Publications:

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Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need.

International Journal Of Molecular Sciences

Pretelli, Giulia G; Spagnolo, Calogera Claudia CC; Ciappina, Giuliana G; Santarpia, Mariacarmela M; Pasello, Giulia G

Publication Date: 2023-05-17

Variant appearance in text: EGFR: V689L

PubMed Link: 37240224

Variant Present in the following documents:

• Main text
• ijms-24-08878.pdf

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs397517083

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

View BVdb publication page

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Comprehensive analyses of genomic features and mutational signatures in adenosquamous carcinoma of the lung.

Frontiers In Oncology

Wang, Hongbiao H; Liu, Jun J; Zhu, Sujuan S; Miao, Kun K; Li, Zhifeng Z; Qi, Xiaofang X; Huang, Lujia L; Guo, Lijie L; Wang, Yan Y; Cai, Yuyin Y; Lin, Yingcheng Y

Publication Date: 2022

Variant appearance in text: EGFR: V689L

PubMed Link: 36185247

Variant Present in the following documents:

• Main text
• fonc-12-945843.pdf

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AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer.

Cancer Discovery

Noronha, Ashish A; Belugali Nataraj, Nishanth N; Lee, Joo Sang JS; Zhitomirsky, Benny B; Oren, Yaara Y; Oster, Sara S; Lindzen, Moshit M; Mukherjee, Saptaparna S; Will, Rainer R; Ghosh, Soma S; Simoni-Nieves, Arturo A; Verma, Aakanksha A; Chatterjee, Rishita R; Borgoni, Simone S; Robinson, Welles W; Sinha, Sanju S; Brandis, Alexander A; Kerr, D Lucas DL; Wu, Wei W; Sekar, Arunachalam A; Giri, Suvendu S; Chung, Youngmin Y; Drago-Garcia, Diana D; Danysh, Brian P BP; Lauriola, Mattia M; Fiorentino, Michelangelo M; Ardizzoni, Andrea A; Oren, Moshe M; Blakely, Collin M CM; Ezike, Jideofor J; Wiemann, Stefan S; Parida, Laxmi L; Bivona, Trever G TG; Aqeilan, Rami I RI; Brugge, Joan S JS; Regev, Aviv A; Getz, Gad G; Ruppin, Eytan E; Yarden, Yosef Y

Publication Date: 2022-11-02

Variant appearance in text: EGFR: V689L

PubMed Link: 35895872

Variant Present in the following documents:

• Main text
• 2666.pdf

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: EGFR: 2065G>C; Val689Leu

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1
• Supplementary_Data3.xlsx, sheet 1

View BVdb publication page

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RBM10 Deficiency Is Associated With Increased Immune Activity in Lung Adenocarcinoma.

Frontiers In Oncology

Liu, Bing B; Wang, Yaqi Y; Wang, Han H; Li, Zhongwu Z; Yang, Lujing L; Yan, Shi S; Yang, Xin X; Ma, Yuanyuan Y; Gao, Xuan X; Guan, Yanfang Y; Yi, Xin X; Xia, Xuefeng X; Li, Jingjing J; Wu, Nan N

Publication Date: 2021

Variant appearance in text: EGFR: V689L

PubMed Link: 34367963

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Clinical Value of EGFR Copy Number Gain Determined by Amplicon-Based Targeted Next Generation Sequencing in Patients with EGFR-Mutated NSCLC.

Targeted Oncology

Wei, Jiacong J; Meng, Pei P; Terpstra, Miente Martijn MM; van Rijk, Anke A; Tamminga, Menno M; Scherpen, Frank F; Ter Elst, Arja A; Alimohamed, Mohamed Z MZ; Johansson, Lennart F LF; Stigt, Jos J; Gijtenbeek, Rolof P G RPG; van Putten, John J; Hiltermann, T Jeroen N TJN; Groen, Harry J M HJM; Kok, Klaas K; van der Wekken, Anthonie J AJ; van den Berg, Anke A

Publication Date: 2021-03

Variant appearance in text: EGFR: V689L

PubMed Link: 33606136

Variant Present in the following documents:

• 11523_2021_798_MOESM1_ESM.pdf

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The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Therapeutic Advances In Medical Oncology

Wu, Shang-Gin SG; Yu, Chong-Jen CJ; Yang, James Chih-Hsin JC; Shih, Jin-Yuan JY

Publication Date: 2020

Variant appearance in text: EGFR: V689L

PubMed Link: 32843903

Variant Present in the following documents:

• Main text
• 10.1177_1758835920946156.pdf

View BVdb publication page

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Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Bmc Cancer

Koyama, Takahiko T; Rhrissorrakrai, Kahn K; Parida, Laxmi L

Publication Date: 2019-02-01

Variant appearance in text: EGFR: 2065G>C; V689L

PubMed Link: 30709382

Variant Present in the following documents:

• 12885_2019_5313_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Afatinib in the first-line treatment of patients with non-small cell lung cancer: clinical evidence and experience.

