BRAF c.1391G>A ;(p.G464E)

Variant ID: 7-140481417-C-T

NM_004333.4(BRAF):c.1391G>A;(p.G464E)

This variant was identified in 108 publications

View GRCh38 version.




Publications:


An integrated model for predicting KRAS dependency.

Plos Computational Biology
Tsai, Yihsuan S YS; Chareddy, Yogitha S YS; Price, Brandon A BA; Parker, Joel S JS; Pecot, Chad V CV
Publication Date: 2023-05-04

Variant appearance in text: BRAF: G464E
PubMed Link: 37141389
Variant Present in the following documents:
  • Main text
  • pcbi.1011095.pdf
View BVdb publication page



Pathogenic genomic alterations in Chinese pancreatic cancer patients and their therapeutical implications.

Cancer Medicine
Zhao, Zhiming Z; Li, Xiaomo X; Wang, Fei F; Xu, Yong Y; Liu, Si S; Han, Quanli Q; Yang, Zhiying Z; Huang, Weiwei W; Yin, Zhuzeng Z; Liu, Qu Q; Tan, Haidong H; Ma, Tonghui T; Si, Shuang S; Huang, Jia J; Yuan, Hongling H; Li, Wei W; Liu, Rong R
Publication Date: 2023-03-31

Variant appearance in text: BRAF: G464E
PubMed Link: 36999792
Variant Present in the following documents:
  • CAM4-12-11672.pdf
View BVdb publication page



Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
Publication Date: 2022-09

Variant appearance in text: rs121913348
PubMed Link: 36922933
Variant Present in the following documents:
  • crc-22-0136-s01.xlsx, sheet 1
View BVdb publication page



Precision Medicine Approach Based on Molecular Alterations for Patients with Relapsed or Refractory Multiple Myeloma: Results from the MM-EP1 Study.

Cancers
Andreozzi, Fabio F; Dragani, Matteo M; Quivoron, Cyril C; Le Bras, Fabien F; Assi, Tarek T; Danu, Alina A; Belhadj, Karim K; Lazarovici, Julien J; Cotteret, Sophie S; Bernard, Olivier A OA; Ribrag, Vincent V; Michot, Jean-Marie JM
Publication Date: 2023-02-28

Variant appearance in text: BRAF: G464E
PubMed Link: 36900299
Variant Present in the following documents:
  • cancers-15-01508.pdf
View BVdb publication page



Association of BRAF Variants With Disease Characteristics, Prognosis, and Targeted Therapy Response in Intrahepatic Cholangiocarcinoma.

Jama Network Open
Xin, Hao-Yang HY; Sun, Rong-Qi RQ; Zou, Ji-Xue JX; Wang, Peng-Cheng PC; Wang, Jia-Yin JY; Ye, Yu-Hang YH; Liu, Kai-Xuan KX; Hu, Zhi-Qiang ZQ; Zhou, Zheng-Jun ZJ; Fan, Jia J; Zhou, Jian J; Zhou, Shao-Lai SL
Publication Date: 2023-03-01

Variant appearance in text: BRAF: G464E
PubMed Link: 36867406
Variant Present in the following documents:
  • jamanetwopen-e231476-s001.pdf
View BVdb publication page



Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery
Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI
Publication Date: 2023-03-02

Variant appearance in text: BRAF: G464E
PubMed Link: 36862804
Variant Present in the following documents:
  • cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 5
View BVdb publication page



Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica
Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z
Publication Date: 2022-12-30

Variant appearance in text: BRAF: G464E
PubMed Link: 36799315
Variant Present in the following documents:
  • AMA-51-217.pdf
View BVdb publication page



Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer.

