BRAF c.1393T>G ;(p.S465A)

Variant ID: 7-140481415-A-C

NM_004333.4(BRAF):c.1393T>G;(p.S465A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling.

The Journal Of Biological Chemistry
Cope, Nicholas J NJ; Novak, Borna B; Liu, Zhiwei Z; Cavallo, Maria M; Gunderwala, Amber Y AY; Connolly, Matthew M; Wang, Zhihong Z
Publication Date: 2020-02-21

Variant appearance in text: BRAF: S465A
PubMed Link: 31929109
Variant Present in the following documents:
  • Main text
View BVdb publication page



Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.

Nature Communications
Chen, Ming M; Wan, Lixin L; Zhang, Jiangwen J; Zhang, Jinfang J; Mendez, Lourdes L; Clohessy, John G JG; Berry, Kelsey K; Victor, Joshua J; Yin, Qing Q; Zhu, Yuan Y; Wei, Wenyi W; Pandolfi, Pier Paolo PP
Publication Date: 2018-01-15

Variant appearance in text: BRAF: S465A
PubMed Link: 29335436
Variant Present in the following documents:
  • 41467_2017_Article_2272.pdf
View BVdb publication page



Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.

Oncotarget
Eisenhardt, Anja E AE; Sprenger, Adrian A; Röring, Michael M; Herr, Ricarda R; Weinberg, Florian F; Köhler, Martin M; Braun, Sandra S; Orth, Joachim J; Diedrich, Britta B; Lanner, Ulrike U; Tscherwinski, Natalja N; Schuster, Simon S; Dumaz, Nicolas N; Schmidt, Enrico E; Baumeister, Ralf R; Schlosser, Andreas A; Dengjel, Jörn J; Brummer, Tilman T
Publication Date: 2016-05-03

Variant appearance in text: BRAF: S465A
PubMed Link: 27034005
Variant Present in the following documents:
  • Main text
View BVdb publication page