Publications:

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Clinical sequencing identifies potential actionable alterations in a high rate of urachal and primary bladder adenocarcinomas.

Cancer Medicine

Varadi, Melinda M; Nagy, Nikolett N; Reis, Henning H; Hadaschik, Boris B; Niedworok, Christian C; Modos, Orsolya O; Szendroi, Attila A; Ablat, Jason J; Black, Peter C PC; Keresztes, David D; Csizmarik, Anita A; Olah, Csilla C; Gaisa, Nadine T NT; Kiss, Andras A; Timar, Jozsef J; Toth, Erika E; Csernak, Erzsebet E; Gerstner, Arpad A; Mittal, Vinay V; Karkampouna, Sofia S; Kruithof de Julio, Marianna M; Gyorffy, Balazs B; Bedics, Gabor G; Rink, Michael M; Fisch, Margit M; Nyirady, Peter P; Szarvas, Tibor T

Publication Date: 2023-01-20

Variant appearance in text: EGFR: Gly465Arg

PubMed Link: 36670542

Variant Present in the following documents:

• CAM4-12-9041-s001.xlsx, sheet 1

View BVdb publication page

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Metastatic colorectal cancer treatment response evaluation by ultra-deep sequencing of cell-free DNA and matched white blood cells.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

van 't Erve, Iris I; Medina, Jamie E JE; Leal, Alessandro A; Papp, Eniko E; Phallen, Jillian J; Adleff, Vilmos V; Chiao, Elaine Jiayuee EJ; Arun, Adith S AS; Bolhuis, Karen K; Simmons, John K JK; Karandikar, Aanavi A; Valkenburg, Kenneth C KC; Sausen, Mark M; Angiuoli, Samuel V SV; Scharpf, Robert B RB; Punt, Cornelis J A CJA; Meijer, Gerrit A GA; Velculescu, Victor E VE; Fijneman, Remond J A RJA

Publication Date: 2022-12-19

Variant appearance in text: EGFR: G465R

PubMed Link: 36534496

Variant Present in the following documents:

• ccr-22-2538_supplementary_figures_s1-s15_suppfs1-fs15.pdf

View BVdb publication page

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Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies.

Frontiers In Oncology

Bergado-Báez, Gretchen G; Gonzalez Suarez, Narjara N; García, Lisset Chao LC; Pérez-Martínez, Dayana D; Hernández-Fernández, Diana Rosa DR; Fundora-Barrios, Talia T; Rodríguez-Álvarez, Antonio A; Díaz-Ordaz, Geidy Diana GD; Lindzen, Moshit M; Yarden, Yosef Y; Sánchez-Ramírez, Belinda B

Publication Date: 2022

Variant appearance in text: EGFR: G465R

PubMed Link: 36408164

Variant Present in the following documents:

• fonc-12-951267.pdf

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: EGFR: G465R

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Engaging innate immunity for targeting the epidermal growth factor receptor: Therapeutic options leveraging innate immunity versus adaptive immunity versus inhibition of signaling.

Frontiers In Oncology

Hintzen, Gabriele G; Dulat, Holger J HJ; Rajkovic, Erich E

Publication Date: 2022

Variant appearance in text: EGFR: G465R

PubMed Link: 36185288

Variant Present in the following documents:

• Main text
• fonc-12-892212.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 1393G>A; Gly465Arg

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Structure-guided and phage-assisted evolution of a therapeutic anti-EGFR antibody to reverse acquired resistance.

Nature Communications

Zhuang, Xinlei X; Wang, Zhe Z; Fan, Jiansheng J; Bai, Xuefei X; Xu, Yingchun Y; Chou, James J JJ; Hou, Tingjun T; Chen, Shuqing S; Pan, Liqiang L

Publication Date: 2022-07-30

Variant appearance in text: EGFR: G465R

PubMed Link: 35907884

Variant Present in the following documents:

• Main text
• 41467_2022_32159_MOESM2_ESM.pdf
• 41467_2022_Article_32159.pdf
• 41467_2022_32159_MOESM10_ESM.xlsx, sheet 4
• 41467_2022_32159_MOESM1_ESM.pdf

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AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery

Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,

Publication Date: 2022-09-02

Variant appearance in text: EGFR: G465R

PubMed Link: 35819403

Variant Present in the following documents:

• cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1

View BVdb publication page

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Cross-Resistance Among Sequential Cancer Therapeutics: An Emerging Issue.

