Publications:

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[Progress in Detection of EGFR Exon 20 Insertion Mutation and Targeted Therapies 
in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Wang, Yulu Y; Chu, Tianqing T

Publication Date: 2023-02-20

Variant appearance in text: EGFR: V689M

PubMed Link: 36872052

Variant Present in the following documents:

• zgfazz-26-135.pdf

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2065G>A; V689M

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 2
• Table_2.xlsx, sheet 3

View BVdb publication page

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Ultrasensitive tumour-agnostic non-invasive detection of colorectal cancer recurrence using ctDNA methylation.

Clinical And Translational Medicine

Xiao, Yu Y; Wang, Xiaodong X; Weng, Hong H; Ding, Zhao Z; Qian, Kaiyu K; Jin, Wan W; Lu, Sen S; Ju, Lingao L; He, Zhiwen Z; Wang, Gang G; Xie, Xiaoyu X; Liu, Dongmei D; Fan, Zhou Z; Wu, Kai K; Li, Sheng S; Guo, Huanhuan H; Qian, Guofeng G; Jiang, Wei W; Leng, Yunji Y; Zhao, Junpeng J; Cao, Xinyue X; Peng, Minsheng M; Jiang, Congqing C; Li, Li L; Zhang, Yi Y; Wang, Xinghuan X

Publication Date: 2022-09

Variant appearance in text: EGFR: 2065G>A; V689M

PubMed Link: 36103400

Variant Present in the following documents:

• CTM2-12-e1015-s002.xlsx, sheet 1

View BVdb publication page

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Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).

Bmc Cancer

Zhang, Bo B; Shi, Chunlei C; Gao, Zhiqiang Z; Zhong, Hua H; Xiong, Liwen L; Gu, Aiqin A; Wang, Weimin W; Chu, Tianqing T; Zhang, Wei W; Wang, Huimin H; Zhang, Xueyan X; Zhong, Runbo R; Han, Baohui B

Publication Date: 2022-03-19

Variant appearance in text: EGFR: V689M

PubMed Link: 35305596

Variant Present in the following documents:

• Main text
• 12885_2022_Article_9409.pdf

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2065G>A; V689M

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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EGFR first- and second-generation TKIs-there is still place for them in EGFR-mutant NSCLC patients.

Translational Cancer Research

Karachaliou, Niki N; Fernandez-Bruno, Manuel M; Bracht, Jillian Wilhelmina Paulina JWP; Rosell, Rafael R

Publication Date: 2019-01

Variant appearance in text: EGFR: V689M

PubMed Link: 35117062

Variant Present in the following documents:

• tcr-08-S1-S23.pdf

View BVdb publication page

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research

Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H

Publication Date: 2022-01

Variant appearance in text: EGFR: V689M

PubMed Link: 34963661

Variant Present in the following documents:

• supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3

View BVdb publication page

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Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study.

Frontiers In Oncology

Lin, Xinqing X; Peng, Muyun M; Chen, Quanfang Q; Yuan, Mingming M; Chen, Rongrong R; Deng, Haiyi H; Deng, Jiaxi J; Liu, Ouqi O; Weng, Yuqing Y; Chen, Mingjiu M; Zhou, Chengzhi C

Publication Date: 2021

Variant appearance in text: EGFR: V689M

PubMed Link: 34869019

Variant Present in the following documents:

• Main text
• fonc-11-774156.pdf

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Val689Met

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Val689Met

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

View BVdb publication page

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Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.

Jama Oncology

Cobain, Erin F EF; Wu, Yi-Mi YM; Vats, Pankaj P; Chugh, Rashmi R; Worden, Francis F; Smith, David C DC; Schuetze, Scott M SM; Zalupski, Mark M MM; Sahai, Vaibhav V; Alva, Ajjai A; Schott, Anne F AF; Caram, Megan E V MEV; Hayes, Daniel F DF; Stoffel, Elena M EM; Jacobs, Michelle F MF; Kumar-Sinha, Chandan C; Cao, Xuhong X; Wang, Rui R; Lucas, David D; Ning, Yu Y; Rabban, Erica E; Bell, Janice J; Camelo-Piragua, Sandra S; Udager, Aaron M AM; Cieslik, Marcin M; Lonigro, Robert J RJ; Kunju, Lakshmi P LP; Robinson, Dan R DR; Talpaz, Moshe M; Chinnaiyan, Arul M AM

Publication Date: 2021-04-01

Variant appearance in text: EGFR: V689M

PubMed Link: 33630025

Variant Present in the following documents:

• jamaoncol-e207987-s004.xlsx, sheet 2

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2065G>A; V689M

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Phase and context shape the function of composite oncogenic mutations.

Nature

Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS

Publication Date: 2020-06

Variant appearance in text: EGFR: V689M

PubMed Link: 32461694

Variant Present in the following documents:

• NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2

View BVdb publication page

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The role of myoglobin in epithelial cancers: Insights from transcriptomics.

International Journal Of Molecular Medicine

Bicker, Anne A; Nauth, Theresa T; Gerst, Daniela D; Aboouf, Mostafa Ahmed MA; Fandrey, Joachim J; Kristiansen, Glen G; Gorr, Thomas Alexander TA; Hankeln, Thomas T

Publication Date: 2020-02

Variant appearance in text: EGFR: 2065G>A

PubMed Link: 31894249

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 11

View BVdb publication page

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[A Review of EGFR-TKIs Therapy of Non-small Cell Lung Cancer
with Uncommon EGFR Mutations].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Du, Wenxing W; Wo, Yang Y; Lu, Tong T; Wang, Yuanyong Y; Jiao, Wenjie W

Publication Date: 2019-09-20

Variant appearance in text: EGFR: V689M

PubMed Link: 31526464

Variant Present in the following documents:

• Main text
• zgfazz-22-9-590.pdf

View BVdb publication page

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Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario.

