Publications:

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Functional and pharmacological characterization of an S5 domain hERG mutation associated with short QT syndrome.

Heliyon

Butler, Andrew A; Zhang, Yihong Y; Stuart, A Graham AG; Dempsey, Christopher E CE; Hancox, Jules C JC

Publication Date: 2019-04

Variant appearance in text: LQT2: T618A

PubMed Link: 31049424

Variant Present in the following documents:

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Getting to the heart of hERG K(+) channel gating.

The Journal Of Physiology

Perry, Matthew D MD; Ng, Chai-Ann CA; Mann, Stefan A SA; Sadrieh, Arash A; Imtiaz, Mohammad M; Hill, Adam P AP; Vandenberg, Jamie I JI

Publication Date: 2015-06-15

Variant appearance in text: HERG: T618A

PubMed Link: 25820318

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Cooperative subunit interactions mediate fast C-type inactivation of hERG1 K+ channels.

The Journal Of Physiology

Wu, Wei W; Gardner, Alison A; Sanguinetti, Michael C MC

Publication Date: 2014-10-15

Variant appearance in text: KCNH2: T618A

PubMed Link: 25063820

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Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating.

The Journal Of Biological Chemistry

Perry, Matthew D MD; Ng, Chai Ann CA; Vandenberg, Jamie I JI

Publication Date: 2013-04-19

Variant appearance in text: Kv11.1: T618A

PubMed Link: 23471968

Variant Present in the following documents:

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Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway.

The Journal Of Biological Chemistry

Ferrer, Tania T; Cordero-Morales, Julio F JF; Arias, Marcelo M; Ficker, Eckhard E; Medovoy, David D; Perozo, Eduardo E; Tristani-Firouzi, Martin M

Publication Date: 2011-11-11

Variant appearance in text: KCNH2: T618A

PubMed Link: 21908602

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Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide.

Molecular Pharmacology

Garg, Vivek V; Stary-Weinzinger, Anna A; Sachse, Frank F; Sanguinetti, Michael C MC

Publication Date: 2011-10

Variant appearance in text: KCNH2: T618A

PubMed Link: 21743002

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Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.

Molecular Pharmacology

Grunnet, Morten M; Abbruzzese, Jennifer J; Sachse, Frank B FB; Sanguinetti, Michael C MC

Publication Date: 2011-01

Variant appearance in text: LQT2: T618A

PubMed Link: 20876384

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