EGFR c.866C>T ;(p.A289V)

Variant ID: 7-55221822-C-T

NM_005228.3(EGFR):c.866C>T;(p.A289V)

This variant was identified in 210 publications

View GRCh38 version.




Publications:


The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden.

Journal Of Translational Medicine
Díaz de Ståhl, Teresita T; Shamikh, Alia A; Mayrhofer, Markus M; Juhos, Szilvester S; Basmaci, Elisa E; Prochazka, Gabriela G; Garcia, Maxime M; Somarajan, Praveen Raj PR; Zielinska-Chomej, Katarzyna K; Illies, Christopher C; Øra, Ingrid I; Siesjö, Peter P; Sandström, Per-Erik PE; Stenman, Jakob J; Sabel, Magnus M; Gustavsson, Bengt B; Kogner, Per P; Pfeifer, Susan S; Ljungman, Gustaf G; Sandgren, Johanna J; Nistér, Monica M
Publication Date: 2023-05-23

Variant appearance in text: EGFR: Ala289Val
PubMed Link: 37221626
Variant Present in the following documents:
  • 12967_2023_4178_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



P16 immunohistochemistry is a sensitive and specific surrogate marker for CDKN2A homozygous deletion in gliomas.

Acta Neuropathologica Communications
Vij, Meenakshi M; Cho, Benjamin B BB; Yokoda, Raquel T RT; Rashidipour, Omid O; Umphlett, Melissa M; Richardson, Timothy E TE; Tsankova, Nadejda M NM
Publication Date: 2023-05-03

Variant appearance in text: EGFR: A289V
PubMed Link: 37138345
Variant Present in the following documents:
  • 40478_2023_1573_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: EGFR: A289V
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 4
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology
Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS
Publication Date: 2023

Variant appearance in text: EGFR: A289V
PubMed Link: 36950276
Variant Present in the following documents:
  • Main text
  • 10.1177_17588359231160141.pdf
View BVdb publication page



Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.

Nature Medicine
Sturm, Dominik D; Capper, David D; Andreiuolo, Felipe F; Gessi, Marco M; Kölsche, Christian C; Reinhardt, Annekathrin A; Sievers, Philipp P; Wefers, Annika K AK; Ebrahimi, Azadeh A; Suwala, Abigail K AK; Gielen, Gerrit H GH; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Hovestadt, Volker V; Daenekas, Bjarne B; Rode, Agata A; Hamelmann, Stefan S; Previti, Christopher C; Jäger, Natalie N; Buchhalter, Ivo I; Blattner-Johnson, Mirjam M; Jones, Barbara C BC; Warmuth-Metz, Monika M; Bison, Brigitte B; Grund, Kerstin K; Sutter, Christian C; Hirsch, Steffen S; Dikow, Nicola N; Hasselblatt, Martin M; Schüller, Ulrich U; Gerber, Nicolas U NU; White, Christine L CL; Buntine, Molly K MK; Kinross, Kathryn K; Algar, Elizabeth M EM; Hansford, Jordan R JR; Gottardo, Nicholas G NG; Hernáiz Driever, Pablo P; Gnekow, Astrid A; Witt, Olaf O; Müller, Hermann L HL; Calaminus, Gabriele G; Fleischhack, Gudrun G; Kordes, Uwe U; Mynarek, Martin M; Rutkowski, Stefan S; Frühwald, Michael C MC; Kramm, Christof M CM; von Deimling, Andreas A; Pietsch, Torsten T; Sahm, Felix F; Pfister, Stefan M SM; Jones, David T W DTW
Publication Date: 2023-03-16

Variant appearance in text: EGFR: A289V
PubMed Link: 36928815
Variant Present in the following documents:
  • 41591_2023_2255_MOESM3_ESM.xlsx, sheet 5
View BVdb publication page



Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma.

Genome Medicine
Nam, Yoonhee Y; Koo, Harim H; Yang, Yingxi Y; Shin, Sang S; Zhu, Zhihan Z; Kim, Donggeon D; Cho, Hee Jin HJ; Mu, Quanhua Q; Choi, Seung Won SW; Sa, Jason K JK; Seo, Yun Jee YJ; Kim, Yejin Y; Lee, Kyoungmin K; Oh, Jeong-Woo JW; Kwon, Yong-Jun YJ; Park, Woong-Yang WY; Kong, Doo-Sik DS; Seol, Ho Jun HJ; Lee, Jung-Il JI; Park, Chul-Kee CK; Lee, Hye Won HW; Yoon, Yeup Y; Wang, Jiguang J
Publication Date: 2023-03-13

Variant appearance in text: EGFR: A289V
PubMed Link: 36915208
Variant Present in the following documents:
  • 13073_2023_1165_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



Genomics-Driven Precision Medicine in Pediatric Solid Tumors.