Frontiers In Oncology

Loria, Rossella R; Vici, Patrizia P; Di Lisa, Francesca Sofia FS; Soddu, Silvia S; Maugeri-Saccà, Marcello M; Bon, Giulia G

Publication Date: 2022

Variant appearance in text: EGFR: G465R

PubMed Link: 35814399

Variant Present in the following documents:

• Main text
• fonc-12-877380.pdf

View BVdb publication page

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Next-Generation Sequencing on Circulating Tumor DNA in Advanced Solid Cancer: Swiss Army Knife for the Molecular Tumor Board? A Review of the Literature Focused on FDA Approved Test.

Cells

Vasseur, Damien D; Sassi, Hela H; Bayle, Arnaud A; Tagliamento, Marco M; Besse, Benjamin B; Marzac, Christophe C; Arbab, Ahmadreza A; Auger, Nathalie N; Cotteret, Sophie S; Aldea, Mihaela M; Blanc-Durand, Félix F; Géraud, Arthur A; Gazzah, Anas A; Loriot, Yohann Y; Hollebecque, Antoine A; Martín-Romano, Patricia P; Ngo-Camus, Maud M; Nicotra, Claudio C; Ponce, Santiago S; Sakkal, Madona M; Caron, Olivier O; Smolenschi, Cristina C; Micol, Jean-Baptiste JB; Italiano, Antoine A; Rouleau, Etienne E; Lacroix, Ludovic L

Publication Date: 2022-06-11

Variant appearance in text: EGFR: Gly465Arg

PubMed Link: 35741030

Variant Present in the following documents:

• Main text
• cells-11-01901.pdf

View BVdb publication page

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EGFR Mutations in Head and Neck Squamous Cell Carcinoma.

International Journal Of Molecular Sciences

Nair, Sindhu S; Bonner, James A JA; Bredel, Markus M

Publication Date: 2022-03-30

Variant appearance in text: EGFR: G465R

PubMed Link: 35409179

Variant Present in the following documents:

• Main text
• ijms-23-03818.pdf

View BVdb publication page

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: EGFR: G465R

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: EGFR: Gly465Arg

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research

Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H

Publication Date: 2022-01

Variant appearance in text: N/A

PubMed Link: 34963661

Variant Present in the following documents:

View BVdb publication page

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: EGFR: 1393G>A; Gly465Arg

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Resistance to anti-EGFR therapies in metastatic colorectal cancer: underlying mechanisms and reversal strategies.

Journal Of Experimental & Clinical Cancer Research : Cr

Zhou, Jing J; Ji, Qing Q; Li, Qi Q

Publication Date: 2021-10-18

Variant appearance in text: EGFR: G465R

PubMed Link: 34663410

Variant Present in the following documents:

• Main text
• 13046_2021_Article_2130.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: G465R

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Pharmacogenomics in colorectal cancer: current role in clinical practice and future perspectives.

Journal Of Cancer Metastasis And Treatment

Battaglin, Francesca F; Puccini, Alberto A; Naseem, Madiha M; Schirripa, Marta M; Berger, Martin D MD; Tokunaga, Ryuma R; McSkane, Michelle M; Khoukaz, Taline T; Soni, Shivani S; Zhang, Wu W; Lenz, Heinz-Josef HJ

Publication Date: 2018

Variant appearance in text: EGFR: G465R

PubMed Link: 34532592

Variant Present in the following documents:

• Main text

View BVdb publication page

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A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models.

Signal Transduction And Targeted Therapy

Fan, Jiansheng J; Zhuang, Xinlei X; Yang, Xiaoyue X; Xu, Yingchun Y; Zhou, Zhan Z; Pan, Liqiang L; Chen, Shuqing S

Publication Date: 2021-09-03

Variant appearance in text: EGFR: G465R

PubMed Link: 34475375

Variant Present in the following documents:

• Main text
• 41392_2021_Article_666.pdf

View BVdb publication page

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A multivalent biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models.

Signal Transduction And Targeted Therapy

Fan, Jiansheng J; Zhuang, Xinlei X; Yang, Xiaoyue X; Xu, Yingchun Y; Zhou, Zhan Z; Pan, Liqiang L; Chen, Shuqing S

Publication Date: 2021-09-03

Variant appearance in text: EGFR: G465R

PubMed Link: 34475375

Variant Present in the following documents:

• Main text
• 41392_2021_Article_666.pdf

View BVdb publication page

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Evaluation of the Idylla ctEGFR mutation assay to detect EGFR mutations in plasma from patients with non-small cell lung cancers.

