BRAF c.976A>G ;(p.I326V)

Variant ID: 7-140500166-T-C

NM_004333.4(BRAF):c.976A>G;(p.I326V)

This variant was identified in 19 publications

View GRCh38 version.




Publications:


Clinicopathologic Characteristics of Grade 2/3 Meningiomas: A Perspective on the Role of Next-Generation Sequencing.

Frontiers In Oncology
Kim, Junhyung J; Hwang, Kihwan K; Kwon, Hyun Jung HJ; Lee, Ji Eun JE; Lee, Kyu Sang KS; Choe, Gheeyoung G; Han, Jung Ho JH; Kim, Chae-Yong CY
Publication Date: 2022

Variant appearance in text: BRAF: 976A>G; I326V; rs775040765
PubMed Link: 35774130
Variant Present in the following documents:
  • DataSheet_2.xlsx, sheet 2
View BVdb publication page



Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology
Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X
Publication Date: 2021

Variant appearance in text: BRAF: I326V; rs775040765
PubMed Link: 35186718
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Identification of Prognostic Biomarker Candidates Associated With Melanoma Using High-Dimensional Genomic Data.

Frontiers In Genetics
Kutt, Brody B; Burdorf, Rachel R; Bain, Travaughn T; Cameron, Nicardo N; Pearah, Alexia A; Subasi, Ersoy E; Carroll, David J DJ; Moore, Lisa K LK; Subasi, Munevver Mine MM
Publication Date: 2021

Variant appearance in text: BRAF: I326V
PubMed Link: 34589115
Variant Present in the following documents:
  • Main text
  • fgene-12-707105.pdf
View BVdb publication page



Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Communications Biology
Nagasawa, Satoi S; Kuze, Yuta Y; Maeda, Ichiro I; Kojima, Yasuyuki Y; Motoyoshi, Ai A; Onishi, Tatsuya T; Iwatani, Tsuguo T; Yokoe, Takamichi T; Koike, Junki J; Chosokabe, Motohiro M; Kubota, Manabu M; Seino, Hibiki H; Suzuki, Ayako A; Seki, Masahide M; Tsuchihara, Katsuya K; Inoue, Eisuke E; Tsugawa, Koichiro K; Ohta, Tomohiko T; Suzuki, Yutaka Y
Publication Date: 2021-04-01

Variant appearance in text: BRAF: I326V
PubMed Link: 33795819
Variant Present in the following documents:
  • 42003_2021_1959_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Unique Genomic Landscape of High-Grade Neuroendocrine Cervical Carcinoma: Implications for Rethinking Current Treatment Paradigms.

Jco Precision Oncology
Eskander, Ramez N RN; Elvin, Julia J; Gay, Laurie L; Ross, Jeffrey S JS; Miller, Vincent A VA; Kurzrock, Razelle R
Publication Date: 2020

Variant appearance in text: BRAF: I326V
PubMed Link: 33015532
Variant Present in the following documents:
  • PO.19.00248.pdf
View BVdb publication page



Genomic characterization of a newly established esophageal squamous cell carcinoma cell line from China and published esophageal squamous cell carcinoma cell lines.

Cancer Cell International
Li, Xiang X; Tian, Dongping D; Guo, Yi Y; Qiu, Shiyue S; Xu, Zexin Z; Deng, Wen W; Su, Min M
Publication Date: 2020

Variant appearance in text: BRAF: 976A>G; I326V
PubMed Link: 32489320
Variant Present in the following documents:
  • 12935_2020_1268_MOESM8_ESM.xlsx, sheet 1
View BVdb publication page



Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.

