Publications:

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Circulating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial.

Nature Medicine

Sartore-Bianchi, Andrea A; Pietrantonio, Filippo F; Lonardi, Sara S; Mussolin, Benedetta B; Rua, Francesco F; Crisafulli, Giovanni G; Bartolini, Alice A; Fenocchio, Elisabetta E; Amatu, Alessio A; Manca, Paolo P; Bergamo, Francesca F; Tosi, Federica F; Mauri, Gianluca G; Ambrosini, Margherita M; Daniel, Francesca F; Torri, Valter V; Vanzulli, Angelo A; Regge, Daniele D; Cappello, Giovanni G; Marchiò, Caterina C; Berrino, Enrico E; Sapino, Anna A; Marsoni, Silvia S; Siena, Salvatore S; Bardelli, Alberto A

Publication Date: 2022-08

Variant appearance in text: EGFR: V441D

PubMed Link: 35915157

Variant Present in the following documents:

• 41591_2022_1886_MOESM1_ESM.pdf

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Structure-guided and phage-assisted evolution of a therapeutic anti-EGFR antibody to reverse acquired resistance.

Nature Communications

Zhuang, Xinlei X; Wang, Zhe Z; Fan, Jiansheng J; Bai, Xuefei X; Xu, Yingchun Y; Chou, James J JJ; Hou, Tingjun T; Chen, Shuqing S; Pan, Liqiang L

Publication Date: 2022-07-30

Variant appearance in text: EGFR: V441D

PubMed Link: 35907884

Variant Present in the following documents:

• Main text
• 41467_2022_32159_MOESM1_ESM.pdf
• 41467_2022_32159_MOESM2_ESM.pdf
• 41467_2022_Article_32159.pdf

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AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery

Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,

Publication Date: 2022-09-02

Variant appearance in text: EGFR: V441D

PubMed Link: 35819403

Variant Present in the following documents:

• cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1

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Next-Generation Sequencing on Circulating Tumor DNA in Advanced Solid Cancer: Swiss Army Knife for the Molecular Tumor Board? A Review of the Literature Focused on FDA Approved Test.

Cells

Vasseur, Damien D; Sassi, Hela H; Bayle, Arnaud A; Tagliamento, Marco M; Besse, Benjamin B; Marzac, Christophe C; Arbab, Ahmadreza A; Auger, Nathalie N; Cotteret, Sophie S; Aldea, Mihaela M; Blanc-Durand, Félix F; Géraud, Arthur A; Gazzah, Anas A; Loriot, Yohann Y; Hollebecque, Antoine A; Martín-Romano, Patricia P; Ngo-Camus, Maud M; Nicotra, Claudio C; Ponce, Santiago S; Sakkal, Madona M; Caron, Olivier O; Smolenschi, Cristina C; Micol, Jean-Baptiste JB; Italiano, Antoine A; Rouleau, Etienne E; Lacroix, Ludovic L

Publication Date: 2022-06-11

Variant appearance in text: EGFR: Val441Asp

PubMed Link: 35741030

Variant Present in the following documents:

• Main text
• cells-11-01901.pdf

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 1322T>A; V441D

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

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Identification of Actionable Fusions as an Anti-EGFR Resistance Mechanism Using a Circulating Tumor DNA Assay.

Jco Precision Oncology

Clifton, Katherine K; Rich, Thereasa A TA; Parseghian, Christine C; Raymond, Victoria M VM; Dasari, Arvind A; Pereira, Allan Andresson Lima AAL; Willis, Jason J; Loree, Jonathan M JM; Bauer, Todd M TM; Chae, Young Kwang YK; Sherrill, Gary G; Fanta, Paul P; Grothey, Axel A; Hendifar, Andrew A; Henry, David D; Mahadevan, Daruka D; Nezami, Mohammad Amin MA; Tan, Benjamin B; Wainberg, Zev A ZA; Lanman, Richard R; Kopetz, Scott S; Morris, Van V

Publication Date: 2019

Variant appearance in text: EGFR: V441D

PubMed Link: 33015522

Variant Present in the following documents:

