Publications:

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: EGFR: Q432H

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 1296A>T; Gln432His

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research

Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H

Publication Date: 2022-01

Variant appearance in text: N/A

PubMed Link: 34963661

Variant Present in the following documents:

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: EGFR: 1296A>T; Q432H

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: EGFR: Q432H

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

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miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma.

Nature Metabolism

Zhang, Wen Cai WC; Wells, Julie M JM; Chow, Kin-Hoe KH; Huang, He H; Yuan, Min M; Saxena, Tanvi T; Melnick, Mary Ann MA; Politi, Katerina K; Asara, John M JM; Costa, Daniel B DB; Bult, Carol J CJ; Slack, Frank J FJ

Publication Date: 2019-04

Variant appearance in text: EGFR: 1296A>T; Q432H

PubMed Link: 31535082

Variant Present in the following documents:

• NIHMS1523414-supplement-Sup_Tables.xlsx, sheet 7

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MHC class II restricted neoantigen peptides predicted by clonal mutation analysis in lung adenocarcinoma patients: implications on prognostic immunological biomarker and vaccine design.

Bmc Genomics

Cai, Weijing W; Zhou, Dapeng D; Wu, Weibo W; Tan, Wen Ling WL; Wang, Jiaqian J; Zhou, Caicun C; Lou, Yanyan Y

Publication Date: 2018-08-03

Variant appearance in text: EGFR: Q432H

PubMed Link: 30075702

Variant Present in the following documents:

• Main text
• 12864_2018_4958_MOESM4_ESM.xlsx, sheet 1
• 12864_2018_Article_4958.pdf
• 12864_2018_4958_MOESM3_ESM.xlsx, sheet 1
• 12864_2018_4958_MOESM5_ESM.xlsx, sheet 1

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Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Cancer Cell

Hellmann, Matthew D MD; Nathanson, Tavi T; Rizvi, Hira H; Creelan, Benjamin C BC; Sanchez-Vega, Francisco F; Ahuja, Arun A; Ni, Ai A; Novik, Jacki B JB; Mangarin, Levi M B LMB; Abu-Akeel, Mohsen M; Liu, Cailian C; Sauter, Jennifer L JL; Rekhtman, Natasha N; Chang, Eliza E; Callahan, Margaret K MK; Chaft, Jamie E JE; Voss, Martin H MH; Tenet, Megan M; Li, Xue-Mei XM; Covello, Kelly K; Renninger, Andrea A; Vitazka, Patrik P; Geese, William J WJ; Borghaei, Hossein H; Rudin, Charles M CM; Antonia, Scott J SJ; Swanton, Charles C; Hammerbacher, Jeff J; Merghoub, Taha T; McGranahan, Nicholas N; Snyder, Alexandra A; Wolchok, Jedd D JD

Publication Date: 2018-05-14

Variant appearance in text: EGFR: Q432H

PubMed Link: 29657128

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

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Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas.

Npj Genomic Medicine

Madubata, Chioma J CJ; Roshan-Ghias, Alireza A; Chu, Timothy T; Resnick, Samuel S; Zhao, Junfei J; Arnes, Luis L; Wang, Jiguang J; Rabadan, Raul R

Publication Date: 2017

Variant appearance in text: EGFR: Q432H

PubMed Link: 29263839

Variant Present in the following documents:

• 41525_2017_32_MOESM8_ESM.xlsx, sheet 4

View BVdb publication page

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Prediction of Protein Interactions by Structural Matching: Prediction of PPI Networks and the Effects of Mutations on PPIs that Combines Sequence and Structural Information.

Methods In Molecular Biology (Clifton, N.J.)

Tuncbag, Nurcan N; Keskin, Ozlem O; Nussinov, Ruth R; Gursoy, Attila A

Publication Date: 2017

Variant appearance in text: EGFR: Q432H

PubMed Link: 28150242

Variant Present in the following documents:

• Main text

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The RAS-related GTPase RHOB confers resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer via an AKT-dependent mechanism.

Embo Molecular Medicine

Calvayrac, Olivier O; Mazières, Julien J; Figarol, Sarah S; Marty-Detraves, Claire C; Raymond-Letron, Isabelle I; Bousquet, Emilie E; Farella, Magali M; Clermont-Taranchon, Estelle E; Milia, Julie J; Rouquette, Isabelle I; Guibert, Nicolas N; Lusque, Amélie A; Cadranel, Jacques J; Mathiot, Nathalie N; Savina, Ariel A; Pradines, Anne A; Favre, Gilles G

Publication Date: 2017-02

Variant appearance in text: EGFR: Q432H

PubMed Link: 28003335

Variant Present in the following documents:

• EMMM-9-238-s001.pdf
• EMMM-9-238-s007.pdf

View BVdb publication page

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VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.

Nucleic Acids Research

Lai, Zhongwu Z; Markovets, Aleksandra A; Ahdesmaki, Miika M; Chapman, Brad B; Hofmann, Oliver O; McEwen, Robert R; Johnson, Justin J; Dougherty, Brian B; Barrett, J Carl JC; Dry, Jonathan R JR

Publication Date: 2016-06-20

Variant appearance in text: EGFR: 1296A>T; Q432H

PubMed Link: 27060149

Variant Present in the following documents:

• supp_gkw227_nar-03544-met-k-2015-File003.xls, sheet 2

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REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer.

Scientific Reports

Zhao, Min M; Rotgans, Bronwyn B; Wang, Tianfang T; Cummins, S F SF

Publication Date: 2016-03-15

Variant appearance in text: N/A

PubMed Link: 26975833

Variant Present in the following documents:

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Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer.

Plos One

Engin, H Billur HB; Guney, Emre E; Keskin, Ozlem O; Oliva, Baldo B; Gursoy, Attila A

Publication Date: 2013

Variant appearance in text: EGFR: Q432H

PubMed Link: 24278371

Variant Present in the following documents:

• Main text
• pone.0081035.pdf

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