Publications:

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P16 immunohistochemistry is a sensitive and specific surrogate marker for CDKN2A homozygous deletion in gliomas.

Acta Neuropathologica Communications

Vij, Meenakshi M; Cho, Benjamin B BB; Yokoda, Raquel T RT; Rashidipour, Omid O; Umphlett, Melissa M; Richardson, Timothy E TE; Tsankova, Nadejda M NM

Publication Date: 2023-05-03

Variant appearance in text: EGFR: S645C

PubMed Link: 37138345

Variant Present in the following documents:

• 40478_2023_1573_MOESM1_ESM.xlsx, sheet 1

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Impact of EGFRA289T/V mutation on relapse pattern in glioblastoma.

Esmo Open

Noeuveglise, A A; Sarafan-Vasseur, N N; Beaussire, L L; Marguet, F F; Modzelewski, R R; Hanzen, C C; Alexandru, C C; Magne, N N; Langlois, O O; Di Fiore, F F; Clatot, F F; Thureau, S S; Fontanilles, M M

Publication Date: 2022-12-22

Variant appearance in text: EGFR: S645C

PubMed Link: 36566697

Variant Present in the following documents:

• main.pdf

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: EGFR: S645C

PubMed Link: 36561320

Variant Present in the following documents:

• Table3.xlsx, sheet 1
• Table2.xlsx, sheet 4

View BVdb publication page

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Oncogenic KRAS alters splicing factor phosphorylation and alternative splicing in lung cancer.

Bmc Cancer

Lo, April A; McSharry, Maria M; Berger, Alice H AH

Publication Date: 2022-12-16

Variant appearance in text: EGFR: S645C

PubMed Link: 36522653

Variant Present in the following documents:

• Main text
• 12885_2022_Article_10311.pdf
• 12885_2022_10311_MOESM5_ESM.pdf

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: EGFR: S645C

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: EGFR: S645C

PubMed Link: 36222846

Variant Present in the following documents:

• ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1
• ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1

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Identification of potential targets of the curcumin analog CCA-1.1 for glioblastoma treatment : integrated computational analysis and in vitro study.

Scientific Reports

Hermawan, Adam A; Wulandari, Febri F; Hanif, Naufa N; Utomo, Rohmad Yudi RY; Jenie, Riris Istighfari RI; Ikawati, Muthi M; Tafrihani, Ahmad Syauqy AS

Publication Date: 2022-08-17

Variant appearance in text: EGFR: 1934C>G; S645C

PubMed Link: 35977996

Variant Present in the following documents:

• 41598_2022_18348_MOESM3_ESM.xlsx, sheet 6

View BVdb publication page

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S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma.

Frontiers In Oncology

Huang, Wenda W; Zou, Ling L; Hao, Zhaonian Z; Wang, Baofeng B; Mao, Feng F; Duan, Qiuhong Q; Guo, Dongsheng D

Publication Date: 2022

Variant appearance in text: EGFR: 1934C>G; S645C

PubMed Link: 35814475

Variant Present in the following documents:

• Main text
• fonc-12-904383.pdf

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: S645C

PubMed Link: 35304574

Variant Present in the following documents:

• Main text
• 41388_2022_Article_2263.pdf

View BVdb publication page

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Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas.

Neuro-Oncology Advances

van de Geer, Wesley S WS; Hoogstrate, Youri Y; Draaisma, Kaspar K; Robe, Pierre A PA; Bins, Sander S; Mathijssen, Ron H J RHJ; French, Pim P; van de Werken, Harmen J G HJG; de Vos, Filip Y F FYF

Publication Date: 2022

Variant appearance in text: EGFR: Ser645Cys

PubMed Link: 35047820

Variant Present in the following documents:

• vdab177_suppl_supplementary_data.xlsx, sheet 6

View BVdb publication page

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A Large Real-World Study on the Effectiveness of the Combined Inhibition of EGFR and MET in EGFR-Mutant Non-Small-Cell Lung Cancer After Development of EGFR-TKI Resistance.

