BRAF c.1375G>C ;(p.V459L)

Variant ID: 7-140481433-C-G

NM_004333.4(BRAF):c.1375G>C;(p.V459L)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery
Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI
Publication Date: 2023-03-02

Variant appearance in text: BRAF: V459L
PubMed Link: 36862804
Variant Present in the following documents:
  • cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 5
View BVdb publication page



Tumor-Type Agnostic, Targeted Therapies: BRAF Inhibitors Join the Group.

Acta Medica Academica
Vranic, Semir S; Basu, Gargi D GD; Hall, David W DW; Gatalica, Zoran Z
Publication Date: 2022-12-30

Variant appearance in text: BRAF: V459L
PubMed Link: 36799315
Variant Present in the following documents:
  • AMA-51-217.pdf
View BVdb publication page



BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors.

Cancers
Talloa, Dario D; Triarico, Silvia S; Agresti, Pierpaolo P; Mastrangelo, Stefano S; AttinĂ , Giorgio G; Romano, Alberto A; Maurizi, Palma P; Ruggiero, Antonio A
Publication Date: 2022-08-31

Variant appearance in text: BRAF: V459L
PubMed Link: 36077798
Variant Present in the following documents:
  • cancers-14-04264.pdf
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Association between BRAF mutant classification and the efficacy of pemetrexed-based chemotherapy in Chinese advanced non-small cell lung cancer patients: a multicenter retrospective study.

Translational Cancer Research
Lei, Lei L; Wang, Wen-Xian WX; Zhu, You-Cai YC; Pu, Xing-Xiang XX; Fang, Yong Y; Wang, Hong H; Zhuang, Wu W; Zhang, Yin-Bin YB; Wang, Li-Ping LP; Xu, Chun-Wei CW; Fang, Mei-Yu MY
Publication Date: 2020-10

Variant appearance in text: BRAF: V459L
PubMed Link: 35117215
Variant Present in the following documents:
  • Main text
  • tcr-09-10-6039.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: BRAF: V459L
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



BRAF: A Two-Faced Janus.

Cells
Pisapia, Pasquale P; Pepe, Francesco F; Iaccarino, Antonino A; Sgariglia, Roberta R; Nacchio, Mariantonia M; Russo, Gianluca G; Gragnano, Gianluca G; Malapelle, Umberto U; Troncone, Giancarlo G
Publication Date: 2020-11-27

Variant appearance in text: BRAF: V459L
PubMed Link: 33260892
Variant Present in the following documents:
  • Main text
  • cells-09-02549.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: BRAF: V459L
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Targeting Oncogenic BRAF: Past, Present, and Future.

Cancers
Zaman, Aubhishek A; Wu, Wei W; Bivona, Trever G TG
Publication Date: 2019-08-16

Variant appearance in text: BRAF: V459L
PubMed Link: 31426419
Variant Present in the following documents:
  • Main text
  • cancers-11-01197.pdf
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: BRAF: V459L
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.

Nature
Yao, Zhan Z; Yaeger, Rona R; Rodrik-Outmezguine, Vanessa S VS; Tao, Anthony A; Torres, Neilawattie M NM; Chang, Matthew T MT; Drosten, Matthias M; Zhao, Huiyong H; Cecchi, Fabiola F; Hembrough, Todd T; Michels, Judith J; Baumert, Hervé H; Miles, Linde L; Campbell, Naomi M NM; de Stanchina, Elisa E; Solit, David B DB; Barbacid, Mariano M; Taylor, Barry S BS; Rosen, Neal N
Publication Date: 2017-08-10

Variant appearance in text: BRAF: V459L
PubMed Link: 28783719
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations.

Molecular Systems Biology
Kiel, Christina C; Serrano, Luis L
Publication Date: 2014-05-06

Variant appearance in text: BRAF: V459L
PubMed Link: 24803665
Variant Present in the following documents:
  • MSB-10-5-727-s13.xls, sheet 1
View BVdb publication page



Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Bmc Genomics
Gnad, Florian F; Baucom, Albion A; Mukhyala, Kiran K; Manning, Gerard G; Zhang, Zemin Z
Publication Date: 2013

Variant appearance in text: BRAF: V459L
PubMed Link: 23819521
Variant Present in the following documents:
  • 1471-2164-14-S3-S7-S1.xlsx, sheet 1
View BVdb publication page



The energy landscape analysis of cancer mutations in protein kinases.

Plos One
Dixit, Anshuman A; Verkhivker, Gennady M GM
Publication Date: 2011

Variant appearance in text: BRAF: V459L
PubMed Link: 21998754
Variant Present in the following documents:
View BVdb publication page



Development and applications of a BRAF oligonucleotide microarray.

The Journal Of Molecular Diagnostics : Jmd
Kim, Il-Jin IJ; Kang, Hio Chung HC; Jang, Sang Geun SG; Ahn, Sun-A SA; Yoon, Hyun-Ju HJ; Park, Jae-Gahb JG
Publication Date: 2007-02

Variant appearance in text: BRAF: V459L
PubMed Link: 17251336
Variant Present in the following documents:
  • Main text
View BVdb publication page