Scientific Reports

Gilson, Pauline P; Saurel, Chloé C; Salleron, Julia J; Husson, Marie M; Demange, Jessica J; Merlin, Jean-Louis JL; Harlé, Alexandre A

Publication Date: 2021-05-18

Variant appearance in text: EGFR: 1393G>A; G465R

PubMed Link: 34006948

Variant Present in the following documents:

• 41598_2021_90091_MOESM2_ESM.pdf

View BVdb publication page

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Precision Medicine Approaches to Overcome Resistance to Therapy in Head and Neck Cancers.

Frontiers In Oncology

Ortiz-Cuaran, Sandra S; Bouaoud, Jebrane J; Karabajakian, Andy A; Fayette, Jérôme J; Saintigny, Pierre P

Publication Date: 2021

Variant appearance in text: EGFR: G465R

PubMed Link: 33718169

Variant Present in the following documents:

• Main text

View BVdb publication page

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Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope.

Scientific Reports

Makabe, Koki K; Yokoyama, Takeshi T; Uehara, Shiro S; Uchikubo-Kamo, Tomomi T; Shirouzu, Mikako M; Kimura, Kouki K; Tsumoto, Kouhei K; Asano, Ryutaro R; Tanaka, Yoshikazu Y; Kumagai, Izumi I

Publication Date: 2021-03-11

Variant appearance in text: EGFR: G465R

PubMed Link: 33707468

Variant Present in the following documents:

• Main text
• 41598_2021_Article_84171.pdf

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 1393G>A; G465R

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Tyrosine Kinase Receptors in Oncology.

International Journal Of Molecular Sciences

Esteban-Villarrubia, Jorge J; Soto-Castillo, Juan José JJ; Pozas, Javier J; San Román-Gil, María M; Orejana-Martín, Inmaculada I; Torres-Jiménez, Javier J; Carrato, Alfredo A; Alonso-Gordoa, Teresa T; Molina-Cerrillo, Javier J

Publication Date: 2020-11-12

Variant appearance in text: EGFR: G465R

PubMed Link: 33198314

Variant Present in the following documents:

• Main text
• ijms-21-08529.pdf

View BVdb publication page

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Frequency of S492R mutations in the epidermal growth factor receptor: analysis of plasma DNA from patients with metastatic colorectal cancer treated with panitumumab or cetuximab monotherapy.

Cancer Biology & Therapy

Price, Timothy T; Ang, Agnes A; Boedigheimer, Michael M; Kim, Tae Won TW; Li, Jin J; Cascinu, Stefano S; Ruff, Paul P; Satya Suresh, Attili A; Thomas, Anne A; Tjulandin, Sergei S; Peeters, Marc M

Publication Date: 2020-10-02

Variant appearance in text: EGFR: G465R

PubMed Link: 33026965

Variant Present in the following documents:

• Main text
• KCBT_21_1798695.pdf

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: EGFR: G465R

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: EGFR: G465R

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

View BVdb publication page

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An EGFR signature predicts cell line and patient sensitivity to multiple tyrosine kinase inhibitors.

International Journal Of Cancer

Cheng, Chao C; Zhao, Yanding Y; Schaafsma, Evelien E; Weng, Yi-Lan YL; Amos, Christopher C

Publication Date: 2020-11-01

Variant appearance in text: EGFR: G465R

PubMed Link: 32406930

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: G465R

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11

View BVdb publication page

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Refining Cancer Management Using Integrated Liquid Biopsy.

Theranostics

Qiu, Juhui J; Xu, Jianxiong J; Zhang, Kang K; Gu, Wei W; Nie, Liming L; Wang, Guixue G; Luo, Yang Y

Publication Date: 2020

Variant appearance in text: EGFR: G465R

PubMed Link: 32089746

Variant Present in the following documents:

• Main text

View BVdb publication page

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Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer.

Plos One

Nair, Sindhu S; Trummell, Hoa Q HQ; Rajbhandari, Rajani R; Thudi, Nanda K NK; Nozell, Susan E SE; Warram, Jason M JM; Willey, Christopher D CD; Yang, Eddy S ES; Placzek, William J WJ; Bonner, James A JA; Bredel, Markus M

Publication Date: 2020

Variant appearance in text: EGFR: G465R

PubMed Link: 32069320

Variant Present in the following documents:

• Main text

View BVdb publication page

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Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling.