Cancers
Suthapot, Praewa P; Chiangjong, Wararat W; Chaiyawat, Parunya P; Choochuen, Pongsakorn P; Pruksakorn, Dumnoensun D; Sangkhathat, Surasak S; Hongeng, Suradej S; Anurathapan, Usanarat U; Chutipongtanate, Somchai S
Publication Date: 2023-02-23

Variant appearance in text: EGFR: A289V
PubMed Link: 36900212
Variant Present in the following documents:
  • Main text
  • cancers-15-01418.pdf
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: EGFR: 866C>T; Ala289Val
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Combined KRAS G12C and SOS1 inhibition enhances and extends the anti-tumor response in KRAS G12C -driven cancers by addressing intrinsic and acquired resistance.

Biorxiv : The Preprint Server For Biology
Thatikonda, Venu V; Lu, Hengyu H; Jurado, Sabine S; Kostyrko, Kaja K; Bristow, Christopher A CA; Bosch, Karin K; Feng, Ningping N; Gao, Sisi S; Gerlach, Daniel D; Gmachl, Michael M; Lieb, Simone S; Jeschko, Astrid A; Machado, Annette A AA; Marszalek, Ethan D ED; Mahendra, Mikhila M; Jaeger, Philipp A PA; Sorokin, Alexey A; Strauss, Sandra S; Trapani, Francesca F; Kopetz, Scott S; Vellano, Christopher P CP; Petronczki, Mark M; Kraut, Norbert N; Heffernan, Timothy P TP; Marszalek, Joseph R JR; Pearson, Mark M; Waizenegger, Irene I; Hofmann, Marco H MH
Publication Date: 2023-01-23

Variant appearance in text: EGFR: A289V
PubMed Link: 36747713
Variant Present in the following documents:
  • media-1.xlsx, sheet 4
View BVdb publication page



Pediatric diffuse midline glioma H3K27- altered: A complex clinical and biological landscape behind a neatly defined tumor type.

Frontiers In Oncology
Vallero, Stefano Gabriele SG; Bertero, Luca L; Morana, Giovanni G; Sciortino, Paola P; Bertin, Daniele D; Mussano, Anna A; Ricci, Federica Silvia FS; Peretta, Paola P; Fagioli, Franca F
Publication Date: 2022

Variant appearance in text: EGFR: A289V
PubMed Link: 36727064
Variant Present in the following documents:
  • Main text
  • fonc-12-1082062.pdf
View BVdb publication page



Clinical outcome of Brazilian patients with non-small cell lung cancer in early stage harboring rare mutations in epidermal growth factor receptor.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
Machado-Rugolo, J J; Baldavira, C M CM; Prieto, T G TG; Olivieri, E H R EHR; Fabro, A T AT; Rainho, C A CA; Castelli, E C EC; Ribolla, P E M PEM; Ab'Saber, A M AM; Takagaki, T T; Nagai, M A MA; Capelozzi, V L VL
Publication Date: 2023

Variant appearance in text: EGFR: 866C>T; A289V; rs149840192
PubMed Link: 36629526
Variant Present in the following documents:
  • Main text
  • 1414-431X-bjmbr-55-e12409.pdf
View BVdb publication page



Pan-cancer molecular analysis of EGFR large fragment deletion in the Asian population.

Cancer Medicine
Pu, Jun J; Guo, Huannan H; Yu, Ruoying R; Ou, Qiuxiang Q; Bao, Hua H; Wu, Xue X; Tang, Sanyuan S; Chang, Qingyong Q
Publication Date: 2023-01-09

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 36622089
Variant Present in the following documents:
  • CAM4-12-8083-s003.xlsx, sheet 1
View BVdb publication page



Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan.

