BRAF c.131C>T ;(p.P44L)

Variant ID: 7-140624373-G-A

NM_004333.4(BRAF):c.131C>T;(p.P44L)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


The NHS England 100,000 Genomes Project: feasibility and utility of centralised genome sequencing for children with cancer.

British Journal Of Cancer
Trotman, Jamie J; Armstrong, Ruth R; Firth, Helen H; Trayers, Claire C; Watkins, James J; Allinson, Kieren K; Jacques, Thomas S TS; Nicholson, James C JC; Burke, G A Amos GAA; , ; Behjati, Sam S; Murray, Matthew J MJ; Hook, Catherine E CE; Tarpey, Patrick P
Publication Date: 2022-07

Variant appearance in text: BRAF: 131C>T; Pro44Leu
PubMed Link: 35449451
Variant Present in the following documents:
  • 41416_2022_1788_MOESM4_ESM.pdf
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: BRAF: 131C>T; Pro44Leu
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data2.xlsx, sheet 1
View BVdb publication page



Analysis of the genomic landscape of yolk sac tumors reveals mechanisms of evolution and chemoresistance.

Nature Communications
Zong, Xuan X; Zhang, Ying Y; Peng, Xinxin X; Cao, Dongyan D; Yu, Mei M; Wang, Jinhui J; Li, Hongyue H; Guo, Xuejiao X; Liang, Han H; Yang, Jiaxin J
Publication Date: 2021-06-11

Variant appearance in text: BRAF: P44L
PubMed Link: 34117242
Variant Present in the following documents:
  • 41467_2021_23681_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations.

Nature Communications
Brady, Samuel W SW; Liu, Yanling Y; Ma, Xiaotu X; Gout, Alexander M AM; Hagiwara, Kohei K; Zhou, Xin X; Wang, Jian J; Macias, Michael M; Chen, Xiaolong X; Easton, John J; Mulder, Heather L HL; Rusch, Michael M; Wang, Lu L; Nakitandwe, Joy J; Lei, Shaohua S; Davis, Eric M EM; Naranjo, Arlene A; Cheng, Cheng C; Maris, John M JM; Downing, James R JR; Cheung, Nai-Kong V NV; Hogarty, Michael D MD; Dyer, Michael A MA; Zhang, Jinghui J
Publication Date: 2020-10-14

Variant appearance in text: BRAF: P44L
PubMed Link: 33056981
Variant Present in the following documents:
  • 41467_2020_Article_18987.pdf
View BVdb publication page



Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology
Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M
Publication Date: 2020-01-07

Variant appearance in text: BRAF: 131C>T
PubMed Link: 31925297
Variant Present in the following documents:
  • 42003_2019_736_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Development, Implementation and Assessment of Molecular Diagnostics by Next Generation Sequencing in Personalized Treatment of Cancer: Experience of a Public Reference Healthcare Hospital.

Cancers
Simarro, Javier J; Murria, Rosa R; Pérez-Simó, Gema G; Llop, Marta M; Mancheño, Nuria N; Ramos, David D; Juan, Inmaculada de I; Barragán, Eva E; Laiz, Begoña B; Cases, Enrique E; Ansótegui, Emilio E; Gómez-Codina, José J; Aparicio, Jorge J; Salvador, Carmen C; Juan, Óscar Ó; Palanca, Sarai S
Publication Date: 2019-08-16

Variant appearance in text: BRAF: 131C>T; Pro44Leu
PubMed Link: 31426418
Variant Present in the following documents:
  • cancers-11-01196-s001.pdf
View BVdb publication page



NF1 mutations in conjunctival melanoma.

British Journal Of Cancer
Scholz, S L SL; Cosgarea, I I; Süßkind, D D; Murali, R R; Möller, I I; Reis, H H; Leonardelli, S S; Schilling, B B; Schimming, T T; Hadaschik, E E; Franklin, C C; Paschen, A A; Sucker, A A; Steuhl, K P KP; Schadendorf, D D; Westekemper, H H; Griewank, K G KG
Publication Date: 2018-05

Variant appearance in text: BRAF: Pro44Leu
PubMed Link: 29559732
Variant Present in the following documents:
  • 41416_2018_46_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



The mutational landscape of MYCN, Lin28b and ALK driven murine neuroblastoma mimics human disease.

Oncotarget
De Wilde, Bram B; Beckers, Anneleen A; Lindner, Sven S; Kristina, Althoff A; De Preter, Katleen K; Depuydt, Pauline P; Mestdagh, Pieter P; Sante, Tom T; Lefever, Steve S; Hertwig, Falk F; Peng, Zhiyu Z; Shi, Le-Ming LM; Lee, Sangkyun S; Vandermarliere, Elien E; Martens, Lennart L; Menten, Björn B; Schramm, Alexander A; Fischer, Matthias M; Schulte, Johannes J; Vandesompele, Jo J; Speleman, Frank F
Publication Date: 2018-02-02

Variant appearance in text: BRAF: P44L
PubMed Link: 29492199
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: BRAF: 131C>T
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Cell
Creixell, Pau P; Schoof, Erwin M EM; Simpson, Craig D CD; Longden, James J; Miller, Chad J CJ; Lou, Hua Jane HJ; Perryman, Lara L; Cox, Thomas R TR; Zivanovic, Nevena N; Palmeri, Antonio A; Wesolowska-Andersen, Agata A; Helmer-Citterich, Manuela M; Ferkinghoff-Borg, Jesper J; Itamochi, Hiroaki H; Bodenmiller, Bernd B; Erler, Janine T JT; Turk, Benjamin E BE; Linding, Rune R
Publication Date: 2015-09-24

Variant appearance in text: BRAF: P44L
PubMed Link: 26388441
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page