Therapeutic Advances In Respiratory Disease

Ricciuti, Biagio B; Baglivo, Sara S; De Giglio, Andrea A; Chiari, Rita R

Publication Date: 2018

Variant appearance in text: EGFR: V689L

PubMed Link: 30355049

Variant Present in the following documents:

• Main text
• 10.1177_1753466618808659.pdf

View BVdb publication page

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: EGFR: V689L; rs397517083

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

View BVdb publication page

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The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.

Genome Medicine

Garofalo, Andrea A; Sholl, Lynette L; Reardon, Brendan B; Taylor-Weiner, Amaro A; Amin-Mansour, Ali A; Miao, Diana D; Liu, David D; Oliver, Nelly N; MacConaill, Laura L; Ducar, Matthew M; Rojas-Rudilla, Vanesa V; Giannakis, Marios M; Ghazani, Arezou A; Gray, Stacy S; Janne, Pasi P; Garber, Judy J; Joffe, Steve S; Lindeman, Neal N; Wagle, Nikhil N; Garraway, Levi A LA; Van Allen, Eliezer M EM

Publication Date: 2016-07-26

Variant appearance in text: EGFR: 2065G>C; V689L

PubMed Link: 27460824

Variant Present in the following documents:

• 13073_2016_333_MOESM4_ESM.xlsx, sheet 1
• 13073_2016_333_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy

Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS

Publication Date: 2016

Variant appearance in text: EGFR: V689L

PubMed Link: 26785607

Variant Present in the following documents:

• Main text
• kcbt-17-03-1139235.pdf

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EGFR Exon 18 Mutations in East Asian Patients with Lung Adenocarcinomas: A Comprehensive Investigation of Prevalence, Clinicopathologic Characteristics and Prognosis.

Scientific Reports

Cheng, Chao C; Wang, Rui R; Li, Yuan Y; Pan, Yunjian Y; Zhang, Yang Y; Li, Hang H; Zheng, Difan D; Zheng, Shanbo S; Shen, Xuxia X; Sun, Yihua Y; Chen, Haiquan H

Publication Date: 2015-09-10

Variant appearance in text: EGFR: V689L

PubMed Link: 26354324

Variant Present in the following documents:

• Main text
• srep13959.pdf

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Pooled analysis of clinical outcome for EGFR TKI-treated patients with EGFR mutation-positive NSCLC.

Journal Of Cellular And Molecular Medicine

Paz-Ares, Luis L; Soulières, Denis D; Moecks, Joachim J; Bara, Ilze I; Mok, Tony T; Klughammer, Barbara B

Publication Date: 2014-08

Variant appearance in text: EGFR: V689L

PubMed Link: 25100284

Variant Present in the following documents:

• Main text
• jcmm0018-1519.pdf

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Frequency of driver mutations in lung adenocarcinoma from female never-smokers varies with histologic subtypes and age at diagnosis.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Zhang, Yang Y; Sun, Yihua Y; Pan, Yunjian Y; Li, Chenguang C; Shen, Lei L; Li, Yuan Y; Luo, Xiaoyang X; Ye, Ting T; Wang, Rui R; Hu, Haichuan H; Li, Hang H; Wang, Lei L; Pao, William W; Chen, Haiquan H

Publication Date: 2012-04-01

Variant appearance in text: EGFR: V689L

PubMed Link: 22317764

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genomic aberrations in lung adenocarcinoma in never smokers.

Plos One

Job, Bastien B; Bernheim, Alain A; Beau-Faller, Michèle M; Camilleri-Broët, Sophie S; Girard, Philippe P; Hofman, Paul P; Mazières, Julien J; Toujani, Saloua S; Lacroix, Ludovic L; Laffaire, Julien J; Dessen, Philippe P; Fouret, Pierre P; ,

Publication Date: 2010-12-06

Variant appearance in text: EGFR: Val689Leu

PubMed Link: 21151896

Variant Present in the following documents:

View BVdb publication page

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Clinical outcomes in non-small-cell lung cancer patients with EGFR mutations: pooled analysis.

Journal Of Cellular And Molecular Medicine

Paz-Ares, Luis L; Soulières, Denis D; Melezínek, Ivan I; Moecks, Joachim J; Keil, Lorenz L; Mok, Tony T; Rosell, Rafael R; Klughammer, Barbara B

Publication Date: 2010-01

Variant appearance in text: EGFR: V689L

PubMed Link: 20015198

Variant Present in the following documents:

• Main text
• jcmm0014-0051.pdf

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