Publications:

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: EGFR: C628F

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Distribution and favorable prognostic implication of genomic EGFR alterations in IDH-wildtype glioblastoma.

Cancer Medicine

Higa, Nayuta N; Akahane, Toshiaki T; Hamada, Taiji T; Yonezawa, Hajime H; Uchida, Hiroyuki H; Makino, Ryutaro R; Watanabe, Shoji S; Takajo, Tomoko T; Yokoyama, Seiya S; Kirishima, Mari M; Matsuo, Kei K; Fujio, Shingo S; Hanaya, Ryosuke R; Tanimoto, Akihide A; Yoshimoto, Koji K

Publication Date: 2022-06-13

Variant appearance in text: EGFR: C628F

PubMed Link: 35695190

Variant Present in the following documents:

• Main text
• CAM4-12-49.pdf

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Radiotherapy-drug combinations in the treatment of glioblastoma: a brief review.

Cns Oncology

McAleavey, Patrick G PG; Walls, Gerard M GM; Chalmers, Anthony J AJ

Publication Date: 2022-06-01

Variant appearance in text: EGFR: C628F

PubMed Link: 35603818

Variant Present in the following documents:

• Main text
• cns-11-86.pdf

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: C628F

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

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Treatment of MGMT promoter unmethylated glioblastoma with PD-1 inhibitor combined with anti-angiogenesis and epidermal growth factor receptor tyrosine kinase inhibitor: a case report.

Annals Of Translational Medicine

Wang, Zheng Z; Du, Fangfang F; Ren, Yi Y; Jiang, Wei W

Publication Date: 2021-10

Variant appearance in text: EGFR: C628F

PubMed Link: 34805370

Variant Present in the following documents:

• Main text
• atm-09-19-1508.pdf

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Mechanisms of EGFR Resistance in Glioblastoma.

International Journal Of Molecular Sciences

Pan, Peter C PC; Magge, Rajiv S RS

Publication Date: 2020-11-11

Variant appearance in text: EGFR: C628F

PubMed Link: 33187135

Variant Present in the following documents:

• Main text
• ijms-21-08471.pdf

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: EGFR: C628F

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

View BVdb publication page

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: EGFR: C628F

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

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Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFR-mutant glioblastoma.

Cns Oncology

Makhlin, Igor I; Salinas, Ryan D RD; Zhang, Daniel D; Jacob, Fadi F; Ming, Gou-Li GL; Song, Hongjun H; Saxena, Deeksha D; Dorsey, Jay F JF; Nasrallah, MacLean P MP; Morrissette, Jennifer Jd JJ; Binder, Zev A ZA; O'Rourke, Donald M DM; Desai, Arati S AS; Brem, Steven S; Bagley, Stephen J SJ

Publication Date: 2019-11-01

Variant appearance in text: EGFR: C628F

PubMed Link: 31769726

Variant Present in the following documents:

• Main text
• cns-08-43.pdf

View BVdb publication page

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Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports

Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS

Publication Date: 2018-04-03

Variant appearance in text: EGFR: 1883G>T

PubMed Link: 29617658

Variant Present in the following documents:

• NIHMS958974-supplement-5.xlsx, sheet 1
• NIHMS958974-supplement-6.xlsx, sheet 1

View BVdb publication page

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REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer.

Scientific Reports

Zhao, Min M; Rotgans, Bronwyn B; Wang, Tianfang T; Cummins, S F SF

Publication Date: 2016-03-15

Variant appearance in text: EGFR: C628F

PubMed Link: 26975833

Variant Present in the following documents:

• srep23167-s9.xls, sheet 1

View BVdb publication page

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: EGFR: C628F

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nature Medicine

Xie, Mingchao M; Lu, Charles C; Wang, Jiayin J; McLellan, Michael D MD; Johnson, Kimberly J KJ; Wendl, Michael C MC; McMichael, Joshua F JF; Schmidt, Heather K HK; Yellapantula, Venkata V; Miller, Christopher A CA; Ozenberger, Bradley A BA; Welch, John S JS; Link, Daniel C DC; Walter, Matthew J MJ; Mardis, Elaine R ER; Dipersio, John F JF; Chen, Feng F; Wilson, Richard K RK; Ley, Timothy J TJ; Ding, Li L

Publication Date: 2014-12

Variant appearance in text: EGFR: C628F

PubMed Link: 25326804

Variant Present in the following documents:

• NIHMS630249-supplement-5.xlsx, sheet 1

View BVdb publication page

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The integrated landscape of driver genomic alterations in glioblastoma.

Nature Genetics

Frattini, Veronique V; Trifonov, Vladimir V; Chan, Joseph Minhow JM; Castano, Angelica A; Lia, Marie M; Abate, Francesco F; Keir, Stephen T ST; Ji, Alan X AX; Zoppoli, Pietro P; Niola, Francesco F; Danussi, Carla C; Dolgalev, Igor I; Porrati, Paola P; Pellegatta, Serena S; Heguy, Adriana A; Gupta, Gaurav G; Pisapia, David J DJ; Canoll, Peter P; Bruce, Jeffrey N JN; McLendon, Roger E RE; Yan, Hai H; Aldape, Ken K; Finocchiaro, Gaetano G; Mikkelsen, Tom T; Privé, Gilbert G GG; Bigner, Darell D DD; Lasorella, Anna A; Rabadan, Raul R; Iavarone, Antonio A

Publication Date: 2013-10

Variant appearance in text: EGFR: C628F

PubMed Link: 23917401

Variant Present in the following documents:

• NIHMS510851-supplement-3.xlsx, sheet 1

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