IGFBP3 c.*1195A>T

Variant ID: 7-45952254-T-A

NM_000598.5(IGFBP3):c.*1195A>T

This variant was identified in 22 publications

View GRCh38 version.




Publications:


Beneficial effects of mifepristone treatment in breast cancer patients selected by the progesterone receptor isoform ratio: Results from the MIPRA trial.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Elía, Andrés A; Saldain, Leo L; Vanzulli, Silvia I SI; Helguero, Luisa A LA; Lamb, Caroline A CA; Fabris, Victoria V; Pataccini, Gabriela G; Martínez-Vazquez, Paula P; Burruchaga, Javier J; Caillet-Bois, Ines I; Spengler, Eunice E; Acosta Haab, Gabriela G; Liguori, Marcos M; Castets, Alejandra A; Lovisi, Silvia S; Abascal, María F MF; Novaro, Virginia V; Sánchez, Jana J; Muñoz, Javier J; Belizán, Jose M JM; Abba, Martín C MC; Gass, Hugo H; Rojas, Paola P; Lanari, Claudia C
Publication Date: 2022-10-21

Variant appearance in text: rs6670
PubMed Link: 36269797
Variant Present in the following documents:
  • ccr-22-2060_supplementary_table_s5_suppts5.xlsx, sheet 1
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Annotating Transcriptional Effects of Genetic Variants in Disease-Relevant Tissue: Transcriptome-Wide Allelic Imbalance in Osteoarthritic Cartilage.

Arthritis & Rheumatology (Hoboken, N.J.)
den Hollander, Wouter W; Pulyakhina, Irina I; Boer, Cindy C; Bomer, Nils N; van der Breggen, Ruud R; Arindrarto, Wibowo W; Couthino de Almeida, Rodrigo R; Lakenberg, Nico N; Sentner, Thom T; Laros, Jeroen F J JFJ; 't Hoen, Peter A C PAC; Slagboom, Eline P E EPE; Nelissen, Rob G H H RGHH; van Meurs, Joyce J; Ramos, Yolande F M YFM; Meulenbelt, Ingrid I
Publication Date: 2019-04

Variant appearance in text: rs6670
PubMed Link: 30298554
Variant Present in the following documents:
  • Main text
  • ART-71-561.pdf
  • ART-71-561-s011.pdf
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Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples.

Oncotarget
Ma, Shiyong S; Menon, Ranjeeta R; Poulos, Rebecca C RC; Wong, Jason W H JWH
Publication Date: 2017-11-10

Variant appearance in text: rs6670
PubMed Link: 29221171
Variant Present in the following documents:
  • oncotarget-08-95841-s002.xlsx, sheet 4
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Polymorphisms of Insulin-Like Growth Factor 1 Pathway Genes and Breast Cancer Risk.

Frontiers In Oncology
Shi, Joy J; Aronson, Kristan J KJ; Grundy, Anne A; Kobayashi, Lindsay C LC; Burstyn, Igor I; Schuetz, Johanna M JM; Lohrisch, Caroline A CA; SenGupta, Sandip K SK; Lai, Agnes S AS; Brooks-Wilson, Angela A; Spinelli, John J JJ; Richardson, Harriet H
Publication Date: 2016

Variant appearance in text: rs6670
PubMed Link: 27376028
Variant Present in the following documents:
  • Main text
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Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels.

International Journal Of Cancer
Bonilla, Carolina C; Lewis, Sarah J SJ; Rowlands, Mari-Anne MA; Gaunt, Tom R TR; Davey Smith, George G; Gunnell, David D; Palmer, Tom T; Donovan, Jenny L JL; Hamdy, Freddie C FC; Neal, David E DE; Eeles, Rosalind R; Easton, Doug D; Kote-Jarai, Zsofia Z; Al Olama, Ali Amin AA; Benlloch, Sara S; Muir, Kenneth K; Giles, Graham G GG; Wiklund, Fredrik F; Grönberg, Henrik H; Haiman, Christopher A CA; Schleutker, Johanna J; Nordestgaard, Børge G BG; Travis, Ruth C RC; Pashayan, Nora N; Khaw, Kay-Tee KT; Stanford, Janet L JL; Blot, William J WJ; Thibodeau, Stephen S; Maier, Christiane C; Kibel, Adam S AS; Cybulski, Cezary C; Cannon-Albright, Lisa L; Brenner, Hermann H; Park, Jong J; Kaneva, Radka R; Batra, Jyotsna J; Teixeira, Manuel R MR; Pandha, Hardev H; , ; Lathrop, Mark M; Martin, Richard M RM; Holly, Jeff M P JM
Publication Date: 2016-10-01

Variant appearance in text: rs6670
PubMed Link: 27225428
Variant Present in the following documents:
  • Main text
  • IJC-139-1520.pdf
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mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer.