Cancer Science
Kage, Hidenori H; Shinozaki-Ushiku, Aya A; Ishigaki, Kazunaga K; Sato, Yusuke Y; Tanabe, Masahiko M; Tanaka, Shota S; Tanikawa, Michihiro M; Watanabe, Kousuke K; Kato, Shingo S; Akagi, Kiwamu K; Uchino, Keita K; Mitani, Kinuko K; Takahashi, Shunji S; Miura, Yuji Y; Ikeda, Sadakatsu S; Kojima, Yasushi Y; Watanabe, Kiyotaka K; Mochizuki, Hitoshi H; Yamaguchi, Hironori H; Kawazoe, Yoshimasa Y; Kashiwabara, Kosuke K; Kohsaka, Shinji S; Tatsuno, Kenji K; Ushiku, Tetsuo T; Ohe, Kazuhiko K; Yatomi, Yutaka Y; Seto, Yasuyuki Y; Aburatani, Hiroyuki H; Mano, Hiroyuki H; Miyagawa, Kiyoshi K; Oda, Katsutoshi K
Publication Date: 2023-01-05

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 36601953
Variant Present in the following documents:
  • CAS-114-1710-s001.xlsx, sheet 1
View BVdb publication page



Impact of EGFRA289T/V mutation on relapse pattern in glioblastoma.

Esmo Open
Noeuveglise, A A; Sarafan-Vasseur, N N; Beaussire, L L; Marguet, F F; Modzelewski, R R; Hanzen, C C; Alexandru, C C; Magne, N N; Langlois, O O; Di Fiore, F F; Clatot, F F; Thureau, S S; Fontanilles, M M
Publication Date: 2022-12-22

Variant appearance in text: EGFR: A289V
PubMed Link: 36566697
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: EGFR: A289V
PubMed Link: 36561320
Variant Present in the following documents:
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 4
View BVdb publication page



A prognostic risk model for glioma patients by systematic evaluation of genomic variations.

Iscience
Zhang, Baifeng B; Wan, Weiqing W; Li, Zibo Z; Gao, Zhixian Z; Ji, Nan N; Xie, Jian J; Wang, Junmei J; Wang, Bin B; Lai-Wan Kwong, Dora D; Guan, Xinyuan X; Gao, Shengjie S; Zhao, Yuanli Y; Lu, Youyong Y; Zhang, Liwei L; Rodland, Karin D KD; Tsang, Shirley X SX
Publication Date: 2022-12-22

Variant appearance in text: rs149840192
PubMed Link: 36536675
Variant Present in the following documents:
  • mmc3.xls, sheet 1
View BVdb publication page



An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology
Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y
Publication Date: 2022

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 36505399
Variant Present in the following documents:
  • Table_2.xlsx, sheet 2
View BVdb publication page



Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.

Jama Network Open
Naito, Yoichi Y; Sunami, Kuniko K; Kage, Hidenori H; Komine, Keigo K; Amano, Toraji T; Imai, Mitsuho M; Koyama, Takafumi T; Ennishi, Daisuke D; Kanai, Masashi M; Kenmotsu, Hirotsugu H; Maeda, Takahiro T; Morita, Sachi S; Sakai, Daisuke D; Watanabe, Kousuke K; Shirota, Hidekazu H; Kinoshita, Ichiro I; Yoshioka, Masashiro M; Mamesaya, Nobuaki N; Ito, Mamoru M; Kohsaka, Shinji S; Saigusa, Yusuke Y; Yamamoto, Kouji K; Hirata, Makoto M; Tsuchihara, Katsuya K; Yoshino, Takayuki T
Publication Date: 2022-12-01

Variant appearance in text: EGFR: A289V
PubMed Link: 36469316
Variant Present in the following documents:
  • Main text
View BVdb publication page



Real-world treatment and prognostic factors for survival in ALK+ non-small cell lung cancer (NSCLC) patients with brain metastases in China.

Thoracic Cancer
Li, Na N; Xie, Mingying M; Zhou, Zichao Z; Sheng, Jiamin J; Yu, Xiaoqing X; Fan, Yun Y
Publication Date: 2022-11-21

Variant appearance in text: EGFR: A289V
PubMed Link: 36411716
Variant Present in the following documents:
  • Main text
  • TCA-14-237.pdf
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: EGFR: A289V
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics
Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q
Publication Date: 2022-11-04

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 36333792
Variant Present in the following documents:
  • 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Comparative kinase and cancer cell panel profiling of kinase inhibitors approved for clinical use from 2018 to 2020.

