KCNH2 c.58_59delinsGC ;(p.R20A)

Variant ID: 7-150674943-CG-GC

NM_000238.3(KCNH2):c.58_59delinsGC;(p.R20A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Open conformation of hERG channel turrets revealed by a specific scorpion toxin BmKKx2.

Cell & Bioscience
Hu, You-Tian YT; Hu, Jun J; Li, Tian T; Wei, Jing-Jing JJ; Feng, Jing J; Du, Yi-Mei YM; Cao, Zhi-Jian ZJ; Li, Wen-Xin WX; Wu, Ying-Liang YL
Publication Date: 2014

Variant appearance in text: HERG: R20A
PubMed Link: 24725272
Variant Present in the following documents:
  • 2045-3701-4-18.pdf
View BVdb publication page



Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels.

The Journal Of General Physiology
Tan, Peter S PS; Perry, Matthew D MD; Ng, Chai Ann CA; Vandenberg, Jamie I JI; Hill, Adam P AP
Publication Date: 2012-09

Variant appearance in text: HERG: R20A
PubMed Link: 22891279
Variant Present in the following documents:
  • supp_jgp.201110761_JGP_201110761_sm.pdf
View BVdb publication page



Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BK(Ca) channel.

The Journal Of General Physiology
Pantazis, Antonios A; Kohanteb, Azadeh P AP; Olcese, Riccardo R
Publication Date: 2010-12

Variant appearance in text: HERG: R20A
PubMed Link: 21078868
Variant Present in the following documents:
  • JGP_201010503.pdf
View BVdb publication page



Probing the outer mouth structure of the HERG channel with peptide toxin footprinting and molecular modeling.

Biophysical Journal
Tseng, Gea-Ny GN; Sonawane, Kailas D KD; Korolkova, Yuliya V YV; Zhang, Mei M; Liu, Jie J; Grishin, Eugene V EV; Guy, H Robert HR
Publication Date: 2007-05-15

Variant appearance in text: HERG: R20A
PubMed Link: 17293393
Variant Present in the following documents:
  • Main text
View BVdb publication page