EGFR c.86A>G ;(p.K29R)

Variant ID: 7-55087056-A-G

NM_005228.3(EGFR):c.86A>G;(p.K29R)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells.

Cell Death & Disease
Seo, Seung Un SU; Woo, Seon Min SM; Im, Seung-Soon SS; Jang, Younghoon Y; Han, Eugene E; Kim, Sang Hyun SH; Lee, Hongchan H; Lee, Hyun-Shik HS; Nam, Ju-Ock JO; Gabrielson, Edward E; Min, Kyoung-Jin KJ; Kwon, Taeg Kyu TK
Publication Date: 2022-02-04

Variant appearance in text: EGFR: K29R
PubMed Link: 35121737
Variant Present in the following documents:
  • Main text
  • 41419_2022_Article_4581.pdf
View BVdb publication page



Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells.

Cell Death & Disease
Seo, Seung Un SU; Woo, Seon Min SM; Im, Seung-Soon SS; Jang, Younghoon Y; Han, Eugene E; Kim, Sang Hyun SH; Lee, Hongchan H; Lee, Hyun-Shik HS; Nam, Ju-Ock JO; Gabrielson, Edward E; Min, Kyoung-Jin KJ; Kwon, Taeg Kyu TK
Publication Date: 2022-02-04

Variant appearance in text: EGFR: K29R
PubMed Link: 35121737
Variant Present in the following documents:
  • Main text
  • 41419_2022_Article_4581.pdf
View BVdb publication page



OTUD7B Deubiquitinates LSD1 to Govern Its Binding Partner Specificity, Homeostasis, and Breast Cancer Metastasis.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Gong, Zhicheng Z; Li, Aicun A; Ding, Jiancheng J; Li, Qing Q; Zhang, Lei L; Li, Yuanpei Y; Meng, Zhe Z; Chen, Fei F; Huang, Jialiang J; Zhou, Dawang D; Hu, Ronggui R; Ye, Jing J; Liu, Wen W; You, Han H
Publication Date: 2021-08

Variant appearance in text: EGFR: K29R
PubMed Link: 34050636
Variant Present in the following documents:
  • ADVS-8-2004504.pdf
View BVdb publication page



Mdm2-Mediated Downmodulation of GRK2 Restricts Centrosome Separation for Proper Chromosome Congression.

Cells
Reglero, Clara C; Ortiz Del Castillo, Belén B; Rivas, Verónica V; Mayor, Federico F; Penela, Petronila P
Publication Date: 2021-03-25

Variant appearance in text: EGFR: K29R
PubMed Link: 33806062
Variant Present in the following documents:
  • Main text
  • cells-10-00729.pdf
View BVdb publication page



Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth.

Autophagy
Feng, Xing X; Jia, Yanyan Y; Zhang, Yuyu Y; Ma, Fei F; Zhu, Yuekun Y; Hong, Xuehui X; Zhou, Qingxin Q; He, Ruixing R; Zhang, Heng H; Jin, Junfei J; Piao, Daxun D; Huang, He H; Li, Qinghua Q; Qiu, Xingfeng X; Zhang, Zhiyong Z
Publication Date: 2019-07

Variant appearance in text: EGFR: K29R
PubMed Link: 30686098
Variant Present in the following documents:
  • Main text
  • kaup-15-07-1570063.pdf
View BVdb publication page



TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Nature
Wang, Bin B; Jie, Zuliang Z; Joo, Donghyun D; Ordureau, Alban A; Liu, Pengda P; Gan, Wenjian W; Guo, Jianping J; Zhang, Jinfang J; North, Brian J BJ; Dai, Xiangpeng X; Cheng, Xuhong X; Bian, Xiuwu X; Zhang, Lingqiang L; Harper, J Wade JW; Sun, Shao-Cong SC; Wei, Wenyi W
Publication Date: 2017-05-18

Variant appearance in text: EGFR: K29R
PubMed Link: 28489822
Variant Present in the following documents:
  • Main text
View BVdb publication page



SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling.

Cell Research
Wang, Feng F; Fu, Xing X; Chen, Peng P; Wu, Ping P; Fan, Xiaojuan X; Li, Na N; Zhu, Hong H; Jia, Ting-Ting TT; Ji, Hongbin H; Wang, Zefeng Z; Wong, Catherine C L CC; Hu, Ronggui R; Hui, Jingyi J
Publication Date: 2017-04

Variant appearance in text: EGFR: K29R
PubMed Link: 28084329
Variant Present in the following documents:
  • Main text
View BVdb publication page



Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis.

The Journal Of Cell Biology
Kumar, K G Suresh KG; Barriere, Hervé H; Carbone, Christopher J CJ; Liu, Jianghuai J; Swaminathan, Gayathri G; Xu, Ping P; Li, Ying Y; Baker, Darren P DP; Peng, Junmin J; Lukacs, Gergely L GL; Fuchs, Serge Y SY
Publication Date: 2007-12-03

Variant appearance in text: EGFR: K29R
PubMed Link: 18056411
Variant Present in the following documents:
  • Main text
  • jcb1790935.pdf
View BVdb publication page



Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome.

The Journal Of Cell Biology
Bilodeau, Patricia S PS; Winistorfer, Stanley C SC; Kearney, William R WR; Robertson, Andrew D AD; Piper, Robert C RC
Publication Date: 2003-10-27

Variant appearance in text: EGFR: K29R
PubMed Link: 14581452
Variant Present in the following documents:
  • 200305007.pdf
View BVdb publication page