Frontiers In Oncology

Liu, Li L; Qu, Jingjing J; Heng, Jianfu J; Zhou, Chunhua C; Xiong, Yi Y; Yang, Haiyan H; Jiang, Wenjuan W; Zeng, Liang L; Zhu, Songlin S; Zhang, Yongchang Y; Tan, Jiarong J; Hu, Chengping C; Deng, Pengbo P; Yang, Nong N

Publication Date: 2021

Variant appearance in text: EGFR: S645C

PubMed Link: 34660287

Variant Present in the following documents:

• Main text
• fonc-11-722039.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: S645C

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Frontiers In Immunology

Punta, Marco M; Jennings, Victoria A VA; Melcher, Alan A AA; Lise, Stefano S

Publication Date: 2020

Variant appearance in text: EGFR: S645C

PubMed Link: 33133066

Variant Present in the following documents:

• Table_6.xlsx, sheet 7
• Table_1.xlsx, sheet 2
• Table_6.xlsx, sheet 2

View BVdb publication page

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Analysis of genomic and transcriptomic variations as prognostic signature for lung adenocarcinoma.

Bmc Bioinformatics

Zengin, Talip T; Önal-Süzek, Tuğba T

Publication Date: 2020-09-30

Variant appearance in text: EGFR: S645C

PubMed Link: 32998690

Variant Present in the following documents:

• Main text
• 12859_2020_Article_3691.pdf

View BVdb publication page

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: EGFR: S645C

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

View BVdb publication page

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: EGFR: S645C

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: S645C

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: EGFR: S645C

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM13_ESM.xlsx, sheet 1

View BVdb publication page

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Identification of 12 cancer types through genome deep learning.

Scientific Reports

Sun, Yingshuai Y; Zhu, Sitao S; Ma, Kailong K; Liu, Weiqing W; Yue, Yao Y; Hu, Gang G; Lu, Huifang H; Chen, Wenbin W

Publication Date: 2019-11-21

Variant appearance in text: EGFR: S645C

PubMed Link: 31754222

Variant Present in the following documents:

• 41598_2019_53989_MOESM4_ESM.xlsx, sheet 4

View BVdb publication page

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Pan-cancer whole-genome analyses of metastatic solid tumours.

Nature

Priestley, Peter P; Baber, Jonathan J; Lolkema, Martijn P MP; Steeghs, Neeltje N; de Bruijn, Ewart E; Shale, Charles C; Duyvesteyn, Korneel K; Haidari, Susan S; van Hoeck, Arne A; Onstenk, Wendy W; Roepman, Paul P; Voda, Mircea M; Bloemendal, Haiko J HJ; Tjan-Heijnen, Vivianne C G VCG; van Herpen, Carla M L CML; Labots, Mariette M; Witteveen, Petronella O PO; Smit, Egbert F EF; Sleijfer, Stefan S; Voest, Emile E EE; Cuppen, Edwin E

Publication Date: 2019-11

Variant appearance in text: EGFR: Ser645Cys

PubMed Link: 31645765

Variant Present in the following documents:

• 41586_2019_1689_MOESM10_ESM.xlsx, sheet 1
• 41586_2019_1689_MOESM14_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations.

Journal Of Personalized Medicine

Jiang, Jingrui J; Protopopov, Alexei A; Sun, Ruobai R; Lyle, Stephen S; Russell, Meaghan M

Publication Date: 2018-04-09

Variant appearance in text: EGFR: S645C

PubMed Link: 29642553

Variant Present in the following documents:

• Main text
• jpm-08-00013.pdf

View BVdb publication page

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Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports

Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS

Publication Date: 2018-04-03

Variant appearance in text: EGFR: 1934C>G

PubMed Link: 29617658

Variant Present in the following documents:

• NIHMS958974-supplement-5.xlsx, sheet 1

View BVdb publication page

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Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas.

Npj Genomic Medicine

Madubata, Chioma J CJ; Roshan-Ghias, Alireza A; Chu, Timothy T; Resnick, Samuel S; Zhao, Junfei J; Arnes, Luis L; Wang, Jiguang J; Rabadan, Raul R

Publication Date: 2017

Variant appearance in text: EGFR: S645C; rs772046081

PubMed Link: 29263839

Variant Present in the following documents:

• 41525_2017_32_MOESM8_ESM.xlsx, sheet 2

View BVdb publication page

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In the literature: October 2016.