Frontiers In Oncology
Kooijman, Jeffrey J JJ; van Riel, Wilhelmina E WE; Dylus, Jelle J; Prinsen, Martine B W MBW; Grobben, Yvonne Y; de Bitter, Tessa J J TJJ; van Doornmalen, Antoon M AM; Melis, Janneke J T M JJTM; Uitdehaag, Joost C M JCM; Narumi, Yugo Y; Kawase, Yusuke Y; de Roos, Jeroen A D M JADM; Willemsen-Seegers, Nicole N; Zaman, Guido J R GJR
Publication Date: 2022

Variant appearance in text: EGFR: A289V
PubMed Link: 36185300
Variant Present in the following documents:
  • Main text
  • fonc-12-953013.pdf
  • Table_4.xlsx, sheet 1
View BVdb publication page



The comparison of cancer gene mutation frequencies in Chinese and U.S. patient populations.

Nature Communications
Ma, Fayang F; Laster, Kyle K; Dong, Zigang Z
Publication Date: 2022-09-26

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 36163440
Variant Present in the following documents:
  • 41467_2022_33351_MOESM10_ESM.xlsx, sheet 5
View BVdb publication page



Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors.

Neuro-Oncology
Kashani, Elham E; Schnidrig, Désirée D; Hashemi Gheinani, Ali A; Ninck, Martina Selina MS; Zens, Philipp P; Maragkou, Theoni T; Baumgartner, Ulrich U; Schucht, Philippe P; Rätsch, Gunnar G; Rubin, Mark A MA; Berezowska, Sabina S; Ng, Charlotte K Y CKY; Vassella, Erik E; ,
Publication Date: 2022-09-17

Variant appearance in text: EGFR: 866C>T; A289V; rs149840192
PubMed Link: 36124685
Variant Present in the following documents:
  • Main text
  • noac220_suppl_supplementary_table_s3.xlsx, sheet 1
  • noac220.pdf
View BVdb publication page



Identification of potential targets of the curcumin analog CCA-1.1 for glioblastoma treatment : integrated computational analysis and in vitro study.

Scientific Reports
Hermawan, Adam A; Wulandari, Febri F; Hanif, Naufa N; Utomo, Rohmad Yudi RY; Jenie, Riris Istighfari RI; Ikawati, Muthi M; Tafrihani, Ahmad Syauqy AS
Publication Date: 2022-08-17

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 35977996
Variant Present in the following documents:
  • 41598_2022_18348_MOESM3_ESM.xlsx, sheet 6
View BVdb publication page



Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.

Nature Communications
Coy, Shannon S; Wang, Shu S; Stopka, Sylwia A SA; Lin, Jia-Ren JR; Yapp, Clarence C; Ritch, Cecily C CC; Salhi, Lisa L; Baker, Gregory J GJ; Rashid, Rumana R; Baquer, Gerard G; Regan, Michael M; Khadka, Prasidda P; Cole, Kristina A KA; Hwang, Jaeho J; Wen, Patrick Y PY; Bandopadhayay, Pratiti P; Santi, Mariarita M; De Raedt, Thomas T; Ligon, Keith L KL; Agar, Nathalie Y R NYR; Sorger, Peter K PK; Touat, Mehdi M; Santagata, Sandro S
Publication Date: 2022-08-16

Variant appearance in text: EGFR: A289V
PubMed Link: 35973991
Variant Present in the following documents:
  • 41467_2022_32430_MOESM17_ESM.xlsx, sheet 12
  • 41467_2022_32430_MOESM17_ESM.xlsx, sheet 31
View BVdb publication page



Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: EGFR: 866C>T; Ala289Val; rs149840192
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma.

Frontiers In Oncology
Huang, Wenda W; Zou, Ling L; Hao, Zhaonian Z; Wang, Baofeng B; Mao, Feng F; Duan, Qiuhong Q; Guo, Dongsheng D
Publication Date: 2022

Variant appearance in text: EGFR: A289V
PubMed Link: 35814475
Variant Present in the following documents:
  • Main text
  • fonc-12-904383.pdf
View BVdb publication page



The High Proportion of Discordant EGFR Mutations among Multiple Lung Tumors.

Cancers
Lee, Hyunwoo H; Park, Jin Hee JH; Han, Joungho J; Shim, Young Mog YM; Kim, Jhingook J; Choi, Yong Soo YS; Kim, Hong Kwan HK; Cho, Jong Ho JH; Choi, Yoon-La YL; Kim, Wan-Seop WS
Publication Date: 2022-06-18

Variant appearance in text: EGFR: A289V
PubMed Link: 35740676
Variant Present in the following documents:
  • Main text
  • cancers-14-03011.pdf
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: EGFR: A289V
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



Distribution and favorable prognostic implication of genomic EGFR alterations in IDH-wildtype glioblastoma.