Molecular Biomedicine
Wang, Zixi Z; Xing, Yurou Y; Li, Bingjie B; Li, Xiaoyu X; Liu, Bin B; Wang, Yongsheng Y
Publication Date: 2022-12-12

Variant appearance in text: BRAF: G464E
PubMed Link: 36508072
Variant Present in the following documents:
  • Main text
  • 43556_2022_Article_107.pdf
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: BRAF: G464E
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Integrated gene analyses of de novo variants from 46,612 trios with autism and developmental disorders.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Wang, Tianyun T; Kim, Chang N CN; Bakken, Trygve E TE; Gillentine, Madelyn A MA; Henning, Barbara B; Mao, Yafei Y; Gilissen, Christian C; , ; Nowakowski, Tomasz J TJ; Eichler, Evan E EE
Publication Date: 2022-11-15

Variant appearance in text: BRAF: 1391G>A; Gly464Glu
PubMed Link: 36350923
Variant Present in the following documents:
  • pnas.2203491119.sd01.xlsx, sheet 1
View BVdb publication page



The Genetic Architecture of Vascular Anomalies: Current Data and Future Therapeutic Perspectives Correlated with Molecular Mechanisms.

International Journal Of Molecular Sciences
Butnariu, Lăcrămioara Ionela LI; Gorduza, Eusebiu Vlad EV; Florea, Laura L; Țarcă, Elena E; Moisă, Ștefana Maria ȘM; Trandafir, Laura Mihaela LM; Stoleriu, Simona S; Bădescu, Minerva Codruța MC; Luca, Alina-Costina AC; Popa, Setalia S; Radu, Iulian I; Cojocaru, Elena E
Publication Date: 2022-10-13

Variant appearance in text: BRAF: 1391G>A; Gly464Glu
PubMed Link: 36293054
Variant Present in the following documents:
  • Main text
  • ijms-23-12199.pdf
View BVdb publication page



Clinical associations and genetic interactions of oncogenic BRAF alleles.

Peerj
Wagner, Sebastian A SA
Publication Date: 2022

Variant appearance in text: BRAF: G464E
PubMed Link: 36275468
Variant Present in the following documents:
  • peerj-10-14126.pdf
View BVdb publication page



Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.

The Journal Of Pathology
Birkeälv, Sofia S; Harland, Mark M; Matsuyama, Larissa Satiko Alcantara Sekimoto LSAS; Rashid, Mamun M; Mehta, Ishan I; Laye, Jonathan P JP; Haase, Kerstin K; Mell, Tracey T; Iyer, Vivek V; Robles-Espinoza, Carla Daniela CD; McDermott, Ultan U; van Loo, Peter P; Kuijjer, Marieke L ML; Possik, Patricia A PA; Maria Engler, Silvya Stuchi SS; Bishop, D Timothy DT; Newton-Bishop, Julia J; Adams, David J DJ
Publication Date: 2022-10-11

Variant appearance in text: BRAF: G464E
PubMed Link: 36219477
Variant Present in the following documents:
  • PATH-259-56-s006.xlsx, sheet 2
  • PATH-259-56-s004.xlsx, sheet 2
View BVdb publication page



BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors.

Cancers
Talloa, Dario D; Triarico, Silvia S; Agresti, Pierpaolo P; Mastrangelo, Stefano S; Attinà, Giorgio G; Romano, Alberto A; Maurizi, Palma P; Ruggiero, Antonio A
Publication Date: 2022-08-31

Variant appearance in text: BRAF: G464E
PubMed Link: 36077798
Variant Present in the following documents:
  • Main text
  • cancers-14-04264.pdf
View BVdb publication page



Integrating de novo and inherited variants in 42,607 autism cases identifies mutations in new moderate-risk genes.

Nature Genetics
Zhou, Xueya X; Feliciano, Pamela P; Shu, Chang C; Wang, Tianyun T; Astrovskaya, Irina I; Hall, Jacob B JB; Obiajulu, Joseph U JU; Wright, Jessica R JR; Murali, Shwetha C SC; Xu, Simon Xuming SX; Brueggeman, Leo L; Thomas, Taylor R TR; Marchenko, Olena O; Fleisch, Christopher C; Barns, Sarah D SD; Snyder, LeeAnne Green LG; Han, Bing B; Chang, Timothy S TS; Turner, Tychele N TN; Harvey, William T WT; Nishida, Andrew A; O'Roak, Brian J BJ; Geschwind, Daniel H DH; , ; Michaelson, Jacob J JJ; Volfovsky, Natalia N; Eichler, Evan E EE; Shen, Yufeng Y; Chung, Wendy K WK
Publication Date: 2022-09

Variant appearance in text: BRAF: 1391G>A; G464E
PubMed Link: 35982159
Variant Present in the following documents:
  • 41588_2022_1148_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: BRAF: 1391G>A; G464E
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: BRAF: G464E
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis.