Nature Communications
Reitman, Zachary J ZJ; Paolella, Brenton R BR; Bergthold, Guillaume G; Pelton, Kristine K; Becker, Sarah S; Jones, Robert R; Sinai, Claire E CE; Malkin, Hayley H; Huang, Ying Y; Grimmet, Leslie L; Herbert, Zachary T ZT; Sun, Yu Y; Weatherbee, Jessica L JL; Alberta, John A JA; Daley, John F JF; Rozenblatt-Rosen, Orit O; Condurat, Alexandra L AL; Qian, Kenin K; Khadka, Prasidda P; Segal, Rosalind A RA; Haas-Kogan, Daphne D; Filbin, Mariella G MG; Suva, Mario L ML; Regev, Aviv A; Stiles, Charles D CD; Kieran, Mark W MW; Goumnerova, Liliana L; Ligon, Keith L KL; Shalek, Alex K AK; Bandopadhayay, Pratiti P; Beroukhim, Rameen R
Publication Date: 2019-08-19

Variant appearance in text: BRAF: 976A>G
PubMed Link: 31427603
Variant Present in the following documents:
  • 41467_2019_11493_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Mouse avatar models of esophageal squamous cell carcinoma proved the potential for EGFR-TKI afatinib and uncovered Src family kinases involved in acquired resistance.

Journal Of Hematology & Oncology
Liu, Zhentao Z; Chen, Zuhua Z; Wang, Jingyuan J; Zhang, Mengqi M; Li, Zhongwu Z; Wang, Shubin S; Dong, Bin B; Zhang, Cheng C; Gao, Jing J; Shen, Lin L
Publication Date: 2018-08-29

Variant appearance in text: BRAF: I326V
PubMed Link: 30157900
Variant Present in the following documents:
  • Main text
  • 13045_2018_Article_651.pdf
View BVdb publication page



Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports
Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS
Publication Date: 2018-04-03

Variant appearance in text: BRAF: 976A>G
PubMed Link: 29617658
Variant Present in the following documents:
  • NIHMS958974-supplement-5.xlsx, sheet 1
  • NIHMS958974-supplement-6.xlsx, sheet 1
View BVdb publication page



Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.

Oncotarget
Shimada, Yoshifumi Y; Kameyama, Hitoshi H; Nagahashi, Masayuki M; Ichikawa, Hiroshi H; Muneoka, Yusuke Y; Yagi, Ryoma R; Tajima, Yosuke Y; Okamura, Takuma T; Nakano, Masato M; Sakata, Jun J; Kobayashi, Takashi T; Nogami, Hitoshi H; Maruyama, Satoshi S; Takii, Yasumasa Y; Hayashida, Tetsu T; Takaishi, Hiromasa H; Kitagawa, Yuko Y; Oki, Eiji E; Konishi, Tsuyoshi T; Ishida, Fumio F; Kudo, Shin-Ei SE; Ring, Jennifer E JE; Protopopov, Alexei A; Lyle, Stephen S; Ling, Yiwei Y; Okuda, Shujiro S; Ishikawa, Takashi T; Akazawa, Kohei K; Takabe, Kazuaki K; Wakai, Toshifumi T
Publication Date: 2017-11-07

Variant appearance in text: BRAF: I326V
PubMed Link: 29212173
Variant Present in the following documents:
  • oncotarget-08-93567-s003.xlsx, sheet 1
View BVdb publication page



Profiling cancer-related gene mutations in oral squamous cell carcinoma from Japanese patients by targeted amplicon sequencing.

Oncotarget
Nakagaki, Takafumi T; Tamura, Miyuki M; Kobashi, Kenta K; Koyama, Ryota R; Fukushima, Hisayo H; Ohashi, Tomoko T; Idogawa, Masashi M; Ogi, Kazuhiro K; Hiratsuka, Hiroyoshi H; Tokino, Takashi T; Sasaki, Yasushi Y
Publication Date: 2017-08-29

Variant appearance in text: BRAF: Ile326Val
PubMed Link: 28938622
Variant Present in the following documents:
  • oncotarget-08-59113-s006.xlsx, sheet 1
View BVdb publication page



Rare variants analysis of cutaneous malignant melanoma genes in Parkinson's disease.

