Publications:

What Is the Potential for Lumacaftor as a Chemical Chaperone in Promoting hERG Trafficking?

Frontiers In Cardiovascular Medicine

Zheng, Zequn Z; Song, Yongfei Y; Lian, Jiangfang J

Publication Date: 2022

Variant appearance in text: KCNH2: T634S

PubMed Link: 35282377

Variant Present in the following documents:

• Main text
• fcvm-09-801927.pdf

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Serine mutation of a conserved threonine in the hERG K+ channel S6-pore region leads to loss-of-function through trafficking impairment.

Biochemical And Biophysical Research Communications

Al-Moubarak, Ehab E; Zhang, Yihong Y; Dempsey, Christopher E CE; Zhang, Henggui H; Harmer, Stephen C SC; Hancox, Jules C JC

Publication Date: 2020-06-11

Variant appearance in text: LQT2: 1901C>G

PubMed Link: 32321643

Variant Present in the following documents:

• Main text
• main.pdf

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