EGFR c.1322T>G ;(p.V441G)

Variant ID: 7-55227855-T-G

NM_005228.3(EGFR):c.1322T>G;(p.V441G)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


Metastatic colorectal cancer treatment response evaluation by ultra-deep sequencing of cell-free DNA and matched white blood cells.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
van 't Erve, Iris I; Medina, Jamie E JE; Leal, Alessandro A; Papp, Eniko E; Phallen, Jillian J; Adleff, Vilmos V; Chiao, Elaine Jiayuee EJ; Arun, Adith S AS; Bolhuis, Karen K; Simmons, John K JK; Karandikar, Aanavi A; Valkenburg, Kenneth C KC; Sausen, Mark M; Angiuoli, Samuel V SV; Scharpf, Robert B RB; Punt, Cornelis J A CJA; Meijer, Gerrit A GA; Velculescu, Victor E VE; Fijneman, Remond J A RJA
Publication Date: 2022-12-19

Variant appearance in text: EGFR: V441G
PubMed Link: 36534496
Variant Present in the following documents:
  • ccr-22-2538_supplementary_figures_s1-s15_suppfs1-fs15.pdf
View BVdb publication page



Circulating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial.

Nature Medicine
Sartore-Bianchi, Andrea A; Pietrantonio, Filippo F; Lonardi, Sara S; Mussolin, Benedetta B; Rua, Francesco F; Crisafulli, Giovanni G; Bartolini, Alice A; Fenocchio, Elisabetta E; Amatu, Alessio A; Manca, Paolo P; Bergamo, Francesca F; Tosi, Federica F; Mauri, Gianluca G; Ambrosini, Margherita M; Daniel, Francesca F; Torri, Valter V; Vanzulli, Angelo A; Regge, Daniele D; Cappello, Giovanni G; Marchiò, Caterina C; Berrino, Enrico E; Sapino, Anna A; Marsoni, Silvia S; Siena, Salvatore S; Bardelli, Alberto A
Publication Date: 2022-08

Variant appearance in text: EGFR: V441G
PubMed Link: 35915157
Variant Present in the following documents:
  • 41591_2022_1886_MOESM1_ESM.pdf
View BVdb publication page



AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Publication Date: 2022-09-02

Variant appearance in text: EGFR: V441G
PubMed Link: 35819403
Variant Present in the following documents:
  • cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1
View BVdb publication page



Next-Generation Sequencing on Circulating Tumor DNA in Advanced Solid Cancer: Swiss Army Knife for the Molecular Tumor Board? A Review of the Literature Focused on FDA Approved Test.

Cells
Vasseur, Damien D; Sassi, Hela H; Bayle, Arnaud A; Tagliamento, Marco M; Besse, Benjamin B; Marzac, Christophe C; Arbab, Ahmadreza A; Auger, Nathalie N; Cotteret, Sophie S; Aldea, Mihaela M; Blanc-Durand, Félix F; Géraud, Arthur A; Gazzah, Anas A; Loriot, Yohann Y; Hollebecque, Antoine A; Martín-Romano, Patricia P; Ngo-Camus, Maud M; Nicotra, Claudio C; Ponce, Santiago S; Sakkal, Madona M; Caron, Olivier O; Smolenschi, Cristina C; Micol, Jean-Baptiste JB; Italiano, Antoine A; Rouleau, Etienne E; Lacroix, Ludovic L
Publication Date: 2022-06-11

Variant appearance in text: EGFR: Val441Gly
PubMed Link: 35741030
Variant Present in the following documents:
  • Main text
  • cells-11-01901.pdf
View BVdb publication page



Liquid Biopsy-based Precision Therapy in Patients with Advanced Solid Tumors: A Real-world Experience from a Community-based Oncology Practice.

The Oncologist
Choucair, Khalil K; Mattar, Bassam Ibrahim BI; Van Truong, Quoc Q; Koeneke, Travis T; Van Truong, Phu P; Dakhil, Christopher C; Cannon, Michael W MW; Page, Seth Joel SJ; Deutsch, Jeremy Michael JM; Carlson, Eric E; Moore, Dennis Frederic DF; Nabbout, Nassim H NH; Kallail, K James KJ; Dakhil, Shaker R SR; Reddy, Pavan S PS
Publication Date: 2022-03-11

Variant appearance in text: EGFR: V441G
PubMed Link: 35274713
Variant Present in the following documents:
View BVdb publication page



The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Lee, Jessica K JK; Hazar-Rethinam, Mehlika M; Decker, Brennan B; Gjoerup, Ole O; Madison, Russell W RW; Lieber, Daniel S DS; Chung, Jon H JH; Schrock, Alexa B AB; Creeden, James J; Venstrom, Jeffrey J; Alexander, Brian B; Oxnard, Geoffrey R GR
Publication Date: 2022-02-15

Variant appearance in text: EGFR: V441G
PubMed Link: 34753780
Variant Present in the following documents:
  • Main text
  • 728.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 1322T>G; V441G
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Comparison of three commercial decision support platforms for matching of next-generation sequencing results with therapies in patients with cancer.

