KCNH2 c.1565G>C ;(p.G522A)

Variant ID: 7-150648916-C-G

NM_000238.3(KCNH2):c.1565G>C;(p.G522A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization.

Bmc Molecular And Cell Biology
Matsumura, Kazuki K; Shimomura, Takushi T; Kubo, Yoshihiro Y; Oka, Takayuki T; Kobayashi, Naohiro N; Imai, Shunsuke S; Yanase, Naomi N; Akimoto, Madoka M; Fukuda, Masahiro M; Yokogawa, Mariko M; Ikeda, Kazuyoshi K; Kurita, Jun-Ichi JI; Nishimura, Yoshifumi Y; Shimada, Ichio I; Osawa, Masanori M
Publication Date: 2021-01-07

Variant appearance in text: HERG: G522A
PubMed Link: 33413079
Variant Present in the following documents:
  • 12860_2020_Article_337.pdf
View BVdb publication page



Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3.

Molecular Pharmacology
Gardner, Alison A; Wu, Wei W; Thomson, Steven S; Zangerl-Plessl, Eva-Maria EM; Stary-Weinzinger, Anna A; Sanguinetti, Michael C MC
Publication Date: 2017-10

Variant appearance in text: KCNH2: G522A
PubMed Link: 28705808
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.

The Journal Of General Physiology
Perry, Matthew D MD; Wong, Sophia S; Ng, Chai Ann CA; Vandenberg, Jamie I JI
Publication Date: 2013-09

Variant appearance in text: Kv11.1: G522A
PubMed Link: 23980196
Variant Present in the following documents:
  • supp_jgp.201310975_JGP_201310975_sm.pdf
View BVdb publication page