Plos One
von der Heyde, Silvia S; Wagner, Steve S; Czerny, Alexander A; Nietert, Manuel M; Ludewig, Fabian F; Salinas-Riester, Gabriela G; Arlt, Dorit D; Beißbarth, Tim T
Publication Date: 2015

Variant appearance in text: rs6670
PubMed Link: 25710561
Variant Present in the following documents:
  • Main text
  • pone.0117818.pdf
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Variation in inflammatory cytokine/growth-factor genes and mammographic density in premenopausal women aged 50-55.

Plos One
Ozhand, Ali A; Lee, Eunjung E; Wu, Anna H AH; Ellingjord-Dale, Merete M; Akslen, Lars A LA; McKean-Cowdin, Roberta R; Ursin, Giske G
Publication Date: 2013

Variant appearance in text: rs6670
PubMed Link: 23762340
Variant Present in the following documents:
  • Main text
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Genetic variability in IGF-1 and IGFBP-3 and body size in early life.

Bmc Public Health
Poole, Elizabeth M EM; Tworoger, Shelley S SS; Hankinson, Susan E SE; Baer, Heather J HJ
Publication Date: 2012-08-15

Variant appearance in text: rs6670
PubMed Link: 22894543
Variant Present in the following documents:
  • Main text
  • 1471-2458-12-659.pdf
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HTR1B, ADIPOR1, PPARGC1A, and CYP19A1 and obesity in a cohort of Caucasians and African Americans: an evaluation of gene-environment interactions and candidate genes.

American Journal Of Epidemiology
Edwards, Todd L TL; Velez Edwards, Digna R DR; Villegas, Raquel R; Cohen, Sarah S SS; Buchowski, Maciej S MS; Fowke, Jay H JH; Schlundt, David D; Long, Jirong J; Long, Ji Rong JR; Cai, Qiuyin Q; Zheng, Wei W; Shu, Xiao-Ou XO; Hargreaves, Margaret K MK; Smith, Jeffrey J; Jeffrey, Smith S; Williams, Scott M SM; Signorello, Lisa B LB; Blot, William J WJ; Matthews, Charles E CE
Publication Date: 2012-01-01

Variant appearance in text: rs6670
PubMed Link: 22106445
Variant Present in the following documents:
  • Main text
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Challenges in the association of human single nucleotide polymorphism mentions with unique database identifiers.

Bmc Bioinformatics
Thomas, Philippe E PE; Klinger, Roman R; Furlong, Laura I LI; Hofmann-Apitius, Martin M; Friedrich, Christoph M CM
Publication Date: 2011

Variant appearance in text: rs6670
PubMed Link: 21992066
Variant Present in the following documents:
  • Main text
  • 1471-2105-12-S4-S4.pdf
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Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.

International Journal Of Molecular Epidemiology And Genetics
Ricketts, Sally L SL; Rensing, Katrijn L KL; Holly, Jeff M JM; Chen, Li L; Young, Elizabeth H EH; Luben, Robert R; Ashford, Sofie S; Song, Kijoung K; Yuan, Xin X; Dehghan, Abbas A; Wright, Benjamin J BJ; Waterworth, Dawn M DM; Mooser, Vincent V; , ; Waeber, Gérard G; Vollenweider, Peter P; Epstein, Stephen E SE; Burnett, Mary S MS; Devaney, Joseph M JM; Hakonarson, Hakon H HH; Rader, Daniel J DJ; Reilly, Muredach P MP; Danesh, John J; Thompson, Simon G SG; Dunning, Alison M AM; van Duijn, Cornelia M CM; Samani, Nilesh J NJ; McPherson, Ruth R; Wareham, Nicholas J NJ; Khaw, Kay-Tee KT; Boekholdt, S Matthijs SM; Sandhu, Manjinder S MS
Publication Date: 2011-08-30

Variant appearance in text: rs6670
PubMed Link: 21915365
Variant Present in the following documents:
  • Main text
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Common genetic variation within IGFI, IGFII, IGFBP-1, and IGFBP-3 and endometrial cancer risk.

