EGFR c.1421C>T ;(p.T474I)

Variant ID: 7-55227954-C-T

NM_005228.3(EGFR):c.1421C>T;(p.T474I)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective.

International Journal Of Molecular Sciences
Brullo, Chiara C; Villa, Carla C; Tasso, Bruno B; Russo, Eleonora E; Spallarossa, Andrea A
Publication Date: 2021-07-16

Variant appearance in text: EGFR: T474I
PubMed Link: 34299259
Variant Present in the following documents:
  • Main text
View BVdb publication page



IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study.

Plos Medicine
Li, Yunlei Y; Buijs-Gladdines, Jessica G C A M JG; Canté-Barrett, Kirsten K; Stubbs, Andrew P AP; Vroegindeweij, Eric M EM; Smits, Willem K WK; van Marion, Ronald R; Dinjens, Winand N M WN; Horstmann, Martin M; Kuiper, Roland P RP; Buijsman, Rogier C RC; Zaman, Guido J R GJ; van der Spek, Peter J PJ; Pieters, Rob R; Meijerink, Jules P P JP
Publication Date: 2016-12

Variant appearance in text: EGFR: T474I
PubMed Link: 27997540
Variant Present in the following documents:
  • pmed.1002200.s012.xlsx, sheet 3
View BVdb publication page



Anchor-based classification and type-C inhibitors for tyrosine kinases.

Scientific Reports
Hsu, Kai-Cheng KC; Sung, Tzu-Ying TY; Lin, Chih-Ta CT; Chiu, Yi-Yuan YY; Hsu, John T-A JT; Hung, Hui-Chen HC; Sun, Chung-Ming CM; Barve, Indrajeet I; Chen, Wen-Liang WL; Huang, Wen-Chien WC; Huang, Chin-Ting CT; Chen, Chun-Hwa CH; Yang, Jinn-Moon JM
Publication Date: 2015-06-16

Variant appearance in text: EGFR: T474I
PubMed Link: 26077136
Variant Present in the following documents:
  • Main text
  • srep10938.pdf
View BVdb publication page



Controlling the activity of the Tec kinase Itk by mutation of the phenylalanine gatekeeper residue.

Biochemistry
Joseph, Raji E RE; Andreotti, Amy H AH
Publication Date: 2011-01-18

Variant appearance in text: EGFR: T474I
PubMed Link: 21138328
Variant Present in the following documents:
  • Main text
View BVdb publication page