Publications:

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: EGFR: R377S

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

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Aberrant expression of GSTM5 in lung adenocarcinoma is associated with DNA hypermethylation and poor prognosis.

Bmc Cancer

Hao, Xuewei X; Zhang, Jun J; Chen, Guoyou G; Cao, Weiwei W; Chen, Hongyang H; Chen, Shuo S

Publication Date: 2022-06-21

Variant appearance in text: EGFR: R377S

PubMed Link: 35729618

Variant Present in the following documents:

• 12885_2022_9711_MOESM3_ESM.xlsx, sheet 1

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Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion-Positive Lung Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Lin, Jessica J JJ; Choudhury, Noura J NJ; Yoda, Satoshi S; Zhu, Viola W VW; Johnson, Ted W TW; Sakhtemani, Ramin R; Dagogo-Jack, Ibiayi I; Digumarthy, Subba R SR; Lee, Charlotte C; Do, Andrew A; Peterson, Jennifer J; Prutisto-Chang, Kylie K; Malik, Wafa W; Hubbeling, Harper G HG; Langenbucher, Adam A; Schoenfeld, Adam J AJ; Falcon, Christina J CJ; Temel, Jennifer S JS; Sequist, Lecia V LV; Yeap, Beow Y BY; Lennerz, Jochen K JK; Shaw, Alice T AT; Lawrence, Michael S MS; Ou, Sai-Hong Ignatius SI; Hata, Aaron N AN; Drilon, Alexander A; Gainor, Justin F JF

Publication Date: 2021-05-15

Variant appearance in text: EGFR: R377S

PubMed Link: 33685866

Variant Present in the following documents:

• Main text

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: EGFR: R377S

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

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Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Cancer Cell

Hellmann, Matthew D MD; Nathanson, Tavi T; Rizvi, Hira H; Creelan, Benjamin C BC; Sanchez-Vega, Francisco F; Ahuja, Arun A; Ni, Ai A; Novik, Jacki B JB; Mangarin, Levi M B LMB; Abu-Akeel, Mohsen M; Liu, Cailian C; Sauter, Jennifer L JL; Rekhtman, Natasha N; Chang, Eliza E; Callahan, Margaret K MK; Chaft, Jamie E JE; Voss, Martin H MH; Tenet, Megan M; Li, Xue-Mei XM; Covello, Kelly K; Renninger, Andrea A; Vitazka, Patrik P; Geese, William J WJ; Borghaei, Hossein H; Rudin, Charles M CM; Antonia, Scott J SJ; Swanton, Charles C; Hammerbacher, Jeff J; Merghoub, Taha T; McGranahan, Nicholas N; Snyder, Alexandra A; Wolchok, Jedd D JD

Publication Date: 2018-05-14

Variant appearance in text: EGFR: R377S

PubMed Link: 29657128

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

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Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas.

Npj Genomic Medicine

Madubata, Chioma J CJ; Roshan-Ghias, Alireza A; Chu, Timothy T; Resnick, Samuel S; Zhao, Junfei J; Arnes, Luis L; Wang, Jiguang J; Rabadan, Raul R

Publication Date: 2017

Variant appearance in text: EGFR: R377S

PubMed Link: 29263839

Variant Present in the following documents:

• 41525_2017_32_MOESM8_ESM.xlsx, sheet 4

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Prediction of Protein Interactions by Structural Matching: Prediction of PPI Networks and the Effects of Mutations on PPIs that Combines Sequence and Structural Information.

Methods In Molecular Biology (Clifton, N.J.)

Tuncbag, Nurcan N; Keskin, Ozlem O; Nussinov, Ruth R; Gursoy, Attila A

Publication Date: 2017

Variant appearance in text: EGFR: R377S

PubMed Link: 28150242

Variant Present in the following documents:

• Main text

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The RAS-related GTPase RHOB confers resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer via an AKT-dependent mechanism.

Embo Molecular Medicine

Calvayrac, Olivier O; Mazières, Julien J; Figarol, Sarah S; Marty-Detraves, Claire C; Raymond-Letron, Isabelle I; Bousquet, Emilie E; Farella, Magali M; Clermont-Taranchon, Estelle E; Milia, Julie J; Rouquette, Isabelle I; Guibert, Nicolas N; Lusque, Amélie A; Cadranel, Jacques J; Mathiot, Nathalie N; Savina, Ariel A; Pradines, Anne A; Favre, Gilles G

Publication Date: 2017-02

Variant appearance in text: EGFR: R377S

PubMed Link: 28003335

Variant Present in the following documents:

• EMMM-9-238-s007.pdf

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CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network.

Oncotarget

Fertig, Elana J EJ; Ozawa, Hiroyuki H; Thakar, Manjusha M; Howard, Jason D JD; Kagohara, Luciane T LT; Krigsfeld, Gabriel G; Ranaweera, Ruchira S RS; Hughes, Robert M RM; Perez, Jimena J; Jones, Siân S; Favorov, Alexander V AV; Carey, Jacob J; Stein-O'Brien, Genevieve G; Gaykalova, Daria A DA; Ochs, Michael F MF; Chung, Christine H CH

Publication Date: 2016-11-08

Variant appearance in text: EGFR: R377S

PubMed Link: 27650546

Variant Present in the following documents:

• oncotarget-07-73845-s007.xlsx, sheet 1

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: EGFR: R377S

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer.

Plos One

Engin, H Billur HB; Guney, Emre E; Keskin, Ozlem O; Oliva, Baldo B; Gursoy, Attila A

Publication Date: 2013

Variant appearance in text: EGFR: R377S

PubMed Link: 24278371

Variant Present in the following documents:

• Main text
• pone.0081035.pdf

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