Cancer Medicine
Higa, Nayuta N; Akahane, Toshiaki T; Hamada, Taiji T; Yonezawa, Hajime H; Uchida, Hiroyuki H; Makino, Ryutaro R; Watanabe, Shoji S; Takajo, Tomoko T; Yokoyama, Seiya S; Kirishima, Mari M; Matsuo, Kei K; Fujio, Shingo S; Hanaya, Ryosuke R; Tanimoto, Akihide A; Yoshimoto, Koji K
Publication Date: 2022-06-13

Variant appearance in text: EGFR: A289V
PubMed Link: 35695190
Variant Present in the following documents:
  • Main text
  • CAM4-12-49.pdf
View BVdb publication page



Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging
Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M
Publication Date: 2022-05-25

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 35613927
Variant Present in the following documents:
  • aging-14-204101-s004.xlsx, sheet 1
View BVdb publication page



Glioblastoma Multiforme With CDKN2A, Loss of PTEN and EGFR Amplification, and Diffuse Distant Organ Metastasis Treated With Six Lines of Therapy: A Case Report and Literature Review.

Cureus
Aslan, Ferit F; Günaydın, Elif E; Yukruk, Fisun F; Güvenç, İnanç İ; Gençler, Onur Serdar OS
Publication Date: 2022-04

Variant appearance in text: EGFR: A289V
PubMed Link: 35518520
Variant Present in the following documents:
  • Main text
  • cureus-0014-00000023796.pdf
View BVdb publication page



Tuberous sclerosis complex: a complex case.

Cold Spring Harbor Molecular Case Studies
Powell, Ryan M RM; Pattison, Sharon S; Moravec, Jiri C JC; Bhat, Basharat B; Guirguis, Nada N; Markie, David D; Jones, Greg T GT; Copedo, Jason J; Print, Cristin G CG; Morison, Ian M IM; Gavryushkin, Alex A; Gray, Bronwyn B; Wyeth, Lisa J LJ; Eccles, Mike R MR; Macaulay, Erin C EC
Publication Date: 2022-04

Variant appearance in text: EGFR: 866C>T; Ala289Val
PubMed Link: 35483879
Variant Present in the following documents:
  • Main text
  • MCS006182Pow.pdf
View BVdb publication page



Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics
Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R
Publication Date: 2022-04-25

Variant appearance in text: EGFR: 866C>T
PubMed Link: 35468810
Variant Present in the following documents:
  • 12920_2022_1235_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Prospective genomically guided identification of "early/evolving" and "undersampled" IDH-wildtype glioblastoma leads to improved clinical outcomes.

Neuro-Oncology
Zhang, Yalan Y; Lucas, Calixto-Hope G CG; Young, Jacob S JS; Morshed, Ramin A RA; McCoy, Lucie L; Oberheim Bush, Nancy Ann NA; Taylor, Jennie W JW; Daras, Mariza M; Butowski, Nicholas A NA; Villanueva-Meyer, Javier E JE; Cha, Soonmee S; Wrensch, Margaret M; Wiencke, John K JK; Lee, Julieann C JC; Pekmezci, Melike M; Phillips, Joanna J JJ; Perry, Arie A; Bollen, Andrew W AW; Aghi, Manish K MK; Theodosopoulos, Philip P; Chang, Edward F EF; Hervey-Jumper, Shawn L SL; Berger, Mitchel S MS; Clarke, Jennifer L JL; Chang, Susan M SM; Molinaro, Annette M AM; Solomon, David A DA
Publication Date: 2022-10-03

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 35395677
Variant Present in the following documents:
  • noac089_suppl_supplementary_tables_s1-s11.xlsx, sheet 5
View BVdb publication page



Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: A289V
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
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Case Report: Benefits of a NSCLC Patient With EGFR A289G/F287_G288insHA cis Mutations From Immunotherapy in Combination With Antiangiogenesis and Chemotherapy and Sequential Treatment of EGFR-TKI.