Cell Death & Disease
Kim, Hyunjoo H; Jeong, Muhah M; Na, Do-Hyeong DH; Ryu, Shin-Hyeon SH; Jeong, Eun Il EI; Jung, Kwangmin K; Kang, Jaemin J; Lee, Ho-June HJ; Sim, Taebo T; Yu, Dae-Yeul DY; Yu, Hee Chul HC; Cho, Baik-Hwan BH; Jung, Yong-Keun YK
Publication Date: 2022-05-18

Variant appearance in text: BRAF: G464E
PubMed Link: 35585049
Variant Present in the following documents:
  • Main text
  • 41419_2022_Article_4921.pdf
View BVdb publication page



Large-scale discovery of novel neurodevelopmental disorder-related genes through a unified analysis of single-nucleotide and copy number variants.

Genome Medicine
Hamanaka, Kohei K; Miyake, Noriko N; Mizuguchi, Takeshi T; Miyatake, Satoko S; Uchiyama, Yuri Y; Tsuchida, Naomi N; Sekiguchi, Futoshi F; Mitsuhashi, Satomi S; Tsurusaki, Yoshinori Y; Nakashima, Mitsuko M; Saitsu, Hirotomo H; Yamada, Kohei K; Sakamoto, Masamune M; Fukuda, Hiromi H; Ohori, Sachiko S; Saida, Ken K; Itai, Toshiyuki T; Azuma, Yoshiteru Y; Koshimizu, Eriko E; Fujita, Atsushi A; Erturk, Biray B; Hiraki, Yoko Y; Ch'ng, Gaik-Siew GS; Kato, Mitsuhiro M; Okamoto, Nobuhiko N; Takata, Atsushi A; Matsumoto, Naomichi N
Publication Date: 2022-04-26

Variant appearance in text: BRAF: 1391G>A; Gly464Glu
PubMed Link: 35468861
Variant Present in the following documents:
  • 13073_2022_1042_MOESM2_ESM.xls, sheet 8
View BVdb publication page



KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.

Cancers
Vendramini, Elena E; Bomben, Riccardo R; Pozzo, Federico F; Bittolo, Tamara T; Tissino, Erika E; Gattei, Valter V; Zucchetto, Antonella A
Publication Date: 2022-01-28

Variant appearance in text: BRAF: G464E
PubMed Link: 35158933
Variant Present in the following documents:
  • Main text
  • cancers-14-00666.pdf
View BVdb publication page



KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.

Cancers
Vendramini, Elena E; Bomben, Riccardo R; Pozzo, Federico F; Bittolo, Tamara T; Tissino, Erika E; Gattei, Valter V; Zucchetto, Antonella A
Publication Date: 2022-01-28

Variant appearance in text: BRAF: G464E
PubMed Link: 35158933
Variant Present in the following documents:
  • Main text
  • cancers-14-00666.pdf
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913348
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 6
View BVdb publication page



KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas.

Plos One
Rudd, Meghan L ML; Hansen, Nancy F NF; Zhang, Xiaolu X; Urick, Mary Ellen ME; Zhang, Suiyuan S; Merino, Maria J MJ; , ; Mullikin, James C JC; Brody, Lawrence C LC; Bell, Daphne W DW
Publication Date: 2022

Variant appearance in text: rs121913348
PubMed Link: 35081118
Variant Present in the following documents:
  • pone.0251286.s005.xlsx, sheet 6
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: BRAF: G464E
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Definition of Biologically Distinct Groups of Conjunctival Melanomas According to Etiological Factors and Implications for Precision Medicine.