Esmo Open
Perakis, Samantha O SO; Weber, Sabrina S; Zhou, Qing Q; Graf, Ricarda R; Hojas, Sabine S; Riedl, Jakob M JM; Gerger, Armin A; Dandachi, Nadia N; Balic, Marija M; Hoefler, Gerald G; Schuuring, Ed E; Groen, Harry J M HJM; Geigl, Jochen B JB; Heitzer, Ellen E; Speicher, Michael R MR
Publication Date: 2020-09

Variant appearance in text: EGFR: V441G
PubMed Link: 32967919
Variant Present in the following documents:
  • esmoopen-2020-000872supp001.pdf
View BVdb publication page



Phase and context shape the function of composite oncogenic mutations.

Nature
Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS
Publication Date: 2020-06

Variant appearance in text: EGFR: V441G
PubMed Link: 32461694
Variant Present in the following documents:
  • NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2
View BVdb publication page



Pan-cancer whole-genome analyses of metastatic solid tumours.

Nature
Priestley, Peter P; Baber, Jonathan J; Lolkema, Martijn P MP; Steeghs, Neeltje N; de Bruijn, Ewart E; Shale, Charles C; Duyvesteyn, Korneel K; Haidari, Susan S; van Hoeck, Arne A; Onstenk, Wendy W; Roepman, Paul P; Voda, Mircea M; Bloemendal, Haiko J HJ; Tjan-Heijnen, Vivianne C G VCG; van Herpen, Carla M L CML; Labots, Mariette M; Witteveen, Petronella O PO; Smit, Egbert F EF; Sleijfer, Stefan S; Voest, Emile E EE; Cuppen, Edwin E
Publication Date: 2019-11

Variant appearance in text: EGFR: Val441Gly
PubMed Link: 31645765
Variant Present in the following documents:
  • 41586_2019_1689_MOESM14_ESM.xlsx, sheet 1
  • 41586_2019_1689_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial.

Jama Oncology
Montagut, Clara C; Argilés, Guillem G; Ciardiello, Fortunato F; Poulsen, Thomas T TT; Dienstmann, Rodrigo R; Kragh, Michael M; Kopetz, Scott S; Lindsted, Trine T; Ding, Cliff C; Vidal, Joana J; Clausell-Tormos, Jenifer J; Siravegna, Giulia G; Sánchez-Martín, Francisco J FJ; Koefoed, Klaus K; Pedersen, Mikkel W MW; Grandal, Michael M MM; Dvorkin, Mikhail M; Wyrwicz, Lucjan L; Rovira, Ana A; Cubillo, Antonio A; Salazar, Ramon R; Desseigne, Françoise F; Nadal, Cristina C; Albanell, Joan J; Zagonel, Vittorina V; Siena, Salvatore S; Fumi, Guglielmo G; Rospo, Giuseppe G; Nadler, Paul P; Horak, Ivan D ID; Bardelli, Alberto A; Tabernero, Josep J
Publication Date: 2018-04-12

Variant appearance in text: EGFR: V441G
PubMed Link: 29423521
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer.

Cancer Discovery
Strickler, John H JH; Loree, Jonathan M JM; Ahronian, Leanne G LG; Parikh, Aparna R AR; Niedzwiecki, Donna D; Pereira, Allan Andresson Lima AAL; McKinney, Matthew M; Korn, W Michael WM; Atreya, Chloe E CE; Banks, Kimberly C KC; Nagy, Rebecca J RJ; Meric-Bernstam, Funda F; Lanman, Richard B RB; Talasaz, AmirAli A; Tsigelny, Igor F IF; Corcoran, Ryan B RB; Kopetz, Scott S
Publication Date: 2018-02

Variant appearance in text: EGFR: V441G
PubMed Link: 29196463
Variant Present in the following documents:
  • Main text
View BVdb publication page