Frontiers In Oncology
Zhang, He H; Dong, Weiwei W; Zhao, Huixia H; Hu, Yanyan Y; You, Xia X; Sun, Tingting T; Xiao, Wenhua W
Publication Date: 2022

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 35251994
Variant Present in the following documents:
  • Main text
  • fonc-12-826938.pdf
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: EGFR: 866C>T; Ala289Val
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data3.xlsx, sheet 1
  • Supplementary_Data2.xlsx, sheet 1
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: EGFR: Ala289Val
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Nature Biotechnology
Sánchez-Rivera, Francisco J FJ; Diaz, Bianca J BJ; Kastenhuber, Edward R ER; Schmidt, Henri H; Katti, Alyna A; Kennedy, Margaret M; Tem, Vincent V; Ho, Yu-Jui YJ; Leibold, Josef J; Paffenholz, Stella V SV; Barriga, Francisco M FM; Chu, Kevan K; Goswami, Sukanya S; Wuest, Alexandra N AN; Simon, Janelle M JM; Tsanov, Kaloyan M KM; Chakravarty, Debyani D; Zhang, Hongxin H; Leslie, Christina S CS; Lowe, Scott W SW; Dow, Lukas E LE
Publication Date: 2022-06

Variant appearance in text: EGFR: A289V
PubMed Link: 35165384
Variant Present in the following documents:
  • NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 4
  • NIHMS1760571-supplement-Supplementary_Table_S7.xlsx, sheet 5
  • NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 6
View BVdb publication page



Establishment and application of a method of next generation sequencing of 285 genes in lung cancer based on Ion-Proton platform.

Translational Cancer Research
Chen, Yu Y; Zhang, Xu-Chao XC; Yan, Wen-Qing WQ; Guo, Wei-Bang WB; Xie, Zhi Z; Lu, Dan-Xia DX; Lv, Zhi-Yi ZY; Chen, Zhi-Hong ZH; Su, Jian J
Publication Date: 2020-07

Variant appearance in text: EGFR: 866C>T; A289V
PubMed Link: 35117791
Variant Present in the following documents:
  • Main text
View BVdb publication page



Precision cancer genome testing needs proficiency testing involving all stakeholders.

Scientific Reports
Maekawa, Masato M; Taniguchi, Terumi T; Nishio, Kazuto K; Sakai, Kazuko K; Matsushita, Kazuyuki K; Nakatani, Kaname K; Ishige, Takayuki T; Ikejiri, Makoto M; Nishihara, Hiroshi H; Sunami, Kuniko K; Yatabe, Yasushi Y; Hatanaka, Kanako C KC; Hatanaka, Yutaka Y; Yamamoto, Yoshihiro Y; Fukuyama, Keita K; Oda, Shinya S; Saito, Kayoko K; Yokomura, Mamoru M; Kubo, Yuji Y; Sato, Hiroko H; Tanaka, Yoshinori Y; Fuchioka, Misa M; Yamasaki, Tadashi T; Matsuda, Koichiro K; Kurachi, Kiyotaka K; Funai, Kazuhiro K; Baba, Satoshi S; Iwaizumi, Moriya M
Publication Date: 2022-01-27

Variant appearance in text: EGFR: 866C>T; Ala289Val; rs149840192
PubMed Link: 35087199
Variant Present in the following documents:
  • 41598_2022_5589_MOESM1_ESM.pdf
View BVdb publication page



Precision cancer genome testing needs proficiency testing involving all stakeholders.

Scientific Reports
Maekawa, Masato M; Taniguchi, Terumi T; Nishio, Kazuto K; Sakai, Kazuko K; Matsushita, Kazuyuki K; Nakatani, Kaname K; Ishige, Takayuki T; Ikejiri, Makoto M; Nishihara, Hiroshi H; Sunami, Kuniko K; Yatabe, Yasushi Y; Hatanaka, Kanako C KC; Hatanaka, Yutaka Y; Yamamoto, Yoshihiro Y; Fukuyama, Keita K; Oda, Shinya S; Saito, Kayoko K; Yokomura, Mamoru M; Kubo, Yuji Y; Sato, Hiroko H; Tanaka, Yoshinori Y; Fuchioka, Misa M; Yamasaki, Tadashi T; Matsuda, Koichiro K; Kurachi, Kiyotaka K; Funai, Kazuhiro K; Baba, Satoshi S; Iwaizumi, Moriya M
Publication Date: 2022-01-27

Variant appearance in text: EGFR: 866C>T; Ala289Val; rs149840192
PubMed Link: 35087199
Variant Present in the following documents:
  • 41598_2022_5589_MOESM1_ESM.pdf
View BVdb publication page



Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas.