Cancers
Gardrat, Sophie S; Houy, Alexandre A; Brooks, Kelly K; Cassoux, Nathalie N; Barnhill, Raymond R; Dayot, Stéphane S; Bièche, Ivan I; Raynal, Virginie V; Baulande, Sylvain S; Marais, Richard R; Roman-Roman, Sergio S; Stern, Marc-Henri MH; Rodrigues, Manuel M
Publication Date: 2021-07-30

Variant appearance in text: BRAF: G464E
PubMed Link: 34359736
Variant Present in the following documents:
  • Main text
  • cancers-13-03836.pdf
View BVdb publication page



Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology
Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN
Publication Date: 2021

Variant appearance in text: BRAF: G464E
PubMed Link: 34113354
Variant Present in the following documents:
  • Table_1.xlsx, sheet 31
View BVdb publication page



Prognostic Value of ctDNA Mutation in Melanoma: A Meta-Analysis.

Journal Of Oncology
Zheng, Yang Y; Sun, Hongyan H; Cong, Lele L; Liu, Chenlu C; Sun, Qian Q; Wu, Nan N; Cong, Xianling X
Publication Date: 2021

Variant appearance in text: BRAF: G464E
PubMed Link: 34035810
Variant Present in the following documents:
  • Main text
  • JO2021-6660571.pdf
View BVdb publication page



RTK Inhibitors in Melanoma: From Bench to Bedside.

Cancers
Sabbah, Malak M; Najem, Ahmad A; Krayem, Mohammad M; Awada, Ahmad A; Journe, Fabrice F; Ghanem, Ghanem E GE
Publication Date: 2021-04-02

Variant appearance in text: BRAF: G464E
PubMed Link: 33918490
Variant Present in the following documents:
  • Main text
View BVdb publication page



Novel and Potent Small Molecules against Melanoma Harboring BRAF Class I/II/III Mutants for Overcoming Drug Resistance.

International Journal Of Molecular Sciences
Kim, Namkyoung N; Shin, Injae I; Lee, Jiwon J; Jeon, Eunhye E; Kim, Younghoon Y; Ryu, Seongshick S; Ju, Eunhye E; Cho, Wonjeong W; Sim, Taebo T
Publication Date: 2021-04-06

Variant appearance in text: BRAF: G464E
PubMed Link: 33917428
Variant Present in the following documents:
  • Main text
View BVdb publication page



Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications
Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L
Publication Date: 2021-04-19

Variant appearance in text: BRAF: G464E
PubMed Link: 33875650
Variant Present in the following documents:
  • 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
  • 41467_2021_22481_MOESM4_ESM.xlsx, sheet 5
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: BRAF: 1391G>A; G464E
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Molecular profile of KRAS G12C-mutant colorectal and non-small-cell lung cancer.

Bmc Cancer
Araujo, Luiz Henrique LH; Souza, Bianca Mendes BM; Leite, Laura Rabelo LR; Parma, Sabrina A F SAF; Lopes, Natália P NP; Malta, Frederico S V FSV; Freire, Maíra C M MCM
Publication Date: 2021-02-25

Variant appearance in text: BRAF: G464E
PubMed Link: 33632153
Variant Present in the following documents:
  • Main text
View BVdb publication page



Discovery of a new molecule inducing melanoma cell death: dual AMPK/MELK targeting for novel melanoma therapies.

Cell Death & Disease
Jaune, Emilie E; Cavazza, Elisa E; Ronco, Cyril C; Grytsai, Oleksandr O; Abbe, Patricia P; Tekaya, Nedra N; Zerhouni, Marwa M; Beranger, Guillaume G; Kaminski, Lisa L; Bost, Frédéric F; Gesson, Maeva M; Tulic, Meri M; Hofman, Paul P; Ballotti, Robert R; Passeron, Thierry T; Botton, Thomas T; Benhida, Rachid R; Rocchi, Stéphane S
Publication Date: 2021-01-11

Variant appearance in text: BRAF: G464E
PubMed Link: 33431809
Variant Present in the following documents:
  • 41419_2020_Article_3344.pdf
View BVdb publication page



Clinicopathologic Features and Prognosis of BRAF Mutated Colorectal Cancer Patients.