Neurobiology Of Aging
Lubbe, S J SJ; Escott-Price, V V; Brice, A A; Gasser, T T; Pittman, A M AM; Bras, J J; Hardy, J J; Heutink, P P; Wood, N M NM; Singleton, A B AB; Grosset, D G DG; Carroll, C B CB; Law, M H MH; Demenais, F F; Iles, M M MM; , ; Bishop, D T DT; Newton-Bishop, J J; Williams, N M NM; Morris, H R HR; ,
Publication Date: 2016-12

Variant appearance in text: BRAF: I326V
PubMed Link: 27640074
Variant Present in the following documents:
  • mmc2.xlsx, sheet 5
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: BRAF: 976A>G; I326V
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 3
View BVdb publication page



Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.

Oncotarget
Eisenhardt, Anja E AE; Sprenger, Adrian A; Röring, Michael M; Herr, Ricarda R; Weinberg, Florian F; Köhler, Martin M; Braun, Sandra S; Orth, Joachim J; Diedrich, Britta B; Lanner, Ulrike U; Tscherwinski, Natalja N; Schuster, Simon S; Dumaz, Nicolas N; Schmidt, Enrico E; Baumeister, Ralf R; Schlosser, Andreas A; Dengjel, Jörn J; Brummer, Tilman T
Publication Date: 2016-05-03

Variant appearance in text: BRAF: I326V
PubMed Link: 27034005
Variant Present in the following documents:
  • oncotarget-07-26628-s007.pdf
View BVdb publication page



Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery.

Cancer Research
Hudson, Andrew M AM; Yates, Tim T; Li, Yaoyong Y; Trotter, Eleanor W EW; Fawdar, Shameem S; Chapman, Phil P; Lorigan, Paul P; Biankin, Andrew A; Miller, Crispin J CJ; Brognard, John J
Publication Date: 2014-11-15

Variant appearance in text: BRAF: I326V
PubMed Link: 25256751
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations.

Molecular Systems Biology
Kiel, Christina C; Serrano, Luis L
Publication Date: 2014-05-06

Variant appearance in text: BRAF: I326V
PubMed Link: 24803665
Variant Present in the following documents:
  • MSB-10-5-727-s13.xls, sheet 1
View BVdb publication page



Effect of a poly(ADP-ribose) polymerase-1 inhibitor against esophageal squamous cell carcinoma cell lines.

Cancer Science
Nasuno, Tomomitsu T; Mimaki, Sachiyo S; Okamoto, Makito M; Esumi, Hiroyasu H; Tsuchihara, Katsuya K
Publication Date: 2014-02

Variant appearance in text: BRAF: I326V
PubMed Link: 24219164
Variant Present in the following documents:
  • cas0105-0202-SD2.xlsx, sheet 1
View BVdb publication page



Performance comparison of bench-top next generation sequencers using microdroplet PCR-based enrichment for targeted sequencing in patients with autism spectrum disorder.

Plos One
Koshimizu, Eriko E; Miyatake, Satoko S; Okamoto, Nobuhiko N; Nakashima, Mitsuko M; Tsurusaki, Yoshinori Y; Miyake, Noriko N; Saitsu, Hirotomo H; Matsumoto, Naomichi N
Publication Date: 2013

Variant appearance in text: BRAF: 976A>G; I326V
PubMed Link: 24066114
Variant Present in the following documents:
  • Main text
View BVdb publication page



High accuracy mutation detection in leukemia on a selected panel of cancer genes.

Plos One
Kalender Atak, Zeynep Z; De Keersmaecker, Kim K; Gianfelici, Valentina V; Geerdens, Ellen E; Vandepoel, Roel R; Pauwels, Daphnie D; Porcu, Michaël M; Lahortiga, Idoya I; Brys, Vanessa V; Dirks, Willy G WG; Quentmeier, Hilmar H; Cloos, Jacqueline J; Cuppens, Harry H; Uyttebroeck, Anne A; Vandenberghe, Peter P; Cools, Jan J; Aerts, Stein S
Publication Date: 2012

Variant appearance in text: BRAF: I326V
PubMed Link: 22675565
Variant Present in the following documents:
  • pone.0038463.s007.xlsx, sheet 1
View BVdb publication page