Publications:

Rare case of triple mutant (KRAS + NRAS + BRAF) metastatic colon adenocarcinoma.

Bmj Case Reports

Vittal, Anusha A; Sharma, Disha D; Samanta, Ipsita I; Kasi, Anup A

Publication Date: 2019-09-12

Variant appearance in text: BRAF: S429Y

PubMed Link: 31519714

Variant Present in the following documents:

• Main text

View BVdb publication page

MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance.

Nature Communications

Sale, Matthew J MJ; Balmanno, Kathryn K; Saxena, Jayeta J; Ozono, Eiko E; Wojdyla, Katarzyna K; McIntyre, Rebecca E RE; Gilley, Rebecca R; Woroniuk, Anna A; Howarth, Karen D KD; Hughes, Gareth G; Dry, Jonathan R JR; Arends, Mark J MJ; Caro, Pilar P; Oxley, David D; Ashton, Susan S; Adams, David J DJ; Saez-Rodriguez, Julio J; Smith, Paul D PD; Cook, Simon J SJ

Publication Date: 2019-05-02

Variant appearance in text: BRAF: S429Y

PubMed Link: 31048689

Variant Present in the following documents:

• Main text
• 41467_2019_Article_9438.pdf

View BVdb publication page