Frontiers In Oncology
Guan, Wen-Long WL; Qiu, Miao-Zhen MZ; He, Cai-Yun CY; Yang, Li-Qiong LQ; Jin, Ying Y; Wang, Zhi-Qiang ZQ; Li, Yu-Hong YH; Xu, Rui-Hua RH; Wang, Feng-Hua FH
Publication Date: 2020

Variant appearance in text: BRAF: G464E
PubMed Link: 33330032
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



BRAF: A Two-Faced Janus.

Cells
Pisapia, Pasquale P; Pepe, Francesco F; Iaccarino, Antonino A; Sgariglia, Roberta R; Nacchio, Mariantonia M; Russo, Gianluca G; Gragnano, Gianluca G; Malapelle, Umberto U; Troncone, Giancarlo G
Publication Date: 2020-11-27

Variant appearance in text: BRAF: G464E
PubMed Link: 33260892
Variant Present in the following documents:
  • Main text
  • cells-09-02549.pdf
View BVdb publication page



Genomic characterization of HIV-associated plasmablastic lymphoma identifies pervasive mutations in the JAK-STAT pathway.

Blood Cancer Discovery
Liu, Zhaoqi Z; Filip, Ioan I; Gomez, Karen K; Engelbrecht, Dewaldt D; Meer, Shabnum S; Lalloo, Pooja N PN; Patel, Pareen P; Perner, Yvonne Y; Zhao, Junfei J; Wang, Jiguang J; Pasqualucci, Laura L; Rabadan, Raul R; Willem, Pascale P
Publication Date: 2020-07

Variant appearance in text: BRAF: G464E
PubMed Link: 33225311
Variant Present in the following documents:
  • Main text
View BVdb publication page



Emerging BRAF Mutations in Cancer Progression and Their Possible Effects on Transcriptional Networks.

Genes
Śmiech, Magdalena M; Leszczyński, Paweł P; Kono, Hidetoshi H; Wardell, Christopher C; Taniguchi, Hiroaki H
Publication Date: 2020-11-12

Variant appearance in text: BRAF: G464E
PubMed Link: 33198372
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multicenter Comparison of Molecular Tumor Boards in The Netherlands: Definition, Composition, Methods, and Targeted Therapy Recommendations.

The Oncologist
Koopman, Bart B; Groen, Harry J M HJM; Ligtenberg, Marjolijn J L MJL; Grünberg, Katrien K; Monkhorst, Kim K; de Langen, Adrianus J AJ; Boelens, Mirjam C MC; Paats, Marthe S MS; von der Thüsen, Jan H JH; Dinjens, Winand N M WNM; Solleveld, Nienke N; van Wezel, Tom T; Gelderblom, Hans H; Hendriks, Lizza E LE; Speel, Ernst-Jan M EM; Theunissen, Tom E TE; Kroeze, Leonie I LI; Mehra, Niven N; Piet, Berber B; van der Wekken, Anthonie J AJ; Ter Elst, Arja A; Timens, Wim W; Willems, Stefan M SM; Meijers, Ruud W J RWJ; de Leng, Wendy W J WWJ; van Lindert, Anne S R ASR; Radonic, Teodora T; Hashemi, Sayed M S SMS; Heideman, Daniëlle A M DAM; Schuuring, Ed E; van Kempen, Léon C LC
Publication Date: 2021-08

Variant appearance in text: BRAF: G464E
PubMed Link: 33111480
Variant Present in the following documents:
  • Main text
  • ONCO-26-e1347.pdf
  • ONCO-26-e1347-s002.pdf
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs121913348
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: BRAF: G464E
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