Gynecologic Oncology
McGrath, Monica M; Lee, I-Min IM; Buring, Julie J; De Vivo, Immaculata I
Publication Date: 2011-02

Variant appearance in text: rs6670
PubMed Link: 21078522
Variant Present in the following documents:
  • Main text
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A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians.

Human Molecular Genetics
Schumacher, Fredrick R FR; Cheng, Iona I; Freedman, Matthew L ML; Mucci, Lorelei L; Allen, Naomi E NE; Pollak, Michael N MN; Hayes, Richard B RB; Stram, Daniel O DO; Canzian, Federico F; Henderson, Brian E BE; Hunter, David J DJ; Virtamo, Jarmo J; Manjer, Jonas J; Gaziano, J Michael JM; Kolonel, Laurence N LN; Tjønneland, Anne A; Albanes, Demetrius D; Calle, Eugenia E EE; Giovannucci, Edward E; Crawford, E David ED; Haiman, Christopher A CA; Kraft, Peter P; Willett, Walter C WC; Thun, Michael J MJ; Le Marchand, Loïc L; Kaaks, Rudolf R; Feigelson, Heather Spencer HS; Bueno-de-Mesquita, H Bas HB; Palli, Domenico D; Riboli, Elio E; Lund, Eiliv E; Amiano, Pilar P; Andriole, Gerald G; Dunning, Alison M AM; Trichopoulos, Dimitrios D; Stampfer, Meir J MJ; Key, Timothy J TJ; Ma, Jing J
Publication Date: 2010-08-01

Variant appearance in text: rs6670
PubMed Link: 20484221
Variant Present in the following documents:
  • Main text
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Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.

American Journal Of Medical Genetics. Part A
Ester, Audrey R AR; Weymouth, Katelyn S KS; Burt, Amber A; Wise, Carol A CA; Scott, Allison A; Gurnett, Christina A CA; Dobbs, Matthew B MB; Blanton, Susan H SH; Hecht, Jacqueline T JT
Publication Date: 2009-12

Variant appearance in text: rs6670
PubMed Link: 19938081
Variant Present in the following documents:
  • Main text
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Common genetic variation in IGF1, IGFBP1 and IGFBP3 and ovarian cancer risk.

Carcinogenesis
Terry, Kathryn L KL; Tworoger, Shelley S SS; Gates, Margaret A MA; Cramer, Daniel W DW; Hankinson, Susan E SE
Publication Date: 2009-12

Variant appearance in text: rs6670
PubMed Link: 19858071
Variant Present in the following documents:
  • Main text
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An analysis of growth, differentiation and apoptosis genes with risk of renal cancer.

Plos One
Dong, Linda M LM; Brennan, Paul P; Karami, Sara S; Hung, Rayjean J RJ; Menashe, Idan I; Berndt, Sonja I SI; Yeager, Meredith M; Chanock, Stephen S; Zaridze, David D; Matveev, Vsevolod V; Janout, Vladimir V; Kollarova, Hellena H; Bencko, Vladimir V; Schwartz, Kendra K; Davis, Faith F; Navratilova, Marie M; Szeszenia-Dabrowska, Neonila N; Mates, Dana D; Colt, Joanne S JS; Holcatova, Ivana I; Boffetta, Paolo P; Rothman, Nathaniel N; Chow, Wong-Ho WH; Rosenberg, Philip S PS; Moore, Lee E LE
Publication Date: 2009-03-24

Variant appearance in text: rs6670
PubMed Link: 19603096
Variant Present in the following documents:
  • Main text
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Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease.

International Journal Of Cancer
Su, Xuefen X; Colditz, Graham A GA; Willett, Walter C WC; Collins, Laura C LC; Schnitt, Stuart J SJ; Connolly, James L JL; Pollak, Michael N MN; Rosner, Bernard B; Tamimi, Rulla M RM
Publication Date: 2010-01-01

Variant appearance in text: rs6670
PubMed Link: 19551864
Variant Present in the following documents:
  • Main text
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Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.