Neuro-Oncology Advances
van de Geer, Wesley S WS; Hoogstrate, Youri Y; Draaisma, Kaspar K; Robe, Pierre A PA; Bins, Sander S; Mathijssen, Ron H J RHJ; French, Pim P; van de Werken, Harmen J G HJG; de Vos, Filip Y F FYF
Publication Date: 2022

Variant appearance in text: EGFR: Ala289Val
PubMed Link: 35047820
Variant Present in the following documents:
  • vdab177_suppl_supplementary_data.xlsx, sheet 6
View BVdb publication page



Ultrasensitive analysis of genetic instability related to chemical exposure.

Journal Of Applied Genetics
Domoradzki, Tomasz T; Grochowski, Piotr P; Jaśkiewicz, Anna A; Pająk, Beata B
Publication Date: 2022-05

Variant appearance in text: EGFR: A289V
PubMed Link: 34967917
Variant Present in the following documents:
  • Main text
  • 13353_2021_Article_677.pdf
View BVdb publication page



IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation.

Acta Neuropathologica Communications
Barresi, Valeria V; Simbolo, Michele M; Mafficini, Andrea A; Martini, Maurizio M; Calicchia, Martina M; Piredda, Maria Liliana ML; Ciaparrone, Chiara C; Bonizzato, Giada G; Ammendola, Serena S; Caffo, Maria M; Pinna, Giampietro G; Sala, Francesco F; Lawlor, Rita Teresa RT; Ghimenton, Claudio C; Scarpa, Aldo A
Publication Date: 2021-12-24

Variant appearance in text: EGFR: 866C>T; Ala289Val; rs149840192
PubMed Link: 34952640
Variant Present in the following documents:
  • 40478_2021_1304_MOESM3_ESM.xlsx, sheet 2
View BVdb publication page



IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation.

Acta Neuropathologica Communications
Barresi, Valeria V; Simbolo, Michele M; Mafficini, Andrea A; Martini, Maurizio M; Calicchia, Martina M; Piredda, Maria Liliana ML; Ciaparrone, Chiara C; Bonizzato, Giada G; Ammendola, Serena S; Caffo, Maria M; Pinna, Giampietro G; Sala, Francesco F; Lawlor, Rita Teresa RT; Ghimenton, Claudio C; Scarpa, Aldo A
Publication Date: 2021-12-24

Variant appearance in text: EGFR: 866C>T; Ala289Val; rs149840192
PubMed Link: 34952640
Variant Present in the following documents:
  • 40478_2021_1304_MOESM3_ESM.xlsx, sheet 2
View BVdb publication page



A Summary of the Inaugural WHO Classification of Pediatric Tumors: Transitioning from the Optical into the Molecular Era.

Cancer Discovery
Pfister, Stefan M SM; Reyes-Múgica, Miguel M; Chan, John K C JKC; Hasle, Henrik H; Lazar, Alexander J AJ; Rossi, Sabrina S; Ferrari, Andrea A; Jarzembowski, Jason A JA; Pritchard-Jones, Kathy K; Hill, D Ashley DA; Jacques, Thomas S TS; Wesseling, Pieter P; López Terrada, Dolores H DH; von Deimling, Andreas A; Kratz, Christian P CP; Cree, Ian A IA; Alaggio, Rita R
Publication Date: 2022-02

Variant appearance in text: EGFR: A289V
PubMed Link: 34921008
Variant Present in the following documents:
  • cd-21-1094_supp4.xlsx, sheet 1
View BVdb publication page



Tyrosine Kinase Inhibitors in Adult Glioblastoma: An (Un)Closed Chapter?

Cancers
Aldaz, Paula P; Arozarena, Imanol I
Publication Date: 2021-11-18

Variant appearance in text: EGFR: A289V
PubMed Link: 34830952
Variant Present in the following documents:
  • Main text
  • cancers-13-05799.pdf
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Treatment of MGMT promoter unmethylated glioblastoma with PD-1 inhibitor combined with anti-angiogenesis and epidermal growth factor receptor tyrosine kinase inhibitor: a case report.

Annals Of Translational Medicine
Wang, Zheng Z; Du, Fangfang F; Ren, Yi Y; Jiang, Wei W
Publication Date: 2021-10

Variant appearance in text: EGFR: A289V
PubMed Link: 34805370
Variant Present in the following documents:
  • atm-09-19-1508.pdf
View BVdb publication page