KCNH2 c.1951_1952delinsTA ;(p.M651*)

Variant ID: 7-150648202-AT-TA

NM_000238.3(KCNH2):c.1951_1952delinsTA;(p.M651*)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Allosteric Coupling Between Drug Binding and the Aromatic Cassette in the Pore Domain of the hERG1 Channel: Implications for a State-Dependent Blockade.

Frontiers In Pharmacology
Kudaibergenova, Meruyert M; Guo, Jiqing J; Khan, Hanif M HM; Zahid, Farhan F; Lees-Miller, James J; Noskov, Sergei Yu SY; Duff, Henry J HJ
Publication Date: 2020

Variant appearance in text: HERG: M651X
PubMed Link: 32694995
Variant Present in the following documents:
  • fphar-11-00914.pdf
View BVdb publication page



The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain.

Molecular Pharmacology
Perissinotti, Laura L; Guo, Jiqing J; Kudaibergenova, Meruyert M; Lees-Miller, James J; Ol'khovich, Marina M; Sharapova, Angelica A; Perlovich, German L GL; Muruve, Daniel A DA; Gerull, Brenda B; Noskov, Sergei Yu SY; Duff, Henry J HJ
Publication Date: 2019-08

Variant appearance in text: Kv11.1: M651X
PubMed Link: 31182542
Variant Present in the following documents:
  • Main text
View BVdb publication page