Jco Precision Oncology
Sheikine, Yuri Y; Pavlick, Dean D; Klempner, Samuel J SJ; Trabucco, Sally E SE; Chung, Jon H JH; Rosenzweig, Mark M; Wang, Kai K; Velcheti, Vamsidhar V; Frampton, Garrett M GM; Peled, Nir N; Murray, Molly M; Chae, Young Kwang YK; Albacker, Lee A LA; Gay, Laurie L; Husain, Hatim H; Suh, James H JH; Millis, Sherri Z SZ; Reddy, Venkataprasanth P VP; Elvin, Julia A JA; Hartmaier, Ryan J RJ; Dowlati, Afshin A; Stephens, Phil P; Ross, Jeffrey S JS; Bivona, Trever G TG; Miller, Vincent A VA; Ganesan, Shridar S; Schrock, Alexa B AB; Ou, Sai-Hong Ignatius SI; Ali, Siraj M SM
Publication Date: 2018

Variant appearance in text: BRAF: G464E
PubMed Link: 32913992
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients.

Journal Of Clinical Medicine
Colombino, Maria M; Rozzo, Carla C; Paliogiannis, Panagiotis P; Casula, Milena M; Manca, Antonella A; Doneddu, Valentina V; Fedeli, Maria Antonietta MA; Sini, Maria Cristina MC; Palomba, Grazia G; Pisano, Marina M; Ascierto, Paolo A PA; Caracò, Corrado C; Lissia, Amelia A; Cossu, Antonio A; Palmieri, Giuseppe G
Publication Date: 2020-07-30

Variant appearance in text: BRAF: 1391G>A; G464E
PubMed Link: 32751423
Variant Present in the following documents:
  • Main text
  • jcm-09-02430.pdf
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A BRAF-Negative Classic Hairy Cell Leukemia Patient with Long-Lasting Complete Remission after Rituximab and Pentostatin

Turkish Journal Of Haematology : Official Journal Of Turkish Society Of Haematology
Gozzetti, Alessandro A; Sammartano, Vincenzo V; Bacchiarri, Francesca F; Raspadori, Donatella D; Bocchia, Monica M
Publication Date: 2020-11-19

Variant appearance in text: BRAF: G464E
PubMed Link: 32539314
Variant Present in the following documents:
  • Main text
  • TJH-37-286.pdf
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Landscape of drug-resistance mutations in kinase regulatory hotspots.

Briefings In Bioinformatics
Kim, Pora P; Li, Hanyang H; Wang, Junmei J; Zhao, Zhongming Z
Publication Date: 2021-05-20

Variant appearance in text: BRAF: G464E
PubMed Link: 32510566
Variant Present in the following documents:
  • Main text
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Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan.

Translational Oncology
Taniguchi, Hiroya H; Uehara, Keisuke K; Nakayama, Goro G; Nakayama, Hiroshi H; Aiba, Toshisada T; Hattori, Norifumi N; Kataoka, Masato M; Nakano, Yasuyuki Y; Kawase, Yoshihisa Y; Okochi, Osamu O; Matsuoka, Hiroshi H; Utsunomiya, Setsuo S; Sakamoto, Eiji E; Mori, Yoshinori Y; Umeda, Shinichi S; Shikano, Toshio T; Komori, Koji K; Tajika, Masahiro M; Kadowaki, Shigenori S; Muro, Kei K; Yatabe, Yasushi Y
Publication Date: 2020-07

Variant appearance in text: BRAF: G464E
PubMed Link: 32428838
Variant Present in the following documents:
  • Main text
  • main.pdf
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Cas9 activates the p53 pathway and selects for p53-inactivating mutations.