International Journal Of Molecular Sciences

Russo, Alessandro A; Franchina, Tindara T; Ricciardi, Giuseppina G; Battaglia, Alessandra A; Picciotto, Maria M; Adamo, Vincenzo V

Publication Date: 2019-03-21

Variant appearance in text: EGFR: V689M

PubMed Link: 30901844

Variant Present in the following documents:

• Main text
• ijms-20-01431.pdf

View BVdb publication page

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Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Bmc Cancer

Koyama, Takahiko T; Rhrissorrakrai, Kahn K; Parida, Laxmi L

Publication Date: 2019-02-01

Variant appearance in text: EGFR: 2065G>A; V689M

PubMed Link: 30709382

Variant Present in the following documents:

• 12885_2019_5313_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Fan, Pang-Dian PD; Narzisi, Giuseppe G; Jayaprakash, Anitha D AD; Venturini, Elisa E; Robine, Nicolas N; Smibert, Peter P; Germer, Soren S; Yu, Helena A HA; Jordan, Emmet J EJ; Paik, Paul K PK; Janjigian, Yelena Y YY; Chaft, Jamie E JE; Wang, Lu L; Jungbluth, Achim A AA; Middha, Sumit S; Spraggon, Lee L; Qiao, Huan H; Lovly, Christine M CM; Kris, Mark G MG; Riely, Gregory J GJ; Politi, Katerina K; Varmus, Harold H; Ladanyi, Marc M

Publication Date: 2018-06-26

Variant appearance in text: EGFR: V689M

PubMed Link: 29875142

Variant Present in the following documents:

• Main text
• pnas.201717782.pdf

View BVdb publication page

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: V689M

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 3

View BVdb publication page

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Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Oncology Letters

Quan, Xueping X; Gao, Hongjun H; Wang, Zhikuan Z; Li, Jie J; Zhao, Wentao W; Liang, Wei W; Yu, Qiang Q; Guo, Dongliang D; Hao, Zhanping Z; Liu, Jingxin J

Publication Date: 2018-02

Variant appearance in text: EGFR: V689M

PubMed Link: 29434916

Variant Present in the following documents:

• Main text
• ol-15-02-2131.pdf

View BVdb publication page

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Activation of the EGF Receptor by Ligand Binding and Oncogenic Mutations: The "Rotation Model".

Cells

Purba, Endang R ER; Saita, Ei-Ichiro EI; Maruyama, Ichiro N IN

Publication Date: 2017-06-02

Variant appearance in text: EGFR: V689M

PubMed Link: 28574446

Variant Present in the following documents:

• Main text
• cells-06-00013.pdf

View BVdb publication page

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Clinical characteristics and response to tyrosine kinase inhibitors of patients with non-small cell lung cancer harboring uncommon epidermal growth factor receptor mutations.

Chinese Journal Of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu

Zhang, Yan Y; Wang, Zheng Z; Hao, Xuezhi X; Hu, Xingsheng X; Wang, Hongyu H; Wang, Yan Y; Ying, Jianming J

Publication Date: 2017-02

Variant appearance in text: EGFR: V689M

PubMed Link: 28373750

Variant Present in the following documents:

• Main text
• cjcr-29-1-18.pdf

View BVdb publication page

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ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.

Nature Communications

Williamson, Chris T CT; Miller, Rowan R; Pemberton, Helen N HN; Jones, Samuel E SE; Campbell, James J; Konde, Asha A; Badham, Nicholas N; Rafiq, Rumana R; Brough, Rachel R; Gulati, Aditi A; Ryan, Colm J CJ; Francis, Jeff J; Vermulen, Peter B PB; Reynolds, Andrew R AR; Reaper, Philip M PM; Pollard, John R JR; Ashworth, Alan A; Lord, Christopher J CJ

Publication Date: 2016-12-13

Variant appearance in text: EGFR: V689M

PubMed Link: 27958275

Variant Present in the following documents:

• ncomms13837-s4.xlsx, sheet 1

View BVdb publication page

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Epidermal growth factor receptor in non-small cell lung cancer.

Translational Lung Cancer Research

Prabhakar, Charles N CN

Publication Date: 2015-04

Variant appearance in text: EGFR: V689M

PubMed Link: 25870793

Variant Present in the following documents:

• Main text

View BVdb publication page

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Mechanisms of drug resistance in kinases.

Expert Opinion On Investigational Drugs

Barouch-Bentov, Rina R; Sauer, Karsten K

Publication Date: 2011-02

Variant appearance in text: EGFR: V689M

PubMed Link: 21235428

Variant Present in the following documents:

• Main text

View BVdb publication page

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EGFR-mutated lung cancer: a paradigm of molecular oncology.

Oncotarget

Zhang, Zhenfeng Z; Stiegler, Amy L AL; Boggon, Titus J TJ; Kobayashi, Susumu S; Halmos, Balazs B

Publication Date: 2010-11

Variant appearance in text: EGFR: V689M

PubMed Link: 21165163

Variant Present in the following documents:

• Main text
• oncotarget-01-497.pdf

View BVdb publication page

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