Esmo Open

Cervantes, Andres A

Publication Date: 2016

Variant appearance in text: EGFR: S645C

PubMed Link: 27900207

Variant Present in the following documents:

• Main text
• esmoopen-2016-000103.pdf

View BVdb publication page

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High-throughput Phenotyping of Lung Cancer Somatic Mutations.

Cancer Cell

Berger, Alice H AH; Brooks, Angela N AN; Wu, Xiaoyun X; Shrestha, Yashaswi Y; Chouinard, Candace C; Piccioni, Federica F; Bagul, Mukta M; Kamburov, Atanas A; Imielinski, Marcin M; Hogstrom, Larson L; Zhu, Cong C; Yang, Xiaoping X; Pantel, Sasha S; Sakai, Ryo R; Watson, Jacqueline J; Kaplan, Nathan N; Campbell, Joshua D JD; Singh, Shantanu S; Root, David E DE; Narayan, Rajiv R; Natoli, Ted T; Lahr, David L DL; Tirosh, Itay I; Tamayo, Pablo P; Getz, Gad G; Wong, Bang B; Doench, John J; Subramanian, Aravind A; Golub, Todd R TR; Meyerson, Matthew M; Boehm, Jesse S JS

Publication Date: 2016-08-08

Variant appearance in text: EGFR: S645C

PubMed Link: 27478040

Variant Present in the following documents:

• Main text

View BVdb publication page

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Clonal evolution of glioblastoma under therapy.

Nature Genetics

Wang, Jiguang J; Cazzato, Emanuela E; Ladewig, Erik E; Frattini, Veronique V; Rosenbloom, Daniel I S DI; Zairis, Sakellarios S; Abate, Francesco F; Liu, Zhaoqi Z; Elliott, Oliver O; Shin, Yong-Jae YJ; Lee, Jin-Ku JK; Lee, In-Hee IH; Park, Woong-Yang WY; Eoli, Marica M; Blumberg, Andrew J AJ; Lasorella, Anna A; Nam, Do-Hyun DH; Finocchiaro, Gaetano G; Iavarone, Antonio A; Rabadan, Raul R

Publication Date: 2016-07

Variant appearance in text: EGFR: S645C

PubMed Link: 27270107

Variant Present in the following documents:

• Main text

View BVdb publication page

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REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer.

Scientific Reports

Zhao, Min M; Rotgans, Bronwyn B; Wang, Tianfang T; Cummins, S F SF

Publication Date: 2016-03-15

Variant appearance in text: EGFR: S645C

PubMed Link: 26975833

Variant Present in the following documents:

• srep23167-s9.xls, sheet 1

View BVdb publication page

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: EGFR: S645C

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nature Medicine

Xie, Mingchao M; Lu, Charles C; Wang, Jiayin J; McLellan, Michael D MD; Johnson, Kimberly J KJ; Wendl, Michael C MC; McMichael, Joshua F JF; Schmidt, Heather K HK; Yellapantula, Venkata V; Miller, Christopher A CA; Ozenberger, Bradley A BA; Welch, John S JS; Link, Daniel C DC; Walter, Matthew J MJ; Mardis, Elaine R ER; Dipersio, John F JF; Chen, Feng F; Wilson, Richard K RK; Ley, Timothy J TJ; Ding, Li L

Publication Date: 2014-12

Variant appearance in text: EGFR: S645C

PubMed Link: 25326804

Variant Present in the following documents:

• NIHMS630249-supplement-5.xlsx, sheet 1

View BVdb publication page

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Exon expression arrays as a tool to identify new cancer genes.

Plos One

Schutte, Mieke M; Elstrodt, Fons F; Bralten, Linda B C LB; Nagel, Jord H A JH; Duijm, Elza E; Hollestelle, Antoinette A; Vuerhard, Maartje J MJ; Wasielewski, Marijke M; Peeters, Justine K JK; van der Spek, Peter P; Sillevis Smitt, Peter A PA; French, Pim J PJ

Publication Date: 2007-08-20

Variant appearance in text: EGFR: S645C

PubMed Link: 18688287

Variant Present in the following documents:

• Main text
• pone.0003007.pdf

View BVdb publication page

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