KCNH2 c.847T>G ;(p.S283A)

Variant ID: 7-150655216-A-C

NM_000238.3(KCNH2):c.847T>G;(p.S283A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Mechanisms underlying the protein-kinase mediated regulation of the HERG potassium channel synthesis.

Biochimica Et Biophysica Acta
Krishnan, Yamini Y; Li, Yan Y; Zheng, Renjian R; Kanda, Vikram V; McDonald, Thomas V TV
Publication Date: 2012-08

Variant appearance in text: HERG: S283A
PubMed Link: 22613764
Variant Present in the following documents:
  • Main text
View BVdb publication page



PKA phosphorylation of HERG protein regulates the rate of channel synthesis.

American Journal Of Physiology. Heart And Circulatory Physiology
Chen, Jian J; Sroubek, Jakub J; Krishnan, Yamini Y; Li, Yan Y; Bian, Jinsong J; McDonald, Thomas V TV
Publication Date: 2009-05

Variant appearance in text: HERG: S283A
PubMed Link: 19234087
Variant Present in the following documents:
  • Main text
View BVdb publication page



14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity.

The Embo Journal
Kagan, Anna A; Melman, Yonathan F YF; Krumerman, Andrew A; McDonald, Thomas V TV
Publication Date: 2002-04-15

Variant appearance in text: HERG: S283A
PubMed Link: 11953308
Variant Present in the following documents:
  • Main text
View BVdb publication page