, Lixin L; Wei, Wenyi W
Publication Date: 2022-01-18

Variant appearance in text: BRAF: K473R
PubMed Link: 35045286
Variant Present in the following documents:
  • Main text
  • nihms-1772773.pdf
View BVdb publication page



K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling.

Nature Communications
Yin, Qing Q; Han, Tao T; Fang, Bin B; Zhang, Guolin G; Zhang, Chao C; Roberts, Evan R ER; Izumi, Victoria V; Zheng, Mengmeng M; Jiang, Shulong S; Yin, Xiu X; Kim, Minjung M; Cai, Jianfeng J; Haura, Eric B EB; Koomen, John M JM; Smalley, Keiran S M KSM; Wan, Lixin L
Publication Date: 2019-04-23

Variant appearance in text: BRAF: K473R
PubMed Link: 31015455
Variant Present in the following documents:
  • Main text
  • 41467_2019_9844_MOESM1_ESM.pdf
  • 41467_2019_Article_9844.pdf
View BVdb publication page



Resectable lung lesions malignancy assessment and cancer detection by ultra-deep sequencing of targeted gene mutations in plasma cell-free DNA.

Journal Of Medical Genetics
Peng, Muyun M; Xie, Yuancai Y; Li, Xiaohua X; Qian, Youhui Y; Tu, Xiaonian X; Yao, Xumei X; Cheng, Fangsheng F; Xu, Feiyue F; Kong, Deju D; He, Bing B; Liu, Chaoyu C; Cao, Fengjun F; Yang, Haoxian H; Yu, Fenglei F; Xu, Chuanbo C; Tian, Geng G
Publication Date: 2019-10

Variant appearance in text: BRAF: 1418A>G; Lys473Arg
PubMed Link: 30981987
Variant Present in the following documents:
  • jmedgenet-2018-105825supp002.xlsx, sheet 5
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: BRAF: 1418A>G
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page