• PO.19.00141.pdf

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Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

The Journal Of Molecular Diagnostics : Jmd

Clark, Travis A TA; Chung, Jon H JH; Kennedy, Mark M; Hughes, Jason D JD; Chennagiri, Niru N; Lieber, Daniel S DS; Fendler, Bernard B; Young, Lauren L; Zhao, Mandy M; Coyne, Michael M; Breese, Virginia V; Young, Geneva G; Donahue, Amy A; Pavlick, Dean D; Tsiros, Alyssa A; Brennan, Timothy T; Zhong, Shan S; Mughal, Tariq T; Bailey, Mark M; He, Jie J; Roels, Steven S; Frampton, Garrett M GM; Spoerke, Jill M JM; Gendreau, Steven S; Lackner, Mark M; Schleifman, Erica E; Peters, Eric E; Ross, Jeffrey S JS; Ali, Siraj M SM; Miller, Vincent A VA; Gregg, Jeffrey P JP; Stephens, Philip J PJ; Welsh, Allison A; Otto, Geoff A GA; Lipson, Doron D

Publication Date: 2018-09

Variant appearance in text: EGFR: V441D

PubMed Link: 29936259

Variant Present in the following documents:

• mmc12.xlsx, sheet 1

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Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial.

Jama Oncology

Montagut, Clara C; Argilés, Guillem G; Ciardiello, Fortunato F; Poulsen, Thomas T TT; Dienstmann, Rodrigo R; Kragh, Michael M; Kopetz, Scott S; Lindsted, Trine T; Ding, Cliff C; Vidal, Joana J; Clausell-Tormos, Jenifer J; Siravegna, Giulia G; Sánchez-Martín, Francisco J FJ; Koefoed, Klaus K; Pedersen, Mikkel W MW; Grandal, Michael M MM; Dvorkin, Mikhail M; Wyrwicz, Lucjan L; Rovira, Ana A; Cubillo, Antonio A; Salazar, Ramon R; Desseigne, Françoise F; Nadal, Cristina C; Albanell, Joan J; Zagonel, Vittorina V; Siena, Salvatore S; Fumi, Guglielmo G; Rospo, Giuseppe G; Nadler, Paul P; Horak, Ivan D ID; Bardelli, Alberto A; Tabernero, Josep J

Publication Date: 2018-04-12

Variant appearance in text: EGFR: V441D

PubMed Link: 29423521

Variant Present in the following documents:

• Main text

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Hybrid Capture-Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Cancers of the Gastrointestinal Tract or Anus.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Schrock, Alexa B AB; Pavlick, Dean D; Klempner, Samuel J SJ; Chung, Jon H JH; Forcier, Brady B; Welsh, Allison A; Young, Lauren L; Leyland-Jones, Bryan B; Bordoni, Rodolfo R; Carvajal, Richard D RD; Chao, Joseph J; Kurzrock, Razelle R; Sicklick, Jason K JK; Ross, Jeffrey S JS; Stephens, Philip J PJ; Devoe, Craig C; Braiteh, Fadi F; Ali, Siraj M SM; Miller, Vincent A VA

Publication Date: 2018-04-15

Variant appearance in text: EGFR: V441D

PubMed Link: 29363525

Variant Present in the following documents:

• Main text

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Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer.

Cancer Discovery

Strickler, John H JH; Loree, Jonathan M JM; Ahronian, Leanne G LG; Parikh, Aparna R AR; Niedzwiecki, Donna D; Pereira, Allan Andresson Lima AAL; McKinney, Matthew M; Korn, W Michael WM; Atreya, Chloe E CE; Banks, Kimberly C KC; Nagy, Rebecca J RJ; Meric-Bernstam, Funda F; Lanman, Richard B RB; Talasaz, AmirAli A; Tsigelny, Igor F IF; Corcoran, Ryan B RB; Kopetz, Scott S

Publication Date: 2018-02

Variant appearance in text: EGFR: V441D

PubMed Link: 29196463

Variant Present in the following documents:

• Main text

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