Frontiers In Oncology

Tintelnot, Joseph J; Metz, Sina S; Trentmann, Marie M; Oberle, Anna A; von Wenserski, Lisa L; Schultheiß, Christoph C; Braig, Friederike F; Kriegs, Malte M; Fehse, Boris B; Riecken, Kristoffer K; Bokemeyer, Carsten C; Stein, Alexander A; Binder, Mascha M

Publication Date: 2019

Variant appearance in text: EGFR: G465R

PubMed Link: 32039027

Variant Present in the following documents:

• Main text
• fonc-09-01559.pdf

View BVdb publication page

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Distinguishing Features of Cetuximab and Panitumumab in Colorectal Cancer and Other Solid Tumors.

Frontiers In Oncology

García-Foncillas, Jesús J; Sunakawa, Yu Y; Aderka, Dan D; Wainberg, Zev Z; Ronga, Philippe P; Witzler, Pauline P; Stintzing, Sebastian S

Publication Date: 2019

Variant appearance in text: EGFR: G465R

PubMed Link: 31616627

Variant Present in the following documents:

• Main text

View BVdb publication page

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miR-147b-mediated TCA cycle dysfunction and pseudohypoxia initiate drug tolerance to EGFR inhibitors in lung adenocarcinoma.

Nature Metabolism

Zhang, Wen Cai WC; Wells, Julie M JM; Chow, Kin-Hoe KH; Huang, He H; Yuan, Min M; Saxena, Tanvi T; Melnick, Mary Ann MA; Politi, Katerina K; Asara, John M JM; Costa, Daniel B DB; Bult, Carol J CJ; Slack, Frank J FJ

Publication Date: 2019-04

Variant appearance in text: EGFR: 1393G>A; G465R

PubMed Link: 31535082

Variant Present in the following documents:

• NIHMS1523414-supplement-Sup_Tables.xlsx, sheet 7

View BVdb publication page

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Effects of culture method on response to EGFR therapy in head and neck squamous cell carcinoma cells.

Scientific Reports

Ayuso, Jose M JM; Vitek, Ross R; Swick, Adam D AD; Skala, Melissa C MC; Wisinski, Kari B KB; Kimple, Randall J RJ; Lambert, Paul F PF; Beebe, David J DJ

Publication Date: 2019-08-28

Variant appearance in text: EGFR: G465R

PubMed Link: 31462653

Variant Present in the following documents:

• Main text
• 41598_2019_Article_48764.pdf

View BVdb publication page

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Immune Resistance and EGFR Antagonists in Colorectal Cancer.

Cancers

Giordano, Guido G; Remo, Andrea A; Porras, Almudena A; Pancione, Massimo M

Publication Date: 2019-07-31

Variant appearance in text: EGFR: G465R

PubMed Link: 31370270

Variant Present in the following documents:

• Main text
• cancers-11-01089.pdf

View BVdb publication page

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RAS and BRAF mutations in cell-free DNA are predictive for outcome of cetuximab monotherapy in patients with tissue-tested RAS wild-type advanced colorectal cancer.

Molecular Oncology

van Helden, Erik J EJ; Angus, Lindsay L; Menke-van der Houven van Oordt, C Willemien CW; Heideman, Daniëlle A M DAM; Boon, Eline E; van Es, Suzanne C SC; Radema, Sandra A SA; van Herpen, Carla M L CML; de Groot, Derk Jan A DJA; de Vries, Elisabeth G E EGE; Jansen, Maurice P H M MPHM; Sleijfer, Stefan S; Verheul, Henk M W HMW

Publication Date: 2019-11

Variant appearance in text: EGFR: G465R

PubMed Link: 31350822

Variant Present in the following documents:

• MOL2-13-2361-s007.xlsx, sheet 1

View BVdb publication page

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Detection of ERBB2 (HER2) Gene Amplification Events in Cell-Free DNA and Response to Anti-HER2 Agents in a Large Asian Cancer Patient Cohort.

Frontiers In Oncology

Lee, Jeeyun J; Franovic, Aleksandra A; Shiotsu, Yukimasa Y; Kim, Seung Tae ST; Kim, Kyoung-Mee KM; Banks, Kimberly C KC; Raymond, Victoria M VM; Lanman, Richard B RB

Publication Date: 2019

Variant appearance in text: EGFR: G465R

PubMed Link: 31019892

Variant Present in the following documents:

• Main text
• fonc-09-00212.pdf

View BVdb publication page

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Impact of genomic heterogeneity associated with acquired anti-EGFR resistance in colorectal cancers.