Aging Cell
Pawlikowska, Ludmila L; Hu, Donglei D; Huntsman, Scott S; Sung, Andrew A; Chu, Catherine C; Chen, Justin J; Joyner, Alexander H AH; Schork, Nicholas J NJ; Hsueh, Wen-Chi WC; Reiner, Alexander P AP; Psaty, Bruce M BM; Atzmon, Gil G; Barzilai, Nir N; Cummings, Steven R SR; Browner, Warren S WS; Kwok, Pui-Yan PY; Ziv, Elad E; ,
Publication Date: 2009-08

Variant appearance in text: rs6670
PubMed Link: 19489743
Variant Present in the following documents:
  • Main text
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IGF-I and IGFBP-3 polymorphisms in relation to circulating levels among African American and Caucasian women.

Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
D'Aloisio, Aimee A AA; Schroeder, Jane C JC; North, Kari E KE; Poole, Charles C; West, Suzanne L SL; Travlos, Gregory S GS; Baird, Donna D DD
Publication Date: 2009-03

Variant appearance in text: rs6670
PubMed Link: 19240240
Variant Present in the following documents:
  • Main text
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IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).

Plos One
Patel, Alpa V AV; Cheng, Iona I; Canzian, Federico F; Le Marchand, Loïc L; Thun, Michael J MJ; Berg, Christine D CD; Buring, Julie J; Calle, Eugenia E EE; Chanock, Stephen S; Clavel-Chapelon, Francoise F; Cox, David G DG; Dorronsoro, Miren M; Dossus, Laure L; Haiman, Christopher A CA; Hankinson, Susan E SE; Henderson, Brian E BE; Hoover, Robert R; Hunter, David J DJ; Kaaks, Rudolf R; Kolonel, Laurence N LN; Kraft, Peter P; Linseisen, Jakob J; Lund, Eiliv E; Manjer, Jonas J; McCarty, Catherine C; Peeters, Petra H M PH; Pike, Malcolm C MC; Pollak, Michael M; Riboli, Elio E; Stram, Daniel O DO; Tjonneland, Anne A; Travis, Ruth C RC; Trichopoulos, Dimitrios D; Tumino, Rosario R; Yeager, Meredith M; Ziegler, Regina G RG; Feigelson, Heather Spencer HS; ,
Publication Date: 2008-07-02

Variant appearance in text: rs6670
PubMed Link: 18596909
Variant Present in the following documents:
  • Main text
View BVdb publication page



Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study.

Breast Cancer Research : Bcr
Tamimi, Rulla M RM; Cox, David G DG; Kraft, Peter P; Pollak, Michael N MN; Haiman, Christopher A CA; Cheng, Iona I; Freedman, Matthew L ML; Hankinson, Susan E SE; Hunter, David J DJ; Colditz, Graham A GA
Publication Date: 2007

Variant appearance in text: rs6670
PubMed Link: 17300730
Variant Present in the following documents:
  • Main text
  • bcr1655.pdf
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Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC study.

British Journal Of Cancer
Canzian, F F; McKay, J D JD; Cleveland, R J RJ; Dossus, L L; Biessy, C C; Rinaldi, S S; Landi, S S; Boillot, C C; Monnier, S S; Chajès, V V; Clavel-Chapelon, F F; Téhard, B B; Chang-Claude, J J; Linseisen, J J; Lahmann, P H PH; Pischon, T T; Trichopoulos, D D; Trichopoulou, A A; Zilis, D D; Palli, D D; Tumino, R R; Vineis, P P; Berrino, F F; Bueno-de-Mesquita, H B HB; van Gils, C H CH; Peeters, P H M PH; Pera, G G; Ardanaz, E E; Chirlaque, M-D MD; Quirós, J R JR; Larrañaga, N N; Martínez-García, C C; Allen, N E NE; Key, T J TJ; Bingham, S A SA; Khaw, K-T KT; Slimani, N N; Norat, T T; Riboli, E E; Kaaks, R R
Publication Date: 2006-01-30

Variant appearance in text: rs6670
PubMed Link: 16404426
Variant Present in the following documents:
  • Main text
  • 94-6602936a.pdf
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