Nature Genetics
Enache, Oana M OM; Rendo, Veronica V; Abdusamad, Mai M; Lam, Daniel D; Davison, Desiree D; Pal, Sangita S; Currimjee, Naomi N; Hess, Julian J; Pantel, Sasha S; Nag, Anwesha A; Thorner, Aaron R AR; Doench, John G JG; Vazquez, Francisca F; Beroukhim, Rameen R; Golub, Todd R TR; Ben-David, Uri U
Publication Date: 2020-07

Variant appearance in text: BRAF: 1391G>A; G464E
PubMed Link: 32424350
Variant Present in the following documents:
  • NIHMS1581982-supplement-1581982_Supp_Dataset1-7.xlsx, sheet 7
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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: BRAF: G464E
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology
Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M
Publication Date: 2020-01-07

Variant appearance in text: BRAF: 1391G>A; G464E
PubMed Link: 31925297
Variant Present in the following documents:
  • 42003_2019_736_MOESM3_ESM.xlsx, sheet 1
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Trametinib Activity in Patients with Solid Tumors and Lymphomas Harboring BRAF Non-V600 Mutations or Fusions: Results from NCI-MATCH (EAY131).

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Johnson, Douglas B DB; Zhao, Fengmin F; Noel, Marcus M; Riely, Gregory J GJ; Mitchell, Edith P EP; Wright, John J JJ; Chen, Helen X HX; Gray, Robert J RJ; Li, Shuli S; McShane, Lisa M LM; Rubinstein, Larry V LV; Patton, David D; Williams, P Mickey PM; Hamilton, Stanly R SR; Conley, Barbara A BA; Arteaga, Carlos L CL; Harris, Lyndsay N LN; O'Dwyer, Peter J PJ; Chen, Alice P AP; Flaherty, Keith T KT
Publication Date: 2020-04-15

Variant appearance in text: BRAF: Gly464Glu
PubMed Link: 31924734
Variant Present in the following documents:
  • Main text
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Gene mutation profiling in Chinese colorectal cancer patients and its association with clinicopathological characteristics and prognosis.

Cancer Medicine
Ye, Zu-Lu ZL; Qiu, Miao-Zhen MZ; Tang, Tao T; Wang, Fang F; Zhou, Yi-Xin YX; Lei, Meng-Jie MJ; Guan, Wen-Long WL; He, Cai-Yun CY
Publication Date: 2020-01

Variant appearance in text: BRAF: G464E
PubMed Link: 31782259
Variant Present in the following documents:
  • Main text
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Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

Cell Death & Disease
Gagliardi, Mara M; Cotella, Diego D; Santoro, Claudio C; Corà, Davide D; Barlev, Nickolai A NA; Piacentini, Mauro M; Corazzari, Marco M
Publication Date: 2019-11-28

Variant appearance in text: BRAF: G464E
PubMed Link: 31780644
Variant Present in the following documents:
  • Main text
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Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers.

Nature Communications
Gopal, Priyanka P; Sarihan, Elif Irem EI; Chie, Eui Kyu EK; Kuzmishin, Gwendolyn G; Doken, Semihcan S; Pennell, Nathan A NA; Raymond, Daniel P DP; Murthy, Sudish C SC; Ahmad, Usman U; Raja, Siva S; Almeida, Francisco F; Sethi, Sonali S; Gildea, Thomas R TR; Peacock, Craig D CD; Adams, Drew J DJ; Abazeed, Mohamed E ME
Publication Date: 2019-11-13

Variant appearance in text: BRAF: G464E
PubMed Link: 31723142
Variant Present in the following documents:
  • 41467_2019_Article_13161.pdf
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Systematic analysis of the intersection of disease mutations with protein modifications.

Bmc Medical Genomics
Simpson, Claire M CM; Zhang, Bin B; Hornbeck, Peter V PV; Gnad, Florian F
Publication Date: 2019-07-25

Variant appearance in text: BRAF: G464E
PubMed Link: 31345222
Variant Present in the following documents:
  • 12920_2019_543_MOESM6_ESM.xlsx, sheet 3
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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: BRAF: G464E
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
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Computational algorithms for in silico profiling of activating mutations in cancer.

Cellular And Molecular Life Sciences : Cmls
Jordan, E Joseph EJ; Patil, Keshav K; Suresh, Krishna K; Park, Jin H JH; Mosse, Yael P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R
Publication Date: 2019-07

Variant appearance in text: BRAF: G464E
PubMed Link: 30982079
Variant Present in the following documents:
  • Main text
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