Translational Cancer Research

Chen, Guoli G; Lin, Ming-Tseh MT

Publication Date: 2016-06

Variant appearance in text: EGFR: G465R

PubMed Link: 30713831

Variant Present in the following documents:

• Main text

View BVdb publication page

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Cell-Free DNA Profiling to Discover Mechanisms of Exceptional Response to Cabozantinib Plus Panitumumab in a Patient With Treatment Refractory Metastatic Colorectal Cancer.

Frontiers In Oncology

Jia, Jingquan J; Morse, Michael A MA; Nagy, Rebecca J RJ; Lanman, Richard B RB; Strickler, John H JH

Publication Date: 2018

Variant appearance in text: EGFR: G465R

PubMed Link: 30211110

Variant Present in the following documents:

• Main text

View BVdb publication page

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Combining Mutational Signatures, Clonal Fitness, and Drug Affinity to Define Drug-Specific Resistance Mutations in Cancer.

Cell Chemical Biology

Kaserer, Teresa T; Blagg, Julian J

Publication Date: 2018-11-15

Variant appearance in text: EGFR: G465R

PubMed Link: 30146241

Variant Present in the following documents:

• Main text
• mmc9.pdf
• main.pdf

View BVdb publication page

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Integrative omics analyses broaden treatment targets in human cancer.

Genome Medicine

Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L

Publication Date: 2018-07-27

Variant appearance in text: EGFR: G465R

PubMed Link: 30053901

Variant Present in the following documents:

• 13073_2018_564_MOESM2_ESM.xlsx, sheet 3

View BVdb publication page

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Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

The Journal Of Molecular Diagnostics : Jmd

Clark, Travis A TA; Chung, Jon H JH; Kennedy, Mark M; Hughes, Jason D JD; Chennagiri, Niru N; Lieber, Daniel S DS; Fendler, Bernard B; Young, Lauren L; Zhao, Mandy M; Coyne, Michael M; Breese, Virginia V; Young, Geneva G; Donahue, Amy A; Pavlick, Dean D; Tsiros, Alyssa A; Brennan, Timothy T; Zhong, Shan S; Mughal, Tariq T; Bailey, Mark M; He, Jie J; Roels, Steven S; Frampton, Garrett M GM; Spoerke, Jill M JM; Gendreau, Steven S; Lackner, Mark M; Schleifman, Erica E; Peters, Eric E; Ross, Jeffrey S JS; Ali, Siraj M SM; Miller, Vincent A VA; Gregg, Jeffrey P JP; Stephens, Philip J PJ; Welsh, Allison A; Otto, Geoff A GA; Lipson, Doron D

Publication Date: 2018-09

Variant appearance in text: EGFR: G465R

PubMed Link: 29936259

Variant Present in the following documents:

• mmc12.xlsx, sheet 1

View BVdb publication page

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Update on the types and usage of liquid biopsies in the clinical setting: a systematic review.

Bmc Cancer

Arneth, Borros B

Publication Date: 2018-05-04

Variant appearance in text: EGFR: G465R

PubMed Link: 29728089

Variant Present in the following documents:

• Main text
• 12885_2018_Article_4433.pdf

View BVdb publication page

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Clinical Utility of Analyzing Circulating Tumor DNA in Patients with Metastatic Colorectal Cancer.

The Oncologist

Nakamura, Yoshiaki Y; Yoshino, Takayuki T

Publication Date: 2018-11

Variant appearance in text: EGFR: G465R

PubMed Link: 29700206

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.

Cancer Cell

Hellmann, Matthew D MD; Nathanson, Tavi T; Rizvi, Hira H; Creelan, Benjamin C BC; Sanchez-Vega, Francisco F; Ahuja, Arun A; Ni, Ai A; Novik, Jacki B JB; Mangarin, Levi M B LMB; Abu-Akeel, Mohsen M; Liu, Cailian C; Sauter, Jennifer L JL; Rekhtman, Natasha N; Chang, Eliza E; Callahan, Margaret K MK; Chaft, Jamie E JE; Voss, Martin H MH; Tenet, Megan M; Li, Xue-Mei XM; Covello, Kelly K; Renninger, Andrea A; Vitazka, Patrik P; Geese, William J WJ; Borghaei, Hossein H; Rudin, Charles M CM; Antonia, Scott J SJ; Swanton, Charles C; Hammerbacher, Jeff J; Merghoub, Taha T; McGranahan, Nicholas N; Snyder, Alexandra A; Wolchok, Jedd D JD

Publication Date: 2018-05-14

Variant appearance in text: EGFR: G465R

PubMed Link: 29657128

Variant Present in the following documents:

• mmc3.xlsx, sheet 3

View BVdb publication page

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